papaverine has been researched along with drotaverin in 112 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (32.14) | 18.7374 |
1990's | 11 (9.82) | 18.2507 |
2000's | 28 (25.00) | 29.6817 |
2010's | 32 (28.57) | 24.3611 |
2020's | 5 (4.46) | 2.80 |
Authors | Studies |
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Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Domokos, D; Falkay, G; Fülöp, F; Gáspár, R | 1 |
Balant, L; Buri, P; Rutz-Coudray, MH | 1 |
Simon, G; Szüts, T; Vargay, Z; Winter, M | 2 |
Buri, P; Giust, J; Rutz-Coudray, MH | 1 |
Matejka, Z; Minker, E | 1 |
Marton, S; Szentmiklósi, P | 2 |
Dávid, A; Gyarmati, L; Mészáros, Z; Rácz, I; Szentmiklósi, P | 1 |
Blaskó, G; Hermecz, I; Kapui, Z; Sarkadi, B; Szentmiklósi, P; Tardos, L | 1 |
Dotsenko, NIa | 1 |
Mikhaĭlova, VA; Simochkina, ZA; Velikaia, LA | 1 |
Kovács, B; Pécsiné Szebellédi, I; Regdon, G | 2 |
Andreĭchin, MA; Gnatovich, IG; Il'ina, NI; Kiĭko, LG | 1 |
Bagdasarian, EG; Egishian, RE; Krylov, AA | 1 |
Maitai, CK; Munenge, RW; Njoroge, DK | 1 |
Gregus, Z; Losonczy, H; Nagy, I | 1 |
Chekman, IS; Kazak, LI | 1 |
Burleva, EP; Ermolaev, VL | 1 |
Blazsó, G; Gerö, L; Minker, E; Végh, A | 1 |
Baranov, AG; Urakov, AL | 1 |
Küttel, S; Marton, S; Mezei, J; Rácz, I; Szentmiklósi, P | 1 |
Vecsey, D | 1 |
Gavrisiuk, VK; Shevchenko, RN | 1 |
Kálózdi, T; Maros, M; Molnár, L; Tantó, Z; Várhelyi, M | 1 |
Butvin, GK; Kavkalo, NN; Moldovan, VI; Pecheniuk, VN; Zaĭdman, VE | 1 |
Barta, O; Temesi, M; Varró, J | 1 |
Gurin, NG | 1 |
Leont'eva, GV; Nosova, VP | 1 |
Belley, E | 1 |
Matveev, AD; Popov, AG; Sabaev, VV; Usachev, VV | 1 |
Leshchinskiĭ, LA; Pimenov, LT; Trusov, VV | 1 |
Kökény, G; Sebestyén, G; Szentmiklósi, P; Zájer, J | 1 |
Ermolaev, VL; Makarova, NP; Zavalskiĭ, II | 1 |
Bolaji, OO; Ogunbona, FA; Ogungbamila, FO; Ogunlana, EO; Onyeji, CO | 1 |
Bozhenko, VK; Ivanov, LS; Khmelevskiĭ, EV; Shishkin, AM; Zakharov, AG | 1 |
Kovaleva, OV; Porada, LV; Selivonenko, VG | 1 |
Sylvia, M | 1 |
Ashmarin, IP; Kiselev, OI; Zhilinskaia, IN | 1 |
Böcskei, Z; Friesz, A; Hermécz, I; Menyhárd, D; Simon, K; Tuza, T | 1 |
Shafik, A | 1 |
Arányi, P; Baranyi, A; Bence, J; Boronkay, E; Kapui, Z; Mikus, E; Urbán Szabó, K | 1 |
Kulikov, SV; Kuznechikhin, EP; Poliaev, IuP | 1 |
Kumar, A; Murthy, NS; Pundir, P; Sharma, JB | 1 |
Arányi, P; Finance, O; Tömösközi, Z | 1 |
Singer, J; Tar, A | 1 |
Garmish, OS; Kobeliatskiĭ, IuIu; Smirnova, EV; Zabashnyĭ, SI | 1 |
Blaskó, G; Jelakovic, B; Köszegi, G; Molnár, DL; Mrklic, B; Romics, I; Timberg, G | 1 |
PETRANYI, G; SZEGEDI, G | 1 |
MAKLARI, L | 1 |
PETRANYI, G; SZEGEDI, GD | 1 |
ZOLOTAREVSKY, VY | 1 |
Goel, N; Jain, P; Saxena, A; Singh, KC | 1 |
Melenevskiĭ, DA; Ukhal', MI | 1 |
Balcerkiewicz, M; Drobnik, L; Dubai, V; Dyderski, S; Grześkowiak, E; Szałek, E | 1 |
Balakina, IV; Bartosh, LF; Gridneva, LM | 1 |
Kharitonov, SV | 1 |
El-Khateeb, SZ; El-Saharty, YS; Metwaly, FH; Refaat, M | 1 |
Abdellatif, HE; Ayad, MM; Soliman, SM; Youssef, NF | 1 |
Abdellatef, HE; Ayad, MM; Soliman, SM; Youssef, NF | 1 |
Babaev, FF; Israfilbeĭli, SG | 1 |
Amin, AS; El-Sheikh, R; Gouda, AA; Zahran, F | 1 |
Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG | 1 |
Metwally, FH | 1 |
Girsa, VN; Nemtsov, LM; Nikolaeva, AG | 1 |
Gupta, B; Mittal, S; Nellore, V | 1 |
Guha, S; Mukhopadhyay, S; Patra, KK; Roy, A | 1 |
Debska, M; Debski, R; Mazurek, M; Niemiec, T | 1 |
Makarchuk, PA | 1 |
Horvath, B; Kesmarky, G; Toth, K; Vekasi, J | 1 |
Issa, YM; Zayed, SI | 1 |
Dzhanayev, YA; Golovenko, OV; Khalif, IL; Makarchuk, PA; Podmarenkova, LF; Quigley, EM | 1 |
Aruna, J; Kumar, P; Kumar, S; Malhotra, N; Roy, KK; Sharma, JB | 1 |
Bhave, S; Madhu, C; Mahavarkar, S | 1 |
Agrawal, SN; Chandurkar, NB; Pareek, A; Patil, RT; Tambe, SG; Uday, RB | 1 |
Jain, R; Rather, JA | 1 |
Akantappa Bandakkanavar, TK; Arora, P; Dash, A; Maiti, R | 1 |
Pshenkina, NN | 1 |
Bari, SB; Bhagwat, AM; Bhoir, SI; Dahivelkar, PP; Surana, SJ | 1 |
Demushkin, VP; Khaspekov, LG; Zhavoronkova, EV | 1 |
Ivshina, IB; Karpenko, JN; Mukhutdinova, AN; Richkova, MI; Vikhareva, EV | 1 |
Ilič, I; Kása, P; Papós, K; Pintye-Hódi, K; Sovány, T; Srčič, S | 1 |
Chikunova, BZ; Fadeeva, NA; Gubina, AV; Khomeriki, SG; Parfenov, AI; Poleva, NI; Ruchkina, IN; Shcherbakov, PL | 1 |
Efremov, LI; Firsova, LD; Ianova, OB; Kostiuchenko, LN; Pichugina, IM; Vasnev, OS | 1 |
Adel, S; ElKasabgy, NA | 1 |
Abdellatif, MA; Alzeeniny, HA; Ellaithy, MI; Ibrahim, MI; Salama, AH | 1 |
El Sibai, O; Shafik, AA; Shafik, IA | 1 |
Borka-Balás, R; Donáth-Nagy, G; Gáll, Z; Vancea, S | 1 |
El'-Registan, GI; Ivshina, IB; Mukhutdinova, AN; Mulyukin, AL; Suzina, NE; Tyumina, HA; Vikhareva, HV | 1 |
Babinets', AI; Babinets', LS; Droniak, IuV; Pliashko, KO | 1 |
Bałkota, M; Tomaszewski, D | 1 |
Sathiyasekaran, M | 1 |
Aggarwal, V | 1 |
Akhtar, H; Narang, M; Shah, D | 1 |
Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S | 1 |
Lajtai, A; Lakatos, Á; Mayer, M; Miseta, A; Porpáczy, Z | 1 |
Guttman, A; Mikus, EG; Patai, Z | 2 |
Al-Harrasi, A; Csuk, R; Heller, L; Loesche, A; Pavel, IZ; Sommerwerk, S | 1 |
Qi, XX; Wan, XY; Xue, XC | 1 |
Liu, J; Wang, JK | 1 |
Ahmad, B; Anwar, F; Ismail, T; Nazir, S; Raza, Z; Rehman, AU; Saleem, U; Sanawar, M | 1 |
Rzymski, P; Tomczyk, KM; Wilczak, M | 1 |
Badawy, AA; Elmalak, NSA; Farag, MM; Louis, MM; Nessem, DI | 1 |
Dimejesi, IB; Ekwunife, IC; Ikeotuonye, AC; Nwafor, JI; Ojumah, BO; Umeora, OJ | 1 |
A Abdel Salam, R; Abdelshakour, MA; Attala, K; E Mostafa, A; Eissa, MS; Elsonbaty, A; M Hadad, G | 1 |
2 review(s) available for papaverine and drotaverin
Article | Year |
---|---|
[Mechanisms of the therapeutic action of vasodilator agents in cardiac insufficiency (review of the literature)].
Topics: Adrenergic alpha-Antagonists; Animals; Coronary Disease; Dogs; Heart Failure; Humans; Muscle Relaxants, Central; Nitroglycerin; Papaverine; Parasympatholytics; Phentolamine; Rabbits; Rats; Vasodilator Agents | 1981 |
[Safety profile of NO-SPA].
Topics: Analgesics; Humans; Papaverine; Parasympatholytics; Vasodilator Agents | 2002 |
24 trial(s) available for papaverine and drotaverin
Article | Year |
---|---|
Intra-arterial use of No-Spa+lidocaine in coxarthrosis.
Topics: Clinical Trials as Topic; Hip Joint; Humans; Injections, Intra-Arterial; Lidocaine; Osteoarthritis; Papaverine; Parasympatholytics | 1982 |
[Rheohepatographic changes under the effect of clinical trials of drugs in chronic nonspecific lung diseases].
Topics: Aminophylline; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; Ephedrine; Humans; Isoproterenol; Liver Circulation; Papaverine; Plethysmography, Impedance; Pneumonia; Strophanthins | 1980 |
Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor.
Topics: Cervix Uteri; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics; Pregnancy; Quaternary Ammonium Compounds; Sympatholytics; Time Factors | 2001 |
[Preparation no-shpa forte for the treatment of renal colic].
Topics: Adult; Aged; Colic; Female; Hemodynamics; Humans; Kidney Diseases; Male; Middle Aged; Papaverine; Parasympatholytics; Treatment Outcome | 2003 |
The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones.
Topics: Acute Disease; Adult; Colic; Double-Blind Method; Female; Humans; Kidney Calculi; Male; Pain Measurement; Papaverine; Parasympatholytics; Treatment Outcome; Ureteral Calculi | 2003 |
Drotaverine hydrochloride for augmentation of labor.
Topics: Adult; Analgesia, Obstetrical; Analgesics; Cervix Uteri; Double-Blind Method; Female; Humans; Labor Stage, First; Labor, Obstetric; Pain Measurement; Papaverine; Parasympatholytics; Postpartum Hemorrhage; Pregnancy | 2004 |
[Using prostaglandin inhibitor dicloberl in patients with ureteral calculi].
Topics: Adult; Aged; Analgesics, Opioid; Diclofenac; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain; Papaverine; Parasympatholytics; Prostaglandin Antagonists; Tramadol; Treatment Outcome; Ureteral Calculi | 2004 |
Bioavailability study of drotaverine from capsule and tablet preparations in healthy volunteers.
Topics: Adult; Area Under Curve; Biological Availability; Calibration; Capsules; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Male; Papaverine; Parasympatholytics; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets | 2004 |
[Functional state of kidneys and upper urogenital tract in patients with intraligamentary ovarian cysts in pre and postoperative periods during the treatment with spasmolytics].
Topics: Adult; Female; Female Urogenital Diseases; Humans; Ovarian Cysts; Papaverine; Parasympatholytics; Postoperative Care; Preoperative Care; Renal Artery; Ultrasonography; Urodynamics | 2006 |
[Vegetotropic therapy and hypobaric hypoxic adaptation in gallbladder motor dysmotility].
Topics: Adaptation, Physiological; Adolescent; Adrenergic beta-Antagonists; Adult; Autonomic Nervous System; Biliary Dyskinesia; Cholecystography; Dopamine Antagonists; Female; Gallbladder; Gallbladder Emptying; Humans; Hypoxia; Male; Metoclopramide; Middle Aged; Papaverine; Parasympatholytics; Propranolol; Treatment Outcome; Ultrasonography | 2007 |
Drotaverine hydrochloride versus hyoscine-N-butylbromide in augmentation of labor.
Topics: Adult; Butylscopolammonium Bromide; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics; Pregnancy; Prospective Studies | 2008 |
Study of drotaverine on first stage of labour and pregnancy outcome.
Topics: Drug-Related Side Effects and Adverse Reactions; Female; Humans; Labor Onset; Labor Stage, First; Labor, Obstetric; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Pregnancy; Pregnancy Outcome; Prospective Studies | 2007 |
[Comparative efficacy and tolerability of drotaverine 80 mg and ibuprofen 400 mg in patients with primary dysmenorrhoea--protocol DOROTA].
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dysmenorrhea; Female; Humans; Ibuprofen; Pain Measurement; Papaverine; Patient Satisfaction; Poland; Treatment Outcome; Women's Health | 2007 |
[Dynamics of indices of visceral sensitivity in patients with irritable bowel syndrome treated with spasmolytics].
Topics: Abdominal Pain; Adult; Butylscopolammonium Bromide; Female; Humans; Hyperalgesia; Irritable Bowel Syndrome; Male; Pain Measurement; Pain Threshold; Papaverine; Parasympatholytics; Surveys and Questionnaires; Treatment Outcome; Viscera | 2007 |
Interactions between symptoms and motor and visceral sensory responses of irritable bowel syndrome patients to spasmolytics (antispasmodics).
Topics: Administration, Oral; Administration, Rectal; Adult; Butylscopolammonium Bromide; Calcium Gluconate; Calendula; Colon, Sigmoid; Diarrhea; Female; Gastrointestinal Motility; Humans; Irritable Bowel Syndrome; Male; Motor Neurons; Pain; Pain Measurement; Papaverine; Parasympatholytics; Plant Preparations; Rectum; Sensory Receptor Cells; Severity of Illness Index; Suppositories; Tablets; Treatment Outcome; Young Adult | 2009 |
Comparison of efficacy of oral drotaverine plus mefenamic acid with paracervical block and with intravenous sedation for pain relief during hysteroscopy and endometrial biopsy.
Topics: Adjuvants, Anesthesia; Adult; Analgesics; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anesthetics, Intravenous; Diazepam; Drug Therapy, Combination; Endometrium; Female; Humans; Hypnotics and Sedatives; Hysteroscopy; Mefenamic Acid; Middle Aged; Pain Measurement; Papaverine; Pentazocine; Treatment Outcome; Young Adult | 2009 |
A randomised controlled study comparing Drotaverine hydrochloride and Valethamate bromide in the augmentation of labour.
Topics: Adult; Cervical Ripening; Cervix Uteri; Female; Humans; Injections, Intramuscular; Labor Stage, First; Papaverine; Parasympatholytics; Pregnancy; Pregnancy Outcome; Prospective Studies; Quaternary Ammonium Compounds; Time Factors; Young Adult | 2010 |
Efficacy and safety of aceclofenac and drotaverine fixed-dose combination in the treatment of primary dysmenorrhoea: a double-blind, double-dummy, randomized comparative study with aceclofenac.
Topics: Adolescent; Adult; Analgesics; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Combinations; Dysmenorrhea; Female; Humans; Papaverine; Phosphodiesterase Inhibitors; Treatment Outcome; Young Adult | 2010 |
Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety.
Topics: Adult; Analgesics; Diclofenac; Female; Humans; Injections, Intramuscular; Male; Pain Measurement; Papaverine; Renal Colic; Single-Blind Method | 2012 |
[The role of small bowel microflora in the development of secondary lactase deficiency and the possibilities of its treatment with probiotics].
Topics: Adult; Analgesics; Bifidobacterium; Blind Loop Syndrome; Enterococcus faecium; Female; Humans; Intestine, Small; Irritable Bowel Syndrome; Lactase; Lactose Intolerance; Male; Papaverine; Probiotics; Treatment Outcome | 2013 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; Papaverine; Parasympatholytics; Parity; Pregnancy; Time Factors; Young Adult | 2014 |
Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study.
Topics: Adolescent; Adult; Analgesics; Anesthesia, Epidural; Female; Humans; Injections, Intramuscular; Male; Papaverine; Parasympatholytics; Postoperative Complications; Premedication; Single-Blind Method; Treatment Outcome; Urinary Retention; Urination; Young Adult | 2015 |
Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial.
Topics: Abdominal Pain; Absenteeism; Administration, Oral; Child; Child, Preschool; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; India; Male; Papaverine; Treatment Outcome | 2015 |
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Labor Pain; Labor, Obstetric; Oxytocin; Papaverine; Pregnancy | 2022 |
86 other study(ies) available for papaverine and drotaverin
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity.
Topics: Animals; Dose-Response Relationship, Drug; Female; Isoquinolines; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; rho-Associated Kinases; Structure-Activity Relationship; Uterine Contraction | 2018 |
[The usefulness of compartmental analysis for the development of sustained release drug forms; experiences with drotaverine in humans].
Topics: Delayed-Action Preparations; Humans; Models, Biological; Papaverine | 1979 |
The intestinal absorption and excretion of 14C drotaverin in rats.
Topics: Animals; Bile; Carbon Radioisotopes; Common Bile Duct; Intestinal Absorption; Intestine, Small; Ligation; Male; Papaverine; Rats; Time Factors | 1979 |
[Prolonged liberation, by inclusion in an inert matrix, of drotaverine coprecipitate].
Topics: Delayed-Action Preparations; Papaverine; Parasympatholytics | 1979 |
Effect of mepacrine on gastric motility in the rat.
Topics: Administration, Oral; Animals; Bencyclane; Chloroquine; Female; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Injections, Intraperitoneal; Papaverine; Quinacrine; Rats | 1979 |
[Practical significance of drug equivalence in preclinical research, with special reference to drotaverin and its salt with theophylline-7-acetic acid].
Topics: Animals; Biological Availability; Drug Evaluation, Preclinical; Mice; Papaverine; Theophylline | 1979 |
Data on the metabolism of benzylisoquinoline derivatives. The metabolism of drotaverin.
Topics: Animals; Benzyl Compounds; Feces; Isoquinolines; Mass Spectrometry; Papaverine; Rats; Spectrophotometry, Ultraviolet | 1975 |
Comparative studies of drotaverine--acephyllinate (Depogen) and pentoxifylline (Trental).
Topics: Animals; Cell Aggregation; Drug Combinations; Drug Evaluation, Preclinical; Erythrocytes; Humans; Leukocytes; Papaverine; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 3; Rabbits; Theophylline | 1992 |
[The effect of food intake, atropine and No-spa on autonomic tonus and hemodynamic indices in patients with peptic ulcer].
Topics: Adult; Atropine; Autonomic Nervous System; Duodenal Ulcer; Feeding Behavior; Female; Hemodynamics; Humans; Male; Middle Aged; Papaverine; Parasympatholytics | 1989 |
[A case of Lyell's syndrome].
Topics: Aged; Drug Combinations; Drug Therapy, Combination; Female; Humans; Papaverine; Parasympatholytics; Penicillins; Plant Extracts; Stevens-Johnson Syndrome | 1989 |
[Preparation and in vitro study of suppositories containing No-Spa. I. Significance of choosing the basic substance. Determination of physical parameters of suppositories].
Topics: Papaverine; Parasympatholytics; Vasodilator Agents | 1989 |
[Preparation and in vitro study of suppositories containing No-Spa. II. Determination of release of the active principle by membrane diffusion methods].
Topics: Diffusion; Drug Stability; Membranes, Artificial; Papaverine; Parasympatholytics; Suppositories; Vasodilator Agents | 1989 |
[Use of no-shpa and phenicaberan in hypertonic biliary dyskinesia in patients with viral hepatitis].
Topics: Adolescent; Adult; Benzofurans; Biliary Dyskinesia; Drug Evaluation; Hepatitis A; Hepatitis B; Humans; Middle Aged; Papaverine; Parasympatholytics | 1988 |
[Hemodynamic indicators in patients with duodenal ulcer after pharmacological tests].
Topics: Aluminum Hydroxide; Benzocaine; Drug Combinations; Duodenal Ulcer; Hemodynamics; Humans; Magnesium Hydroxide; Papaverine; Sorbitol | 1987 |
A comparative study of two antispasmodic products: Buscopan and NO-Spa.
Topics: Animals; Butylscopolammonium Bromide; Disease Models, Animal; Guinea Pigs; Ileal Diseases; Papaverine; Parasympatholytics; Scopolamine Derivatives; Spasm | 1985 |
Effect of prostaglandins and drotaverine on ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Blood Platelets; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Humans; Papaverine; Parasympatholytics; Platelet Aggregation; Prostaglandins E | 1974 |
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Male; Middle Aged; Nicotinic Acids; Papaverine; Penicillins; Pentoxifylline; Povidone; Procaine; Promedol | 1982 |
Neurogenic component in the effect of papaverine, drotaverine and bencyclane.
Topics: Animals; Bencyclane; Calcium; Cycloheptanes; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Nalorphine; Naloxone; Papaverine; Parasympatholytics; Rana esculenta; Receptors, Opioid; Synapses; Synaptic Transmission | 1983 |
[Biochemical basis for the spasmolytic effect of isoquinoline and phenothiazine derivatives].
Topics: Animals; In Vitro Techniques; Mitochondria, Muscle; Moricizine; Muscle, Smooth; Muscle, Smooth, Vascular; Nonachlazine; Oxygen Consumption; Papaverine; Parasympatholytics; Phenothiazines; Phosphorylation; Rats; Swine | 1983 |
A new method for high-performance liquid chromatographic determination of drotaverine in plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Papaverine; Parasympatholytics; Rats; Spectrophotometry, Ultraviolet | 1984 |
Importance of No-Spa and Probon combination in the conservative treatment of ureterolithiasis patients.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Papaverine; Parasympatholytics; Pyrimidinones; Ureteral Calculi | 1984 |
[The role of pharmacological tests in the early diagnosis of pulmonary hypertension].
Topics: Aminophylline; Humans; Hypertension, Pulmonary; Papaverine; Time Factors | 1983 |
Biopharmaceutical aspects of Depogen.
Topics: Animals; Biopharmaceutics; Diffusion; Dogs; Drug Combinations; Female; Male; Mice; Models, Biological; Papaverine; Rats; Theophylline | 1983 |
[Clinical x-ray diagnosis of an elongated large intestine].
Topics: Adult; Aged; Atropine; Chronic Disease; Diagnosis, Differential; Female; Gastrointestinal Neoplasms; Humans; Intestine, Large; Male; Middle Aged; Neostigmine; Palpation; Papaverine; Radiography | 1983 |
Examination of the pain relieving-effect of intra-arterial No-Spa treatment of coxarthrosis.
Topics: Adult; Aged; Female; Hip Joint; Humans; Injections, Intra-Arterial; Male; Middle Aged; Osteoarthritis; Pain; Papaverine; Parasympatholytics | 1982 |
[Characteristic features of the functioning of arteriolovenular anastomoses in pharmacological arterial hyperemia].
Topics: Aminophylline; Animals; Arterioles; Arteriovenous Anastomosis; Collateral Circulation; Hyperemia; Male; Mesentery; Papaverine; Rats; Rats, Inbred Strains; Venules | 1982 |
Treatment of coxarthroses with intraarterial injection of No-Spa + Lidocaine.
Topics: Female; Hip Joint; Humans; Injections, Intra-Arterial; Joint Diseases; Lidocaine; Male; Middle Aged; Papaverine | 1980 |
[Use of No-Shpa in combination with vitamins in motion sickness].
Topics: Drug Evaluation; Drug Therapy, Combination; Humans; Motion Sickness; Papaverine; Placebos; Scopolamine; Vitamins | 1981 |
[Changes in renal hemodynamics and renal function in patients with cardiac insufficiency treated with vasodilators].
Topics: Bencyclane; Dipyridamole; Heart Failure; Humans; Kidney; Papaverine; Renal Circulation; Vasodilator Agents | 1981 |
Effects of drotaverin and depogen on gastric emptying in beagle dogs.
Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Drug Combinations; Female; Gastric Emptying; Male; Papaverine; Parasympatholytics; Theophylline | 1981 |
Qualitative and quantitative determination of drotaverine metabolites in rat bile.
Topics: Administration, Oral; Animals; Bile; Biotransformation; Chromatography, Thin Layer; Injections, Intravenous; Male; Papaverine; Parasympatholytics; Perfusion; Rats | 1980 |
[Use of transcatheter intra-arterial infusion of drug mixtures in the combined treatment of patients with obliterating vascular diseases in the terminal stage of limb ischemia].
Topics: Adult; Aged; Amputation, Surgical; Anti-Bacterial Agents; Arterial Occlusive Diseases; Ascorbic Acid; Combined Modality Therapy; Dextrans; Drug Combinations; Heparin; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Middle Aged; Nicergoline; Papaverine; Pentoxifylline; Procaine; Vasodilator Agents; Vitamin B Complex | 1994 |
High-performance liquid chromatographic method for the determination of drotaverine in human plasma and urine.
Topics: Chromatography, High Pressure Liquid; Humans; Male; Papaverine; Regression Analysis; Spectrophotometry, Ultraviolet; Sympatholytics | 1993 |
[Effect of the drug no-spa on the status of the arterioles in rat skeletal muscles after total gamma-irradiation with a dose of 1 Gy].
Topics: Animals; Arterioles; Gamma Rays; Male; Muscles; Papaverine; Rats; Rats, Wistar; Vasodilator Agents | 1994 |
[Changes in the thermogram of the precordial area and the hands under the influence of the No-Shpa test in stenocardia patients].
Topics: Angina Pectoris; Body Temperature Regulation; Color; Hand; Hemodynamics; Humans; Male; Middle Aged; Papaverine; Thermography; Thorax; Time Factors; Vasodilator Agents | 1998 |
[Interspecies allometric scaling in pharmacokinetics of drugs].
Topics: Animals; Body Weight; Cats; Dogs; Drug Combinations; Humans; Mice; Organ Size; Papaverine; Parasympatholytics; Rats; Regression Analysis; Species Specificity; Theophylline; Tissue Distribution | 1998 |
[Inhibiting effect of no-spa on paragrippe virus reproduction].
Topics: Animals; Anti-Infective Agents; Chick Embryo; Inhibitory Concentration 50; Papaverine; Paramyxoviridae; Virus Replication | 1999 |
[Pseudopolymorphism of NO-SPA, 1-(3,4-diethoxy-benzyl)-6,7-diethoxy-3,4-dihydro-isoquinoli ne hydrochloride].
Topics: Crystallography, X-Ray; Drug Stability; Models, Molecular; Molecular Conformation; Molecular Structure; Papaverine; Parasympatholytics | 1999 |
Origin of rectal electric waves: further study.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Defecation; Dogs; Electrophysiology; Enteric Nervous System; Female; Ganglionectomy; Gastrointestinal Motility; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; Papaverine; Parasympatholytics; Phentolamine; Pressure; Propranolol; Rectum | 1999 |
Behavioural effects of selective PDE4 inhibitors in relation to inhibition of catalytic activity and competition for [3H]rolipram binding.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Binding, Competitive; Catalytic Domain; Cyclic Nucleotide Phosphodiesterases, Type 4; Papaverine; Parasympatholytics; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Tritium | 1999 |
[Rare forms of partial gigantism due to vascular hypoplasia].
Topics: Arm; Arteriovenous Malformations; Child, Preschool; Female; Gigantism; Humans; Leg; Papaverine; Radiography; Vasodilator Agents | 1993 |
Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic Nucleotide Phosphodiesterases, Type 4; Diltiazem; Female; Half-Life; In Vitro Techniques; Kinetics; Membranes; Nitrendipine; Papaverine; Parasympatholytics; Phosphodiesterase Inhibitors; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Sprague-Dawley; Uterus | 2002 |
[COMPARATIVE CLINICAL MEASUREMENT OF THE EFFECT OF SPASMOLYTIES. (DATA ON THE CLINICAL PHARMACOLOGY OF NO-SPA)].
Topics: Cardiovascular Agents; Muscle Relaxants, Central; Papaverine; Pharmacology; Vasodilator Agents | 1963 |
EXPERIENCE OBTAINED WITH A NEW SPASMOLYTIC DRUG (NO-SPA).
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cholelithiasis; Colic; Colitis; Duodenal Ulcer; Dysmenorrhea; Female; Humans; Kidney Calculi; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Peptic Ulcer; Quinolines | 1963 |
COMPARATIVE CLINICAL STUDY OF THE POTENCY OF SPASMOLYTICS (OBSERVATIONS REGARDING THE CLINICAL PHARMACOLOGY OF NO-SPA).
Topics: Humans; Injections, Intra-Arterial; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Pharmacology, Clinical; Vascular Diseases; Vasomotor System | 1963 |
NO-SPA, A NEW SPASMOLYTIC FOR THE TREATMENT OF THROMBOEMBOLIC AFFECTIONS OF THE LOWER EXTREMITIES.
Topics: Lower Extremity; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Quinolines; Thromboembolism | 1965 |
[New approaches to diagnosing and treating hyperkinetic biliary dyskinesia associated with chronic acalculous cholecystitis].
Topics: Acalculous Cholecystitis; Adult; Biliary Dyskinesia; Calcium Channel Blockers; Chronic Disease; Female; Humans; Male; Middle Aged; Morpholines; Papaverine; Parasympatholytics; Quaternary Ammonium Compounds; Time Factors; Treatment Outcome; Ultrasonography | 2004 |
Transport properties and electroanalytical response characteristics of drotaverine ion-selective sensors.
Topics: Calibration; Electrochemistry; Ion-Selective Electrodes; Membranes, Artificial; Papaverine; Parasympatholytics; Permeability; Pharmaceutical Preparations; Polyvinyl Chloride; Potentiometry; Sensitivity and Specificity; Tablets; Time Factors | 2005 |
Application of new membrane selective electrodes for the determination of drotaverine hydrochloride in tablets and plasma.
Topics: Calibration; Electrodes; Humans; Papaverine; Parasympatholytics; Sensitivity and Specificity; Tablets | 2006 |
A comparative study on various spectrometries with thin layer chromatography for simultaneous analysis of drotaverine and nifuroxazide in capsules.
Topics: Anti-Infective Agents; Calibration; Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Drug Stability; Hydroxybenzoates; Methanol; Nitrofurans; Papaverine; Pharmaceutical Preparations; Reference Standards; Spectrophotometry; Spectrophotometry, Ultraviolet; Spectrum Analysis | 2006 |
Spectrophotometric and spectrodensitometric determination of paracetamol and drotaverine HCl in combination.
Topics: Acetaminophen; Chromatography, Thin Layer; Densitometry; Hydrochloric Acid; Papaverine; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2007 |
Spectrophotometric determination of pipazethate HCl, dextromethorphan HBr and drotaverine HCl in their pharmaceutical preparations.
Topics: Antitussive Agents; Benzothiadiazines; Calibration; Chloroform; Dextromethorphan; Dose-Response Relationship, Drug; Methylene Chloride; Molecular Structure; Naphthalenesulfonates; Papaverine; Pharmaceutical Preparations; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Time Factors; Water | 2007 |
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2007 |
Simultaneous determination of nifuroxazide and drotaverine hydrochloride in pharmaceutical preparations by bivariate and multivariate spectral analysis.
Topics: Hydroxybenzoates; Multivariate Analysis; Nitrofurans; Papaverine; Pharmaceutical Preparations; Spectrophotometry | 2008 |
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2008 |
Cathodic adsorptive stripping voltammetry of drotaverine hydrochloride and its determination in tablets and human urine by differential pulse voltammetry.
Topics: Adsorption; Calibration; Chemistry Techniques, Analytical; Humans; Hydrogen-Ion Concentration; Molecular Structure; Papaverine; Tablets | 2009 |
Voltammetric behaviour of drotaverine hydrochloride in surfactant media and its enhancement determination in Tween-20.
Topics: Adsorption; Carbon; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Models, Chemical; Papaverine; Polysorbates; Reproducibility of Results; Surface Properties; Surface-Active Agents; Tablets | 2011 |
[Influence of Perftoran nanoemulsion on blood plasma concentrations of lipophilic drugs].
Topics: Animals; Benzimidazoles; Blood Substitutes; Fluorocarbons; Hydrophobic and Hydrophilic Interactions; Ketorolac; Male; Papaverine; Protein Binding; Rabbits; Verapamil | 2012 |
Simultaneous determination of diclofenac potassium and drotaverine hydrochloride in human plasma using reversed-phase high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diclofenac; Humans; Least-Squares Analysis; Liquid-Liquid Extraction; Papaverine; Reproducibility of Results; Sensitivity and Specificity | 2012 |
Effects of drotaverine hydrochloride on viability of rat cultured cerebellar granulocytes.
Topics: Animals; Animals, Newborn; Cell Survival; Cerebellum; Dose-Response Relationship, Drug; Granulocytes; Molecular Structure; Papaverine; Parasympatholytics; Primary Cell Culture; Rats | 2012 |
Biodegradation of drotaverine hydrochloride by free and immobilized cells of Rhodococcus rhodochrous IEGM 608.
Topics: Biodegradation, Environmental; Biotransformation; Cells, Immobilized; Culture Media; Gas Chromatography-Mass Spectrometry; Papaverine; Rhodococcus | 2012 |
Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics.
Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Computer Simulation; Lactose; Mannitol; Models, Chemical; Neural Networks, Computer; Papaverine; Pharmaceutical Preparations; Powders; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
[Nutricional support in the complex treatment of a patient with esophageal spasm].
Topics: Antidepressive Agents; Benzodiazepines; Combined Modality Therapy; Drug Therapy, Combination; Enteral Nutrition; Esophageal Spasm, Diffuse; Female; Humans; Middle Aged; Papaverine; Parasympatholytics; Treatment Outcome | 2013 |
Design of innovated lipid-based floating beads loaded with an antispasmodic drug: in-vitro and in-vivo evaluation.
Topics: Adult; Alginates; Animals; Diarrhea; Dogs; Drug Delivery Systems; Emulsions; Glucuronic Acid; Hexuronic Acids; Humans; Liposomes; Methylcellulose; Myristates; Papaverine; Parasympatholytics; Pharmaceutical Preparations; Triglycerides | 2014 |
On the etiology of the electric activity of the external anal and urethral sphincters.
Topics: Adolescent; Adult; Anal Canal; Animals; Child; Dogs; Electromyography; Female; Humans; Infant, Newborn; Male; Middle Aged; Muscle Fibers, Skeletal; Myocytes, Smooth Muscle; Nerve Block; Papaverine; Parasympatholytics; Urethra; Young Adult | 2014 |
Rapid LC-MS/MS method for determination of drotaverine in a bioequivalence study.
Topics: Chromatography, Liquid; Humans; Imipramine; Methanol; Papaverine; Plasma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Therapeutic Equivalency | 2014 |
Drotaverine hydrochloride degradation using cyst-like dormant cells of Rhodococcus ruber.
Topics: Biodegradation, Environmental; Culture Media; Environmental Pollutants; Papaverine; Rhodococcus; Temperature | 2015 |
[Efficiency of etiologic correction of concomitant ascaridosis in the complex treatment of chronic pancreatitis].
Topics: Abdominal Pain; Albendazole; Analgesics; Animals; Anthelmintics; Ascariasis; Ascaris; Drug Therapy, Combination; Dysbiosis; Dyspepsia; Feces; Female; Gastrointestinal Agents; Humans; Male; Pancreas; Pancreatitis, Chronic; Pancrelipase; Papaverine; Treatment Outcome | 2014 |
Management of Recurrent Abdominal Pain: Have we Reached the end of the Tunnel?
Topics: Abdominal Pain; Chronic Pain; Female; Gastrointestinal Diseases; Humans; Male; Papaverine | 2015 |
Drotaverine for Recurrent Abdominal Pain in Children.
Topics: Abdominal Pain; Chronic Pain; Female; Gastrointestinal Diseases; Humans; Male; Papaverine | 2015 |
Evaluation of the efficiency of continuous wavelet transform as processing and preprocessing algorithm for resolution of overlapped signals in univariate and multivariate regression analyses; an application to ternary and quaternary mixtures.
Topics: Acetaminophen; Algorithms; Aminophenols; Analgesics; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Multivariate Analysis; Papaverine; Spectrophotometry; Wavelet Analysis | 2016 |
Embutramide, a Component of Tanax(®) (T-61) as a New Drug of Abuse?
Topics: Adolescent; Adult; Alprazolam; Amides; Drug Combinations; Humans; Male; Papaverine; Quaternary Ammonium Compounds; Substance-Related Disorders; Tetracaine | 2016 |
Potential L-Type Voltage-Operated Calcium Channel Blocking Effect of Drotaverine on Functional Models.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Electrophysiological Phenomena; Guinea Pigs; Male; Muscle Contraction; Papaverine; Potassium Chloride; Trachea | 2016 |
Drotaverine - a Concealed Cytostatic!
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mice; Papaverine; Tetrahydroisoquinolines | 2017 |
Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Trachea | 2018 |
Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome.
Topics: Administration, Oral; Adult; Aged; Chi-Square Distribution; China; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pain Measurement; Papaverine; Patient Safety; Risk Assessment; Severity of Illness Index; Single-Blind Method; Statistics, Nonparametric; Treatment Outcome; Young Adult | 2017 |
Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome: A retrospective study.
Topics: Adult; Combined Modality Therapy; Diarrhea; Electric Stimulation Therapy; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Papaverine; Parasympatholytics; Retrospective Studies; Treatment Outcome; Visual Analog Scale | 2018 |
Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cognitive Dysfunction; Female; Learning; Male; Memory; Mice; Molecular Docking Simulation; Morris Water Maze Test; Neurotransmitter Agents; Nootropic Agents; Open Field Test; Papaverine; Phosphodiesterase 4 Inhibitors; Protein Binding; Streptozocin | 2021 |
The Influence of Oral Drotaverine Administration on Materno-Fetal Circulation during the Second and Third Trimester of Pregnancy.
Topics: Administration, Oral; Female; Humans; Infant, Newborn; Papaverine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Premature Birth; Prospective Studies; Ultrasonography, Prenatal | 2022 |
Drotaverine Hydrochloride Superporous Hydrogel Hybrid System: a Gastroretentive Approach for Sustained Drug Delivery and Enhanced Viscoelasticity.
Topics: Biological Availability; Drug Delivery Systems; Hydrogels; Papaverine | 2022 |
Computer-Aided Design of Eco-Friendly Imprinted Polymer Decorated Sensors Augmented by Self-Validated Ensemble Modeling Designs for the Quantitation of Drotaverine Hydrochloride in Dosage Form and Human Plasma.
Topics: Computer-Aided Design; Humans; Papaverine; Polymers | 2023 |