paraoxon has been researched along with tabun in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Dacre, JC; Henderson, JD; Higgins, RJ; Wilson, BW | 1 |
| Maxwell, DM | 1 |
| Eldefrawi, AT; Eldefrawi, ME; Silveira, CL | 1 |
| Forster, JS; Hammond, PS | 1 |
| Pavković, E; Radić, Z; Reiner, E; Simeon, V | 1 |
| Broomfield, CA; Platteborze, PL | 1 |
| Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K | 2 |
| Kellar, KJ | 1 |
| Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V | 2 |
| Dohnal, V; Dolezal, M; Gunn-Moore, F; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V | 1 |
| Dohnal, V; Jun, D; Kuca, K; Kucera, J; Musilek, K; Opletalova, V | 1 |
| Busić, V; Gaso-Sokac, D; Katalinić, M; Kovac, S; Kovarik, Z | 1 |
| Binder, J; Holas, O; Jun, D; Jung, YS; Katalinić, M; Kovarik, Z; Kuca, K; Musilova, L; Sinko, G | 1 |
| Berend, S; Katalinić, M; Kopjar, N; Kovarik, Z; Lovrić, J; Lucić Vrdoljak, A; Mesić, M; Radić, B; Rast, S; Želježić, D | 1 |
| Koller, M; Thiermann, H; Wille, T; Worek, F | 1 |
| Amitai, G; Barry Sharpless, K; Berend, S; Fokin, VV; Garcia, E; Kovarik, Z; Radić, Z; Sit, RK; Taylor, P; Zhang, L | 1 |
| Bahnson, BJ; Cerasoli, DM; Kirby, SD; Norris, JR; Richard Smith, J | 1 |
| Atanasov, VN; Dishovsky, C; Petrova, I | 1 |
| Kuca, K; Musilek, K; Thiermann, H; Wille, T; Winter, M; Worek, F | 1 |
| Box, K; Ceckova, M; Dolezal, R; Gorecki, L; Hepnarova, V; Hrabinova, M; Jankockova, J; Jost, P; Jun, D; Kobrlova, T; Korabecny, J; Kuca, K; Malinak, D; Musilek, K; Nepovimova, E; Nguyen, TD; Outhwaite, B; Pavek, P; Pham, NL; Psotka, M; Sorf, A; Soukup, O | 1 |
| Bernal, K; Brazzolotto, X; Bzdrenga, J; Chantegreil, F; Nachon, F; Trenet, E | 1 |
23 other study(ies) available for paraoxon and tabun
| Article | Year |
|---|---|
Neurotoxicity of acute and repeated treatments of tabun, paraoxon, diisopropyl fluorophosphate and isofenphos to the hen.
Topics: Acetylcholinesterase; Animals; Body Weight; Butyrylcholinesterase; Chickens; Cholinesterase Inhibitors; Cholinesterases; Creatine Kinase; Female; Injections, Intramuscular; Insecticides; Isoflurophate; Motor Activity; Organophosphates; Organothiophosphorus Compounds; Paraoxon; Spinal Cord; Tibial Nerve | 1992 |
The specificity of carboxylesterase protection against the toxicity of organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Brain; Carboxylic Ester Hydrolases; In Vitro Techniques; Kinetics; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman; Substrate Specificity | 1992 |
Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases.
Topics: Animals; Cholinesterase Inhibitors; Dioxolanes; Dose-Response Relationship, Drug; Echothiophate Iodide; Insecticides; Male; Myocardium; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sarin; Soman; Tritium | 1990 |
A microassay-based procedure for measuring low levels of toxic organophosphorus compounds through acetylcholinesterase inhibition.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Reference Standards; Soman; Spectrophotometry | 1989 |
Differentiation of esterases reacting with organophosphorus compounds.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aryldialkylphosphatase; Cholinesterase Inhibitors; Cholinesterases; Edetic Acid; Esterases; Female; Humans; Hydrolysis; Kinetics; Male; Middle Aged; Naphthaleneacetic Acids; Nitrophenols; Organophosphates; Organophosphorus Compounds; Paraoxon; Phenylacetates; Phosphoric Monoester Hydrolases; Physostigmine; Sensitivity and Specificity; Substrate Specificity; Tetraisopropylpyrophosphamide; Thiocholine | 1993 |
Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni).
Topics: Animals; Baculoviridae; Butyrylcholinesterase; Cells, Cultured; Cholinesterase Inhibitors; COS Cells; Glycosylation; Humans; Hydrolysis; Larva; Lepidoptera; Organophosphates; Organophosphorus Compounds; Paraoxon; Protein Engineering; Recombinant Proteins; Sarin; Soman | 2000 |
Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Cholinesterase Inhibitors; Nitriles; Organophosphates; Paraoxon; Pyridinium Compounds | 2006 |
Overcoming inhibitions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors | 2006 |
Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Organophosphates; Oximes; Paraoxon; Pyridinium Compounds | 2007 |
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Organophosphates; Oximes; Paraoxon; Rats; Structure-Activity Relationship | 2007 |
Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Chemical Warfare Agents; Chemistry; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Drug Design; Models, Chemical; Obidoxime Chloride; Organophosphates; Paraoxon; Pesticides; Pyridinium Compounds; Salts; Xylenes | 2007 |
Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Carbamates; Cholinesterase Inhibitors; Humans; Organophosphates; Oximes; Paraoxon; Pyridinium Compounds | 2008 |
Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators; Models, Biological; Molecular Structure; Organophosphates; Paraoxon; Pyridinium Compounds; Rats; Stereoisomerism; Structure-Activity Relationship | 2008 |
Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Humans; Organophosphates; Oximes; Paraoxon; Vitamin B 6 | 2010 |
Pseudo-catalytic scavenging: searching for a suitable reactivator of phosphorylated butyrylcholinesterase.
Topics: Acetylcholinesterase; Biocatalysis; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Discovery; Enzyme Activation; Humans; Inactivation, Metabolic; Models, Molecular; Organophosphates; Oximes; Paraoxon; Phosphorylation | 2010 |
A conjugate of pyridine-4-aldoxime and atropine as a potential antidote against organophosphorus compounds poisoning.
Topics: Acetylcholinesterase; Adult; Animals; Antidotes; Atropine Derivatives; Cell Death; Cell Survival; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Assays; Erythrocytes; Humans; Lymphocytes; Male; Mice; Organophosphate Poisoning; Organophosphates; Paraoxon; Pralidoxime Compounds; Soman | 2011 |
Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase--Structure-activity relationships.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Kinetics; Organophosphates; Organophosphorus Compounds; Oximes; Paraoxon; Structure-Activity Relationship | 2012 |
Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates.
Topics: Acetamides; Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Evaluation, Preclinical; GPI-Linked Proteins; Humans; Kinetics; Models, Molecular; Organophosphates; Organophosphorus Compounds; Oximes; Paraoxon; Sarin | 2013 |
Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents.
Topics: Amino Acid Substitution; Antidotes; Aryldialkylphosphatase; Catalytic Domain; Chemical Warfare Agents; Humans; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Protein Engineering; Recombinant Proteins; Sarin; Soman; Substrate Specificity | 2013 |
In vitro investigation of efficacy of new reactivators on OPC inhibited rat brain acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dichlorvos; Drug Evaluation, Preclinical; GPI-Linked Proteins; Male; Organophosphates; Organophosphorus Compounds; Oximes; Paraoxon; Rats; Rats, Wistar; Structure-Activity Relationship | 2013 |
Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; GPI-Linked Proteins; Humans; Kinetics; Molecular Structure; Organophosphates; Organophosphorus Compounds; Oximes; Paraoxon; Pyridinium Compounds; Structure-Activity Relationship | 2016 |
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
Topics: Animals; Antidotes; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Paraoxon; Rats; Sarin | 2018 |
A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study.
Topics: Amino Acids; Crystallography, X-Ray; Esterases; Kinetics; Nerve Agents; Organophosphates; Organophosphorus Compounds; Paraoxon; Planctomycetales; Planctomycetes; Sarin | 2021 |