Page last updated: 2024-08-23

paroxetine and carbamazepine

paroxetine has been researched along with carbamazepine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.63)18.2507
2000's11 (28.95)29.6817
2010's24 (63.16)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Abdelrahman, A; Dosa, S; El-Tayeb, A; Hinz, S; Müller, CE; Tian, M; Weinhausen, S; Weyer, S1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Apelland, T; Dietrichson, T; Gedde-Dahl, T1
Bowden, CL; Evans, DL; Gergel, IP; Gyulai, L; Nemeroff, CB; Oakes, R; Pitts, CD; Sachs, GS1
Asnis, GM; Gabbay, V; O'Dowd, MA1
Koyama, T; Suzuki, K1
Bel Reverter, M; Hidalgo Mora, JJ; Palop Larrea, V; Sempere i Verdú, E1
Antonetti, DA; Maines, LW; Smith, CD; Wolpert, EB1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX1
Ecker, GF; Freissmuth, M; Sarker, S; Sitte, HH; Steiner, I; Sucic, S; Weissensteiner, R1
Castberg, I; Davies, SJ; Lennard, MS; Lewis, G; Spigset, O; Taylor, S; Westin, AA1
Holsboer, F; Perisic, T; Rein, T; Yu, S; Zimmermann, N; Zschocke, J1
Akiyoshi, J; Hanada, H; Ishitobi, Y; Kanehisa, M; Kawano, Y; Shimomura, T; Tanaka, Y; Tsuru, J1
Aceña, J; Barceló, D; Esplugas, S; González, O; Justo, A; Pérez, S; Sans, C1
Harada, S; Matsuura, W; Tokuyama, S1
Calisto, V; Esteves, VI; Gil, MV; Jaria, G; Oliveira, JABP; Otero, M; Santos, SM; Silva, CP1
Baandrup, L; Ebdrup, BH; Glenthøj, BY; Gluud, C; Lindschou, J; Rasmussen, JØ1
Calisto, V; Esteves, VI; Gil, MV; Jaria, G; Otero, M; Silva, CP1
Kenda, M; Sollner Dolenc, M; Zore, T1
Abajo, Z; Domingo-Echaburu, S; Jimenez, A; Lertxundi, U; Orive, G; Segura, Y; Valcárcel, Y1

Reviews

3 review(s) available for paroxetine and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pharmacokinetics and drug interaction of antidepressants and anti-manic drugs].
    Ryoikibetsu shokogun shirizu, 2003, Issue:38

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antimanic Agents; Carbamazepine; Cyclopropanes; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Isoenzymes; Lithium; Milnacipran; Paroxetine; Selective Serotonin Reuptake Inhibitors; Valproic Acid

2003
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users.
    The Cochrane database of systematic reviews, 2018, Mar-15, Volume: 3

    Topics: Adult; Antidepressive Agents; Aspartic Acid; Benzodiazepines; Buspirone; Carbamazepine; Ethylamines; Flumazenil; Homeopathy; Humans; Imidazoles; Lithium Compounds; Melatonin; Paroxetine; Pregabalin; Progesterone; Pyridines; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Sulfides; Withholding Treatment

2018

Trials

1 trial(s) available for paroxetine and carbamazepine

ArticleYear
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression.
    The American journal of psychiatry, 2001, Volume: 158, Issue:6

    Topics: Adult; Aged; Ambulatory Care; Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Valproic Acid

2001

Other Studies

34 other study(ies) available for paroxetine and carbamazepine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Carbamazepine derivatives with P2X4 receptor-blocking activity.
    Bioorganic & medicinal chemistry, 2014, Feb-01, Volume: 22, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbamazepine; Chemistry Techniques, Synthetic; Dibenzazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Mice; Purinergic P2X Receptor Antagonists; Rats; Receptors, Purinergic P2X4; Structure-Activity Relationship

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Serotonin syndrome with fatal outcome caused by selective serotonin reuptake inhibitors].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1999, Feb-20, Volume: 119, Issue:5

    Topics: Anticonvulsants; Antipsychotic Agents; Butyrophenones; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Fatal Outcome; Humans; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Trimeprazine

1999
Combined antidepressant treatment: a risk factor for switching in bipolar patients.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:4

    Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Bupropion; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Middle Aged; Paroxetine; Risk Factors; Treatment Outcome

2002
[Hyponatremia due to carbamazepine and paroxetine].
    Atencion primaria, 2004, May-15, Volume: 33, Issue:8

    Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Hyponatremia; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2004
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells.
    Neuropharmacology, 2005, Volume: 49, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carbamazepine; Cattle; Cell Separation; Cells, Cultured; Cerebral Cortex; Clozapine; Endothelial Cells; Hydrocortisone; Paroxetine; Phenytoin; Rats; Retina; Selective Serotonin Reuptake Inhibitors

2005
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles

2008
The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.
    Molecular pharmacology, 2010, Volume: 78, Issue:6

    Topics: Amphetamines; Antidepressive Agents, Tricyclic; Binding Sites; Carbamazepine; HEK293 Cells; Humans; Ibogaine; Paroxetine; Protein Binding; Serotonin Plasma Membrane Transport Proteins

2010
Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies.
    Acta psychiatrica Scandinavica, 2010, Volume: 122, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Antifungal Agents; Antimalarials; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Clopenthixol; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Fluoxetine; Humans; In Vitro Techniques; Ketoconazole; Male; Methotrimeprazine; Microsomes, Liver; Middle Aged; Paroxetine; Quinidine

2010
Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels.
    The Biochemical journal, 2012, Nov-15, Volume: 448, Issue:1

    Topics: Animals; Antidepressive Agents; Astrocytes; Carbamazepine; Cells, Cultured; Cerebral Cortex; Citalopram; Cyclohexanols; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Glycolipids; Histone-Lysine N-Methyltransferase; Imipramine; Indoles; Maleimides; Mice; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Paroxetine; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Venlafaxine Hydrochloride

2012
Hippocampal agenesis in an individual who engaged in violent criminal behaviors after discontinuing carbamazepine and paroxetine treatment.
    Journal of forensic sciences, 2013, Volume: 58, Issue:1

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Antimanic Agents; Brain Mapping; Carbamazepine; Crime; Disruptive, Impulse Control, and Conduct Disorders; Forensic Psychiatry; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Medication Adherence; Paroxetine; Sexual Behavior; Substance Withdrawal Syndrome; Thalamus; Young Adult

2013
Pharmaceuticals and organic pollution mitigation in reclamation osmosis brines by UV/H2O2 and ozone.
    Journal of hazardous materials, 2013, Dec-15, Volume: 263 Pt 2

    Topics: Atenolol; Carbamazepine; Filtration; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Osmosis; Oxygen; Ozone; Paroxetine; Pharmaceutical Preparations; Salts; Trimethoprim; Ultraviolet Rays; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical; Water Purification

2013
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
Production of highly efficient activated carbons from industrial wastes for the removal of pharmaceuticals from water-A full factorial design.
    Journal of hazardous materials, 2019, 05-15, Volume: 370

    Topics: Adsorption; Carbamazepine; Charcoal; Industrial Waste; Paper; Paroxetine; Sulfamethoxazole; Waste Disposal, Fluid; Water Pollutants, Chemical

2019
Obtaining granular activated carbon from paper mill sludge - A challenge for application in the removal of pharmaceuticals from wastewater.
    The Science of the total environment, 2019, Feb-25, Volume: 653

    Topics: Adsorption; Ammonium Compounds; Carbamazepine; Charcoal; Industrial Waste; Lignin; Paroxetine; Printing; Sewage; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2019
Effects of central nervous system drugs on androgen, estrogen α, glucocorticoid, and thyroid receptors.
    Chemico-biological interactions, 2022, Aug-25, Volume: 363

    Topics: Androgens; Animals; Carbamazepine; Central Nervous System Agents; CHO Cells; Clonazepam; Cricetinae; Cricetulus; Estrogen Receptor alpha; Estrogens; Fluoxetine; Glucocorticoids; Luciferases, Firefly; Paroxetine; Receptors, Androgen; Receptors, Glucocorticoid; Sertraline; Thyroid Gland

2022
Analyzing the potential environmental impact of NIOSH list of hazardous drugs (group 2).
    The Science of the total environment, 2023, May-15, Volume: 873

    Topics: Animals; Anticonvulsants; Carbamazepine; Environment; Hazardous Substances; Humans; National Institute for Occupational Safety and Health, U.S.; Paroxetine; Pharmaceutical Preparations; United States; Water Pollutants, Chemical

2023