Page last updated: 2024-09-03

parecoxib and morphine

parecoxib has been researched along with morphine in 52 studies

Compound Research Comparison

Studies
(parecoxib)
Trials
(parecoxib)
Recent Studies (post-2010)
(parecoxib)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
43618622944,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyparecoxib (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (42.31)29.6817
2010's22 (42.31)24.3611
2020's8 (15.38)2.80

Authors

AuthorsStudies
Hogue, C; Hubbard, RC; Rasmussen, GL; Steckner, K; Torri, S1
Barton, SF; Dhadda, SS; Hubbard, RC; Kuss, ME; Langeland, FF; LeComte, D; Snabes, MC1
Chen, X; Kariger, R; Li, S; Naruse, R; Norel, E; Quon, R; Sloninsky, A; Tang, J; Webb, T; Wender, RH; White, PF1
Dhadda, S; Hubbard, RC; Naumann, TM; Traylor, L1
Grossman, E; Hakki, SI; Hubbard, RC; Malan, TP; Marsh, G; Traylor, L1
Davidson, AC; Ng, A; Smith, G1
Alston, RP; Duke, PC; Feneck, RO; Hsu, PH; Hubbard, RC; Mangano, DT; Nussmeier, NA; Ott, E; Saidman, LJ; Snabes, MC1
Katz, N1
Chen, C; Cleeland, CS; Hanna, DB; Jensen, MP; Mendoza, T1
Bajwa, ZH; Bikhazi, GB; Davis, DJ; Hubbard, RC; LeComte, D; Snabes, MC; Traylor, L1
Gordon, S; Hubbard, R; Malan, TP; Snabes, M1
Baechle, JP; Beaussier, M; Buffin, A; Didelot, JP; Goater, P; Lavazais, S; Lienhart, A; Loriferne, JF; Mosbah, A; Paugam, C; Perier, JF; Said, R; Weickmans, H1
Chaterjee, A; Khalil, MW; Macbryde, G; Marks, RR; Sarkar, PK1
Boye, ME; Brown, MT; Joshi, GP; Langford, RM; Nussmeier, NA; Singla, NK; Verburg, KM; Whelton, AA1
Abdalla, H; Buckley, E; Butler, M; Iohom, G; Larney, V; O'Brien, J; Shorten, GD; Szarvas, S1
Beaussier, M; Lienhart, A; Sean, PT; Tilleul, P; Weickmans, H1
Bunburaphong, P; Niruthisard, S; Toleb, K; Ussawanophakiat, M; Werawataganon, T; Wongsakornchaikul, C1
Bello, A; Dreyer, S; Eikermann, M; Klassen, PD; Peters, J; Riest, G; Stegen, B; Weiss, M1
Foocharoen, T; Jirarattanaphochai, K; Jung, S; Lertsinudom, S; Pulnitiporn, A; Sriraj, W; Thienthong, S1
Cormack, J; Jones, SJ; Murphy, MA; Scott, DA1
Chambers, P; Johnson, CB; Kongara, K1
Chambers, JP; Johnson, CB; Kongara, K1
Tanavalee, A; Thiengwittayaporn, S1
Dervenis, C; Kapota, E; Kostopanagiotou, G; Matsota, P; Pandazi, A; Paraskevopoulou, P1
Cheu, NW; Chuang, FH; Liao, CH; Tan, TD; Wang, YR; Watts, MP; Wong, JO1
Gu, MN; Hou, XM; Liu, GW; Liu, XJ; Xiao, JF1
Leslie, K; Pemberton, E; Williams, DL1
Bao, Y; Fang, J; Li, W; Liu, K; Luo, H; Peng, L; Yi, Y1
Díaz-Ponce, H; Galindo-Suárez, RM; Muciño-Ortega, E; Walter-Tordecillas, MA1
Wang, S; Wu, H; Wu, Y; Zhu, Y1
Li, H; Nong, L; Sun, Y; Tian, Y1
Ba, YF; He, SH; Li, CS; Li, XD; Li, Y; Liu, YN; Ning, ZH; Wang, QH; Zhang, H; Zhang, X; Zhu, Y1
Chang, PY; Chen, YC; Cheng, KI; Hsu, HT; Huang, HF; Lu, IC; Tseng, KY1
Dirkmann, D; Eikermann, M; Farhan, H; Groeben, H; Stahl, DL1
Li, J; Li, N; Peng, N; Yang, X1
Chen, CL; Cheng, KW; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Liu, CK; Shih, TH; Wang, CH; Wu, SC; Yang, SC1
Huang, WQ; Liu, KX; Liu, WF; Peng, SL; Shu, HH; Xiao, JF; Zhang, GR; Zhao, GD1
Borgeat, A; Boye, ME; Camu, F; Cheung, RY; Heylen, RJ; Viel, EJ1
Li, CJ; Li, XY; Li, YW; Liu, C; Meng, ZT; Mu, DL; Wang, DX; Wang, G; Zhang, DZ1
Pei, F; Shen, B; Si, H; Weng, X; Wu, Y; Yang, T; Zeng, Y1
Bian, YY; Jin, J; Lin, J; Peng, HM; Qian, WW; Wang, LC; Weng, XS1
Chang, CC; Chen, CY; Liao, YM; Lin, PC; Lin, YC1
Bian, Y; Peng, H; Weng, X; Wu, Z; Xiao, K; Xiao, W; Yu, L1
Ben Fadhel, K; Bousselmi, J; Haddad, F; Jaoua, H; Mrabet, A1
Borgeat, A; Camu, F; Cheung, R; Essex, MN; Pan, S; Salomon, PA1
Chinwatanawongwan, B; Chompoonutprapa, P; Laoruengthana, A; Pongpirul, K; Rattanaprichavej, P; Reosanguanwong, K1
Cao, S; Hu, J; Li, Y; Liu, F; Liu, Q; Xiong, Z; Zhang, X; Zhou, L1
Chen, CF; Chen, WM; Chou, TA; Ma, HH; Tsai, SW; Wang, HY; Wu, PK1
Chen, Y; Liu, G; Ma, Y; Tian, X; Yang, Y; Zhuang, Y1
Chaibhuddanugul, N; Laoruengthana, A; Malisorn, S; Pongpirul, K; Rattanaprichavej, P; Tangsripong, P1
Angthong, C; Manuwong, S; Rajbhandari, P; Singh, V; Veljkovic, A1
Ge, WK; Hong, C; Lin, SN; Liu, CJ; Xie, HY; Yu, M1

Reviews

2 review(s) available for parecoxib and morphine

ArticleYear
Pain Relief by Parecoxib for Laparoscopic Cholecystectomy: A Meta-Analysis of Randomized Controlled Trials.
    Asian journal of anesthesiology, 2018, Volume: 56, Issue:3

    Topics: Cholecystectomy, Laparoscopic; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Morphine; Pain Measurement; Pain, Postoperative; Publication Bias; Randomized Controlled Trials as Topic

2018
The efficacy of parecoxib in improving pain after total knee or total hip arthroplasty: Systematic review and meta-analysis.
    Medicine, 2022, Sep-23, Volume: 101, Issue:38

    Topics: Aged; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Morphine; Nausea; Pain, Postoperative; Vomiting

2022

Trials

44 trial(s) available for parecoxib and morphine

ArticleYear
Intravenous parecoxib sodium foracute pain after orthopedic knee surgery.
    American journal of orthopedics (Belle Mead, N.J.), 2002, Volume: 31, Issue:6

    Topics: Aged; Analgesia; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Isoxazoles; Ketorolac; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Sensitivity and Specificity; Treatment Outcome

2002
Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery.
    Anesthesiology, 2002, Volume: 97, Issue:2

    Topics: Adult; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Hysterectomy; Injections, Intravenous; Isoxazoles; Ketorolac; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

2002
Effect of parecoxib, a novel intravenous cyclooxygenase type-2 inhibitor, on the postoperative opioid requirement and quality of pain control.
    Anesthesiology, 2002, Volume: 96, Issue:6

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Isoxazoles; Middle Aged; Morphine; Pain, Postoperative

2002
Parecoxib sodium has opioid-sparing effects in patients undergoing total knee arthroplasty under spinal anaesthesia.
    British journal of anaesthesia, 2003, Volume: 90, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anesthesia, Spinal; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Patient Satisfaction

2003
Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty.
    Anesthesiology, 2003, Volume: 98, Issue:4

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases

2003
Analgesic effects of parecoxib following total abdominal hysterectomy.
    British journal of anaesthesia, 2003, Volume: 90, Issue:6

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hysterectomy; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting

2003
Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:6

    Topics: Administration, Oral; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Coronary Artery Bypass; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Isoenzymes; Isoxazoles; Male; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Safety; Sulfonamides

2003
The analgesic effects that underlie patient satisfaction with treatment.
    Pain, 2004, Volume: 110, Issue:1-2

    Topics: Adult; Analgesics; Cholecystectomy, Laparoscopic; Double-Blind Method; Drug Administration Routes; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Outcome Assessment, Health Care; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Preoperative Care; Prospective Studies; Retrospective Studies; Sex Factors; Sulfonamides; Time Factors

2004
A clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:4

    Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Hysterectomy; Isoxazoles; Ketorolac; Laparotomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

2004
The cyclooxygenase-2-specific inhibitor parecoxib sodium is as effective as 12 mg of morphine administered intramuscularly for treating pain after gynecologic laparotomy surgery.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:2

    Topics: Adult; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Injections, Intramuscular; Isoxazoles; Laparoscopy; Membrane Proteins; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases

2005
A randomized, double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:5

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Hernia, Inguinal; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies

2005
Single dose parecoxib significantly improves ventilatory function in early extubation coronary artery bypass surgery: a prospective randomized double blind placebo controlled trial.
    British journal of anaesthesia, 2006, Volume: 96, Issue:2

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Coronary Artery Bypass; Creatinine; Cyclooxygenase 2 Inhibitors; Device Removal; Double-Blind Method; Drug Administration Schedule; Fluid Therapy; Humans; Intubation, Intratracheal; Isoxazoles; Kidney; Middle Aged; Morphine; Pain, Postoperative; Postoperative Care; Respiration

2006
Safety and efficacy of the cyclooxygenase-2 inhibitors parecoxib and valdecoxib after noncardiac surgery.
    Anesthesiology, 2006, Volume: 104, Issue:3

    Topics: Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Sulfonamides

2006
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Disease; Depression; Dextropropoxyphene; Diclofenac; Female; Humans; Isoxazoles; Mastectomy; Middle Aged; Morphine; Nerve Block; Nitric Oxide; Nociceptors; Pain Measurement; Pain, Postoperative; Pyrazoles; Sulfonamides

2006
Cost analysis applied to postoperative analgesia regimens: a comparison between parecoxib and propacetamol.
    Pharmacy world & science : PWS, 2007, Volume: 29, Issue:4

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Hernia, Inguinal; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Patient Satisfaction; Prospective Studies

2007
Improving the analgesic efficacy of intrathecal morphine with parecoxib after total abdominal hysterectomy.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:3

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hysterectomy; Injections, Intravenous; Injections, Spinal; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Treatment Outcome

2007
Preventive effects of perioperative parecoxib on post-discectomy pain.
    British journal of anaesthesia, 2008, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase Inhibitors; Diskectomy; Double-Blind Method; Drug Administration Schedule; Humans; Isoxazoles; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Perioperative Care; Postoperative Care; Preanesthetic Medication; Prospective Studies

2008
Effect of parecoxib on postoperative pain after lumbar spine surgery: a bicenter, randomized, double-blinded, placebo-controlled trial.
    Spine, 2008, Jan-15, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Decompression, Surgical; Diskectomy; Drug Therapy, Combination; Humans; Isoxazoles; Lumbar Vertebrae; Middle Aged; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Spinal Fusion; Treatment Outcome

2008
Parecoxib for analgesia after craniotomy.
    British journal of anaesthesia, 2009, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Craniotomy; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Young Adult

2009
Glomerular filtration rate after tramadol, parecoxib and pindolol following anaesthesia and analgesia in comparison with morphine in dogs.
    Veterinary anaesthesia and analgesia, 2009, Volume: 36, Issue:1

    Topics: Analgesics; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Dogs; Glomerular Filtration Rate; Isoxazoles; Morphine; Pindolol; Tramadol

2009
Preincisional versus postincisional administration of parecoxib in colorectal surgery: effect on postoperative pain control and cytokine response. A randomized clinical trial.
    World journal of surgery, 2010, Volume: 34, Issue:10

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Colectomy; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Cytokines; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative

2010
Comparison of the efficacy of parecoxib versus ketorolac combined with morphine on patient-controlled analgesia for post-cesarean delivery pain management.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2010, Volume: 48, Issue:4

    Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Cesarean Section; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Infusions, Intravenous; Isoxazoles; Ketorolac; Morphine; Pain, Postoperative; Pregnancy

2010
[Effects of parecoxib on morphine dosage in postoperative patient-controlled analgesia following thoracoscope-assisted thoracotomy].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:2

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Combined Modality Therapy; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative; Thoracoscopy; Thoracotomy; Young Adult

2011
Effect of intravenous parecoxib on post-craniotomy pain.
    British journal of anaesthesia, 2011, Volume: 107, Issue:3

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Craniotomy; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain, Postoperative

2011
Comparison of preincisional and postincisional parecoxib administration on postoperative pain control and cytokine response after total hip replacement.
    The Journal of international medical research, 2012, Volume: 40, Issue:5

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Cytokines; Female; Femur Head Necrosis; Hip Fractures; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative

2012
Effect of perioperative parecoxib on postoperative pain and local inflammation factors PGE2 and IL-6 for total knee arthroplasty: a randomized, double-blind, placebo-controlled study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014, Volume: 24, Issue:3

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Female; Humans; Inflammation; Interleukin-6; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Range of Motion, Articular; Synovial Fluid

2014
Effects of parecoxib on morphine analgesia after gynecology tumor operation: a randomized trial of parecoxib used in postsurgical pain management.
    The Journal of surgical research, 2013, Volume: 183, Issue:2

    Topics: Adult; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genital Neoplasms, Female; Humans; Isoxazoles; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Treatment Outcome

2013
Comparison of the analgesic effects of cryoanalgesia vs. parecoxib for lung cancer patients after lobectomy.
    Surgery today, 2015, Volume: 45, Issue:10

    Topics: Adult; Aged; Analgesia; Cryoanesthesia; Female; Humans; Intercostal Nerves; Isoxazoles; Lung Neoplasms; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Pneumonectomy

2015
Single bolus parecoxib attenuates sore throat after laryngeal microsurgery: a randomized double-blind control study.
    The Kaohsiung journal of medical sciences, 2014, Volume: 30, Issue:11

    Topics: Adult; Female; Humans; Isoxazoles; Larynx; Male; Microsurgery; Middle Aged; Morphine; Patient Satisfaction; Pharyngitis; Postoperative Complications

2014
Effects of parecoxib on analgesia benefit and blood loss following open prostatectomy: a multicentre randomized trial.
    BMC anesthesiology, 2015, Volume: 15

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Hemorrhage; Prostatectomy

2015
Effect of cyclooxygenase-2-specific inhibitors on postoperative analgesia after major open abdominal surgery.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2015, Volume: 16, Issue:3

    Topics: Abdomen; Analgesia, Patient-Controlled; Analgesics, Opioid; Analysis of Variance; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Tramadol

2015
Effect of Parecoxib as an Adjunct to Patient-Controlled Epidural Analgesia after Abdominal Hysterectomy: A Multicenter, Randomized, Placebo-Controlled Trial.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hysterectomy; Isoxazoles; Middle Aged; Morphine; Pain Management; Pain, Postoperative; Ropivacaine; Young Adult

2016
Parecoxib, propacetamol, and their combination for analgesia after total hip arthroplasty: a randomized non-inferiority trial.
    Acta anaesthesiologica Scandinavica, 2017, Volume: 61, Issue:1

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Arthroplasty, Replacement, Hip; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Recovery of Function

2017
Parecoxib Supplementation to Morphine Analgesia Decreases Incidence of Delirium in Elderly Patients After Hip or Knee Replacement Surgery: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:6

    Topics: Administration, Intravenous; Age Factors; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; China; Cyclooxygenase 2 Inhibitors; Delirium; Double-Blind Method; Female; Humans; Incidence; Intention to Treat Analysis; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

2017
[EFFICACY OF SEQUENTIAL TREATMENT WITH ADDUCTOR CANAL NERVE BLOCK AND CYCLOOXYGENASE 2 SELECTIVE INHIBITOR AFTER TOTAL KNEE ARTHROPLASTY].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2016, Sep-08, Volume: 30, Issue:9

    Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Knee Joint; Morphine; Nerve Block; Operative Time; Osteoarthritis; Pain, Postoperative; Postoperative Period; Range of Motion, Articular; Treatment Outcome

2016
Role of Parecoxib Sodium in the Multimodal Analgesia after Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial.
    Orthopaedic surgery, 2018, Volume: 10, Issue:4

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Range of Motion, Articular

2018
Pain Management Using Perioperative Administration of Parecoxib for Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Pain physician, 2019, Volume: 22, Issue:6

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies

2019
Parecoxib in laparoscopic surgery for simple vesicular lithiasis.
    La Tunisie medicale, 2019, Volume: 97, Issue:12

    Topics: Adult; Analgesia; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Combined Modality Therapy; Double-Blind Method; Female; Humans; Isoxazoles; Lithiasis; Male; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Recovery Room; Tunisia; Urinary Bladder Calculi

2019
The relationship between postoperative opioid consumption and the incidence of hypoxemic events following total hip arthroplasty: a post hoc analysis.
    Canadian journal of surgery. Journal canadien de chirurgie, 2020, 05-08, Volume: 63, Issue:3

    Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hypoxia; Incidence; Isoxazoles; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Switzerland; Treatment Outcome

2020
A randomized controlled trial comparing the efficacies of ketorolac and parecoxib for early pain management after total knee arthroplasty.
    The Knee, 2020, Volume: 27, Issue:6

    Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Blood Transfusion; Bupivacaine; Drug Therapy, Combination; Drug Utilization; Female; Humans; Injections, Intra-Articular; Isoxazoles; Ketorolac; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies; Visual Analog Scale

2020
Intraoperative periarticular injection can alleviate the inflammatory response and enhance joint function recovery after hip arthroplasty in elderly patients with osteoporotic femoral neck fractures.
    Medicine, 2021, Feb-19, Volume: 100, Issue:7

    Topics: Aged; Arthroplasty, Replacement, Hip; Betamethasone; Biomarkers; Drug Therapy, Combination; Epinephrine; Female; Femoral Neck Fractures; Humans; Inflammation Mediators; Injections, Intra-Articular; Intraoperative Care; Isoxazoles; Male; Morphine; Osteoporotic Fractures; Postoperative Complications; Recovery of Function; Ropivacaine

2021
An opioid-sparing protocol with intravenous parecoxib can effectively reduce morphine consumption after simultaneous bilateral total knee arthroplasty.
    Scientific reports, 2021, 04-01, Volume: 11, Issue:1

    Topics: Administration, Intravenous; Aged; Arthroplasty, Replacement, Knee; Female; Humans; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities; Postoperative Period; Prospective Studies; Range of Motion, Articular; Treatment Outcome; Visual Analog Scale

2021
Effects of parecoxib after pancreaticoduodenectomy: A single center randomized controlled trial.
    International journal of surgery (London, England), 2021, Volume: 90

    Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Pancreaticoduodenectomy

2021
Efficacy of intravenous perioperative parecoxib administration in the surgical fixation of unstable ankle fracture: a prospective, double-blinded, randomized, placebo-controlled trial.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:14

    Topics: Ankle Fractures; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies

2021

Other Studies

6 other study(ies) available for parecoxib and morphine

ArticleYear
Reporting of clinical trials of analgesia.
    The Journal of thoracic and cardiovascular surgery, 2004, Volume: 127, Issue:2

    Topics: Analgesia; Analgesia, Patient-Controlled; Clinical Trials as Topic; Coronary Artery Bypass; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Morphine; Prostaglandin-Endoperoxide Synthases; Sulfonamides

2004
Electroencephalographic responses of tramadol, parecoxib and morphine to acute noxious electrical stimulation in anaesthetised dogs.
    Research in veterinary science, 2010, Volume: 88, Issue:1

    Topics: Analgesics; Anesthesia; Animals; Cyclooxygenase 2 Inhibitors; Dogs; Dose-Response Relationship, Drug; Drug Evaluation; Electric Stimulation; Electrocardiography; Electroencephalography; Female; Heart Rate; Isoxazoles; Male; Morphine; Narcotics; Tramadol

2010
Multimodal pain management following minimally invasive total knee arthroplasty: an experience in 3-dose parecoxib.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009, Volume: 92 Suppl 6

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Female; Humans; Injections, Intravenous; Isoxazoles; Male; Middle Aged; Minimally Invasive Surgical Procedures; Morphine; Pain Measurement; Pain, Postoperative; Recovery of Function; Treatment Outcome

2009
[Economic analysis of parecoxib in the management of postsurgical pain in gynecology].
    Ginecologia y obstetricia de Mexico, 2012, Volume: 80, Issue:11

    Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Costs and Cost Analysis; Decision Trees; Female; Gynecologic Surgical Procedures; Humans; Isoxazoles; Ketorolac; Morphine; Pain, Postoperative

2012
Transitional Study of Patient-Controlled Analgesia Morphine With Ketorolac to Patient-Controlled Analgesia Morphine With Parecoxib Among Donors in Adult Living Donor Liver Transplantation: A Single-Center Experience.
    Transplantation proceedings, 2016, Volume: 48, Issue:4

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Humans; Isoxazoles; Ketorolac; Liver Transplantation; Living Donors; Male; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies; Tissue and Organ Harvesting

2016
Perioperative Outcomes of Patients Who Were Not Candidates for Additional Nonsteroidal Anti-inflammatory Drugs in a Multimodal Pain Control Regimen for Total Knee Arthroplasty.
    Clinics in orthopedic surgery, 2021, Volume: 13, Issue:2

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Humans; Isoxazoles; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies

2021