Page last updated: 2024-08-21

paraquat and metallothionein

paraquat has been researched along with metallothionein in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's10 (38.46)18.2507
2000's9 (34.62)29.6817
2010's5 (19.23)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Bauman, JW; Klaassen, CD; Liu, Y; Madhu, C; McKim, JM1
Imura, N; Naganuma, A; Satoh, M1
Sato, M1
Bauman, JW; Klaassen, CD; Liu, J; Liu, YP1
Sasaki, M; Sato, M1
Mizunuma, H; Nagai, Y; Ohtake, A; Sato, M; Takeda, K1
Hojo, H; Sasaki, M; Sato, M1
Choo, KH; Dellapiazza, D; Kondo, Y; Lazo, JS; Michalska, AE; Pitt, BR1
Bonneton, F; Maroni, G; Silar, P; Théodore, L; Wegnez, M1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M; Yanagiya, T1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M1
Choi, CH; Chung, MH; Jeong, JH; Kim, HS; Kim, MS; Kweon, OS; Lee, TB; Lim, DY; Min, YD; Rha, HS; You, HJ1
Suntres, ZE1
Ruzsa, SM; Scandalios, JG1
Choi, CH1
Higashimoto, M; Imada, N; Kamada, K; Kondoh, M; Sato, M; Takiguchi, M; Tsukahara, R; Watanabe, Y1
Choi, CH; Jeon, HJ; Kim, KC; Kim, KJ; Lee, TB; Lim, DY; Min, YD1
Agar, JN; Durham, HD; Minotti, S; Taylor, DM1
Ishikawa, T; Katsuyama, H; Okuyama, T; Tomita, M1
Balestrazzi, A; Berta, G; Biondi, S; Botti, S; Calligari, P; Carbonera, D; Franchin, C; Lingua, G; Racchi, M; Turchi, A; Zelasco, S1
Ahmad, I; Kumar, A; Pandey, HP; Patel, DK; Shukla, S; Singh, BK; Singh, C1
Blindauer, CA; Bundy, JG; Geier, FM; Leszczyszyn, OI; Stürzenbaum, SR; Zeitoun-Ghandour, S1
Khalaf, H; Kling, P; Modig, C; Mujahed, H; Olsson, PE; von Hofsten, J1
He, J; Peng, SQ; Ren, M; Ren, SP; Wang, YM; Zhang, TF; Zhao, J; Zhao, ZM1
Ahn, KH; Back, MJ; Fu, Z; Ha, HC; Jang, JM; Jang, YJ; Kim, DK; Lim, JH; Won, JH1
Das, S; Mohamad Najib, NH; Teoh, SL; Yahaya, MF1

Reviews

1 review(s) available for paraquat and metallothionein

ArticleYear
Role of antioxidants in paraquat toxicity.
    Toxicology, 2002, Oct-30, Volume: 180, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E

2002

Other Studies

25 other study(ies) available for paraquat and metallothionein

ArticleYear
Induction of hepatic metallothionein by paraquat.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:2

    Topics: Animals; Base Sequence; Bile; Cells, Cultured; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Liver; Male; Metallothionein; Mice; Molecular Sequence Data; Paraquat; Potassium; RNA, Messenger; Time Factors; Zinc

1992
Effect of preinduction of metallothionein on paraquat toxicity in mice.
    Archives of toxicology, 1992, Volume: 66, Issue:2

    Topics: Animals; Enzyme Induction; Free Radical Scavengers; Lipid Peroxidation; Lung; Male; Metallothionein; Metals; Mice; Mice, Inbred ICR; Paraquat

1992
Dose-dependent increases in metallothionein synthesis in the lung and liver of paraquat-treated rats.
    Toxicology and applied pharmacology, 1991, Volume: 107, Issue:1

    Topics: Animals; Body Weight; Dactinomycin; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver; Lung; Male; Metallothionein; Organ Size; Paraquat; Rats; Rats, Inbred Strains; Superoxides; Zinc

1991
Increase in metallothionein produced by chemicals that induce oxidative stress.
    Toxicology and applied pharmacology, 1991, Sep-01, Volume: 110, Issue:2

    Topics: Animals; Cisplatin; Cytosol; Diamide; Diquat; Doxorubicin; Ketones; Liver; Male; Maleates; Metallothionein; Metronidazole; Mice; Mice, Inbred Strains; Organ Specificity; Paraquat; Peroxides; Skatole; tert-Butylhydroperoxide; Vitamin K

1991
Enhanced lipid peroxidation is not necessary for induction of metallothionein-I by oxidative stress.
    Chemico-biological interactions, 1991, Volume: 78, Issue:2

    Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Fasting; Free Radicals; Kidney; Lipid Peroxides; Liver; Lung; Male; Metallothionein; Organ Size; Oxidation-Reduction; Paraquat; Rats; Rats, Inbred Strains; Stress, Physiological; Vitamin E; Zinc

1991
Metallothionein-I accumulation in the rat lung following a single paraquat administration.
    Toxicology letters, 1989, Volume: 45, Issue:1

    Topics: Animals; Kidney; Liver; Lung; Male; Metallothionein; Paraquat; Rats; Rats, Inbred Strains; Time Factors

1989
Antioxidative roles of metallothionein and manganese superoxide dismutase induced by tumor necrosis factor-alpha and interleukin-6.
    Archives of biochemistry and biophysics, 1995, Feb-01, Volume: 316, Issue:2

    Topics: Acute-Phase Proteins; Animals; Antioxidants; Carbon Tetrachloride; Cytokines; Dexamethasone; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Interleukin-6; Interleukins; Kidney; Liver; Liver Cirrhosis, Experimental; Male; Metallothionein; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha

1995
Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genes.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Animals; Cadmium; Catalase; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glutathione; Glutathione Peroxidase; Kinetics; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Oxidative Stress; Paraquat; Peroxides; Pregnancy; Superoxide Dismutase; tert-Butylhydroperoxide

1995
Response of Drosophila metallothionein promoters to metallic, heat shock and oxidative stresses.
    FEBS letters, 1996, Feb-12, Volume: 380, Issue:1-2

    Topics: Alcohol Dehydrogenase; Animals; beta-Galactosidase; Digestive System; Drosophila melanogaster; Gene Expression Regulation; Genes, Insect; Genes, Reporter; Heat-Shock Response; Homeostasis; Larva; Metallothionein; Metals; Oxidative Stress; Paraquat; Promoter Regions, Genetic; Transgenes

1996
Effect of glutathione depletion on metallothionein synthesis induced by paraquat in mice.
    The Tohoku journal of experimental medicine, 1995, Volume: 177, Issue:3

    Topics: Animals; Antimetabolites; Blotting, Northern; Buthionine Sulfoximine; Cadmium; Chlorides; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Dexamethasone; Glucocorticoids; Glutathione; Herbicides; Kidney; Liver; Male; Maleates; Metallothionein; Mice; Mice, Inbred ICR; Paraquat; Protein Synthesis Inhibitors; Zinc Compounds

1995
Involvement of oxidative stress in paraquat-induced metallothionein synthesis under glutathione depletion.
    Free radical biology & medicine, 1998, Volume: 24, Issue:9

    Topics: Animals; Buthionine Sulfoximine; Glutathione; Injections, Subcutaneous; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Oxidative Stress; Paraquat; Reactive Oxygen Species; Tumor Cells, Cultured

1998
Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines.
    Molecules and cells, 2000, Feb-29, Volume: 10, Issue:1

    Topics: Alkynes; Antineoplastic Agents; Camptothecin; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione Transferase; Glycine; Humans; Leukemia, Myeloid, Acute; Metallothionein; Paraquat; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Vincristine

2000
Altered Cu metabolism and differential transcription of Cu/ZnSod genes in a Cu/ZnSOD-deficient mutant of maize: evidence for a Cu-responsive transcription factor.
    Biochemistry, 2003, Feb-18, Volume: 42, Issue:6

    Topics: Copper; Electron Transport Complex IV; Enzyme Activation; Genes, Plant; Isoenzymes; Metallothionein; Models, Biological; Paraquat; Plant Proteins; Superoxide Dismutase; Transcription Factors; Transcription, Genetic; Zea mays; Zinc

2003
Cloning and functional study of a novel human metallothionein-I isoform induced by paraquat.
    Biochemical and biophysical research communications, 2003, May-02, Volume: 304, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Doxorubicin; Fluoresceins; Genetic Vectors; Humans; Metallothionein; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Paraquat; Protein Isoforms; Reactive Oxygen Species; Sequence Homology, Amino Acid; Tumor Cells, Cultured

2003
Property of metallothionein as a Zn pool differs depending on the induced condition of metallothionein.
    Toxicology letters, 2003, Apr-30, Volume: 142, Issue:1-2

    Topics: Animals; Binding, Competitive; Cadmium; Food Deprivation; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Paraquat; Protein Binding; Restraint, Physical; Stress, Physiological; Zinc

2003
Differential induction of Mn-containing superoxide dismutase by paraquat in peripheral lymphocytes of normal subjects and gastric cancer patients.
    Molecules and cells, 2003, Aug-31, Volume: 16, Issue:1

    Topics: Adult; Aged; Enzyme Induction; Female; Fluorescent Dyes; Humans; Lymphocytes; Male; Metallothionein; Middle Aged; Oxidative Stress; Paraquat; Reactive Oxygen Species; RNA, Messenger; Stomach Neoplasms; Superoxide Dismutase

2003
Overexpression of metallothionein protects cultured motor neurons against oxidative stress, but not mutant Cu/Zn-superoxide dismutase toxicity.
    Neurotoxicology, 2004, Volume: 25, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Chlorides; Genetic Vectors; Herbicides; Immunohistochemistry; Inclusion Bodies; Isoenzymes; Isomerism; Metallothionein; Mice; Motor Neurons; Mutation; Oxidative Stress; Paraquat; Plasmids; Superoxide Dismutase; Zinc Compounds

2004
Paraquat-induced gene expression in rat kidney.
    Archives of toxicology, 2006, Volume: 80, Issue:10

    Topics: Animals; Aspartate Aminotransferases; Gene Expression Profiling; Gene Expression Regulation; Glutathione Transferase; Heme Oxygenase (Decyclizing); Herbicides; Immunohistochemistry; Kidney; Metallothionein; Oligonucleotide Array Sequence Analysis; Paraquat; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Time Factors; Transcription, Genetic; Up-Regulation

2006
Expression of the PsMTA1 gene in white poplar engineered with the MAT system is associated with heavy metal tolerance and protection against 8-hydroxy-2'-deoxyguanosine mediated-DNA damage.
    Plant cell reports, 2009, Volume: 28, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Agrobacterium tumefaciens; Copper; Deoxyguanosine; DNA Damage; DNA, Plant; Gene Expression Regulation, Plant; Genes, Plant; Lipid Peroxidation; Metallothionein; Oxidative Stress; Paraquat; Pisum sativum; Plant Proteins; Plants, Genetically Modified; Populus; Reactive Oxygen Species; Transformation, Genetic; Zinc

2009
Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats.
    Free radical research, 2010, Volume: 44, Issue:8

    Topics: Animals; Blotting, Western; Cytochrome P-450 CYP2E1; Dopamine Plasma Membrane Transport Proteins; Glutathione Transferase; Male; Metallothionein; Motor Activity; Nerve Degeneration; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Tissue Distribution; Vesicular Monoamine Transport Proteins; Zinc

2010
C. elegans metallothioneins: response to and defence against ROS toxicity.
    Molecular bioSystems, 2011, Volume: 7, Issue:8

    Topics: Amino Acid Sequence; Analysis of Variance; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cluster Analysis; Eggs; Gene Deletion; Gene Knockout Techniques; Hydrogen Peroxide; Metabolomics; Metallothionein; Molecular Sequence Data; Oxidative Stress; Paraquat; Polymerase Chain Reaction; Reactive Oxygen Species

2011
Differential regulation of the rainbow trout (Oncorhynchus mykiss) MT-A gene by nuclear factor interleukin-6 and activator protein-1.
    BMC molecular biology, 2013, Dec-17, Volume: 14

    Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Metallothionein; Mutation; Oncorhynchus mykiss; Oxidative Stress; Paraquat; Phorbol Esters; Promoter Regions, Genetic; Transcription Factor AP-1; Transfection

2013
Metallothioneins attenuate paraquat-induced acute lung injury in mice through the mechanisms of anti-oxidation and anti-apoptosis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 73

    Topics: Acute Lung Injury; Animals; Antioxidants; Apoptosis; Catalase; Glutathione Peroxidase; Herbicides; Male; Metallothionein; Mice; Paraquat; Superoxide Dismutase

2014
Paraquat reduces natural killer cell activity via metallothionein induction.
    Journal of immunotoxicology, 2015, Volume: 12, Issue:4

    Topics: Animals; Cytotoxins; GATA3 Transcription Factor; Gene Expression Regulation; Immunosuppressive Agents; Killer Cells, Natural; Male; Metallothionein; Mice; Paraquat; Spleen; Zinc

2015
The effects of metallothionein in paraquat-induced Parkinson disease model of zebrafish.
    The International journal of neuroscience, 2023, Volume: 133, Issue:8

    Topics: Animals; Brain Injuries; Dopamine; Dopaminergic Neurons; Humans; Metallothionein; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neuroprotective Agents; Paraquat; Parkinson Disease; Substantia Nigra; Zebrafish

2023