Page last updated: 2024-08-23

paroxetine and alprazolam

paroxetine has been researched along with alprazolam in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's16 (57.14)29.6817
2010's9 (32.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Court, MH; Duan, SX; Greenblatt, DJ; Harmatz, JS; Shader, RI; von Moltke, LL1
Hartman, EE; Parker, RA1
Rickels, K; Rynn, M1
Barbanoj, M; Calvo, G; Dal-Ré, R; García-Gea, C; Luque, A; Morte, A1
Barbanoj, MJ; Clos, S; Dal-Ré, R; Giménez, S; Lorenzo, JL; Luque, A; Morte, A; Romero, S1
Girardi, P; Kotzalidis, GD; Lazanio, S; Manfredi, G; Ruberto, A; Tatarelli, R1
Espa-Cervená, K; Houbová, P; Novák, T; Pasková, B; Prasko, J; Vyskocilová, J; Záleský, R1
Hogg, S; Jessa, M; Michan, L1
Fujita, K; Ichihashi, K; Inoue, K; Okazaki, Y; Tanii, H1
Corace, E; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Garcia, CS1
Celik, L; Kaynak, S; Kaynak, T; Kocak, N; Ozerdem, A1
Ahn, SC; Choi, TK; Lee, SH; Lee, YJ; Suh, SY; Yook, KH1
Matsumoto, H; Tamai, Y1
Juřica, J; Žourková, A1
Cinconze, M; Concerto, C; Costanzo, MC; Signorelli, MS1
Aragão, I; Cardoso, T; Guedes, F; Maia, JM1
Orlando, JM1
Coimbra, JPC; Coimbra, NC; de Freitas, RL; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Laure, CJ; Paschoalin-Maurin, T1
Barbui, C; Bighelli, I; Caldwell, DM; Cipriani, A; Davies, SJ; Dawson, S; Dias, S; Furukawa, TA; Guaiana, G; Imai, H; Koesters, M; Meader, N; Pompoli, A; Robertson, L; Tajika, A1

Reviews

3 review(s) available for paroxetine and alprazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacotherapy of generalized anxiety disorder.
    The Journal of clinical psychiatry, 2002, Volume: 63 Suppl 14

    Topics: Algorithms; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Buspirone; Combined Modality Therapy; Cyclohexanols; Delayed-Action Preparations; Drug Administration Schedule; Humans; Paroxetine; Psychotherapeutic Processes; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Venlafaxine Hydrochloride

2002
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
    The Cochrane database of systematic reviews, 2023, 11-28, Volume: 11

    Topics: Adult; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipramine; Clonazepam; Desipramine; Diazepam; Fluoxetine; Humans; Network Meta-Analysis; Panic Disorder; Paroxetine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Venlafaxine Hydrochloride

2023

Trials

5 trial(s) available for paroxetine and alprazolam

ArticleYear
Lack of pharmacologic interaction between paroxetine and alprazolam at steady state in healthy volunteers.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:3

    Topics: Adult; Alprazolam; Analysis of Variance; Area Under Curve; Chi-Square Distribution; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Humans; Male; Multivariate Analysis; Paroxetine; Psychomotor Performance

2004
Sleep laboratory study on single and repeated dose effects of paroxetine, alprazolam and their combination in healthy young volunteers.
    Neuropsychobiology, 2005, Volume: 51, Issue:3

    Topics: Adult; Alprazolam; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Clinical Laboratory Techniques; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Evaluation Studies as Topic; Female; Humans; Linear Models; Male; Paroxetine; Polysomnography; Self-Assessment; Sleep; Sleep, REM; Surveys and Questionnaires; Time Factors; Wakefulness

2005
Influence of personality disorder on the treatment of panic disorder--comparison study.
    Neuro endocrinology letters, 2005, Volume: 26, Issue:6

    Topics: Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Panic Disorder; Paroxetine; Personality Disorders; Personality Inventory; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors

2005
Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder.
    Journal of psychosomatic research, 2007, Volume: 62, Issue:2

    Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Combined Modality Therapy; Fluvoxamine; Humans; Meditation; Paroxetine; Program Development; Self Care; Sertraline; Stress, Psychological; Surveys and Questionnaires

2007
Dynamics and persistence of CYP2D6 inhibition by paroxetine.
    Journal of clinical pharmacy and therapeutics, 2013, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Alprazolam; Anxiety; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Depression; Dextromethorphan; Dextrorphan; Double-Blind Method; Female; Humans; Male; Middle Aged; Paroxetine; Young Adult

2013

Other Studies

20 other study(ies) available for paroxetine and alprazolam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: Alprazolam; Biotransformation; Culture Techniques; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors

1995
An 87-year-old woman taking a benzodiazepine, 1 year later.
    JAMA, 1999, Nov-24, Volume: 282, Issue:20

    Topics: Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Depression; Drug Therapy, Combination; Female; Humans; Paroxetine; Risk

1999
Postpartum depression without delivering a child?
    Acta psychiatrica Scandinavica, 2005, Volume: 112, Issue:3

    Topics: Alprazolam; Anti-Anxiety Agents; Depression, Postpartum; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Family; Female; Humans; Hysterectomy; Middle Aged; Paroxetine; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Suicide, Attempted

2005
Prediction of anti-panic properties of escitalopram in the dorsal periaqueductal grey model of panic anxiety.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: Adrenergic alpha-Antagonists; Alprazolam; Animals; Anxiety; Citalopram; Dose-Response Relationship, Drug; Electric Stimulation; Fluoxetine; Hypnotics and Sedatives; Male; Motor Activity; Panic Disorder; Paroxetine; Periaqueductal Gray; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stereotaxic Techniques; Yohimbine

2006
Possible neuroleptic malignant syndrome related to concomitant treatment with paroxetine and alprazolam.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6

    Topics: Aged; Alprazolam; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Male; Neuroleptic Malignant Syndrome; Paroxetine; Psychiatric Status Rating Scales

2006
Generalised urticaria in a young woman treated with clomipramine and after ingestion of codfish.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:4

    Topics: Adult; Alprazolam; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Clomipramine; Drug Eruptions; Female; Food-Drug Interactions; Gadus morhua; Humans; Hypnotics and Sedatives; Meat; Obsessive-Compulsive Disorder; Paroxetine; Urticaria

2006
Disappointment of patients on antidepressant therapy after excimer laser treatment.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:10

    Topics: Adult; Alprazolam; Antidepressive Agents; Dry Eye Syndromes; Female; Humans; Keratomileusis, Laser In Situ; Middle Aged; Mydriasis; Myopia; Paroxetine; Patient Satisfaction; Patients; Sertraline; Vision Disorders

2006
11-year-old boy with panic disorder responding to paroxetine.
    The Tokai journal of experimental and clinical medicine, 2007, Mar-20, Volume: 32, Issue:1

    Topics: Alprazolam; Anti-Anxiety Agents; Child; Humans; Male; Neuropsychological Tests; Panic Disorder; Paroxetine; Selective Serotonin Reuptake Inhibitors

2007
What kind of diagnosis in a case of mobbing: post-traumatic stress disorder or adjustment disorder?
    BMJ case reports, 2013, Jun-11, Volume: 2013

    Topics: Adjustment Disorders; Alprazolam; Anti-Anxiety Agents; Crowding; Diagnosis, Differential; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Middle Aged; Paroxetine; Pregabalin; Stress Disorders, Post-Traumatic

2013
Eosinophilic pneumonia presenting as life-threatening ARDS.
    BMJ case reports, 2015, Jul-06, Volume: 2015

    Topics: Adult; Alprazolam; Antidepressive Agents, Second-Generation; Caustics; Cough; Drug Therapy, Combination; Eosinophilia; Eosinophils; Female; Glucocorticoids; Humans; Lye; Paroxetine; Prednisone; Pulmonary Eosinophilia; Radiography, Thoracic; Respiratory Distress Syndrome; Suicide, Attempted; Treatment Outcome; Valproic Acid

2015
Animal Behavior Case of the Month.
    Journal of the American Veterinary Medical Association, 2017, 11-01, Volume: 251, Issue:9

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Diazepam; Dog Diseases; Dogs; Fear; Fluoxetine; Gabapentin; Male; Noise; Paroxetine; Phobic Disorders

2017
The Rodent-versus-wild Snake Paradigm as a Model for Studying Anxiety- and Panic-like Behaviors: Face, Construct and Predictive Validities.
    Neuroscience, 2018, 01-15, Volume: 369

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Elapidae; Escape Reaction; Limbic System; Male; Mesocricetus; Models, Animal; Panic; Panic Disorder; Paroxetine; Predatory Behavior; Proto-Oncogene Proteins c-fos

2018