pargyline and proadifen

pargyline has been researched along with proadifen in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Baraldi, M; Grandison, L; Guidotti, A1
DeMaster, EG; Nagasawa, HT1
McKillop, D; Powis, G1
Pai, KS; Ravindranath, V1
Rand, MJ; Trinker, FR2
Fujimoto, M; Kitahara, A; Miyao, K; Ogo, T1
Eade, NR; Renton, KW1
Gessner, PK; Zaleska, MM1
Collier, JG; Morinan, A1
DeMaster, EG; Kaplan, E; Nagasawa, HT; Shirota, FN; Sumner, HW1
DeMaster, EG; Nagasawa, HT; Shirota, FN1

Other Studies

13 other study(ies) available for pargyline and proadifen

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Distribution and metabolism of muscimol in the brain and other tissues of the rat.
    Neuropharmacology, 1979, Volume: 18, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Brain; Injections, Intravenous; Injections, Intraventricular; Male; Muscimol; Oxazoles; Pargyline; Proadifen; Rats; Time Factors; Tissue Distribution

1979
Inhibition of aldehyde dehydrogenase by propiolaldehyde, a possible metabolite of pargyline.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 21, Issue:3

    Topics: Acetylcholine; Aldehyde Oxidoreductases; Aldehydes; Alkynes; Animals; Male; Mitochondria, Liver; Pargyline; Proadifen; Rats; Time Factors

1978
The metabolism and binding of catecholamines by the hepatic microsomal fraction of the rat.
    Biochemical Society transactions, 1976, Volume: 4, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Animals; Binding Sites; Carbon Monoxide; Epinephrine; Microsomes, Liver; Norepinephrine; Pargyline; Proadifen; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet

1976
Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducer: in vitro studies with brain slices.
    Brain research, 1991, Aug-02, Volume: 555, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; MPTP Poisoning; NADPH-Ferrihemoprotein Reductase; Pargyline; Phenobarbital; Piperazines; Piperonyl Butoxide; Proadifen; Selegiline

1991
The effect of nialamide, pargyline and tranylcypromine on the removal of amphetamine by the perfused liver.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:7

    Topics: Amphetamine; Animals; Cats; In Vitro Techniques; Liver; Microsomes, Liver; Nialamide; Pargyline; Perfusion; Proadifen; Tranylcypromine

1970
[Analgesic effect of 2-methylaminoethyl 2,3-dihydrobenzofuran (EPS-4032); mode of action in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:6

    Topics: 5-Hydroxytryptophan; Aminopyrine; Analgesics; Animals; Benzofurans; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Drug Tolerance; Lethal Dose 50; Levallorphan; Male; Mice; Morphine; Nialamide; Pargyline; Phenobarbital; Proadifen; Reserpine; Tetrabenazine; Time Factors

1971
Effect of monoamine oxidase inhibitors on the N-demethylation and hydrolysis of meperidine.
    Biochemical pharmacology, 1970, Volume: 19, Issue:7

    Topics: Amphetamine; Animals; Dealkylation; Dextroamphetamine; Ethanol; Hydrolysis; In Vitro Techniques; Iproniazid; Kinetics; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Proadifen; Rats; Statistics as Topic; Stereoisomerism; Tranylcypromine

1970
The mechanism of the augmentation of responses to indirectly acting sympathomimetic amines by monoamine oxidase inhibitors.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Amphetamine; Animals; Blood Pressure; Cats; Drug Synergism; Epinephrine; Methyldopa; Nialamide; Norepinephrine; Pargyline; Proadifen; Rats; Tranylcypromine; Tyramine

1968
Metabolism of [14C]paraldehyde in mice in vivo, generation and trapping of acetaldehyde.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:3

    Topics: Acetaldehyde; Animals; Biotransformation; Breath Tests; Cyanamide; Ditiocarb; Kinetics; Male; Mice; Mice, Inbred BALB C; Models, Biological; Paraldehyde; Pargyline; Proadifen

1983
Effects of pargyline and SKF-525A on brain N,N-dimethyltryptamine concentrations and hyperactivity in mice.
    Psychopharmacology, 1981, Volume: 75, Issue:2

    Topics: Animals; Brain; Drug Synergism; Humans; Hyperkinesis; Male; Mice; N,N-Dimethyltryptamine; Pargyline; Proadifen; Tryptamines

1981
Pargyline-induced hepatotoxicity: possible mediation by the reactive metabolite, propiolaldehyde.
    Toxicology and applied pharmacology, 1982, Sep-30, Volume: 65, Issue:3

    Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Pargyline; Proadifen; Rats; Rats, Inbred Strains

1982
Microsomal N-depropargylation of pargyline to propiolaldehyde, an irreversible inhibitor of mitochondrial aldehyde dehydrogenase.
    Advances in experimental medicine and biology, 1980, Volume: 132

    Topics: Aldehyde Oxidoreductases; Aldehydes; Animals; Biotransformation; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoenzymes; Kinetics; Male; Microsomes, Liver; Mitochondria, Liver; Pargyline; Phenobarbital; Proadifen; Rats

1980