Page last updated: 2024-08-21

paraquat and allopurinol

paraquat has been researched along with allopurinol in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (28.57)	18.7374
1990's	13 (30.95)	18.2507
2000's	8 (19.05)	29.6817
2010's	9 (21.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Iwasaki, K; Kato, R; Noguchi, H	2
Carlson, EJ; Epstein, CJ; Epstein, LB; Huang, TT	1
Kitazawa, Y; Matsubara, M; Takeyama, N; Tanaka, T	1
Anderson, BO; Beehler, CJ; Leff, JA; Repine, JE; Terada, LS; Waintrub, ML	1
Hirano, T; Hirobe, M; Nagano, T	1
Monteiro, HP; Vile, GF; Winterbourn, CC	1
Ishidate, M; Sawada, M; Sofuni, T	1
Alexander, NM; Bagnell, R; Hale, B; Kelner, MJ	1
Sutton, HC; Winterbourn, CC	2
Grichting, G; Jornot, L; Junod, AF	1
Dull, BJ; Hotchkiss, JH	1
Winterbourn, CC	2
Arai, T; Iizuka, I; Kojima, S; Kubota, K; Mori, H; Ona, S	1
Chu, CY; Huang, JM; Shiow, SJ; Tseng, TH; Wang, CJ	1
Absood, A; Berisha, H; Foda, HD; Pakbaz, H; Said, SI	1
Kawamoto, K; Sakai, M; Tanaka, T; Yamagami, K	1
Thomas, C; Vile, GF; Winterbourn, CC	1
Tanaka, R	1
Kitazawa, Y; Sakai, M; Takeyama, N; Tanaka, T; Yamagami, K	1
Dunn, KL; Farrant, JL; Gorringe, AR; Kroll, JS; Langford, PR; Reddin, KM; Wilks, KE	1
Iwakawa, S; Komada, F; Nishiguchi, K; Okumura, K; Tanigawara, Y	1
Keilhoff, G; Noack, H; Possel, H; Rethfeldt, C; Wolf, G	1
Berisha, HI; Pakbaz, H; Raza, S; Said, SI	1
Arita, Y; Davis, JM; Franek, WR; Horowitz, S; Kazzaz, JA; Koo, HC; Li, Y; Mantell, AS; Mantell, LL; Scott, W; Stansberry, L	1
Al-Ibraheem, J; Benov, L	1
Coleman, S; Sommer, D; Stemmer, PM; Swanson, SA	1
Fuentes, JM; González-Polo, RA; Morán, JM; Niso, M; Rodríguez-Martín, A; Soler, G	1
Adamus, J; Celińska, J; Gebicki, J; Marcinek, A; Rybak, M; Zielonka, J	1
do Nascimento, NC; e Silva, AC; Fett-Neto, AG; Fragoso, V; Moura, DJ; Richter, MF; Saffi, J	1
Lv, G; Zhang, J; Zhao, Y	1
Kachroo, A; Schwarzschild, MA	1
Chan, HM; Mailloux, RJ; Yumvihoze, E	1
Kumar, V; Singh, C; Singh, D	1
Ahmed, AAE; Ahmed, MAE; El Morsy, EM	1
Becker, DF; Becker, SM; Christgen, SL	1

Other Studies

42 other study(ies) available for paraquat and allopurinol

Article	Year
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Stimulatory effect of FMN and methyl viologen on cytochrome P-450 dependent reduction of tertiary amine N-oxide. Biochemical and biophysical research communications, 1976, Sep-07, Volume: 72, Issue:1 Topics: Amines; Animals; Cytochrome P-450 Enzyme System; Flavin Mononucleotide; Imipramine; Kinetics; Male; Microsomes, Liver; NADP; Oxides; Paraquat; Rats; Xanthine Oxidase	1976
Reduction of tertiary amine N-oxides by cytochrome P-450. Mechanism of the stimulatory effect of flavins and methyl viologen. Molecular pharmacology, 1978, Volume: 14, Issue:4 Topics: Amines; Animals; Cytochrome P-450 Enzyme System; Flavin Mononucleotide; Flavins; In Vitro Techniques; Male; Microsomes, Liver; NADP; Oxides; Oxidoreductases; Paraquat; Rats; Stimulation, Chemical; Xanthine Oxidase	1978
The role of superoxide anions in the establishment of an interferon-alpha-mediated antiviral state. Free radical research communications, 1992, Volume: 17, Issue:1 Topics: Allopurinol; Cell Survival; Fibroblasts; HeLa Cells; Humans; Interferon Type I; Paraquat; Recombinant Proteins; Superoxide Dismutase; Superoxides; Transfection	1992
The role of xanthine oxidase in paraquat intoxication. Archives of biochemistry and biophysics, 1991, Volume: 288, Issue:1 Topics: Animals; Cytochrome c Group; In Vitro Techniques; Lung; Male; Oxypurinol; Paraquat; Rats; Rats, Inbred Strains; Superoxides; Thiobarbiturates; Tungsten; Xanthine Dehydrogenase; Xanthine Oxidase	1991
Xanthine oxidase is increased and contributes to paraquat-induced acute lung injury. Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:4 Topics: Albumins; Animals; Lung; Lung Diseases; Male; Paraquat; Rats; Rats, Inbred Strains; Tungsten; Xanthine Dehydrogenase; Xanthine Oxidase	1990
Superoxide dismutase mimics based on iron in vivo. The Journal of biological chemistry, 1989, Jun-05, Volume: 264, Issue:16 Topics: Chelating Agents; Cytochrome c Group; Enzyme Induction; Escherichia coli; Ethylenediamines; Iron; Oxidation-Reduction; Paraquat; Superoxide Dismutase; Superoxides; Xanthine Oxidase	1989
An iron chelator is not required for reductive iron release from ferritin by radical generating systems. Free radical research communications, 1989, Volume: 7, Issue:1 Topics: Animals; Ascorbic Acid; Barbiturates; Catalase; Chelating Agents; Ferritins; Free Radicals; Hypoxanthines; In Vitro Techniques; Iron; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Paraquat; Rats; Rats, Inbred Strains; Xanthine Oxidase	1989
Induction of chromosomal aberrations in active oxygen-generating systems. II. A study with hydrogen peroxide-resistant cells in culture. Mutation research, 1988, Volume: 197, Issue:1 Topics: Animals; Cell Line; Chromosome Aberrations; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Glutathione Peroxidase; Glutathione Reductase; Hydrogen Peroxide; Kinetics; Paraquat; Superoxides; Xanthine Oxidase	1988
Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins. Archives of biochemistry and biophysics, 1988, May-01, Volume: 262, Issue:2 Topics: Cytochrome Reductases; Free Radicals; Heme; Methylene Blue; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat; Substrate Specificity; Superoxides; Xanthine Oxidase	1988
Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction. Archives of biochemistry and biophysics, 1986, Volume: 244, Issue:1 Topics: Catalysis; Deoxyribose; Ferredoxin-NADP Reductase; Formates; Free Radicals; Gamma Rays; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Oxidation-Reduction; Oxygen; Paraquat; Superoxides; Xanthine Oxidase	1986
Comparative study on the selenium- and N-acetylcysteine-related effects on the toxic action of hyperoxia, paraquat and the enzyme reaction hypoxanthine-xanthine oxidase in cultured endothelial cells. Agents and actions, 1987, Volume: 22, Issue:1-2 Topics: Acetylcysteine; Animals; Aorta, Thoracic; DNA; Endothelium, Vascular; In Vitro Techniques; Oxygen; Paraquat; Selenium; Selenomethionine; Swine; Xanthine Oxidase	1987
Activated oxygen and mammalian nitrate biosynthesis. Carcinogenesis, 1984, Volume: 5, Issue:9 Topics: Ammonia; Animals; In Vitro Techniques; Liver; Male; Nitrates; Paraquat; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine Oxidase	1984
Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence. Archives of biochemistry and biophysics, 1984, Nov-15, Volume: 235, Issue:1 Topics: Anaerobiosis; Chemical Phenomena; Chemistry; Deoxyribose; Edetic Acid; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oxygen; Paraquat; Pentetic Acid; Superoxide Dismutase; Xanthine Oxidase	1984
The reaction of hemoglobin with paraquat radicals in the presence and absence of O2. Biochemistry international, 1983, Volume: 7, Issue:1 Topics: Aerobiosis; Hemoglobins; Humans; Kinetics; Methemoglobin; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Paraquat; Spectrophotometry; Superoxide Dismutase; Xanthine Oxidase	1983
Production of hydroxyl radicals from paraquat radicals and H2O2. FEBS letters, 1981, Jun-15, Volume: 128, Issue:2 Topics: Chelating Agents; Free Radicals; Hydrogen Peroxide; Hydroxides; Iron; Paraquat; Structure-Activity Relationship; Superoxide Dismutase; Xanthine Oxidase	1981
Antioxidative activity of 5,6,7,8-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes. Free radical research, 1995, Volume: 23, Issue:5 Topics: Animals; Antioxidants; Biopterins; Cell Survival; Cells, Cultured; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxides; Liver; Luminescent Measurements; Macrophages; Male; Paraquat; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines	1995
Crocetin protects against oxidative damage in rat primary hepatocytes. Cancer letters, 1995, Oct-20, Volume: 97, Issue:1 Topics: Animals; Antioxidants; Carotenoids; Cells, Cultured; DNA Damage; DNA Repair; Lipid Peroxides; Liver; Male; Paraquat; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Vitamin A; Xanthine Oxidase	1995
Nitric oxide mediates oxidant tissue injury caused by paraquat and xanthine oxidase. Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723 Topics: Animals; Arginine; Guinea Pigs; In Vitro Techniques; Lung Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Paraquat; Rats; Xanthine; Xanthine Oxidase; Xanthines	1994
Tungsten modulates the toxicity of paraquat for epithelial cells. Human cell, 1993, Volume: 6, Issue:4 Topics: Animals; Cell Survival; Cells, Cultured; Dogs; Epithelial Cells; L-Lactate Dehydrogenase; Male; Paraquat; Tungsten; Xanthine Oxidase	1993
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction. Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10 Topics: Ascorbic Acid; Chelating Agents; Deoxyribose; Dimethyl Sulfoxide; Doxorubicin; Edetic Acid; Ethylenediamines; Ferric Compounds; Glycine; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Paraquat; Razoxane; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase	1993
Effects of pentoxifylline on active oxygen-induced sister-chromatid exchange. The Journal of toxicological sciences, 1995, Volume: 20, Issue:4 Topics: Animals; Cricetinae; Cricetulus; Free Radical Scavengers; Paraquat; Pentoxifylline; Sister Chromatid Exchange; Superoxides; Xanthine Oxidase	1995
Xanthine oxidase mediates paraquat-induced toxicity on cultured endothelial cell. Pharmacology & toxicology, 1995, Volume: 77, Issue:1 Topics: Allopurinol; Animals; Cattle; Cell Division; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Female; Herbicides; L-Lactate Dehydrogenase; Oxygen; Paraquat; Pulmonary Artery; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tungsten; Xanthine Dehydrogenase; Xanthine Oxidase	1995
Periplasmic superoxide dismutase in meningococcal pathogenicity. Infection and immunity, 1998, Volume: 66, Issue:1 Topics: Alleles; Animals; Artificial Gene Fusion; Bacterial Proteins; Cloning, Molecular; Copper; Cytosol; DNA, Bacterial; Gene Expression; Host-Parasite Interactions; Meningococcal Infections; Mice; Neisseria meningitidis; Paraquat; Periplasm; Reactive Oxygen Species; Recombination, Genetic; Sequence Analysis, DNA; Superoxide Dismutase; Virulence; Xanthine; Xanthine Oxidase; Zinc	1998
Effects of secretable SOD delivered by genetically modified cells on xanthine/xanthine oxidase and paraquat-induced cytotoxicity in vitro. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:8 Topics: Animals; Base Sequence; Cell Line; Culture Media, Conditioned; DNA Primers; Humans; Oxidative Stress; Paraquat; Rats; Recombinant Proteins; Superoxide Dismutase; Transfection; Xanthine; Xanthine Oxidase	1999
Peroxynitrite mediated damage and lowered superoxide tolerance in primary cortical glial cultures after induction of the inducible isoform of NOS. Glia, 1999, Volume: 28, Issue:1 Topics: Animals; Animals, Newborn; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Citrate (si)-Synthase; Enzyme Induction; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Neuroglia; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidants; Paraquat; Rats; Rats, Wistar; Superoxides; Xanthine Oxidase	1999
NMDA receptor activation: critical role in oxidant tissue injury. Free radical biology & medicine, 2000, Apr-15, Volume: 28, Issue:8 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guinea Pigs; Neurotoxins; Oxidants; Oxidative Stress; Paraquat; Pulmonary Edema; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Xanthine Oxidase	2000
Hyperoxia inhibits oxidant-induced apoptosis in lung epithelial cells. The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1 Topics: Antioxidants; Apoptosis; Cytochrome c Group; Epithelial Cells; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hydrogen Peroxide; I-kappa B Kinase; In Situ Nick-End Labeling; Lung; NF-kappa B; Oxidants; Oxygen; Paraquat; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthine Oxidase	2001
Glycerol metabolism in superoxide dismutase-deficient Escherichia coli. Free radical research, 2001, Volume: 35, Issue:6 Topics: Escherichia coli; Glycerol; Glycerol Kinase; Paraquat; Superoxide Dismutase; Time Factors; Xanthine Oxidase	2001
Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress. Archives of biochemistry and biophysics, 2002, Aug-15, Volume: 404, Issue:2 Topics: Animals; Calcineurin; Enzyme Activation; Enzyme Activators; Humans; Hydrogen Peroxide; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Oxidants; Oxidative Stress; Paraquat; Phosphoprotein Phosphatases; Rabbits; Reducing Agents; Superoxides; Tumor Cells, Cultured; Xanthine Oxidase	2002
Paraquat-induced apoptotic cell death in cerebellar granule cells. Brain research, 2004, Jun-18, Volume: 1011, Issue:2 Topics: Allopurinol; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Herbicides; In Situ Nick-End Labeling; Male; Mitochondria; Models, Biological; Neurons; Paraquat; Piperazines; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Vitamin E	2004
Effect of heparin on viologen-stimulated enzymatic NADH depletion. Chemical research in toxicology, 2006, Volume: 19, Issue:5 Topics: Cytochrome c Group; Diquat; Heparin; NADP; Oxidation-Reduction; Paraquat; Superoxides; Xanthine Oxidase	2006
Antioxidant and antimutagenic properties of the monoterpene indole alkaloid psychollatine and the crude foliar extract of Psychotria umbellata Vell. Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:3 Topics: Antimutagenic Agents; Antioxidants; Cell Division; Cell Proliferation; Culture Media; Glycosides; Herbicides; Hydrogen Peroxide; Indole Alkaloids; Oxidants; Paraquat; Plant Extracts; Plant Leaves; Psychotria; Reactive Oxygen Species; Saccharomyces cerevisiae; Xanthine Oxidase	2008
The significance of serum xanthine oxidase and oxidation markers in acute paraquat poisoning in humans. Clinical biochemistry, 2011, Volume: 44, Issue:2-3 Topics: Humans; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Paraquat; Superoxide Dismutase; Xanthine Oxidase	2011
Allopurinol reduces levels of urate and dopamine but not dopaminergic neurons in a dual pesticide model of Parkinson's disease. Brain research, 2014, May-14, Volume: 1563 Topics: Allopurinol; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Enzyme Inhibitors; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease; Pesticides; Uric Acid	2014
Superoxide anion radical (O2(-)) degrades methylmercury to inorganic mercury in human astrocytoma cell line (CCF-STTG1). Chemico-biological interactions, 2015, Sep-05, Volume: 239 Topics: Astrocytoma; Cell Death; Cell Line, Tumor; Central Nervous System Neoplasms; Humans; Hydrogen Peroxide; Mercury; Methylmercury Compounds; Oxidative Stress; Paraquat; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase	2015
IFN-γ regulates xanthine oxidase-mediated iNOS-independent oxidative stress in maneb- and paraquat-treated rat polymorphonuclear leukocytes. Molecular and cellular biochemistry, 2017, Volume: 427, Issue:1-2 Topics: Animals; Interferon-gamma; Male; Maneb; Neutrophils; Nitric Oxide Synthase Type II; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Xanthine Oxidase	2017
Protective effects of febuxostat against paraquat-induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades. Life sciences, 2019, Mar-15, Volume: 221 Topics: Acute Lung Injury; Animals; beta Catenin; Febuxostat; Inflammation; Lung; Lung Injury; Male; Oxidative Stress; Paraquat; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Edema; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Xanthine Oxidase	2019
Methods for determining the reduction potentials of flavin enzymes. Methods in enzymology, 2019, Volume: 620 Topics: Benzyl Viologen; Enzyme Assays; Flavins; Flavoproteins; Indicators and Reagents; Oxidation-Reduction; Paraquat; Potentiometry; Xanthine; Xanthine Oxidase	2019