paroxetine has been researched along with fenfluramine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.06) | 18.7374 |
| 1990's | 21 (63.64) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R | 1 |
| Abraham, P; Carroll, FI; Cline, EJ; Dannals, RF; Kuhar, MJ; Lewin, AH; Ricaurte, GA; Scheffel, U | 1 |
| Bell, J; Whitaker-Azmitia, PM; Zhang, XN | 1 |
| Peroutka, SJ; Wagner, J | 1 |
| Johnson, MP; Nichols, DE | 1 |
| Appel, NM; Contrera, JF; De Souza, EB; Mitchell, WM | 1 |
| Koshikawa, F; Koshikawa, N; Stephenson, JD | 1 |
| Fuller, RW | 1 |
| Rowland, NE | 2 |
| Dodd, PR; Westphalen, RI | 1 |
| Mahatme, A; Rowland, NE; Semple-Rowland, SL | 1 |
| Carpenter, LL; Epperson, CN; McDougle, CJ; Price, LH | 1 |
| Cowen, PJ; McTavish, SF; Williamson, DJ | 1 |
| Burrows, GD; Nathan, PJ; Norman, TR | 1 |
| Colado, MI; Green, AR; Misra, A; Murray, TK; Williams, JL | 1 |
| Colado, MI; Granados, R; Green, AR; Murray, TK; O'Shea, E | 1 |
| Auerbach, SB; Gundlah, C; Heal, DJ; Martin, KF | 1 |
| Cozzi, NV; Frescas, S; Huang, X; Marona-Lewicka, D; Nichols, DE | 1 |
| Auerbach, SB; Gundlah, C; Simon, LD | 1 |
| Bell, CJ; Malizia, AL; Nutt, DJ | 1 |
| Aguilera, J; Gil, C; Inserte, J; Najib, A; Pelliccioni, P | 1 |
| Béïque, JC; Blier, P; de Montigny, C; Debonnel, G | 1 |
| Behr, J; Gentsch, K; Heinemann, U; Schmitz, B | 1 |
| Antonelli, T; Fernandez, M; Ferraro, L; Fuxe, K; Rambert, FA; Tanganelli, S | 1 |
| Antonelli, T; Bebe, BW; Ferraro, L; Fuxe, K; Rambert, FA; Tanganelli, S; Tomasini, MC | 1 |
| Dulchin, MC; Ellis, SP; Li, S; Malone, KM; Mann, JJ; Oquendo, MA | 1 |
| Cooper, J; Greenslade, RG; Mitchell, SN | 1 |
| Isbester, PK; Salsbury, JS | 1 |
| Amitani, H; Asakawa, A; Fujimiya, M; Fujitsuka, N; Hayashi, M; Inui, A; Kojima, S; Sameshima, M | 1 |
| Aznar, S; Knudsen, GM; Licht, CL; Marcussen, AB; Overstreet, DH; Wegener, G | 1 |
3 review(s) available for paroxetine and fenfluramine
| Article | Year |
|---|---|
Biochemical pharmacology of the serotonin system.
Topics: Alanine; Brain; Citalopram; Clomipramine; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Monoamine Oxidase Inhibitors; Neurons; Oximes; p-Chloroamphetamine; Paroxetine; Piperidines; Propylamines; Receptors, Serotonin; Reserpine; Serotonin; Serotonin Antagonists; Synapses; Tetrabenazine; Zimeldine | 1986 |
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Costs and Cost Analysis; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Lithium; Obsessive-Compulsive Disorder; Paroxetine; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan | 1996 |
Brain mechanisms of social anxiety disorder.
Topics: Animals; Brain; Caffeine; Carbon Dioxide; Cholecystokinin; Dopamine; Fear; Fenfluramine; Humans; Panic Disorder; Paroxetine; Phobic Disorders; Piperazines; Rats; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin; Tomography, Emission-Computed | 1998 |
2 trial(s) available for paroxetine and fenfluramine
| Article | Year |
|---|---|
Nocturnal plasma melatonin concentrations in healthy volunteers: effect of single doses of d-fenfluramine, paroxetine, and ipsapirone.
Topics: Administration, Oral; Adolescent; Adult; Fenfluramine; Humans; Light; Male; Melatonin; Paroxetine; Pineal Gland; Pyrimidines; Serotonin Receptor Agonists; Single-Blind Method | 1996 |
Prolactin response to dl-fenfluramine challenge before and after treatment with paroxetine.
Topics: Aged; Biomarkers; Depressive Disorder; Female; Fenfluramine; Humans; Male; Middle Aged; Paroxetine; Prolactin; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors | 2001 |
28 other study(ies) available for paroxetine and fenfluramine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1992 |
[123/125I]RTI-55, an in vivo label for the serotonin transporter.
Topics: Animals; Biological Transport, Active; Cocaine; Fenfluramine; Histocytochemistry; Indicators and Reagents; Iodine Radioisotopes; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tomography, Emission-Computed, Single-Photon | 1992 |
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes | 1992 |
Neurochemistry and neurotoxicity of substituted amphetamines.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Designer Drugs; Fenfluramine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin | 1990 |
Comparative serotonin neurotoxicity of the stereoisomers of fenfluramine and norfenfluramine.
Topics: Animals; Biogenic Monoamines; Fenfluramine; Frontal Lobe; Hippocampus; Male; Neurons; Norfenfluramine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1990 |
Effects of high-dose fenfluramine treatment on monoamine uptake sites in rat brain: assessment using quantitative autoradiography.
Topics: Animals; Autoradiography; Biogenic Monoamines; Brain; Fenfluramine; Male; Mazindol; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tritium | 1990 |
Effects of antidepressant drug combinations on cortical 5-HT2 receptors and wet-dog shakes in rats.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Carbidopa; Cerebral Cortex; Citalopram; Drug Interactions; Fenfluramine; Male; Methoxydimethyltryptamines; Paroxetine; Phenelzine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Time Factors | 1985 |
Long-term administration of dexfenfluramine to genetically obese (ob/ob) and lean mice: body weight and brain serotonin changes.
Topics: Animals; Blood Glucose; Body Weight; Brain Chemistry; Corticosterone; Dietary Fats; Female; Fenfluramine; Mice; Mice, Inbred C57BL; Mice, Obese; Norfenfluramine; Obesity; Paroxetine; Serotonin | 1994 |
Tolerance to the anorectic effect of dexfenfluramine in rats: role of serotonin, cholecystokinin, and neuropeptide Y.
Topics: Animals; Appetite Depressants; Brain; Brain Chemistry; Cholecystokinin; Drug Tolerance; Eating; Female; Fenfluramine; Food Deprivation; Male; Metergoline; Neuropeptide Y; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Weight Loss | 1994 |
The regeneration of d,l-fenfluramine-destroyed serotonergic nerve terminals.
Topics: Animals; Binding Sites; Fenfluramine; Male; Nerve Regeneration; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Membranes; Synaptosomes | 1993 |
Effects of dexfenfluramine or 5,7-dihydroxytryptamine on tryptophan hydroxylase and serotonin transporter mRNAS in rat dorsal raphe.
Topics: 5,7-Dihydroxytryptamine; Animals; Carrier Proteins; Enzyme Induction; Fenfluramine; Gene Expression Regulation; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Polymerase Chain Reaction; Raphe Nuclei; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase | 1996 |
Effect of valine on 5-HT neurotransmission and mood.
Topics: 1-Naphthylamine; Adult; Affect; Amino Acids, Branched-Chain; Amitriptyline; Analysis of Variance; Antidepressive Agents; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Fenfluramine; Humans; Lithium; Male; Paroxetine; Prolactin; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Synaptic Transmission; Valine | 1996 |
The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine.
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Cyclic N-Oxides; Fenfluramine; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Neurons; Nitrogen Oxides; p-Chloroamphetamine; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Spin Labels; Spin Trapping | 1996 |
In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine.
Topics: Animals; Biogenic Monoamines; Body Temperature; Brain Chemistry; Fenfluramine; Free Radical Scavengers; Free Radicals; Hippocampus; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; p-Chloroamphetamine; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Agents | 1997 |
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclobutanes; Fenfluramine; Fluoxetine; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential.
Topics: Animals; Appetite Depressants; Body Weight; Brain Chemistry; Discrimination, Psychological; Fenfluramine; In Vitro Techniques; Indans; Male; Nervous System Diseases; Neurotransmitter Uptake Inhibitors; Norfenfluramine; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Serotonin; Synaptosomes | 1998 |
Differences in hypothalamic serotonin between estrous phases and gender: an in vivo microdialysis study.
Topics: Animals; Diestrus; Dose-Response Relationship, Drug; Estrus; Extracellular Space; Female; Fenfluramine; Hypothalamus; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Sex Characteristics | 1998 |
Inhibition by tetanus toxin of sodium-dependent, high-affinity [3H]5-hydroxytryptamine uptake in rat synaptosomes.
Topics: Animals; Biological Transport; Botulinum Toxins; Brain; Captopril; Fenfluramine; Imipramine; Kinetics; Male; Organ Specificity; Paroxetine; Phenanthrolines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sodium; Synaptosomes; Temperature; Tetanus Toxin; Tritium | 1999 |
Venlafaxine: discrepancy between in vivo 5-HT and NE reuptake blockade and affinity for reuptake sites.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Animals; Binding Sites; Cyclohexanols; Desipramine; Fenfluramine; Hippocampus; In Vitro Techniques; Locus Coeruleus; Male; Neurons; Norepinephrine; Paroxetine; Piperazines; Piperoxan; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Tyramine; Venlafaxine Hydrochloride | 1999 |
Fenfluramine blocks low-Mg2+-induced epileptiform activity in rat entorhinal cortex.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe; Extracellular Space; Fenfluramine; Hippocampus; In Vitro Techniques; Magnesium; Paroxetine; Piperazines; Presynaptic Terminals; Pyridines; Rats; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists | 2000 |
Amplification of cortical serotonin release: a further neurochemical action of the vigilance-promoting drug modafinil.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cerebral Cortex; Fenfluramine; Male; Modafinil; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 2000 |
Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs.
Topics: Animals; Benzhydryl Compounds; Fenfluramine; Fluoxetine; Frontal Lobe; In Vitro Techniques; Male; Modafinil; Neuroprotective Agents; Paroxetine; Potassium; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sleep; Synaptic Transmission; Synaptosomes; Tritium | 2001 |
LY393558, a 5-hydroxytryptamine reuptake inhibitor and 5-HT(1B/1D) receptor antagonist: effects on extracellular levels of 5-hydroxytryptamine in the guinea pig and rat.
Topics: Administration, Oral; Animals; Cyclic S-Oxides; Dose-Response Relationship, Drug; Extracellular Space; Female; Fenfluramine; Fluoxetine; Frontal Lobe; Guinea Pigs; Hypothalamus; Injections, Intraperitoneal; Male; Oxadiazoles; Paroxetine; Piperazines; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Tetrodotoxin; Thiadiazines; Time Factors | 2001 |
Quantitative 1H NMR method for the routine spectroscopic determination of enantiomeric purity of active pharmaceutical ingredients fenfluramine, sertraline, and paroxetine.
Topics: Chemistry, Pharmaceutical; Fenfluramine; Magnetic Resonance Spectroscopy; Molecular Structure; Paroxetine; Protons; Reference Standards; Sertraline; Stereoisomerism | 2005 |
Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin.
Topics: Animals; Drugs, Chinese Herbal; Eating; Fenfluramine; Fluoxetine; Fluvoxamine; Gastrointestinal Motility; Ghrelin; Growth Hormone; Injections, Intraventricular; Male; Oligopeptides; Paroxetine; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Ghrelin; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2009 |
The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration.
Topics: Animals; Antidepressive Agents, Second-Generation; Autoradiography; Brain; Citalopram; Depression; Disease Models, Animal; Fenclonine; Fenfluramine; Fluorobenzenes; Freezing Reaction, Cataleptic; Male; Paroxetine; Piperidines; Protein Binding; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Swimming; Time Factors; Tritium | 2009 |