parecoxib has been researched along with aspirin in 5 studies
| Studies (parecoxib) | Trials (parecoxib) | Recent Studies (post-2010) (parecoxib) | Studies (aspirin) | Trials (aspirin) | Recent Studies (post-2010) (aspirin) |
|---|---|---|---|---|---|
| 436 | 186 | 229 | 48,947 | 6,817 | 13,778 |
| Protein | Taxonomy | parecoxib (IC50) | aspirin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.35 | |
| Integrin beta-3 | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.8252 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 1.375 | |
| Integrin alpha-IIb | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.271 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 2.4 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 2.15 | |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | 0.3 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 2.4 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.35 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4081 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A | 1 |
| Borgdorff, P; Paulus, WJ; Tangelder, GJ | 1 |
| Herrndobler, F; Koppert, W; Maihöfner, C; Ringler, R | 1 |
| Bartra, J; Muñoz-Cano, R; Picado, C; Roca, J; Sánchez-López, J; Serrano, C; Valero, A | 1 |
| Armstrong, PC; Emerson, M; Kirkby, NS; Mitchell, JA; Warner, TD; Zain, ZN | 1 |
3 trial(s) available for parecoxib and aspirin
| Article | Year |
|---|---|
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isoenzymes; Isoxazoles; Lysine; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2003 |
[Modulation of cortical pain processing by cyclooxygenase inhibition: a functional MRI study].
Topics: Acute Disease; Adult; Analgesics; Aspirin; Brain Mapping; Cerebral Cortex; Cyclooxygenase Inhibitors; Dominance, Cerebral; Double-Blind Method; Female; Frontal Lobe; Gyrus Cinguli; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Isoxazoles; Magnetic Resonance Imaging; Male; Motor Cortex; Pain; Pain Measurement; Pain Threshold; Parietal Lobe; Psychophysics; Somatosensory Cortex | 2009 |
Safety of parecoxib in asthmatic patients with aspirin-exacerbated respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Cyclooxygenase 2 Inhibitors; Female; Forced Expiratory Volume; Humans; Isoxazoles; Leukotriene E4; Male; Middle Aged; Nasal Provocation Tests | 2011 |
2 other study(ies) available for parecoxib and aspirin
| Article | Year |
|---|---|
Cyclooxygenase-2 inhibitors enhance shear stress-induced platelet aggregation.
Topics: Animals; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Stenosis; Cyclooxygenase Inhibitors; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Risk Factors; Shear Strength; Thrombosis; Ticlopidine | 2006 |
Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Isoxazoles; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Thrombosis | 2011 |