parecoxib has been researched along with alfentanil in 1 studies
| Studies (parecoxib) | Trials (parecoxib) | Recent Studies (post-2010) (parecoxib) | Studies (alfentanil) | Trials (alfentanil) | Recent Studies (post-2010) (alfentanil) |
|---|---|---|---|---|---|
| 436 | 186 | 229 | 1,731 | 757 | 172 |
| Protein | Taxonomy | parecoxib (IC50) | alfentanil (IC50) |
|---|---|---|---|
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0389 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feldman, J; Ibrahim, AE; Karim, A; Kharasch, ED | 1 |
1 trial(s) available for parecoxib and alfentanil
| Article | Year |
|---|---|
Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil.
Topics: Adult; Affect; Alfentanil; Algorithms; Analgesics, Opioid; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Fentanyl; Half-Life; Hemodynamics; Humans; Isoxazoles; Liver; Male; Mass Spectrometry; Oxidoreductases, N-Demethylating; Pupil; Respiratory Mechanics; Troleandomycin | 2003 |