parecoxib has been researched along with fentanyl in 7 studies
| Studies (parecoxib) | Trials (parecoxib) | Recent Studies (post-2010) (parecoxib) | Studies (fentanyl) | Trials (fentanyl) | Recent Studies (post-2010) (fentanyl) |
|---|---|---|---|---|---|
| 436 | 186 | 229 | 15,288 | 4,310 | 4,483 |
| Protein | Taxonomy | parecoxib (IC50) | fentanyl (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 6.5 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.6342 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.1888 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0122 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0058 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.3092 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 5.893 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.58 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0031 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.8197 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 4.973 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.354 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feldman, J; Ibrahim, AE; Karim, A; Kharasch, ED | 1 |
| Autio, V; Lindgren, L; Pirhonen, RA; Puolakka, PA; Puura, AI; Ranta, AU; Rorarius, MG | 1 |
| Joshi, C; Prasad, CN; Sharma, A; Subramaniam, R | 1 |
| Anagnostou, T; Gravas, S; Karatzas, A; Melekos, MD; Mitsogiannis, IC; Poulakis, V; Tzortzis, V | 1 |
| Li, XX; Peng, YZ; Wang, YW | 1 |
| Chen, CL; Cheng, KW; Chiu, YC; Huang, CE; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Shih, TH; Wang, CH; Wu, SC; Yang, SC | 1 |
| Cui, Y; Lan, Y; Li, X; Liu, L; Liu, Y; Meng, F; Song, X; Sun, D; Wang, J; Wang, Y; Yang, G; Zhang, B | 1 |
6 trial(s) available for parecoxib and fentanyl
| Article | Year |
|---|---|
Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil.
Topics: Adult; Affect; Alfentanil; Algorithms; Analgesics, Opioid; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Fentanyl; Half-Life; Hemodynamics; Humans; Isoxazoles; Liver; Male; Mass Spectrometry; Oxidoreductases, N-Demethylating; Pupil; Respiratory Mechanics; Troleandomycin | 2003 |
Lack of analgesic effect of parecoxib following laparoscopic cholecystectomy.
Topics: Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Fentanyl; Humans; Isoxazoles; Male; Middle Aged; Pain, Postoperative; Prospective Studies | 2006 |
Analgesic efficacy of single-dose parecoxib for corneal suturing in children.
Topics: Adolescent; Analgesia; Anesthetics, Intravenous; Anesthetics, Local; Child; Cornea; Corneal Injuries; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Synergism; Fentanyl; Humans; Isoxazoles; Pain Measurement; Pain, Postoperative; Propoxycaine; Suture Techniques; Treatment Outcome | 2007 |
Analgesia during extracorporeal shockwave lithotripsy: fentanyl citrate versus parecoxib sodium.
Topics: Adult; Aged; Analgesics, Opioid; Cyclooxygenase Inhibitors; Female; Fentanyl; Humans; Isoxazoles; Lithotripsy; Male; Middle Aged; Pain | 2008 |
Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study.
Topics: Acute Pain; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Drug Therapy, Combination; Female; Fentanyl; Hepatectomy; Humans; Isoxazoles; Liver Cirrhosis; Liver Transplantation; Living Donors; Male; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Retrospective Studies | 2016 |
Evaluation of Intravenous Parecoxib Infusion Pump of Patient-Controlled Analgesia Compared to Fentanyl for Postoperative Pain Management in Laparoscopic Liver Resection.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Hepatectomy; Humans; Infusion Pumps; Infusions, Intravenous; Isoxazoles; Laparoscopy; Liver; Male; Middle Aged; Pain Management; Pain, Postoperative; Prospective Studies | 2018 |
1 other study(ies) available for parecoxib and fentanyl
| Article | Year |
|---|---|
Effects of Parecoxib and Fentanyl on nociception-induced cortical activity.
Topics: Action Potentials; Analgesics, Opioid; Animals; Arousal; Cerebral Cortex; Cyclooxygenase 2 Inhibitors; Electroencephalography; Electrophysiology; Evoked Potentials; Fentanyl; Gyrus Cinguli; Heart Rate; Isoxazoles; Neurons; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Respiration; Somatosensory Cortex | 2010 |