Page last updated: 2024-08-21

paraquat and melatonin

paraquat has been researched along with melatonin in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (18.18)18.2507
2000's9 (27.27)29.6817
2010's16 (48.48)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Nagao, M; Takatori, T; Terazawa, K1
Attia, AM; Burgos, A; Hara, M; Melchiorri, D; Nistico, G; Reiter, RJ1
Chen, L; Hara, M; Melchiorri, D; Nisticò, G; Reiter, RJ; Sewerynek, E1
Daniels, WM; Melchiorri, D; Nisticò, G; Ortiz, GG; Pablos, MI; Reiter, RJ; Sewerynek, E1
Ayala, A; Bougria, M; Machado, A; Parrado, J1
Bitzer-Quintero, OK; García, JJ; Melchiorri, D; Oh, CS; Ortiz, GG; Pablos, MI; Reiter, RJ; Sewerynek, E; Zúñiga, G1
Antolín, I; Burkhardt, S; Coto-Montes, A; Fuhrberg, B; Hardeland, R1
Mohanan, PV; Yamamoto, HA1
Bonilla, E; Díaz, S; Medina-Leendertz, S1
Suntres, ZE1
Besson, MT; Birman, S; Iché, M; Rival, T; Soustelle, L; Strambi, C1
García-Rubio, L; Matas, P; Míguez, MP1
Bohórquez, A; Bonilla, E; Medina-Leendertz, S; Molero, L; Villalobos, V1
Ramírez-Zambrano, E; Rojas, G; Teneud, L; Zambrano, E; Zambrano, M1
Göcgeldi, E; Hasde, M; Korkmaz, A; Kurt, B; Ogur, R; Oter, S; Reiter, RJ; Topal, T; Uysal, B1
Jain, SK; Patel, DK; Singh, MP; Singhal, NK; Srivastava, G1
Choi, SI; Dadakhujaev, S; Im Kim, T; Kim, EK; Ryu, H1
Chauhan, AK; Jain, SK; Shanker, R; Singh, C; Singh, MP; Singhal, NK1
Arcaya, JL; Bonilla, E; Bravo, Y; Medina-Leendertz, S; Mora, M; Paz, M; Terán, R; Villalobos, V1
Baierle, M; Brucker, N; Bubols, GB; Charão, MF; Dias, BB; Fracasso, R; Garcia, SC; Gauer, B; Goethel, G; Guterres, SS; Matte, US; Moro, AM; Paese, K; Pohlmann, AR1
Ávila, DS; Barth, A; Brucker, N; Charão, MF; Eifler-Lima, VL; Fagundez, D; Garcia, SC; Guterres, SS; Jornada, DS; Pohlmann, AR; Souto, C1
Du, WH; Hao, HS; Pang, YW; Sun, WJ; Sun, YQ; Zhao, SJ; Zhu, HB1
Li, A; Li, H; Liu, S; Tian, Y; Wang, X; Zhao, Y1
Gao, HB; Gong, Y; Jin, YL; Meng, ZH; Shi, HW; Shi, Y; Tian, YP1
Gao, T; Li, C; Liang, B; Ma, F; Wei, Z; Zhao, Q1
Du, WH; Hao, HS; Jiang, XL; Pang, YW; Wang, L; Wang, YC; Wang, YY; Zhao, SJ; Zhao, XM; Zhu, HB1
Ding, F; Wang, G; Zhang, S1
Ivanets, EV; Menchinskaya, ES; Pislyagin, EA; Smetanina, OF; Trinh, PTH; Yurchenko, AN; Yurchenko, EA1
Brucker, N; Charão, MF; Eifler-Lima, VL; Garcia, SC; Goethel, G; Guterres, SS; Paese, K; Pohlmann, AR1
Jimenez-Del-Rio, M; Ortega-Arellano, HF; Velez-Pardo, C1
Shen, H; Yin, Y1

Reviews

1 review(s) available for paraquat and melatonin

ArticleYear
Role of antioxidants in paraquat toxicity.
    Toxicology, 2002, Oct-30, Volume: 180, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Glutathione; Herbicides; Humans; Iron Chelating Agents; Liposomes; Melatonin; Metallothionein; NADP; Oxidation-Reduction; Paraquat; Rats; Reactive Oxygen Species; Vitamin E

2002

Other Studies

32 other study(ies) available for paraquat and melatonin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Monoclonal antibodies against haptens.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1992, Volume: 46, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Diquat; Enzyme-Linked Immunosorbent Assay; Haptens; Melatonin; Methamphetamine; Mice; Mice, Inbred BALB C; Paraquat; Radioimmunoassay

1992
Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats.
    Life sciences, 1995, Volume: 56, Issue:2

    Topics: Aldehydes; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Lung; Lung Diseases; Male; Malondialdehyde; Melatonin; Oxidation-Reduction; Paraquat; Rats; Rats, Sprague-Dawley

1995
Paraquat toxicity and oxidative damage. Reduction by melatonin.
    Biochemical pharmacology, 1996, Apr-26, Volume: 51, Issue:8

    Topics: Animals; Antioxidants; Glutathione; Glutathione Disulfide; Herbicides; Lethal Dose 50; Lipid Peroxidation; Liver; Lung; Malondialdehyde; Melatonin; Oxidative Stress; Paraquat; Rats; Rats, Sprague-Dawley; Rats, Wistar

1996
Melatonin reduces paraquat-induced genotoxicity in mice.
    Toxicology letters, 1998, Mar-31, Volume: 95, Issue:2

    Topics: Animals; DNA Damage; Drug Interactions; Free Radicals; Herbicides; Male; Melatonin; Mice; Mice, Inbred ICR; Micronucleus Tests; Paraquat

1998
Induced mono-(ADP)-ribosylation of rat liver cytosolic proteins by lipid peroxidant agents.
    Free radical biology & medicine, 1999, Volume: 26, Issue:9-10

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Benzene Derivatives; Cyclic N-Oxides; Cytosol; Dithiothreitol; Female; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Liver; Malondialdehyde; Melatonin; Niacinamide; Nitrogen Oxides; Oxidants; Paraquat; Poly(ADP-ribose) Polymerases; Proteins; Rats; Rats, Wistar; tert-Butylhydroperoxide

1999
Genotoxicity of paraquat: micronuclei induced in bone marrow and peripheral blood are inhibited by melatonin.
    Mutation research, 2000, Jan-24, Volume: 464, Issue:2

    Topics: Animals; Bone Marrow; Chromosome Breakage; DNA; Erythroblasts; Herbicides; Injections, Intraperitoneal; Male; Melatonin; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagenicity Tests; Nucleic Acid Synthesis Inhibitors; Paraquat

2000
Melatonin and 5-methoxytryptamine in the bioluminescent dinoflagellate Gonyaulax polyedra. Restoration of the circadian glow peak after suppression of indoleamine biosynthesis or oxidative stress.
    Advances in experimental medicine and biology, 1999, Volume: 460

    Topics: 5-Methoxytryptamine; Animals; Buthionine Sulfoximine; Circadian Rhythm; Dinoflagellida; Hydrogen Peroxide; Indoles; Luminescent Measurements; Melatonin; Oxidative Stress; Paraquat; Photoperiod

1999
Effects of melatonin on paraquat or ultraviolet light exposure-induced DNA damage.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Animals; Brain; DNA; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Lung; Male; Melatonin; Mice; Mice, Inbred Strains; Paraquat; Radiation-Protective Agents; Ultraviolet Rays

2001
Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin.
    Experimental gerontology, 2002, Volume: 37, Issue:5

    Topics: Aging; Animals; Antioxidants; Drosophila melanogaster; Drug Resistance; Free Radical Scavengers; Free Radicals; Longevity; Male; Melatonin; Models, Biological; Oxidative Stress; Paraquat; Stress, Physiological; Temperature

2002
Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain.
    Current biology : CB, 2004, Apr-06, Volume: 14, Issue:7

    Topics: Animals; Brain; DNA Primers; Drosophila; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Fluorescence; Gene Silencing; Glutamic Acid; Humans; Melatonin; Microscopy, Electron, Scanning; Movement; Nerve Degeneration; Neuropil; Oxidative Stress; Paraquat; Reverse Transcriptase Polymerase Chain Reaction; Riluzole; RNA Interference

2004
Protective effect of melatonin on paraquat-induced cytotoxicity in isolated rat hepatocytes.
    Human & experimental toxicology, 2005, Volume: 24, Issue:9

    Topics: Animals; Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Hepatocytes; Herbicides; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Time Factors

2005
Paraquat-induced oxidative stress in drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid.
    Neurochemical research, 2006, Volume: 31, Issue:12

    Topics: Animals; Antioxidants; Ascorbic Acid; Drosophila melanogaster; Drug Resistance; Glutathione; Herbicides; Male; Melatonin; Minocycline; Oxidative Stress; Paraquat; Serotonin; Survival Rate; Thioctic Acid

2006
[Protective effect of melatonin and sodium thiosulphate on histopathology and ultrastructure of the kidney in rats with acute paraquat poisoning].
    Investigacion clinica, 2007, Volume: 48, Issue:1

    Topics: Acute Disease; Animals; Antidotes; Antioxidants; Drug Evaluation, Preclinical; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Melatonin; Paraquat; Rats; Rats, Wistar; Thiosulfates

2007
Establishing the use of melatonin as an adjuvant therapeutic against paraquat-induced lung toxicity in rats.
    Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:9

    Topics: Adjuvants, Pharmaceutic; Animals; Antioxidants; Biomarkers; Lung Diseases; Male; Melatonin; Nitrogen Compounds; Oxidative Stress; Paraquat; Rats; Rats, Wistar

2008
Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse.
    Journal of pineal research, 2011, Volume: 50, Issue:2

    Topics: Animals; Blotting, Western; Cytochrome P-450 CYP2E1; Dopamine; Lipid Peroxidation; Male; Maneb; Melatonin; Mice; Paraquat; Parkinson Disease; Polymerase Chain Reaction; Silymarin; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2011
Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors.
    Journal of pineal research, 2011, Volume: 51, Issue:1

    Topics: Analysis of Variance; Antioxidants; Blotting, Western; Catalase; Cell Survival; Cells, Cultured; Cornea; Corneal Dystrophies, Hereditary; Fibroblasts; Flow Cytometry; Glutathione Reductase; Humans; Hydrogen Peroxide; Immunohistochemistry; Melatonin; Oxidative Stress; Paraquat; Reactive Oxygen Species; Receptors, Melatonin; Superoxide Dismutase

2011
Silymarin- and melatonin-mediated changes in the expression of selected genes in pesticides-induced Parkinsonism.
    Molecular and cellular biochemistry, 2013, Volume: 384, Issue:1-2

    Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Disease Models, Animal; Gene Expression Regulation; Inflammation; Ion Channels; Male; Maneb; Melatonin; Mice; Mitochondria; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides; Signal Transduction; Silymarin

2013
Longterm melatonin administration alleviates paraquat mediated oxidative stress in Drosophila melanogaster.
    Investigacion clinica, 2014, Volume: 55, Issue:4

    Topics: Animals; Antioxidants; Catalase; Drosophila melanogaster; Drosophila Proteins; Drug Evaluation, Preclinical; Herbicides; Hydrogen Peroxide; Lipid Peroxidation; Longevity; Male; Malondialdehyde; Melatonin; Mitochondria; Motor Activity; Oxidative Stress; Paraquat

2014
Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Volume: 784-785

    Topics: Antioxidants; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Culture Media; DNA Damage; Humans; Melatonin; Nanocapsules; Paraquat; Particle Size; Pulmonary Alveoli

2015
Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Caenorhabditis elegans; Melatonin; Nanocapsules; Paraquat

2015
Melatonin inhibits paraquat-induced cell death in bovine preimplantation embryos.
    Journal of pineal research, 2016, Volume: 60, Issue:2

    Topics: Animals; Apoptosis; Blastocyst; Caspase 3; Cattle; Female; MAP Kinase Signaling System; Melatonin; Paraquat; Pesticides; Proto-Oncogene Proteins c-bcl-2; X-Linked Inhibitor of Apoptosis Protein

2016
[The expressions of P38 mitogen-activated protein kinases and JNK mitogen-activated protein kinases in the renal tissue of rats with acute paraquat poisoning and the therapeutical effects of melatonin].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2015, Volume: 33, Issue:5

    Topics: Animals; Female; JNK Mitogen-Activated Protein Kinases; Kidney; Male; Melatonin; p38 Mitogen-Activated Protein Kinases; Paraquat; Rats; Rats, Sprague-Dawley

2015
[The expressions of intercellular adhesion molecule-1 in renal tissue of rats with paraquat poisoning and the effect of melatonin].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2016, Mar-20, Volume: 34, Issue:3

    Topics: Animals; Immunohistochemistry; Intercellular Adhesion Molecule-1; Kidney; Melatonin; Mitochondria; Paraquat; Rats; Rats, Sprague-Dawley

2016
Effects of Exogenous Melatonin on Methyl Viologen-Mediated Oxidative Stress in Apple Leaf.
    International journal of molecular sciences, 2018, Jan-21, Volume: 19, Issue:1

    Topics: Antioxidants; Chlorophyll; Lipid Peroxidation; Malus; Melatonin; Oxidative Stress; Paraquat; Phenotype; Plant Leaves; Reactive Oxygen Species; Stress, Physiological

2018
Melatonin protects against paraquat-induced damage during in vitro maturation of bovine oocytes.
    Journal of pineal research, 2019, Volume: 66, Issue:1

    Topics: Animals; Antioxidants; Cattle; Female; Glutathione; Melatonin; Oocytes; Paraquat; Reactive Oxygen Species

2019
Exogenous Melatonin Mitigates Methyl Viologen-Triggered Oxidative Stress in Poplar Leaf.
    Molecules (Basel, Switzerland), 2018, Nov-02, Volume: 23, Issue:11

    Topics: Antioxidants; Cell Membrane; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Melatonin; Oxidation-Reduction; Oxidative Stress; Paraquat; Plant Leaves; Populus; Proline; Reactive Oxygen Species

2018
Neuroprotective Activity of Some Marine Fungal Metabolites in the 6-Hydroxydopamin- and Paraquat-Induced Parkinson's Disease Models.
    Marine drugs, 2018, Nov-21, Volume: 16, Issue:11

    Topics: Alkaloids; Animals; Antioxidants; Antiparkinson Agents; Aquatic Organisms; Aspergillus; Biological Products; Cell Line, Tumor; Cell Survival; Melatonin; Mice; Neuroprotective Agents; Oxidopamine; Paraquat; Parkinsonian Disorders; Penicillium; Polyketides; Reactive Oxygen Species

2018
Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans.
    BMC pharmacology & toxicology, 2019, 12-19, Volume: 20, Issue:Suppl 1

    Topics: Animals; Antioxidants; Caenorhabditis elegans; Drug Carriers; Drug Compounding; Lipid Peroxidation; Lipids; Melatonin; Nanocapsules; Paraquat; Particle Size; Superoxide Dismutase

2019
Melatonin Increases Life Span, Restores the Locomotor Activity, and Reduces Lipid Peroxidation (LPO) in Transgenic Knockdown Parkin Drosophila melanogaster Exposed to Paraquat or Paraquat/Iron.
    Neurotoxicity research, 2021, Volume: 39, Issue:5

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Drosophila melanogaster; Drosophila Proteins; Female; Gene Knockdown Techniques; Iron; Lipid Peroxidation; Locomotion; Longevity; Melatonin; Paraquat; Ubiquitin-Protein Ligases

2021
Melatonin ameliorates acute lung injury caused by paraquat poisoning by promoting PINK1 and BNIP3 expression.
    Toxicology, 2023, 05-15, Volume: 490

    Topics: Acute Lung Injury; Animals; DNA, Mitochondrial; Lung; Melatonin; Paraquat; Protein Kinases

2023