paraquat has been researched along with maneb in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.30) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 22 (28.57) | 29.6817 |
| 2010's | 43 (55.84) | 24.3611 |
| 2020's | 11 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chandrashekar, KR; Kaveriappa, KM | 1 |
| Baggs, RB; Brockel, BJ; Cory-Slechta, DA; Richfield, EK; Thiruchelvam, M | 1 |
| Baggs, RB; Cory-Slechta, DA; Richfield, EK; Tank, AW; Thiruchelvam, M | 1 |
| Baggs, RB; Cory-Slechta, DA; Goodman, BM; Richfield, EK; Thiruchelvam, M | 1 |
| Baggs, RB; Cory-Slechta, DA; Di Monte, DA; McCormack, A; Richfield, EK; Tank, AW; Thiruchelvam, M | 1 |
| Uversky, VN | 1 |
| Buckley, B; Cory-Slechta, DA; Mirochnitchenko, O; Prokopenko, O; Richfield, EK; Thiruchelvam, M | 1 |
| Barlow, BK; Cory-Slechta, DA; Richfield, EK; Thiruchelvam, M | 1 |
| Benítez-Díaz, P; Dávila-Ovalles, R; Miranda-Contreras, L; Palacios-Prü, E; Peña-Contreras, Z | 1 |
| Kadota, S; Li, X; Matsumoto, K; Murakami, Y; Tezuka, Y; Wu, Y | 1 |
| Finley, B; Li, AA; McIntosh, LJ; Mink, PJ; Teta, MJ | 1 |
| Cicchetti, F; Ficke, BW; Gross, RE; Jimenez, L; Lapointe, N; Roberge-Tremblay, A; Saint-Pierre, M | 1 |
| Gupta, YK; Kumar, A; Patel, S; Singh, MP; Singh, V | 1 |
| Kordower, JH; O'Malley, J; Soderstrom, K; Steece-Collier, K | 1 |
| Cicchetti, F; Gross, RE; Saint-Pierre, M; Sik, A; Tremblay, ME | 1 |
| Giasson, BI; Lee, VM; Leight, S; Norris, EH; Trojanowski, JQ; Uryu, K | 1 |
| Ethell, DW; Fei, Q | 1 |
| Patel, S; Singh, K; Singh, MP; Singh, S | 1 |
| Dhanasekaran, M; Karuppagounder, SS; Suppiramaniam, V; Thrash, B; Uthayathas, S | 1 |
| Ahmad, I; Kumar, A; Prasad Pandey, H; Shukla, S; Singh, C | 1 |
| Bronstein, J; Cockburn, M; Costello, S; Ritz, B; Zhang, X | 1 |
| Bronstein, J; Cockburn, M; Costello, S; Farrer, MJ; Lincoln, SJ; Manthripragada, AD; Ritz, BR | 1 |
| Cicchetti, F; Drouin-Ouellet, J; Gross, RE | 1 |
| Irizarry, MC; Kachroo, A; Schwarzschild, MA | 1 |
| Gupta, SP; Patel, S; Singh, AK; Singh, MP; Singh, S; Yadav, S | 1 |
| Bernard, LP; Guilford, FT; Zeevalk, GD | 1 |
| Bronstein, J; Cockburn, M; Farrer, M; Gatto, NM; Manthripragada, AD; Rhodes, SL; Ritz, B | 1 |
| Ahmad, I; Kumar, A; Pandey, HP; Patel, DK; Shukla, S; Singh, BK; Singh, C | 1 |
| Jain, SK; Patel, DK; Singh, MP; Singhal, NK; Srivastava, G | 1 |
| Colosio, C; Moretto, A | 1 |
| Go, YM; Hansen, JM; Jones, DP; Roede, JR | 1 |
| Bronstein, J; Cockburn, M; Costello, S; Ritz, B; Wang, A; Zhang, X | 1 |
| Cai, XY; Chen, RR; He, DF; Xu, HY | 1 |
| Cai, X; Chen, R; He, D; Xu, H | 1 |
| Gupta, SP; Singh, MP; Srivastava, G; Srivastava, PK; Yadav, S | 1 |
| Credle, J; Duka, V; Jones, J; Lee, JH; Oaks, AW; Sidhu, A; Wills, J | 1 |
| Dixit, A; Patel, DK; Prakash, O; Singh, MP; Srivastava, G; Yadav, S | 1 |
| Beal, MF; Calingasan, NY; Elemento, O; Gollamudi, S; Johri, A; Yang, L | 1 |
| Desplats, P; Fujita, M; Hashimoto, M; Kosberg, K; Mante, M; Masliah, E; Patel, P; Patrick, C; Rockenstein, E | 1 |
| Ahmad, I; Chauhan, AK; Kumar, A; Kumar, V; Pandey, HP; Shukla, S; Singh, BK; Singh, C; Singh, D | 1 |
| Chouhan, S; Prakash, J; Singh, SP; Yadav, SK | 1 |
| Andrieu, T; Baron, T; Bétemps, D; Chorfa, A; Hogeveen, K; Lazizzera, C; Morignat, E | 1 |
| Dixit, A; Mishra, M; Prakash, O; Singh, MP; Singh, PK; Srivastava, G; Verma, D | 1 |
| Chauhan, AK; Jain, SK; Shanker, R; Singh, C; Singh, MP; Singhal, NK | 1 |
| Allen, JL; Conrad, K; Cory-Slechta, DA; Liu, X; Oberdörster, G; Weston, D | 1 |
| Baltazar, MT; Carvalho, F; de Lourdes Bastos, M; Dinis-Oliveira, RJ; Duarte, JA; Tsatsakis, AM | 1 |
| Kachroo, A; Schwarzschild, MA | 1 |
| Ahmad, I; Chauhan, AK; Kumar, V; Pandey, HP; Patel, DK; Shukla, S; Singh, BK; Singh, C; Singh, D | 1 |
| Jones, DP; Roede, JR | 1 |
| Assani, K; Barajas, A; Krantz, DE; Lawal, HO; Lawless, G; Lumintang, YP; Martin, CA; Nunez, V | 1 |
| Corbett, J; Kadiiska, MB; Kumar, A; Leinisch, F; Mason, RP | 1 |
| Ahmad, I; Chauhan, AK; Kumar, V; Pandey, HP; Shukla, S; Singh, C; Singh, D; Singh, S | 1 |
| Benazzouz, A; Bouabid, S; De Deurwaerdère, P; Faggiani, E; Lakhdar-Ghazal, N; Tinakoua, A | 1 |
| Candeletti, S; Caputi, FF; Carretta, D; Lattanzio, F; Palmisano, M; Romualdi, P | 1 |
| Jha, RR; Kumari, R; Patel, DK; Singh, MP | 1 |
| He, X; Li, B; Sun, Y | 1 |
| Ganini, D; Kumar, A; Mason, RP | 1 |
| Kumar, V; Singh, C; Singh, D | 1 |
| Ackerson, LC; Cely, I; Chesselet, MF; De La Rosa, K; Gabby, L; Maidment, NT; McDowell, KA; Mortazavi, F; Mulligan, CK; Murphy, NP; Richter, F; Sioshansi, PC; Tsan, L | 1 |
| Che, Y; Hou, L; Liu, X; Sun, F; Wang, H; Wang, K; Wang, Q; Zhang, C; Zhao, X; Zhou, X | 1 |
| Huang, C; Li, BX; Ma, J; Ma, K; Sun, Y; Wu, YP | 1 |
| Che, Y; Hou, L; Sun, F; Wang, Q | 1 |
| Che, Y; Hou, L; Li, H; Liu, X; Piao, F; Sun, F; Wang, Q; Zhang, C; Zhang, D | 1 |
| Bordelon, Y; Bronstein, JM; Cockburn, M; Paul, KC; Ritz, B; Sinsheimer, JS | 1 |
| Ceccatelli, S; Colle, D; Farina, M; Raciti, M | 1 |
| Hou, L; Huang, R; Sun, F; Wang, Q; Zhang, L | 1 |
| Colle, D; Farina, M; Ghizoni, H; Gonçalves, CL; Hort, MA; Naime, AA; Santos, DB | 1 |
| Ding, W; Hong, X; Ji, D; Lin, H; Wu, F | 1 |
| Hou, L; Huang, R; Qiu, X; Qu, X; Wang, Q; Zhao, X | 1 |
| Guan, X; Li, B; Li, C; Liu, F; Yuan, M | 1 |
| Hou, L; Qiu, X; Wang, Q; Zhang, C; Zhao, X | 1 |
| Singh, C; Singh, D; Yadav, A | 1 |
| Jimenez-Del-Rio, M; Ortega-Arellano, HF; Quintero-Espinosa, DA; Velez-Pardo, C | 1 |
| Chandrasekhar, M; Dey, A; Gopalakrishnan, AV; Iyer, M; Kesari, K; Narayanasamy, A; Sri Sabari, S; Vellingiri, B; Venkatesan, D | 1 |
| Dai, L; Du, Z; Fang, Y; Jiang, H; Li, F; Li, H; Liu, C; Liu, Z; Meng, L; Tian, Y; Wang, Z; Xiong, M; Yan, Z; Yu, T; Yuan, X; Zhang, J; Zhang, Z | 1 |
| Singh, C; Yadav, A | 1 |
| Chang, R; Hou, L; Huang, R; Liu, J; Ruan, Z; Sun, F; Wang, Q; Wang, Y; Zhao, J | 1 |
8 review(s) available for paraquat and maneb
| Article | Year |
|---|---|
Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration.
Topics: Animals; Disease Models, Animal; Fungicides, Industrial; Herbicides; Maneb; Nerve Degeneration; Neurotoxins; Paraquat; Parkinson Disease; Rotenone; Uncoupling Agents | 2004 |
Evaluation of epidemiologic and animal data associating pesticides with Parkinson's disease.
Topics: Animals; Case-Control Studies; Dieldrin; Disease Models, Animal; Fungicides, Industrial; Heptachlor; Humans; Maneb; Occupational Diseases; Occupational Exposure; Paraquat; Parkinson Disease; Permethrin; Pesticides; Pyridazines; Risk Factors | 2005 |
Neural repair strategies for Parkinson's disease: insights from primate models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Transplantation; Deep Brain Stimulation; Disease Models, Animal; Fungicides, Industrial; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Maneb; Nerve Degeneration; Oxidopamine; Paraquat; Parkinson Disease; Pesticides; Primates; Rotenone | 2006 |
Paraquat and maneb induced neurotoxicity.
Topics: Animals; Apoptosis; Drug Interactions; Fungicides, Industrial; Herbicides; Humans; Inflammation; Maneb; Mitochondria; Necrosis; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Parkinson Disease, Secondary | 2007 |
Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
Topics: Animals; Disease Models, Animal; Environmental Exposure; Humans; Maneb; Paraquat; Parkinson Disease, Secondary; Pesticides; Rotenone | 2009 |
Biochemical and toxicological evidence of neurological effects of pesticides: the example of Parkinson's disease.
Topics: Animals; Brain; Dieldrin; Dose-Response Relationship, Drug; Humans; Maneb; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Pyrethrins; Risk Assessment; Risk Factors; Rotenone; Time Factors; Toxicity Tests | 2011 |
Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases--a mechanistic approach.
Topics: Animals; Apoptosis; Dieldrin; Environmental Exposure; Humans; Maneb; Neurodegenerative Diseases; Organophosphates; Oxidative Stress; Paraquat; Parkinson Disease, Secondary; Pesticides; Proteasome Inhibitors; Pyrethrins | 2014 |
Neurotoxicity of pesticides - A link to neurodegeneration.
Topics: Dopamine; Humans; Maneb; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides | 2022 |
69 other study(ies) available for paraquat and maneb
| Article | Year |
|---|---|
Effect of pesticides on the growth of aquatic hyphomycetes.
Topics: Captan; Cyclohexenes; Maneb; Mitosporic Fungi; Paraquat; Pesticides; Water Microbiology; Zineb | 1989 |
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease?
Topics: Animals; Body Weight; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Environmental Exposure; Lung; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Neural Pathways; Neurons; Paraquat; Parkinsonian Disorders; Risk Factors; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2000 |
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Carrier Proteins; Cell Count; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Drug Synergism; Glial Fibrillary Acidic Protein; Gliosis; Injections, Intraperitoneal; Lung; Male; Maneb; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Paraquat; Parkinson Disease, Secondary; Substantia Nigra; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2000 |
Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Cell Count; Chromatography, High Pressure Liquid; Dopamine; Fungicides, Industrial; Herbicides; Homovanillic Acid; Immunohistochemistry; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease; Phenotype; Serotonin; Tyrosine 3-Monooxygenase | 2002 |
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype.
Topics: Aging; Animals; Cell Count; Corpus Striatum; Disease Susceptibility; Dopamine; Drug Combinations; Glutamate Decarboxylase; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Neurotoxins; Paraquat; Parkinson Disease, Secondary; Phenotype; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 2003 |
[WITHDRAWN] Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Body Weight; Cerebral Cortex; Corpus Striatum; Dopamine; Fungicides, Industrial; Glutathione Peroxidase; Herbicides; Hydrogen Peroxide; Immunohistochemistry; Lipid Metabolism; Lipid Peroxidation; Maneb; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Oxidative Stress; Paraquat; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Serotonin; Signal Transduction; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase | 2005 |
Developmental pesticide models of the Parkinson disease phenotype.
Topics: Age Factors; Animals; Animals, Newborn; Dopamine; Drug Synergism; Female; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Mice, Inbred C57BL; Models, Biological; Motor Activity; Paraquat; Parkinson Disease; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Substantia Nigra | 2005 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicides, Industrial; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Herbicides; Hyperkinesis; Maneb; Mice; Motor Activity; Neural Inhibition; Paraquat; Pregnancy; Prenatal Exposure Delayed Effects; Synaptic Transmission; Zineb | 2005 |
Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Dopamine; Fungicides, Industrial; Herbicides; Immunohistochemistry; Levodopa; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nerve Degeneration; Neuroprotective Agents; Paraquat; Parkinson Disease, Secondary; Phytotherapy; Plant Roots; Polygonum; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Systemic exposure to paraquat and maneb models early Parkinson's disease in young adult rats.
Topics: Age of Onset; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Encephalitis; Fungicides, Industrial; Gliosis; Herbicides; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substantia Nigra | 2005 |
Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration.
Topics: Analysis of Variance; Animals; Catalase; Corpus Striatum; Cytochrome P-450 CYP2E1; Disease Models, Animal; Gene Expression; Glutathione Transferase; Herbicides; Lipid Peroxidation; Male; Maneb; Mice; Paraquat; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Time Factors | 2006 |
Temporal effects of paraquat/maneb on microglial activation and dopamine neuronal loss in older rats.
Topics: Aging; Animals; Cell Death; Dopamine; Drug Administration Schedule; Drug Combinations; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model.
Topics: alpha-Synuclein; Animals; Brain; Drug Synergism; Environmental Exposure; Fungicides, Industrial; Humans; Inclusion Bodies; Maneb; Mice; Mice, Transgenic; Mitochondria; Mutation, Missense; Paraquat; Parkinson Disease | 2007 |
Maneb potentiates paraquat neurotoxicity by inducing key Bcl-2 family members.
Topics: bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; Drug Synergism; Herbicides; Humans; Maneb; Multigene Family; Paraquat; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2008 |
Gene expression profiles of mouse striatum in control and maneb + paraquat-induced Parkinson's disease phenotype: validation of differentially expressed energy metabolizing transcripts.
Topics: Animals; Blotting, Western; Corpus Striatum; Disease Models, Animal; Energy Metabolism; Fungicides, Industrial; Gene Expression Profiling; Herbicides; Male; Maneb; Mice; Oligonucleotide Array Sequence Analysis; Paraquat; Phenotype; RNA, Messenger | 2008 |
The involvement of nitric oxide in maneb- and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes.
Topics: Animals; Catalase; Enzyme Inhibitors; Glutathione Transferase; Guanidines; Lipid Peroxidation; Male; Maneb; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Peroxidase; Pesticides; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors | 2008 |
Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California.
Topics: Adult; Aged; Aged, 80 and over; Agriculture; California; Case-Control Studies; Comorbidity; Environmental Exposure; Environmental Monitoring; Epidemiological Monitoring; Female; Humans; Male; Maneb; Middle Aged; Odds Ratio; Paraquat; Parkinson Disease; Pesticides; Population Surveillance; Smoking | 2009 |
Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Topics: Case-Control Studies; Dopamine Plasma Membrane Transport Proteins; Environmental Exposure; Environmental Pollutants; Female; Genetic Variation; Genotype; Humans; Male; Maneb; Middle Aged; Paraquat; Parkinson Disease; Pesticides; Polymorphism, Single Nucleotide; Risk Factors | 2009 |
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.
Topics: Animals; Caffeine; Cell Count; Chronic Disease; Disease Models, Animal; Dopamine; Drug Interactions; Fungicides, Industrial; Herbicides; Locomotion; Male; Maneb; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Paraquat; Substantia Nigra | 2010 |
Involvement of nitric oxide in maneb- and paraquat-induced Parkinson's disease phenotype in mouse: is there any link with lipid peroxidation?
Topics: Animals; Corpus Striatum; Guanidines; Lipid Peroxidation; Male; Maneb; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Paraquat; Parkinson Disease, Secondary; Pesticides; Phenotype; RNA, Messenger; Second Messenger Systems; Tyrosine 3-Monooxygenase | 2010 |
Liposomal-glutathione provides maintenance of intracellular glutathione and neuroprotection in mesencephalic neuronal cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Glutathione; Glycerol; Intracellular Space; Lecithins; Liposomes; Maneb; Mesencephalon; Neurons; Neuroprotective Agents; Paraquat; Parkinson Disease; Pesticides; Rats; Rats, Sprague-Dawley | 2010 |
α-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease.
Topics: Age of Onset; Aged; alpha-Synuclein; California; Causality; Comorbidity; Educational Status; Environmental Exposure; Female; Fungicides, Industrial; Herbicides; Humans; Male; Maneb; Paraquat; Parkinson Disease; Risk Assessment; Rural Health; Smoking | 2010 |
Maneb and paraquat-induced modulation of toxicant responsive genes in the rat liver: comparison with polymorphonuclear leukocytes.
Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Maneb; Neutrophils; Oxidative Stress; Paraquat; Pesticides; Rats; Rats, Wistar | 2010 |
Melatonin or silymarin reduces maneb- and paraquat-induced Parkinson's disease phenotype in the mouse.
Topics: Animals; Blotting, Western; Cytochrome P-450 CYP2E1; Dopamine; Lipid Peroxidation; Male; Maneb; Melatonin; Mice; Paraquat; Parkinson Disease; Polymerase Chain Reaction; Silymarin; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2011 |
Maneb and paraquat-mediated neurotoxicity: involvement of peroxiredoxin/thioredoxin system.
Topics: Cell Line; Dopamine; Glutathione; Humans; Maneb; Neurons; Neurotoxicity Syndromes; Neurotoxins; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Paraquat; Parkinson Disease; Peroxiredoxins; Pesticides; Reactive Oxygen Species; Thioredoxins; Transcription Factors | 2011 |
Parkinson's disease risk from ambient exposure to pesticides.
Topics: Age Factors; California; Environmental Exposure; Female; Geographic Information Systems; Humans; Male; Maneb; Middle Aged; Occupational Exposure; Paraquat; Parkinson Disease, Secondary; Pesticides; Risk Factors; Smoking; Socioeconomic Factors; Ziram | 2011 |
[Effects of co-exposure to paraquat and maneb on system of substantial nigra and striatum in rats].
Topics: Animals; Corpus Striatum; Male; Maneb; Paraquat; Parkinsonian Disorders; Pesticides; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2011 |
Differential effects of activating D1 and D2 receptors on electrophysiology of neostriatal neurons in a rat model of Parkinson's disease induced by paraquat and maneb.
Topics: Animals; Disease Models, Animal; Electrophysiological Phenomena; Fungicides, Industrial; Herbicides; Male; Maneb; Neocortex; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2011 |
Role of secondary mediators in caffeine-mediated neuroprotection in maneb- and paraquat-induced Parkinson's disease phenotype in the mouse.
Topics: Animals; Caffeine; Inflammation Mediators; Male; Maneb; Mice; Neuroprotective Agents; Nitric Oxide; Paraquat; Parkinson Disease, Secondary; Phenotype | 2012 |
Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways.
Topics: alpha-Synuclein; Animals; Autophagy; Case-Control Studies; Corpus Striatum; Down-Regulation; Fungicides, Industrial; Herbicides; Humans; Male; Maneb; Mice; Mice, Inbred C57BL; Paraquat; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Signal Transduction; Tauopathies | 2012 |
Resveratrol potentiates cytochrome P450 2 d22-mediated neuroprotection in maneb- and paraquat-induced parkinsonism in the mouse.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dopamine; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2012 |
Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.
Topics: Animals; Corpus Striatum; Gene Expression Profiling; Gene Regulatory Networks; Humans; Male; Maneb; Mesencephalon; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Pesticides; Pyridazines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcriptome | 2012 |
Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Gene Expression Regulation; Gene-Environment Interaction; Hippocampus; Humans; Immunohistochemistry; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Maneb; Mice; Mice, Transgenic; Neurogenesis; Paraquat; Parkinson Disease; Pesticides; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Transcription, Genetic | 2012 |
Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochromes; Drug Interactions; Glutathione; Herbicides; Histocytochemistry; Interleukin-1beta; Liver; Male; Maneb; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Silymarin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Neuroprotective role of Withania somnifera root extract in maneb-paraquat induced mouse model of parkinsonism.
Topics: Animals; Disease Models, Animal; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Plant Extracts; Plant Roots; Withania | 2013 |
Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines.
Topics: alpha-Synuclein; Cell Death; Cell Line, Tumor; Cell Survival; Glycine; Glyphosate; Humans; Insecticides; Maneb; Melanoma; Neuroblastoma; Paraquat; Parkinson Disease; Rotenone; Transduction, Genetic | 2013 |
Minocycline, levodopa and MnTMPyP induced changes in the mitochondrial proteome profile of MPTP and maneb and paraquat mice models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine; Homeodomain Proteins; Levodopa; Male; Maneb; Metalloporphyrins; Mice; Microglia; Minocycline; Mitochondria; Paraquat; Parkinson Disease, Secondary; Proteome; Stathmin; Superoxide Dismutase | 2013 |
Silymarin- and melatonin-mediated changes in the expression of selected genes in pesticides-induced Parkinsonism.
Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Disease Models, Animal; Gene Expression Regulation; Inflammation; Ion Channels; Male; Maneb; Melatonin; Mice; Mitochondria; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides; Signal Transduction; Silymarin | 2013 |
Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice.
Topics: Air Pollutants; Animals; Animals, Newborn; Cell Count; Corpus Striatum; Disease Models, Animal; Drug Combinations; Female; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Nanoparticles; Paraquat; Parkinson Disease; Particulate Matter; Silicones; Substantia Nigra; Tyrosine 3-Monooxygenase | 2014 |
Allopurinol reduces levels of urate and dopamine but not dopaminergic neurons in a dual pesticide model of Parkinson's disease.
Topics: Allopurinol; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Enzyme Inhibitors; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease; Pesticides; Uric Acid | 2014 |
CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb- and paraquat-treated rat polymorphonuclear leukocytes.
Topics: Animals; Cytochrome P-450 CYP2E1; Glutathione Transferase; Heme Oxygenase-1; Lipid Peroxidation; Maneb; Neutrophils; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Rats; Reactive Oxygen Species | 2014 |
Thiol-reactivity of the fungicide maneb.
Topics: Fungicides, Industrial; Humans; Maneb; Paraquat; Protein Binding; Recombinant Proteins; Sulfhydryl Compounds; Thioredoxins | 2014 |
Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.
Topics: Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Maneb; Motor Activity; Paraquat; Parkinson Disease, Secondary; Pesticides; Survival Analysis; Ubiquitin-Protein Ligases; Ziram | 2014 |
Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Cyclic N-Oxides; Disease Models, Animal; Dopaminergic Neurons; Injections, Intraperitoneal; Male; Maneb; Mesencephalon; Mice, Inbred C57BL; Microglia; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase Type II; Paraquat; Parkinson Disease; Peroxynitrous Acid; Spin Labels; Substantia Nigra; Tyrosine 3-Monooxygenase | 2016 |
NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.
Topics: Acetophenones; Animals; Enzyme Inhibitors; Fungicides, Industrial; Herbicides; Maneb; Mitochondria; NADPH Oxidases; Neutrophils; Oxidative Stress; Paraquat; Rats; Reactive Oxygen Species | 2015 |
The impact of combined administration of paraquat and maneb on motor and non-motor functions in the rat.
Topics: Animals; Anxiety Disorders; Central Nervous System Agents; Corpus Striatum; Depressive Disorder; Dopamine; Male; Maneb; Motor Activity; Neurons; Norepinephrine; Paraquat; Parkinsonian Disorders; Rats, Sprague-Dawley; Serotonin; Subthalamic Nucleus | 2015 |
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells.
Topics: alpha-Synuclein; ATPases Associated with Diverse Cellular Activities; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Insecticides; Maneb; Models, Biological; Neuroblastoma; Paraquat; Parkinson Disease, Secondary; Proteasome Endopeptidase Complex; Receptors, Opioid; Tyrosine 3-Monooxygenase | 2015 |
Whirling agitated single drop microextraction technique for the simultaneous analysis of Paraquat and Maneb in tissue samples of treated mice.
Topics: Animals; Chromatography, High Pressure Liquid; Injections, Intraperitoneal; Liquid Phase Microextraction; Male; Maneb; Mice; Paraquat; Particle Size; Tandem Mass Spectrometry | 2016 |
Developmental exposure to paraquat and maneb can impair cognition, learning and memory in Sprague-Dawley rats.
Topics: Animals; Behavior, Animal; Biomarkers; Body Weight; Cognition; Female; Fungicides, Industrial; Herbicides; Hippocampus; Immunohistochemistry; Learning; Male; Maneb; Maternal Exposure; Memory; Paraquat; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2016 |
Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Cell Death; Cytochromes c; Free Radicals; Immunohistochemistry; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neurons; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides | 2016 |
IFN-γ regulates xanthine oxidase-mediated iNOS-independent oxidative stress in maneb- and paraquat-treated rat polymorphonuclear leukocytes.
Topics: Animals; Interferon-gamma; Male; Maneb; Neutrophils; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Xanthine Oxidase | 2017 |
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Topics: Aging; Animals; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Genetic Variation; Male; Maneb; Mice, Knockout; Mice, Mutant Strains; Paraquat; Parkinson Disease; Pars Compacta; Risk | 2017 |
Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation.
Topics: Acetophenones; Adrenergic Neurons; Animals; Disease Models, Animal; Enzyme Inhibitors; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Microglia; NADPH Oxidases; Nerve Degeneration; Neurotoxicity Syndromes; NF-kappa B; Paraquat; Parkinson Disease; Risk Factors | 2017 |
Effect of Wnt1 and Wnt5a on the development of dopaminergic neurons, and toxicity induced by combined exposure to paraquat and maneb during gestation and lactation.
Topics: Animals; Corpus Striatum; Dopamine; Dopaminergic Neurons; Female; Gene Expression Regulation; Lactation; Maneb; Nuclear Receptor Subfamily 4, Group A, Member 2; Paraquat; Pregnancy; Rats; Substantia Nigra; Tyrosine 3-Monooxygenase; Wnt-5a Protein; Wnt1 Protein | 2017 |
Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson's disease model by inhibiting microglial M1 polarization.
Topics: Animals; Locus Coeruleus; Male; Maneb; Mice; Microglia; NADPH Oxidases; Neurons; Neuroprotective Agents; Paraquat; Parkinson Disease, Secondary; STAT1 Transcription Factor; STAT3 Transcription Factor; Taurine | 2018 |
Taurine protects dopaminergic neurons in a mouse Parkinson's disease model through inhibition of microglial M1 polarization.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Gait; Gene Expression; Male; Maneb; Mice; Mice, Inbred C57BL; Microglia; NADPH Oxidase 2; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Paraquat; Parkinson Disease, Secondary; Signal Transduction; Taurine | 2018 |
NFE2L2, PPARGC1α, and pesticides and Parkinson's disease risk and progression.
Topics: Aged; Aged, 80 and over; Environmental Exposure; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Male; Maneb; Middle Aged; NF-E2-Related Factor 2; Paraquat; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pesticides; Polymorphism, Single Nucleotide; Risk Factors | 2018 |
Paraquat and Maneb Exposure Alters Rat Neural Stem Cell Proliferation by Inducing Oxidative Stress: New Insights on Pesticide-Induced Neurodevelopmental Toxicity.
Topics: Animals; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Herbicides; Maneb; Neural Stem Cells; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Pesticides; Rats, Sprague-Dawley | 2018 |
NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis.
Topics: Animals; Cell Line, Tumor; Dopaminergic Neurons; Ferroptosis; Fungicides, Industrial; Herbicides; Humans; Male; Maneb; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nerve Degeneration; Paraquat; Random Allocation | 2019 |
Early Postnatal Exposure to Paraquat and Maneb in Mice Increases Nigrostriatal Dopaminergic Susceptibility to a Re-challenge with the Same Pesticides at Adulthood: Implications for Parkinson's Disease.
Topics: Age Factors; Animals; Cell Count; Central Nervous System Sensitization; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Male; Maneb; Mice; Motor Skills; Paraquat; Pars Compacta; Tyrosine 3-Monooxygenase | 2020 |
Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson's disease.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Cell Proliferation; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Inflammation Mediators; Male; Maneb; Maze Learning; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Pars Compacta; Phagocytosis; Poloxamer; Recognition, Psychology; Synapses | 2020 |
Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model.
Topics: Adrenergic Neurons; Animals; CD11b Antigen; Disease Models, Animal; Inflammasomes; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinsonian Disorders; Pesticides | 2020 |
The protective function of taurine on pesticide-induced permanent neurodevelopmental toxicity in juvenile rats.
Topics: Animals; Hippocampus; Male; Maneb; Neurodevelopmental Disorders; Neurons; Paraquat; Rats; Rats, Sprague-Dawley; Signal Transduction; Taurine | 2021 |
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiparkinson Agents; Disease Models, Animal; Dopaminergic Neurons; Glyburide; Inflammasomes; Lipid Peroxidation; Male; Maneb; Mice, Inbred C57BL; Microglia; Motor Activity; NADPH Oxidase 2; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Paraquat; Parkinsonian Disorders | 2021 |
Autonomous regulation of inducible nitric oxide synthase and cytochrome P450 2E1-mediated oxidative stress in maneb- and paraquat-treated rat polymorphs.
Topics: Animals; Cytochrome P-450 CYP2E1; Maneb; Neutrophils; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Rats | 2021 |
Phenolic-rich extract of avocado Persea americana (var. Colinred) peel blunts paraquat/maneb-induced apoptosis through blocking phosphorylation of LRRK2 kinase in human nerve-like cells.
Topics: Apoptosis; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Maneb; Oxidative Stress; Paraquat; Persea; Phosphorylation; Plant Extracts | 2022 |
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis.
Topics: alpha-Synuclein; Animals; Environmental Pollutants; Fungicides, Industrial; Humans; Maneb; Metabolomics; Mice; Neuroblastoma; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Phenylalanine; Proteomics; Tryptophan | 2022 |
Cyclooxygenase-2 activates the free radical-mediated apoptosis of polymorphonuclear leukocytes in the maneb- and paraquat-intoxicated rats.
Topics: Adenosine Diphosphate; Animals; Apoptosis; Caspase 3; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytochromes c; Free Radicals; Humans; JNK Mitogen-Activated Protein Kinases; Lipid Peroxides; Maneb; Neutrophils; NF-kappa B; Oxidative Stress; Paraquat; Pesticides; Rats; Ribose; Superoxide Dismutase | 2022 |
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase-NLRP3 inflammasome axis-dependent microglial activation.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Inflammasomes; Integrins; Macrophage-1 Antigen; Macrophages; Maneb; Memory Disorders; Mice; Microglia; NADPH Oxidases; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinson Disease | 2023 |