Page last updated: 2024-08-23

paroxetine and lamotrigine

paroxetine has been researched along with lamotrigine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.09)18.2507
2000's9 (40.91)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Labbate, LA; Rubey, RN1
Calabrese, JR; Kimmel, SE; Rapport, DJ; Shelton, MD1
Grunze, H; Hörn, M; Hummel, B; Normann, C; Schärer, LO; Walden, J1
Berger, M; Fiebich, BL; Grunze, H; Lieb, K; Normann, C; Walden, J1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Jakovljevic, M; Kramaric, M; Muck-Seler, D; Mustapic, M; Nedic, G; Peles, AM; Pivac, N; Sagud, M1
Blom, MB; Hartong, EG; Mulder, P; Nolen, WA; Timmermans, MA; van der Loos, ML; van Noorden, MS; Vergouwen, AC; Vieta, E2
LeBlanc, SR; Ovanessian, MM; Parikh, SV1
Barbee, JG; Conrad, EJ; Jamhour, NJ; Reimherr, FW; Shelton, RC; Stewart, JW; Thompson, PM; Thompson, TR1
Bettica, P; Danhof, M; Della Pasqua, O; Gomeni, RA; Santen, G; van Zwet, E1
Asz-Sigall, D; Guzmán-Sánchez, D1

Reviews

3 review(s) available for paroxetine and lamotrigine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Controlled trials in bipolar I depression: focus on switch rates and efficacy.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9 Suppl 4

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Antimanic Agents; Bipolar Disorder; Controlled Clinical Trials as Topic; Double-Blind Method; Humans; Lamotrigine; Moclobemide; Paroxetine; Triazines

1999
Alopecias due to drugs and other skin and systemic disorders.
    Current problems in dermatology, 2015, Volume: 47

    Topics: Alopecia; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Dermatologic Agents; Dermatomycoses; Diet; Folliculitis; Herpes Zoster; HIV Infections; Humans; Isotretinoin; Lamotrigine; Lithium Compounds; Lupus Erythematosus, Systemic; Malnutrition; Mycosis Fungoides; Paroxetine; Sarcoidosis; Seasons; Skin Neoplasms; Starvation; Stress, Psychological; Syphilis; Triazines; Valproic Acid

2015

Trials

6 trial(s) available for paroxetine and lamotrigine

ArticleYear
Lamotrigine as adjunct to paroxetine in acute depression: a placebo-controlled, double-blind study.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Paroxetine; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome; Triazines

2002
Serum levels of substance P and response to antidepressant pharmacotherapy.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:5

    Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Humans; Lamotrigine; Paroxetine; Severity of Illness Index; Substance P; Surveys and Questionnaires; Triazines

2004
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine.
    Acta psychiatrica Scandinavica, 2010, Volume: 122, Issue:3

    Topics: Adult; Algorithms; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Middle Aged; Netherlands; Paroxetine; Psychiatric Status Rating Scales; Psychometrics; Triazines

2010
Long-term outcome of bipolar depressed patients receiving lamotrigine as add-on to lithium with the possibility of the addition of paroxetine in nonresponders: a randomized, placebo-controlled trial with a novel design.
    Bipolar disorders, 2011, Volume: 13, Issue:1

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Paroxetine; Treatment Outcome; Triazines; Young Adult

2011
A double-blind placebo-controlled trial of lamotrigine as an antidepressant augmentation agent in treatment-refractory unipolar depression.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:10

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Severity of Illness Index; Triazines

2011

Other Studies

13 other study(ies) available for paroxetine and lamotrigine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Lamotrigine for treatment-refractory bipolar disorder.
    The American journal of psychiatry, 1997, Volume: 154, Issue:9

    Topics: Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Male; Middle Aged; Paroxetine; Thyroxine; Triazines

1997
The effect of lamotrigine on platelet serotonin concentration in patients with bipolar depression.
    Psychopharmacology, 2008, Volume: 197, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bipolar Disorder; Blood Platelets; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Compounds; Middle Aged; Paroxetine; Prospective Studies; Psychiatric Status Rating Scales; Serotonin; Triazines

2008
Advancing bipolar disorder: key lessons from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2010, Volume: 55, Issue:3

    Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Bupropion; Combined Modality Therapy; Comorbidity; Database Management Systems; Humans; Inositol; Lamotrigine; Multicenter Studies as Topic; Paroxetine; Psychotherapy, Brief; Randomized Controlled Trials as Topic; Recurrence; Research Design; Risperidone; Smoking; Substance-Related Disorders; Suicide; Treatment Outcome; Triazines; United States; Vitamin B Complex

2010
From trial and error to trial simulation III: a framework for interim analysis in efficacy trials with antidepressant drugs.
    Clinical pharmacology and therapeutics, 2011, Volume: 89, Issue:4

    Topics: Antidepressive Agents; Bayes Theorem; Clinical Trials as Topic; Computer Simulation; Dose-Response Relationship, Drug; Humans; Lamotrigine; Paroxetine; Time Factors; Triazines

2011