Page last updated: 2024-08-23

paroxetine and hydrocodone

paroxetine has been researched along with hydrocodone in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Lurcott, G1
Carson, HJ; Eilers, SG1
Cipriano, A; Friedman, K; Harris, SC; Kapil, RP; Michels, G; Mondal, SA; Shet, M1

Reviews

1 review(s) available for paroxetine and hydrocodone

ArticleYear
The effects of the genetic absence and inhibition of CYP2D6 on the metabolism of codeine and its derivatives, hydrocodone and oxycodone.
    Anesthesia progress, 1998,Fall, Volume: 45, Issue:4

    Topics: Analgesics, Opioid; Anti-Arrhythmia Agents; Binding, Competitive; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Fluoxetine; Humans; Hydrocodone; Oxycodone; Paroxetine; Quinidine; Selective Serotonin Reuptake Inhibitors

1998

Trials

1 trial(s) available for paroxetine and hydrocodone

ArticleYear
Effects of paroxetine, a CYP2D6 inhibitor, on the pharmacokinetic properties of hydrocodone after coadministration with a single-entity, once-daily, extended-release hydrocodone tablet.
    Clinical therapeutics, 2015, Oct-01, Volume: 37, Issue:10

    Topics: Adult; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme System; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Hydrocodone; Hydromorphone; Male; Paroxetine; Tablets

2015

Other Studies

3 other study(ies) available for paroxetine and hydrocodone

ArticleYear
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Death from undiagnosed glioblastoma multiforme and toxic self-medication presenting with concurrent dysfunctional behavior.
    Journal of forensic and legal medicine, 2008, Volume: 15, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Brain Edema; Brain Neoplasms; Dextropropoxyphene; Female; Forensic Pathology; Forensic Toxicology; Glioblastoma; Headache Disorders, Secondary; Humans; Hydrocodone; Intracranial Hemorrhages; Mental Disorders; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Self Medication; Vitreous Body

2008