Page last updated: 2024-08-21

paracymethadol and methadone

paracymethadol has been researched along with methadone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khazan, N; Steinfels, GF; Young, GA1
Gibson, A; Vernadakis, A1
DePace, A; Mulé, SJ; Verebey, K1
Kuwahara, MD; Sparber, SB2
Freeman, RW; Harbison, RD; James, RC1
Bartolomeo, JG; Bates, TR; Bloch, R; Misra, AL; Mulé, SJ1
Finkle, BS; Lichtblau, L; Sparber, SB1
Harbison, RD; James, RC1
Jasinski, DR; Vaupel, DB1
Alburges, ME; Collins, JM; Moody, DE; Parker, RJ; Strong, JM1
Fiellin, DA; O'Connor, PG1
Bochner, F; Newcombe, DAL; Somogyi, AA; White, JM1

Reviews

1 review(s) available for paracymethadol and methadone

ArticleYear
Pharmacologic treatment of heroin-dependent patients.
    Annals of internal medicine, 2000, Jul-04, Volume: 133, Issue:1

    Topics: Analgesics, Opioid; Buprenorphine; Counseling; Heroin Dependence; Humans; Mental Disorders; Methadone; Methadyl Acetate; Naltrexone; Narcotic Antagonists; Physician's Role; Substance Withdrawal Syndrome

2000

Trials

1 trial(s) available for paracymethadol and methadone

ArticleYear
Impaired psychomotor function and plasma methadone and levo-alpha-acetylmethadol (LAAM) concentrations in opioid-substitution patients.
    Experimental and clinical psychopharmacology, 2017, Volume: 25, Issue:3

    Topics: Adult; Drug Tolerance; Female; Humans; Male; Methadone; Methadyl Acetate; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Psychomotor Performance; Time Factors; Young Adult

2017

Other Studies

11 other study(ies) available for paracymethadol and methadone

ArticleYear
Opioid self-administration and REM sleep EEG power spectra.
    NIDA research monograph, 1979, Volume: 27

    Topics: Animals; Electroencephalography; Female; Methadone; Methadyl Acetate; Morphine; Narcotics; Rats; Self Administration; Sleep, REM

1979
Neurotoxicity of opiates during brain development: in vivo and in vitro studies.
    Progress in clinical and biological research, 1985, Volume: 163C

    Topics: Abnormalities, Drug-Induced; Animals; Binding Sites; Brain; Cells, Cultured; Chick Embryo; Etorphine; In Vitro Techniques; Methadone; Methadyl Acetate; Neurons; Receptors, Opioid; Tritium

1985
Quantitation of l-alpha-acetylmethadol and its metabolites in human serum by capillary gas-liquid chromatography and nitrogen detection.
    Journal of chromatography, 1985, Oct-11, Volume: 343, Issue:2

    Topics: Chromatography, Gas; Drug Stability; Humans; Methadone; Methadyl Acetate; Time Factors

1985
Continuous exposure of the chick embryo to l-alpha-noracetylmethadol does not alter brain protein or nucleic acid content.
    Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:1

    Topics: Animals; Brain; Chick Embryo; DNA; Methadone; Methadyl Acetate; Nerve Tissue Proteins; Organ Size; RNA

1981
Opiate withdrawal increases ornithine decarboxylase activity which is otherwise unaltered in brains of dependent chicken fetuses.
    Life sciences, 1983, Jan-31, Volume: 32, Issue:5

    Topics: Animals; Brain; Carboxy-Lyases; Chick Embryo; Humans; Methadone; Methadyl Acetate; Naloxone; Ornithine Decarboxylase; Substance Withdrawal Syndrome

1983
L-alpha-acetylmethadol-induced tissue alterations in mice.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:1

    Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Glutathione; Kidney; Liver; Male; Methadone; Methadyl Acetate; Methylcholanthrene; Mice; Mice, Inbred ICR; Necrosis; Phenobarbital; Time Factors

1984
Pharmacokinetics and metabolism of l-alpha-[O,O'-3H2]-acetyl normethadol (nor-LAAM), the active metabolite of LAAM, in acutely and chronically treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:3

    Topics: Administration, Oral; Animals; Behavior, Animal; Biological Availability; Biotransformation; Haplorhini; Injections, Intravenous; Kinetics; Macaca mulatta; Methadone; Methadyl Acetate; Time Factors

1980
Cumulation of active metabolites of levo-alpha-acetylmethadol in the rat fetus and neonate.
    Life sciences, 1982, Jan-18, Volume: 30, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Female; Fetus; Maternal-Fetal Exchange; Methadone; Methadyl Acetate; Pregnancy; Rats; Rats, Inbred Strains

1982
Hepatic glutathione and hepatotoxicity: effects of cytochrome P-450 complexing compounds SKF 525-A, L-alpha acetylmethadol (LAAM), norLAAM, and piperonyl butoxide.
    Biochemical pharmacology, 1982, May-15, Volume: 31, Issue:10

    Topics: Alanine Transaminase; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Glutathione; Liver; Male; Mesocricetus; Methadone; Methadyl Acetate; Mice; Mixed Function Oxygenases; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains

1982
l-alpha-Acetylmethadol, l-alpha-acetyl-N-normethadol and l-alpha-acetyl-N,N-dinormethadol: comparisons with morphine and methadone in suppression of the opioid withdrawal syndrome in the dog.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: Analgesics, Opioid; Animals; Dogs; Dose-Response Relationship, Drug; Methadone; Methadyl Acetate; Morphine; Opioid-Related Disorders; Substance Withdrawal Syndrome

1997
The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:12

    Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylamines; DNA, Complementary; Enzyme Inhibitors; Humans; Isoenzymes; Methadone; Methadyl Acetate; Microsomes, Liver; Mixed Function Oxygenases; Substrate Specificity

1997