Compounds > paroxetine
Page last updated: 2024-08-23

paroxetine and pregnanolone

paroxetine has been researched along with pregnanolone in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP1
Griffin, LD; Mellon, SH1
di Michele, F; Holsboer, F; Pasini, A; Romeo, E; Rupprecht, R; Ströhle, A; Yassouridis, A1
Pearson Murphy, BE1
Maayan, R; Nechmad, A; Poyurovsky, M; Ramadan, E; Spivak, B; Weizman, A1
Chi, H; Eguchi, S; Kawano, T; Soga, T; Yamazaki, F; Yokoyama, M1

Trials

1 trial(s) available for paroxetine and pregnanolone

ArticleYear
GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment.
    The American journal of psychiatry, 2002, Volume: 159, Issue:1

    Topics: Adult; Agoraphobia; Female; Follow-Up Studies; GABA-A Receptor Antagonists; Humans; Male; Middle Aged; Panic Disorder; Paroxetine; Pregnanolone; Receptors, GABA-A; Stereoisomerism; Treatment Outcome

2002

Other Studies

6 other study(ies) available for paroxetine and pregnanolone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-29, Volume: 93, Issue:22

    Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley

1996
Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-09, Volume: 96, Issue:23

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cholestenone 5 alpha-Reductase; COS Cells; DNA, Complementary; Fluoxetine; Humans; Molecular Sequence Data; Oxidoreductases; Paroxetine; Pregnanolone; Progesterone; Rats; RNA, Messenger; Selective Serotonin Reuptake Inhibitors

1999
Neuroactive steroid levels in patients with panic disorder.
    The American journal of psychiatry, 2003, Volume: 160, Issue:3

    Topics: Adult; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Menstrual Cycle; Panic Disorder; Paroxetine; Postmenopause; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Research Design

2003
Brain neurosteroid changes after paroxetine administration in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2003, Volume: 13, Issue:5

    Topics: 5-alpha-Dihydroprogesterone; Animals; Brain; Male; Mice; Paroxetine; Pregnanediones; Pregnanolone; Steroids; Time Factors

2003
The involvement of the neurosteroid allopregnanolone in the antihyperalgesic effect of paroxetine in a rat model of neuropathic pain.
    Neuroreport, 2011, Dec-21, Volume: 22, Issue:18

    Topics: Animals; Brain; Central Nervous System Stimulants; Disease Models, Animal; Hyperalgesia; Ligation; Male; Neuralgia; Pain Threshold; Paroxetine; Pregnanolone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord

2011