pargyline and plomestane

pargyline has been researched along with plomestane in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (52.00)	18.7374
1990's	12 (48.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
di Salle, E; Giudici, D; Ornati, G; Panzeri, A; Zaccheo, T	1
Johnston, JO; Leeson, GA; Wright, CL	1
Gomez-Sanchez, CE; Gomez-Sanchez, EP	1
Doody, KM; Mason, JI; Murry, BA	1
Griffing, GT; Holbrook, M; Johnston, ON; Melby, JC	1
Brandt, ME; Brodie, AM; Melner, MH; Puett, D; Zimniski, SJ	1
Benson, HD; Holbert, GW; Johnston, JO; Wright, CL	1
Brandt, ME; Covey, DF; Zimniski, SJ	1
Briatico, G; di Salle, E; Giudici, D; Ornati, G	1
Briatico, G; di Salle, E; Giudici, D; Ornati, G; Zaccheo, T	1
Alberta, J; Griffing, GT; Holbrook, M; Melby, JC; Orme-Johnson, NR	1
Johnston, JO; Shumaker, RC; Wright, CL	1
Brandt, ME; Covey, DF; Fendl, K; Garola, R; Puett, D; Zimniski, SJ	1
Femino, A; Johnston, JO; Longcope, C	1
Brandt, ME; Covey, DF; Puett, D; Zimniski, SJ	2
Berkovitz, GD; Brown, TR; Kruter, RH; Migeon, CJ	1
Griffing, GT; Holbrook, M; Johnston, JO; Melby, JC	1
Brandt, ME; Covey, DF; Melner, MH; Puett, D; Zimniski, SJ	1
Johnston, JO; Metcalf, BW; Wright, CL	2
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR	1
Covey, DF; Davis, SP; Killinger, DW; Perel, E	1
Holbert, GW; Johnston, JO; Wright, CL	1
Brodie, AM	1

Reviews

2 review(s) available for pargyline and plomestane

Article	Year
Aromatase and aromatase inhibitors: from enzymology to selective chemotherapy. Progress in clinical and biological research, 1988, Volume: 262 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Pargyline; Rats	1988
Aromatase, its inhibitors and their use in breast cancer treatment. Pharmacology & therapeutics, 1993, Volume: 60, Issue:3 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Half-Life; Humans; Neoplasms, Hormone-Dependent; Pargyline	1993

Trials

1 trial(s) available for pargyline and plomestane

Article	Year
Enzyme-activated inhibitors of steroidal hydroxylases. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:1 Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Aromatase Inhibitors; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Drug Tolerance; Estrogens; Humans; Male; Mineralocorticoids; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Zona Glomerulosa	1995

Article

Year

Enzyme-activated inhibitors of steroidal hydroxylases.

The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:1

Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Aromatase Inhibitors; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Drug Tolerance; Estrogens; Humans; Male; Mineralocorticoids; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Zona Glomerulosa

1995

Other Studies

22 other study(ies) available for pargyline and plomestane

Article	Year
Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:9 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Dose-Response Relationship, Drug; Endocrine Glands; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Pargyline; Prolactin; Rats	1991
Regioselectivity of metabolic activation of acetylenic steroids by hepatic cytochrome P450 isozymes. Steroids, 1991, Volume: 56, Issue:4 Topics: Androstenedione; Animals; Aromatase Inhibitors; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Isoenzymes; Liver; Male; Norethindrone; Pargyline; Pentobarbital; Rats; Rats, Inbred Strains; Sleep	1991
The effect of gonadectomy and aromatase inhibition on the excretion of 19-nordeoxycorticosterone in rats. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2 Topics: Androstenedione; Animals; Aromatase Inhibitors; Castration; Desoxycorticosterone; Estrogens; Female; Gonads; Male; Pargyline; Rats; Testosterone	1991
The use of rat Leydig tumor (R2C) and human hepatoma (HEPG2) cells to evaluate potential inhibitors of rat and human steroid aromatase. Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma, Hepatocellular; Cell Line; Drug Screening Assays, Antitumor; Humans; Kinetics; Leydig Cell Tumor; Liver Neoplasms; Male; Pargyline; Rats; Testicular Neoplasms	1990
Antihypertensive effects of an aromatase inhibitor in inbred salt-sensitive rats. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1 Topics: Aldosterone; Androstenedione; Animals; Antihypertensive Agents; Aromatase Inhibitors; Cortisone; Desoxycorticosterone; Female; Hypertension; Male; Pargyline; Rats; Rats, Inbred Strains; Sodium Chloride	1991
Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis. Cancer research, 1991, Jul-15, Volume: 51, Issue:14 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Pargyline; Pregnenolone; Progesterone; Testosterone	1991
Enzyme inactivation by potential metabolites of an aromatase-activated inhibitor (MDL 18,962). Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Biotransformation; Female; Humans; Indicators and Reagents; Kinetics; Microsomes; Pargyline; Placenta; Structure-Activity Relationship	1990
The effects of in vivo administration of 10-propargylestr-4-ene-3,17-dione on rat ovarian aromatase and estrogen levels. Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Estradiol; Estrogens; Estrus; Female; Injections, Subcutaneous; Kinetics; Ovary; Pargyline; Proestrus; Rats; Reference Values	1990
Novel irreversible aromatase inhibitors. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; In Vitro Techniques; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Rats; Rats, Inbred Strains	1990
Aromatase inhibition and experimental antitumor activity of FCE 24304, MDL 18962 and SH 489. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Female; Humans; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Microsomes; Orchiectomy; Ovary; Pargyline; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Reference Values	1989
19-Hydroxylase inhibition of adrenal mitochondrial P450 11 beta/18/19-hydroxylase by a suicide inhibitor. The American journal of the medical sciences, 1989, Volume: 298, Issue:2 Topics: Adrenal Glands; Adrenodoxin; Androstenedione; Animals; Cattle; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Ferredoxin-NADP Reductase; Hydroxylation; In Vitro Techniques; Mitochondria; Pargyline; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases	1989
Human trophoblast xenografts in athymic mice: a model for peripheral aromatization. Journal of steroid biochemistry, 1989, Volume: 33, Issue:4A Topics: Androstenedione; Animals; Aromatase Inhibitors; Choriocarcinoma; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovary; Pargyline; Pregnancy; Tissue Distribution; Tumor Cells, Cultured	1989
Inhibition of peripheral aromatization in baboons by an enzyme-activated aromatase inhibitor (MDL 18,962). Endocrinology, 1988, Volume: 122, Issue:5 Topics: Androstenedione; Animals; Aromatase Inhibitors; Carbon Radioisotopes; Estradiol; Estrone; Female; Kinetics; Metabolic Clearance Rate; Papio; Pargyline; Reference Values; Testosterone; Tritium	1988
Characterization of pregnant mare's serum gonadotropin-stimulated rat ovarian aromatase and its inhibition by 10-propargylestr-4-ene-3,17-dione. Journal of steroid biochemistry, 1988, Volume: 31, Issue:3 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Pregnancy; Rats; Reference Values	1988
Effects of 10-(2-propynyl)-estr-4-ene-3,17-dione (MDL 18,962)--a mechanism-based irreversible inhibitor of aromatase--in cultured human foreskin fibroblasts. Journal of steroid biochemistry, 1987, Volume: 28, Issue:2 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstenedione; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Fibroblasts; Humans; Infant, Newborn; Male; Pargyline; Penis; Receptors, Androgen; Skin	1987
Antihypertensive effects of an aromatase inhibitor in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Topics: Aging; Androstenedione; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Pargyline; Rats; Rats, Inbred SHR	1987
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor. Cancer research, 1985, Volume: 45, Issue:10 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Pargyline; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone	1985
Time-dependent inhibition of aromatase in trophoblastic tumor cells in tissue culture. Journal of steroid biochemistry, 1984, Volume: 20, Issue:6A Topics: Androstenedione; Aromatase Inhibitors; Cell Line; Choriocarcinoma; Estrogens; Female; Humans; Kinetics; Oxidoreductases; Pargyline; Pregnancy; Uterine Neoplasms	1984
Biochemical and endocrine properties of a mechanism-based inhibitor of aromatase. Endocrinology, 1984, Volume: 115, Issue:2 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Biomechanical Phenomena; Chemical Phenomena; Chemistry; Endocrine Glands; Enzyme Inhibitors; Female; Humans; Male; Mice; Mice, Inbred Strains; Ovary; Oxidoreductases; Pargyline; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1984
Comparative studies of aromatase inhibitors in cultured human breast cancer cells. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone	1982
Effects of 4-hydroxy-4-androstene-3, 17-dione and 10-propargylestr-4-ene-3, 17-dione on the metabolism of androstenedione in human breast carcinoma and breast adipose tissues. Steroids, 1981, Volume: 38, Issue:4 Topics: Adipose Tissue; Androstenedione; Breast; Breast Neoplasms; Female; Humans; Kinetics; Pargyline	1981
Inhibition of growth and appearance of estrogen-dependent rat mammary tumors by 10-propargylestr-4-ene-3,17-dione, an aromatase inhibitor. Breast cancer research and treatment, 1993, Volume: 26, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pargyline; Rats; Rats, Sprague-Dawley	1993