Compounds > pargyline

pargyline and tolcapone

pargyline has been researched along with tolcapone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brown, E; Cumming, P; Damsma, G; Fibiger, H1
Friedgen, B; Graefe, KH; Wölfel, R1
Azevedo, I; Martel, F1
Männistö, PT; Törnwall, M; Tuomainen, P1
Benoit-Marand, M; Gonon, F; Jaber, M1
Aonurm-Helm, A; Kaenmaki, M; Mannisto, PT; Tammimaki, A1

Other Studies

11 other study(ies) available for pargyline and tolcapone

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Formation and clearance of interstitial metabolites of dopamine and serotonin in the rat striatum: an in vivo microdialysis study.
    Journal of neurochemistry, 1992, Volume: 59, Issue:5

    Topics: Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dialysis; Dopamine; Drug Combinations; Extracellular Space; Hydroxyindoleacetic Acid; Male; Nitrophenols; Pargyline; Probenecid; Rats; Rats, Wistar; Serotonin; Tolcapone

1992
The contribution by monoamine oxidase and catechol-O-methyltransferase to the total-body and pulmonary plasma clearance of catecholamines.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:2

    Topics: Animals; Benzophenones; Catechol O-Methyltransferase; Catecholamines; Dopamine; Female; Male; Monoamine Oxidase; Nitrophenols; Norepinephrine; Pargyline; Pulmonary Circulation; Rabbits; Tolcapone

1996
The fate of [3H]-(-)-noradrenaline in the perfused rat liver.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Corticosterone; In Vitro Techniques; Liver; Male; Monoamine Oxidase Inhibitors; Nitrophenols; Norepinephrine; Pargyline; Rats; Rats, Wistar; Tolcapone; Tritium

1995
Minor effect of tolcapone, a catechol-O-methyltransferase inhibitor, on extracellular dopamine levels modified by amphetamine or pargyline: a microdialysis study in anaesthetized rats.
    Pharmacology & toxicology, 1996, Volume: 78, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Anesthesia, General; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dopamine; Dopamine Agents; Enzyme Inhibitors; Extracellular Space; Homovanillic Acid; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrophenols; Pargyline; Rats; Rats, Wistar; Tolcapone

1996
Release and elimination of dopamine in vivo in mice lacking the dopamine transporter: functional consequences.
    The European journal of neuroscience, 2000, Volume: 12, Issue:8

    Topics: Animals; Autoreceptors; Benzophenones; Brain Chemistry; Carrier Proteins; Catechol O-Methyltransferase Inhibitors; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Electrochemistry; Electrophysiology; Enzyme Inhibitors; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Neurons; Nitrophenols; Nucleus Accumbens; Pargyline; Tolcapone

2000
Elimination of extracellular dopamine in the medial prefrontal cortex of conscious mice analysed using selective enzyme and uptake inhibitors.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Animals; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dopamine; Female; Homovanillic Acid; Male; Mice, Inbred C57BL; Mice, Knockout; Monoamine Oxidase Inhibitors; Morpholines; Nitrophenols; Pargyline; Prefrontal Cortex; Reboxetine; Synaptosomes; Tolcapone

2016