Page last updated: 2024-09-03

parecoxib and aspirin

parecoxib has been researched along with aspirin in 5 studies

Compound Research Comparison

Studies
(parecoxib)
Trials
(parecoxib)
Recent Studies (post-2010)
(parecoxib)
Studies
(aspirin)
Trials
(aspirin)
Recent Studies (post-2010) (aspirin)
43618622948,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomyparecoxib (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A1
Borgdorff, P; Paulus, WJ; Tangelder, GJ1
Herrndobler, F; Koppert, W; Maihöfner, C; Ringler, R1
Bartra, J; Muñoz-Cano, R; Picado, C; Roca, J; Sánchez-López, J; Serrano, C; Valero, A1
Armstrong, PC; Emerson, M; Kirkby, NS; Mitchell, JA; Warner, TD; Zain, ZN1

Trials

3 trial(s) available for parecoxib and aspirin

ArticleYear
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isoenzymes; Isoxazoles; Lysine; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Vasodilation; Vasodilator Agents

2003
[Modulation of cortical pain processing by cyclooxygenase inhibition: a functional MRI study].
    Schmerz (Berlin, Germany), 2009, Volume: 23, Issue:2

    Topics: Acute Disease; Adult; Analgesics; Aspirin; Brain Mapping; Cerebral Cortex; Cyclooxygenase Inhibitors; Dominance, Cerebral; Double-Blind Method; Female; Frontal Lobe; Gyrus Cinguli; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Isoxazoles; Magnetic Resonance Imaging; Male; Motor Cortex; Pain; Pain Measurement; Pain Threshold; Parietal Lobe; Psychophysics; Somatosensory Cortex

2009
Safety of parecoxib in asthmatic patients with aspirin-exacerbated respiratory disease.
    International archives of allergy and immunology, 2011, Volume: 156, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Cyclooxygenase 2 Inhibitors; Female; Forced Expiratory Volume; Humans; Isoxazoles; Leukotriene E4; Male; Middle Aged; Nasal Provocation Tests

2011

Other Studies

2 other study(ies) available for parecoxib and aspirin

ArticleYear
Cyclooxygenase-2 inhibitors enhance shear stress-induced platelet aggregation.
    Journal of the American College of Cardiology, 2006, Aug-15, Volume: 48, Issue:4

    Topics: Animals; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Stenosis; Cyclooxygenase Inhibitors; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Risk Factors; Shear Strength; Thrombosis; Ticlopidine

2006
Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Isoxazoles; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Thrombosis

2011