papaverine and promethazine

papaverine has been researched along with promethazine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's0 (0.00)18.2507
2000's4 (11.43)29.6817
2010's6 (17.14)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Golovko, NG1
Brodde, OE; Reinhardt, D; Schmidt, U; Schümann, HJ1
Chan, YH; Curtis-Prior, PB; Jenner, M; McColl, I1
Chakravarti, RN; Sachdeva, HS; Sachdeva, KC1
Kawakami, M; Matsuda, S; Takeda, H; Ueda, M1
Horn, W1
Schramm, H1
Bartsch, R; Femmer, K; Nowak, R; Stade, K1
Demay, D; Mancheron, D; Pellerin, F1
el-Asmar, MF; Ibrahim, SA; Ismail, M; Osman, OH1
Dundee, JW; Haslett, WH1
Gamble, WJ; Kumar, AE; LaFarge, CG; Manasek, FJ; Monroe, RG1
Bovill, JG; Clarke, RS; Dundee, JW; Moore, J; Pandit, SK1
Stapenhorst, K1
Bhargava, KC; Chakravarti, RN; Dhall, SR; Dutta, D1
Armstrong, R; Baskett, PJ1
Simpson, JM1
Johnstone, M1
MARIANI, L1
BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I1
WASILEWSKA, L1
BERGMANN, H1
AUCLAIR, M; THEVENOT, R1
Agretti, P; De Marco, G; Dimida, A; Ferrarini, E; Pinchera, A; Rodrìguez Gonzàlez, JC; Santini, F; Tonacchera, M; Vitti, P1
Baka, E; Kovács, M; Takácsné, NK; Völgyi, G1

Reviews

2 review(s) available for papaverine and promethazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Spasmolytics. 5].
    Pharmazeutische Praxis, 1967, Volume: 5

    Topics: Aniline Compounds; Animals; Atropine; Barbiturates; Benzoates; Esters; Humans; Isoquinolines; Khellin; Mandelic Acids; Muscles; Oxyphenonium; Papaverine; Promethazine; Propantheline; Pyrimidines; Quaternary Ammonium Compounds; Scopolamine; Sulfates; Tropanes

1967

Trials

3 trial(s) available for papaverine and promethazine

ArticleYear
Studies of drugs given before anaesthesia. XIV. Two benzodiazepine derivatives--chlordiazepoxide and diazepam.
    British journal of anaesthesia, 1968, Volume: 40, Issue:4

    Topics: Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Female; Humans; Injections, Intramuscular; Morphine; Papaverine; Placebos; Preanesthetic Medication; Promazine; Promethazine; Tranquilizing Agents

1968
Environmental temperature and response to premedicant drugs.
    Anaesthesia, 1970, Volume: 25, Issue:4

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Arteries; Atropine; Basal Metabolism; Bicarbonates; Carbon Dioxide; England; Female; Humans; Jamaica; Male; Meperidine; Middle Aged; Oxygen; Papaverine; Preanesthetic Medication; Promethazine; Scopolamine; Temperature; Tropical Climate

1970
The effects of sedation on the digital plethysmogram. A radiotelemetric study of haloperidol.
    Anaesthesia, 1967, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Anxiety; Blood Vessels; Drug Antagonism; Drug Synergism; Female; Fingers; Haloperidol; Halothane; Humans; Male; Meperidine; Middle Aged; Papaverine; Plethysmography; Preanesthetic Medication; Promethazine; Scopolamine; Thiopental

1967

Other Studies

30 other study(ies) available for papaverine and promethazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[Treatment of arterial occlusive diseases of the leg in the gangrenous stage].
    Khirurgiia, 1978, Issue:10

    Topics: Acetylcholine; Arteriosclerosis Obliterans; Ascorbic Acid; Diphenhydramine; Endarteritis; Glucose; Heparin; Humans; Infusions, Intra-Arterial; Leg; Lumbosacral Region; Opium; Papaverine; Procaine; Promethazine; Sympathectomy; Tetracyclines; Thiamine

1978
H1 - and H2-receptor mediated responses to histamine on contractility and cyclic AMP of atrial and papillary muscles from guinea-pig hearts.
    Agents and actions, 1977, Volume: 7, Issue:1

    Topics: Animals; Atrial Function; Burimamide; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Histamine; Male; Myocardial Contraction; Myocardium; Papaverine; Promethazine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2

1977
Effects of several preoperative medications on fat cell lipolysis, and activity of adipose tissue cyclic AMP phosphodiesterase.
    Experientia, 1979, Nov-15, Volume: 35, Issue:11

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Atropine; Diazepam; Lipid Mobilization; Male; Meperidine; Papaverine; Promethazine; Rats; Scopolamine

1979
Fat embolism: an experimental study (II). Evaluation of smooth muscle relaxants in its treatment.
    The American surgeon, 1969, Volume: 35, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Atropine; Electrocardiography; Embolism, Fat; Epinephrine; Ergotamine; Injections, Intravenous; Lipids; Lung; Muscles; Myocardium; Papaverine; Promethazine; Rabbits

1969
Depressor mechanism of synthetic ACTH (50022).
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:4

    Topics: Acetylcholine; Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Bradykinin; Cats; Depression, Chemical; Electrocardiography; Epinephrine; Heart Rate; In Vitro Techniques; Isoproterenol; Papaverine; Promethazine; Rabbits; Respiration

1970
[The modification of experimental ulcer in immobilized rats by different pharmacologic agents].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1968, Volume: 28, Issue:5

    Topics: Animals; Atropine; Autonomic Agents; Chlorpromazine; Cold Temperature; Estrogens; Female; Gastric Mucosa; Histamine H1 Antagonists; Humans; Immobilization; Kallikreins; Male; Neostigmine; Papaverine; Promethazine; Rats; Sex Factors; Statistics as Topic; Stomach; Stomach Ulcer; Stress, Psychological; Sympathomimetics; Tranquilizing Agents

1968
[Pharmacology of the new antihistaminic 9,9-dioxopromethazine (Prothanon)].
    Die Pharmazie, 1970, Feb-02, Volume: 25, Issue:2

    Topics: Abnormalities, Drug-Induced; Anesthetics, Local; Animals; Behavior, Animal; Blood Pressure; Bronchial Spasm; Cardiac Output; Carotid Arteries; Cats; Central Nervous System; Central Nervous System Stimulants; Conditioning, Classical; Croton Oil; Depression, Chemical; Drug Synergism; Edema; Embryo, Mammalian; Ergotamine; Ethanol; Female; Guinea Pigs; Heart Rate; Histamine H1 Antagonists; Ileum; Male; Mice; Mydriatics; Papaverine; Parasympatholytics; Promethazine; Proteins; Rabbits; Rats; Salivation; Serotonin Antagonists

1970
[Identification and determination of organic bases by ultraviolet spectrophotometry of their laurylsulfate and dioctylsulfosuccinate derivatives].
    Annales pharmaceutiques francaises, 1972, Volume: 30, Issue:6

    Topics: Alkaloids; Body Fluids; Chlorpromazine; Fatty Alcohols; Methods; Papaverine; Procaine; Promethazine; Sodium Dodecyl Sulfate; Spectrophotometry; Strychnine; Succinates; Surface-Active Agents; Ultraviolet Rays

1972
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
    Toxicon : official journal of the International Society on Toxinology, 1972, Volume: 10, Issue:4

    Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compounds; Kinins; Lysergic Acid Diethylamide; Methysergide; Muscle Contraction; ortho-Aminobenzoates; Papaverine; Pregnancy; Promethazine; Rats; Scorpions; Toluene; Tripelennamine; Uterus; Venoms

1972
Left ventricular performance and coronary flow after coronary embolization with plastic microspheres.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:8

    Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Coronary Circulation; Disease Models, Animal; Dogs; Elasticity; Extracorporeal Circulation; Heart Rate; Heart Ventricles; Myocardial Infarction; Myocardium; Nitroglycerin; Papaverine; Polystyrenes; Promethazine; Propranolol; Stress, Mechanical; Vascular Resistance

1971
Clinical studies of induction agents. 38. Effect of premedicants and supplements on ketamine anaesthesia.
    British journal of anaesthesia, 1971, Volume: 43, Issue:6

    Topics: Adult; Analgesics; Anesthesia; Atropine; Benperidol; Blood Pressure; Cyclohexanes; Diazepam; Dreams; Female; Fentanyl; Heart Rate; Humans; Hypertension; Ketamine; Meperidine; Papaverine; Pentobarbital; Preanesthetic Medication; Promethazine; Scopolamine; Surgical Procedures, Operative

1971
[Effects of some vasotonic pharmacons upon pulmonary circulation].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1969, Volume: 151, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Blood Pressure; Carbon Dioxide; Cats; Electrophysiology; Epinephrine; Female; Histamine; Isoproterenol; Light; Male; Norepinephrine; Papaverine; Promethazine; Pulmonary Circulation; Regional Blood Flow; Respiration; Vasoconstrictor Agents; Vasodilator Agents

1969
Therapeutic studies in experimental amniotic fluid embolism in rabbits.
    American journal of obstetrics and gynecology, 1970, Apr-15, Volume: 106, Issue:8

    Topics: Anaphylaxis; Animals; Atropine; Bronchial Spasm; Disease Models, Animal; Electrocardiography; Embolism, Amniotic Fluid; Female; Heart Conduction System; Humans; Isoproterenol; Papaverine; Pregnancy; Promethazine; Pulmonary Embolism; Rabbits

1970
Anaesthetic problems in multiple sclerosis. Are certain agents contraindicated?
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Adult; Amobarbital; Anesthesia; Anesthetics; Atropine; Female; Halothane; Humans; Levallorphan; Meperidine; Middle Aged; Morphine; Multiple Sclerosis; Nitrous Oxide; Oxygen; Papaverine; Preanesthetic Medication; Promethazine; Scopolamine; Thiopental

1970
[Drugs antagonistic to bradykinin].
    Bollettino della Societa italiana di biologia sperimentale, 1961, Dec-31, Volume: 37

    Topics: Anti-Allergic Agents; Atropine; Bradykinin; Chlorpromazine; Ergotamine; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Papaverine; Phenylbutazone; Promazine; Promethazine

1961
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
    Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental

1962
[A NEW COMPLEXOMETRIC METHOD FOR THE DETERMINATION OF ORGANIC BASES].
    Acta poloniae pharmaceutica, 1963, Volume: 20

    Topics: Chemistry, Pharmaceutical; Chlorpromazine; Imipramine; Papaverine; Promethazine; Research; Succinylcholine

1963
[SENSITIVITY CHANGES OF THE ISOLATED GUINEA PIG INTESTINE BY PREMEDICATION, ANESTHESIA AND SPASMOLYTICS].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1963, Volume: 18

    Topics: Aminopyrine; Anesthesia; Animals; Atropine; Barium; Bis-Trimethylammonium Compounds; Chlorides; Chlorpromazine; Chlorprothixene; Ether; Guinea Pigs; Intestines; Meperidine; Methantheline; Morphine; Neostigmine; Papaverine; Parasympatholytics; Pentobarbital; Phenothiazines; Promethazine; Quaternary Ammonium Compounds; Research; Scopolamine; Tubocurarine

1963
[TOXICOLOGY AND PHARMACOLOGY OF AN ORGANIC SOLVENT: DIMETHYL SULFOXIDE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Acetylcholine; Barium; Blood Pressure; Dimethyl Sulfoxide; Duodenum; Guinea Pigs; Histamine; Ileum; Kidney; Mice; Muscle, Smooth; Muscles; Nicotine; Papaverine; Pharmacology; Promethazine; Rats; Research; Serotonin; Solvents; Toxicology

1964
Study of potential inhibitors of thyroid iodide uptake by using CHO cells stably expressing the human sodium/iodide symporter (hNIS) protein.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:3

    Topics: 14-alpha Demethylase Inhibitors; Amphotericin B; Animals; Anti-Allergic Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Atropine; Biotin; Buspirone; CHO Cells; Cricetinae; Cricetulus; Econazole; Humans; Hydrocortisone; Iodides; Metronidazole; Muscarinic Antagonists; Papaverine; Perchlorates; Phosphodiesterase Inhibitors; Promethazine; Serotonin Receptor Agonists; Sulfadiazine; Symporters; Thiocyanates; Thyroid Gland

2011
[Good laboratory practice of equilibrium solubility measurement II. Study of pH-dependent solubility of ionizable compounds].
    Acta pharmaceutica Hungarica, 2011, Volume: 81, Issue:2

    Topics: Dibenzothiazepines; Hydrogen-Ion Concentration; Ions; Laboratories; Papaverine; Promethazine; Propafenone; Quetiapine Fumarate; Reproducibility of Results; Sodium Chloride; Solubility; Water

2011