pargyline and ascorbic acid

pargyline has been researched along with ascorbic acid in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's6 (21.43)18.2507
2000's2 (7.14)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bai, R; Chen, Y; Gu, J; Han, J; Su, J; Xie, Y; Yang, K; Yu, S; Yuan, S; Zhang, C; Zhou, T1
Bjur, RA; Weiner, N1
Abraini, JH; Fechtali, T; Rostain, JC1
Engel, JA; Hulthe, P; Johannessen, K; Svensson, L; Wu, C1
Debler, EA; Hashim, A; Lajtha, A; Reith, ME; Sershen, H1
Joseph, MH; Young, AM1
Ishitani, R; Karasawa, A; Serikyaku, S1
Gonon, FG; Mermet, CC1
Damm, H; Rommelspacher, H; Susilo, R1
Blaha, CD; Hari, SP; Lane, RF1
Alivisatos, SG; Callaghan, OH; Levitt, LP; Tabakoff, B; Ungar, F1
Aunis, D; Mandel, P; Miras-Portugal, MT1
Stein, L1
Halls, JJ; Karavolas, HJ; Krause, JE1
Blaha, CD; Lane, RF1
Forni, C; Nieoullon, A1
Echizen, H; Freed, CR1
Adams, RN; Miller, E; Rice, ME; Schenk, JO1
Arold, N; Weiner, N; Wesemann, W1
Chiueh, CC; Huang, SJ; Murphy, DL1
Cohen, G; Han, SK; Heinonen, EH; Leonardi, EK; Mytilineou, C; Olanow, CW; Radcliffe, P; Werner, P1
Sears, ML1
Asada, K; Kawano, T; Miyake, C; Morimitsu, Y; Muto, S; Pinontoan, R; Uozumi, N1
Edmondson, DE; Upadhyay, AK; Wang, J1
Akaike, A; Izumi, Y; Kume, T; Matsuo, T; Sawada, H; Takada-Takatori, Y; Wakita, S1
Chen, G; Gao, S; Lin, Z; Liu, Q; Qiu, B; Qiu, S1

Reviews

1 review(s) available for pargyline and ascorbic acid

ArticleYear
Neurochemistry of reward and punishment: some implications for the etiology of schizophrenia.
    Journal of psychiatric research, 1971, Volume: 8, Issue:3

    Topics: Animals; Ascorbic Acid; Bipolar Disorder; Brain; Dopamine; Feeding Behavior; Humans; Hypothalamus; Milk; Mixed Function Oxygenases; Norepinephrine; Pargyline; Phenethylamines; Phenothiazines; Propranolol; Punishment; Rats; Reward; Schizophrenia

1971

Other Studies

27 other study(ies) available for pargyline and ascorbic acid

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Alzheimer Disease; Animals; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrogen Peroxide; Iron Chelating Agents; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridines; Scopolamine; Structure-Activity Relationship

2019
The activity of tyrosine hydroxylase in intact adrenergic neurons of the mouse vas deferens.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:1

    Topics: Animals; Ascorbic Acid; Biological Assay; Biopterins; Carbon Radioisotopes; Catecholamines; Catechols; Kinetics; Male; Mercaptoethanol; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Pargyline; Sympathetic Nervous System; Tritium; Tyrosine; Tyrosine 3-Monooxygenase; Vas Deferens

1975
Pressure reversed extracellular striatal dopamine decrease produced by D1 receptor agonist SKF 38393, and D2 receptor agonist LY 171555, but failed to change the effect of the activation of both D1 and D2 receptors.
    Neuroscience, 1992, Volume: 50, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Apomorphine; Ascorbic Acid; Cerebral Ventricles; Corpus Striatum; Dopamine; Dopamine Agents; Electroencephalography; Ergolines; Homovanillic Acid; Injections, Intraventricular; Kinetics; Male; Methyltyrosines; Pargyline; Pressure; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synapses; Uric Acid

1992
Rapid changes in ascorbate and dopamine release in rat nucleus accumbens after intracerebroventricular administration of NMDA.
    Brain research, 1992, Jul-24, Volume: 586, Issue:2

    Topics: Animals; Anticonvulsants; Ascorbic Acid; Atropine; Cerebral Ventricles; Dopamine; Injections, Intraventricular; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nucleus Accumbens; Pargyline; Picrotoxin; Piperazines; Rats; Rats, Inbred Strains; Time Factors

1992
Carrier-mediated efflux of [3H]dopamine and [3H]1-methyl-4-phenylpyridine: effect of ascorbic acid.
    Synapse (New York, N.Y.), 1991, Volume: 7, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Ascorbic Acid; Corpus Striatum; Diffusion; Dopamine; In Vitro Techniques; Kinetics; Mice; Mice, Inbred BALB C; Monoamine Oxidase; Pargyline; Reserpine; Synaptosomes

1991
Pharmacological evidence, using in vivo dialysis, that substances additional to ascorbic acid, uric acid and homovanillic acid contribute to the voltammetric signals obtained in unrestrained rats from chronically implanted carbon paste electrodes.
    Journal of neuroscience methods, 1991, Volume: 36, Issue:2-3

    Topics: Allopurinol; Animals; Ascorbic Acid; Carbon; Chromatography, High Pressure Liquid; Dialysis; Electrodes, Implanted; Electrophysiology; Extracellular Space; Homovanillic Acid; Male; Pargyline; Rats; Rats, Inbred Strains; Uric Acid

1991
Temperature-sensitive high affinity [3H]tryptamine binding sites in rat brain.
    Life sciences, 1986, Apr-07, Volume: 38, Issue:14

    Topics: Animals; Ascorbic Acid; Brain; Cations; Glutaral; Kinetics; Magnesium; Male; Pargyline; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synaptic Membranes; Temperature; Tryptamines

1986
Ether stress stimulates noradrenaline release in the hypothalamic paraventricular nucleus.
    Neuroendocrinology, 1988, Volume: 47, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Electric Stimulation; Electrochemistry; Ether; Male; Medulla Oblongata; Motor Activity; Neural Pathways; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pargyline; Rats; Rats, Inbred Strains; Stress, Physiological

1988
Formation of a new biogenic aldehyde adduct by incubation of tryptamine with rat brain tissue.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Acetaldehyde; Aldehydes; Animals; Ascorbic Acid; Brain; Chromatography, High Pressure Liquid; Ethanol; Female; Hydrogen-Ion Concentration; Indoleacetic Acids; Indoles; Liver; Mass Spectrometry; Octoxynol; Pargyline; Phospholipids; Polidocanol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Tryptamines

1988
Electrochemistry in vivo: monitoring dopamine release in the brain of the conscious, freely moving rat.
    Brain research bulletin, 1987, Volume: 19, Issue:1

    Topics: Animals; Ascorbic Acid; Corpus Striatum; Dextroamphetamine; Dopamine; Electrochemistry; Electrodes; Graphite; Haloperidol; Male; Pargyline; Pergolide; Rats; Rats, Inbred Strains; Time Factors

1987
Inhibition of the formation of tetrahydroisoquinoline alkaloids in brain homogenates.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:1

    Topics: Alkaloids; Animals; Ascorbic Acid; Brain; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Depression, Chemical; Dopamine; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Isoquinolines; Monoamine Oxidase; Pargyline; Rats; Spectrophotometry, Ultraviolet

1973
Inhibition of adrenal dopamine-beta-hydroxylase by 6-hydroxy dopamine.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Adrenal Medulla; Animals; Ascorbic Acid; Catalase; Cattle; Chromaffin System; Depression, Chemical; Dopamine beta-Hydroxylase; Drug Interactions; Hydrogen Peroxide; Hydroxydopamines; In Vitro Techniques; Iproniazid; Kinetics; Liver; Molecular Weight; Oxidation-Reduction; Pargyline; Proteins; Serum Albumin, Bovine; Time Factors; Tyramine

1973
The effects of neurotransmitters and other cellular modulators and factors on hypothalamic and anterior pituitary delta 4-steroid (progesterone) 5 alpha-reductase activity.
    Steroids, 1980, Volume: 36, Issue:3

    Topics: 20-alpha-Dihydroprogesterone; 3-Hydroxysteroid Dehydrogenases; Animals; Ascorbic Acid; Bacitracin; Dopamine; Edetic Acid; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Middle; Neurotransmitter Agents; Pargyline; Pituitary Gland, Anterior; Progesterone Reductase; Rats; Serotonin; Serotonin Antagonists

1980
Direct in vivo electrochemical monitoring of dopamine release in response to neuroleptic drugs.
    European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Ascorbic Acid; Brain; Chlorpromazine; Dopamine; Electrochemistry; Extracellular Space; Haloperidol; Hydroxydopamines; Male; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains

1984
Electrochemical detection of dopamine release in the striatum of freely moving hamsters.
    Brain research, 1984, Apr-09, Volume: 297, Issue:1

    Topics: Animals; Ascorbic Acid; Corpus Striatum; Cricetinae; Dextroamphetamine; Dopamine; Electrochemistry; Hydroxydopamines; Neural Pathways; Oxidopamine; Pargyline; Substantia Nigra; Tyrosine 3-Monooxygenase

1984
In vivo electrochemical detection of extraneuronal 5-hydroxyindole acetic acid and norepinephrine in the dorsal raphe nucleus of urethane-anesthetized rats.
    Brain research, 1983, Oct-24, Volume: 277, Issue:1

    Topics: Animals; Ascorbic Acid; Brain Stem; Dopamine; Electrochemistry; Extracellular Space; Hydroxyindoleacetic Acid; Male; Norepinephrine; Pargyline; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin

1983
Chronoamperometry in brain slices: quantitative evaluations of in vivo electrochemistry.
    Brain research, 1983, Oct-24, Volume: 277, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Biogenic Amines; Brain Mapping; Caudate Nucleus; Electrochemistry; In Vitro Techniques; Male; Oxidation-Reduction; Pargyline; Rats; Rats, Inbred Strains; Stereotaxic Techniques

1983
Possible hazards in serotonin binding assays in human and rat brain: effects of ascorbate, pargyline, and buffer concentration.
    Journal of neuroscience methods, 1982, Volume: 5, Issue:1-2

    Topics: Animals; Ascorbic Acid; Brain; Buffers; Dose-Response Relationship, Drug; Humans; Pargyline; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin

1982
Suppression of hydroxyl radical formation by MAO inhibitors: a novel possible neuroprotective mechanism in dopaminergic neurotoxicity.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Ascorbic Acid; Clorgyline; Dopamine; Dopamine Agents; Dopamine Antagonists; Hydroxyl Radical; Melanins; Monoamine Oxidase Inhibitors; Nervous System; Oxidation-Reduction; Pargyline; Selegiline

1994
Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:2

    Topics: Amphetamines; Animals; Ascorbic Acid; Buthionine Sulfoximine; Cells, Cultured; Dose-Response Relationship, Drug; Glutathione; Mazindol; Mesencephalon; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Pargyline; Rats; Selegiline; Tyrosine 3-Monooxygenase

1998
Adrenergic supersensitivity of the scorbutic iris.
    Transactions of the American Ophthalmological Society, 1973, Volume: 71

    Topics: Administration, Topical; Adrenergic Agonists; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Cocaine; Dose-Response Relationship, Drug; Epinephrine; Ganglia, Sympathetic; Ganglionectomy; Guinea Pigs; Humans; Injections, Intravenous; Iris; Male; Monoamine Oxidase Inhibitors; Pargyline; Pupil; Receptors, Adrenergic

1973
Phenylethylamine-induced generation of reactive oxygen species and ascorbate free radicals in tobacco suspension culture: mechanism for oxidative burst mediating Ca2+ influx.
    Plant & cell physiology, 2000, Volume: 41, Issue:11

    Topics: Amines; Ascorbic Acid; Calcium; Catalase; Clorgyline; Dehydroascorbic Acid; Dose-Response Relationship, Drug; Free Radicals; Hydrogen Peroxide; Luminol; Monoamine Oxidase Inhibitors; Nicotiana; Onium Compounds; Oxidation-Reduction; Pargyline; Phenethylamines; Plants, Toxic; Reactive Oxygen Species; Salicylamides; Superoxide Dismutase

2000
Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.
    Biochemistry, 2008, Jan-15, Volume: 47, Issue:2

    Topics: Animals; Ascorbic Acid; Binding Sites; Clorgyline; Detergents; Edetic Acid; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Mitochondrial Membranes; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidation-Reduction; Pargyline; Rats; Solubility; Solvents; Spin Labels

2008
Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: Implication of inhibition of vesicular transport.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Aripiprazole; Ascorbic Acid; Biological Transport; Dopamine; Extracellular Space; Gene Expression Regulation, Enzymologic; Haloperidol; Homovanillic Acid; Mesencephalon; Neurons; Pargyline; PC12 Cells; Pimozide; Piperazines; Quinolones; Rats; Spiperone; Transport Vesicles; Tyrosine 3-Monooxygenase

2010
Electrochemical impedance spectroscopy sensor for ascorbic acid based on copper(I) catalyzed click chemistry.
    Biosensors & bioelectronics, 2011, Jul-15, Volume: 26, Issue:11

    Topics: Alkynes; Ascorbic Acid; Azides; Biosensing Techniques; Catalysis; Click Chemistry; Copper; Dielectric Spectroscopy; Ferrous Compounds; Gold; Humans; Metallocenes; Oxidation-Reduction; Pargyline; Propylamines

2011