papaverine and omeprazole

papaverine has been researched along with omeprazole in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Ohno, T; Okabe, S1
Hirose, N; Ishihara, T; Ohno, T; Okabe, S; Uramoto, H1
Lou, YQ; Zhao, L2
Kelicen, P; Pekiner, C; Sarioğlu, Y; Uma, S1

Reviews

1 review(s) available for papaverine and omeprazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for papaverine and omeprazole

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Gastric surface epithelial cell damage induced by restraint and water-immersion stress in rats. Protective effects of 16,16-dimethyl-prostaglandin E2.
    Journal of clinical gastroenterology, 1988, Volume: 10 Suppl 1

    Topics: 16,16-Dimethylprostaglandin E2; 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Atropine; Benzimidazoles; Gastric Acid; Gastric Mucosa; Gastrointestinal Motility; Immersion; Male; Microscopy, Electron, Scanning; Omeprazole; Papaverine; Peptic Ulcer; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological

1988
Surface epithelial cell damage induced by restraint and water-immersion stress in rats effects of 16,16-dimethyl prostaglandin E2 on stress-induced gastric lesions.
    Japanese journal of pharmacology, 1987, Volume: 45, Issue:3

    Topics: 16,16-Dimethylprostaglandin E2; 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Atropine; Benzimidazoles; Epithelial Cells; Epithelium; Gastric Mucosa; Gastrointestinal Motility; Immersion; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Omeprazole; Papaverine; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological

1987
[In vitro studies on omeprazole metabolism in rat liver microsomes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Hydroxylation; In Vitro Techniques; Male; Mephenytoin; Microsomes, Liver; Omeprazole; Papaverine; Rats; Rats, Sprague-Dawley

1995
[Enzyme kinetic studies on the in vitro metabolism of omeprazole by Chinese human liver microsomes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:5

    Topics: Adult; Anti-Ulcer Agents; Humans; Hydroxylation; In Vitro Techniques; Mephenytoin; Microsomes, Liver; Omeprazole; Papaverine

1996
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
    Pharmacological research, 2002, Volume: 46, Issue:4

    Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Omeprazole; Papaverine; Phenylephrine; Potassium Channel Blockers; Proton Pump Inhibitors; Rats; Tetraethylammonium; Vasoconstrictor Agents; Vasodilator Agents

2002