Page last updated: 2024-08-23

paroxetine and norfluoxetine

paroxetine has been researched along with norfluoxetine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dormann, SM; Haefeli, WE; Kerpen, CJ; Ketabi-Kiyanvash, N; Martin-Facklam, M; Weiss, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Bushnell, WD; Kreider, MS; Oakes, R; Wheadon, DE1
Bymaster, FP; Krushinski, JH; Mayle, DA; Reid, LR; Robertson, DW; Wong, DT1
Cua, W; Dominguez, RA; Kumar, AM1
Belpaire, FM; Brøsen, K; Rasmussen, BB; Temmerman, A; Wijnant, P1
Court, MH; Duan, SX; Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL1
Birnbaum, AK; Nelson, MH; Remmel, RP1
Chu, S; Metcalfe, CD1
Alves, G; Falcão, A; Llerena, A; Magalhães, P1
Doucet, N; Hudon Thibeault, AA; López de Los Santos, Y; Sanderson, JT; Vaillancourt, C1

Trials

2 trial(s) available for paroxetine and norfluoxetine

ArticleYear
A double-blind, randomized study to provide safety information on switching fluoxetine-treated patients to paroxetine without an intervening washout period.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:4

    Topics: Adult; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Half-Life; Humans; Incidence; Male; Paroxetine; Placebos; Substance Withdrawal Syndrome; Time Factors

1995
Lack of change in fluoxetine and norfluoxetine kinetics when switching from fluoxetine to paroxetine.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:4

    Topics: Adult; Aged; Cytochrome P-450 CYP2D6 Inhibitors; Depressive Disorder; Double-Blind Method; Drug Interactions; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors

1996

Other Studies

9 other study(ies) available for paroxetine and norfluoxetine

ArticleYear
Inhibition of P-glycoprotein by newer antidepressants.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Endothelium, Vascular; Humans; Reproducibility of Results; Swine; Transfection

2003
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Norfluoxetine enantiomers as inhibitors of serotonin uptake in rat brain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:4

    Topics: Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Brain; Dose-Response Relationship, Drug; Fluoxetine; Male; Paroxetine; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stereoisomerism

1993
The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:3

    Topics: 1-Naphthylamine; Adult; Anti-Arrhythmia Agents; Child; Citalopram; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Kinetics; Male; Methylation; Metoprolol; Microsomes, Liver; Oxidation-Reduction; Paroxetine; Quinidine; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10

    Topics: Antibodies; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Paroxetine; Piperazines; Sertraline; Triazoles

2000
Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors.
    Epilepsy research, 2001, Volume: 44, Issue:1

    Topics: Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Child, Preschool; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluoxetine; Humans; Hydroxylation; Male; Microsomes, Liver; Middle Aged; Paroxetine; Phenytoin; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2001
Analysis of paroxetine, fluoxetine and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup and liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2007, Sep-07, Volume: 1163, Issue:1-2

    Topics: Animals; Chromatography, Liquid; Fishes; Fluoxetine; Molecular Structure; Paroxetine; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry

2007
Therapeutic Drug Monitoring of Fluoxetine, Norfluoxetine and Paroxetine: A New Tool Based on Microextraction by Packed Sorbent Coupled to Liquid Chromatography.
    Journal of analytical toxicology, 2017, Sep-01, Volume: 41, Issue:7

    Topics: Chromatography, Liquid; Drug Monitoring; Fluoxetine; Humans; Paroxetine; Solid Phase Microextraction

2017
Serotonin and serotonin reuptake inhibitors alter placental aromatase.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 195

    Topics: Aromatase; Cells, Cultured; Citalopram; Female; Fluoxetine; Humans; Molecular Docking Simulation; Paroxetine; Placenta; Pregnancy; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Trophoblasts; Venlafaxine Hydrochloride

2019