papaverine and pentoxifylline

papaverine has been researched along with pentoxifylline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's4 (13.79)18.2507
2000's5 (17.24)29.6817
2010's8 (27.59)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, G; Ke, H; Kunz, S; Martinelli, S; Robinson, H; Seebeck, T; Wan, Y; Wang, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
de Esch, IJ; de Graaf, C; Jansen, C; Kanev, GK; Kooistra, AJ; Leurs, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hutten, H; Reichl, R; Vaupel, P1
Adil'khanov, SG; Il'in, SG; Koshkin, VM; Shestakov, VA; Zatevakhin, II1
Adil'khanov, SG; Antonova, NIu; Koshkin, VM1
Blaskó, G; Hermecz, I; Kapui, Z; Sarkadi, B; Szentmiklósi, P; Tardos, L1
Anderson, J; Ibe, BO; Kaapa, P; Raj, JU1
Ballet, F; Chazouillères, O; Chrétien, Y; Maillard, D; Marteau, P; Poupon, R; Rey, C1
Benazzo, M; Castelnuovo, P; Galioto, GB; Galioto, P; Mevio, E1
Morley, JE1
Hollister, LE1
Burleva, EP; Ermolaev, VL1
Adil'khanov, SG; Koshkin, VM; Sapozhnikov, VA; Sergeeva, NA; Terekhova, TV1
Argel, MI; Chiappe, GE; Chiappe, LE; Cingolani, HE; Grassi, AO; Vittone, L1
Herman, G; Mauduit, P; Rossignol, B1
Ermolaev, VL; Makarova, NP; Zavalskiĭ, II1
Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M1
Bakhritdinov, FSh; Karimov, ZZ; Trynkin, AV1
Cankaya, H; Içli, M; Kiriş, M; Kutluhan, A1
Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG1
Horvath, B; Kesmarky, G; Toth, K; Vekasi, J1
Ayan, F; Ersoy, YE; Himmetoglu, S1
Levine, LA1
Avon, C; Charles, O; Cortvrindt, R; Giorgetti, C; Hans, E; Lazdunski, P; Salzmann, J; Terriou, P1

Reviews

1 review(s) available for papaverine and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

28 other study(ies) available for papaverine and pentoxifylline

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors.
    The Journal of biological chemistry, 2012, Apr-06, Volume: 287, Issue:15

    Topics: Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Drug Design; Kinetics; Molecular Sequence Data; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sulfonamides; Surface Properties; Trypanosoma cruzi

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design.
    Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15

    Topics: Databases, Protein; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Models, Molecular; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Structure-Activity Relationship

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Influence of various vasodilatory drugs on the cerebral circulation in rabbits and rats.
    Bibliotheca anatomica, 1979, Issue:18

    Topics: Animals; Bencyclane; Carotid Artery, Internal; Cerebrovascular Circulation; Cinnarizine; Injections, Intra-Arterial; Nafronyl; Papaverine; Pentoxifylline; Piribedil; Rabbits; Rats; Vascular Resistance; Vasodilator Agents; Vincamine; Xanthinol Niacinate

1979
[Effect of papaverine and trental on hemostasis and rheologic properties of blood in acute arterial obstruction].
    Problemy gematologii i perelivaniia krovi, 1979, Volume: 24, Issue:12

    Topics: Acute Disease; Blood Viscosity; Hemostasis; Humans; Papaverine; Pentoxifylline; Theobromine; Thrombosis

1979
[Peripheral macro-and microcirculatory changes in acute arterial obstruction with papaverine and trental administration].
    Vestnik khirurgii imeni I. I. Grekova, 1979, Volume: 123, Issue:12

    Topics: Acute Disease; Arterial Occlusive Diseases; Blood Circulation; Drug Evaluation; Embolism; Hemodynamics; Humans; Microcirculation; Middle Aged; Papaverine; Pentoxifylline; Postoperative Complications; Theobromine; Thrombosis; Vascular Resistance

1979
Comparative studies of drotaverine--acephyllinate (Depogen) and pentoxifylline (Trental).
    Thrombosis research, 1992, Jun-15, Volume: 66, Issue:6

    Topics: Animals; Cell Aggregation; Drug Combinations; Drug Evaluation, Preclinical; Erythrocytes; Humans; Leukocytes; Papaverine; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 3; Rabbits; Theophylline

1992
Effect of pentoxifylline in rabbit pulmonary circulation: influence of age and vasomotor tone.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2

    Topics: Aging; Animals; Epoprostenol; Indomethacin; Papaverine; Pentoxifylline; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Pulmonary Circulation; Rabbits; Vascular Resistance; Vasoconstriction; Vasodilator Agents; Vasomotor System

1991
Protective effect of vasodilators on liver function after long hypothermic preservation: a study in the isolated perfused rat liver.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:6

    Topics: Animals; Bile; Hemodynamics; In Vitro Techniques; Liver; Liver Circulation; Liver Transplantation; Male; Organ Preservation; Organ Size; Papaverine; Pentoxifylline; Portal Vein; Rats; Rats, Inbred Strains; Reperfusion Injury; Taurocholic Acid; Theobromine; Time Factors; Vascular Resistance

1989
[A study using laser-Doppler velocimetry of modifications of the labyrinthine microcirculation induced by chemical and physical stimuli].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1989, Volume: 106, Issue:2

    Topics: Animals; Cochlea; Lasers; Microcirculation; Nafronyl; Noise; Papaverine; Pentoxifylline; Phenylephrine; Pyrrolidines; Rabbits; Vasodilator Agents

1989
Impotence in older men.
    Hospital practice (Office ed.), 1988, Apr-15, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Drug-Related Side Effects and Adverse Reactions; Erectile Dysfunction; Humans; Hypogonadism; Male; Papaverine; Pentoxifylline; Prostheses and Implants; Psychophysiologic Disorders; Vascular Diseases

1988
Alzheimer's disease. Is it worth treating?
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Aged; Alzheimer Disease; Dementia; Dihydroergotoxine; Humans; Nafronyl; Papaverine; Pentoxifylline; Piracetam; Procaine; Psychotropic Drugs

1985
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
    Vestnik khirurgii imeni I. I. Grekova, 1982, Volume: 129, Issue:11

    Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Male; Middle Aged; Nicotinic Acids; Papaverine; Penicillins; Pentoxifylline; Povidone; Procaine; Promedol

1982
[Some mechanisms of papaverine and trental action in patients with acute arterial obstruction].
    Vestnik khirurgii imeni I. I. Grekova, 1980, Volume: 124, Issue:5

    Topics: Acute Disease; Adrenocorticotropic Hormone; Aged; Arm; Cyclic AMP; Embolism; Hemodynamics; Humans; Hydrocortisone; Middle Aged; Papaverine; Pentoxifylline; Theobromine

1980
Effect of phosphodiesterase inhibitors on heart contractile behaviour, protein kinase activity and cyclic nucleotide levels.
    Journal of molecular and cellular cardiology, 1980, Volume: 12, Issue:10

    Topics: Animals; Cyclic AMP; Cyclic GMP; Myocardial Contraction; Myocardium; Nucleotides, Cyclic; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Theophylline

1980
Protein secretion induced by isoproterenol or pentoxifylline in lacrimal gland: Ca2+ effects.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 1

    Topics: Animals; Bucladesine; Calcium; Carbachol; Cyclic AMP; Isoproterenol; Kinetics; Lacrimal Apparatus; Male; Papaverine; Pentoxifylline; Proteins; Rats; Rats, Inbred Strains; Theobromine

1984
[Use of transcatheter intra-arterial infusion of drug mixtures in the combined treatment of patients with obliterating vascular diseases in the terminal stage of limb ischemia].
    Klinicheskaia khirurgiia, 1994, Issue:7

    Topics: Adult; Aged; Amputation, Surgical; Anti-Bacterial Agents; Arterial Occlusive Diseases; Ascorbic Acid; Combined Modality Therapy; Dextrans; Drug Combinations; Heparin; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Middle Aged; Nicergoline; Papaverine; Pentoxifylline; Procaine; Vasodilator Agents; Vitamin B Complex

1994
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines

1999
[Prolonged intra-arterial therapy in surgical treatment of patients with critical lower limb ischemia].
    Khirurgiia, 2001, Issue:12

    Topics: Actihaemyl; Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anticoagulants; Critical Care; Dipyridamole; Female; Fibrinolytic Agents; Heparin; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Male; Microsurgery; Middle Aged; Omentum; Papaverine; Pentoxifylline; Platelet Aggregation Inhibitors; Risk Factors; Sympathectomy; Treatment Outcome; Vasodilator Agents

2001
Retrospective analysis of our cases with sudden hearing loss.
    The Journal of otolaryngology, 2003, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anticoagulants; Audiometry, Pure-Tone; Auditory Threshold; Child; Dextrans; Diazepam; Drug Therapy, Combination; Female; Glucocorticoids; Hearing Loss, Sudden; Humans; Male; Methylprednisolone; Middle Aged; Papaverine; Pentoxifylline; Prognosis; Retrospective Studies; Risk Factors; Treatment Outcome; Vasodilator Agents

2003
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
    Clinical hemorheology and microcirculation, 2007, Volume: 36, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2007
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
    Clinical hemorheology and microcirculation, 2008, Volume: 40, Issue:2

    Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2008
Trace element levels in ischemia-reperfusion injury after left colonic anastomosis in rats and effects of papaverine and pentoxiphylline on vascular endothelial growth factor in anastomosis healing.
    Acta gastro-enterologica Belgica, 2011, Volume: 74, Issue:1

    Topics: Animals; Colon; Female; Papaverine; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Trace Elements; Vascular Endothelial Growth Factor A; Vasodilator Agents; Wound Healing

2011
Current approach to the man with acute phase Peyronie's disease--case presentation and discussion.
    The journal of sexual medicine, 2011, Volume: 8, Issue:6

    Topics: Adult; Arginine; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Injections, Intralesional; Interferons; Male; Papaverine; Penile Induration; Pentoxifylline; Phosphodiesterase Inhibitors; Prognosis; Randomized Controlled Trials as Topic; Traction; Treatment Outcome; Ultrasonography, Doppler, Duplex; Vasodilator Agents; Verapamil

2011
Papaverine as a replacement for pentoxifylline to select thawed testicular or epididymal spermatozoa before ICSI.
    Gynecologie, obstetrique & fertilite, 2015, Volume: 43, Issue:12

    Topics: Animals; Cell Survival; Cryopreservation; Epididymis; Fertilization in Vitro; Hot Temperature; Humans; Infertility, Male; Male; Mice; Papaverine; Pentoxifylline; Semen Preservation; Sperm Injections, Intracytoplasmic; Sperm Motility; Testis

2015