papaverine and drotaverin

papaverine has been researched along with drotaverin in 112 studies

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199036 (32.14)18.7374
1990's11 (9.82)18.2507
2000's28 (25.00)29.6817
2010's32 (28.57)24.3611
2020's5 (4.46)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Domokos, D; Falkay, G; Fülöp, F; Gáspár, R1
Balant, L; Buri, P; Rutz-Coudray, MH1
Simon, G; Szüts, T; Vargay, Z; Winter, M2
Buri, P; Giust, J; Rutz-Coudray, MH1
Matejka, Z; Minker, E1
Marton, S; Szentmiklósi, P2
Dávid, A; Gyarmati, L; Mészáros, Z; Rácz, I; Szentmiklósi, P1
Blaskó, G; Hermecz, I; Kapui, Z; Sarkadi, B; Szentmiklósi, P; Tardos, L1
Dotsenko, NIa1
Mikhaĭlova, VA; Simochkina, ZA; Velikaia, LA1
Kovács, B; Pécsiné Szebellédi, I; Regdon, G2
Andreĭchin, MA; Gnatovich, IG; Il'ina, NI; Kiĭko, LG1
Bagdasarian, EG; Egishian, RE; Krylov, AA1
Maitai, CK; Munenge, RW; Njoroge, DK1
Gregus, Z; Losonczy, H; Nagy, I1
Chekman, IS; Kazak, LI1
Burleva, EP; Ermolaev, VL1
Blazsó, G; Gerö, L; Minker, E; Végh, A1
Baranov, AG; Urakov, AL1
Küttel, S; Marton, S; Mezei, J; Rácz, I; Szentmiklósi, P1
Vecsey, D1
Gavrisiuk, VK; Shevchenko, RN1
Kálózdi, T; Maros, M; Molnár, L; Tantó, Z; Várhelyi, M1
Butvin, GK; Kavkalo, NN; Moldovan, VI; Pecheniuk, VN; Zaĭdman, VE1
Barta, O; Temesi, M; Varró, J1
Gurin, NG1
Leont'eva, GV; Nosova, VP1
Belley, E1
Matveev, AD; Popov, AG; Sabaev, VV; Usachev, VV1
Leshchinskiĭ, LA; Pimenov, LT; Trusov, VV1
Kökény, G; Sebestyén, G; Szentmiklósi, P; Zájer, J1
Ermolaev, VL; Makarova, NP; Zavalskiĭ, II1
Bolaji, OO; Ogunbona, FA; Ogungbamila, FO; Ogunlana, EO; Onyeji, CO1
Bozhenko, VK; Ivanov, LS; Khmelevskiĭ, EV; Shishkin, AM; Zakharov, AG1
Kovaleva, OV; Porada, LV; Selivonenko, VG1
Sylvia, M1
Ashmarin, IP; Kiselev, OI; Zhilinskaia, IN1
Böcskei, Z; Friesz, A; Hermécz, I; Menyhárd, D; Simon, K; Tuza, T1
Shafik, A1
Arányi, P; Baranyi, A; Bence, J; Boronkay, E; Kapui, Z; Mikus, E; Urbán Szabó, K1
Kulikov, SV; Kuznechikhin, EP; Poliaev, IuP1
Kumar, A; Murthy, NS; Pundir, P; Sharma, JB1
Arányi, P; Finance, O; Tömösközi, Z1
Singer, J; Tar, A1
Garmish, OS; Kobeliatskiĭ, IuIu; Smirnova, EV; Zabashnyĭ, SI1
Blaskó, G; Jelakovic, B; Köszegi, G; Molnár, DL; Mrklic, B; Romics, I; Timberg, G1
PETRANYI, G; SZEGEDI, G1
MAKLARI, L1
PETRANYI, G; SZEGEDI, GD1
ZOLOTAREVSKY, VY1
Goel, N; Jain, P; Saxena, A; Singh, KC1
Melenevskiĭ, DA; Ukhal', MI1
Balcerkiewicz, M; Drobnik, L; Dubai, V; Dyderski, S; Grześkowiak, E; Szałek, E1
Balakina, IV; Bartosh, LF; Gridneva, LM1
Kharitonov, SV1
El-Khateeb, SZ; El-Saharty, YS; Metwaly, FH; Refaat, M1
Abdellatif, HE; Ayad, MM; Soliman, SM; Youssef, NF1
Abdellatef, HE; Ayad, MM; Soliman, SM; Youssef, NF1
Babaev, FF; Israfilbeĭli, SG1
Amin, AS; El-Sheikh, R; Gouda, AA; Zahran, F1
Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG1
Metwally, FH1
Girsa, VN; Nemtsov, LM; Nikolaeva, AG1
Gupta, B; Mittal, S; Nellore, V1
Guha, S; Mukhopadhyay, S; Patra, KK; Roy, A1
Debska, M; Debski, R; Mazurek, M; Niemiec, T1
Makarchuk, PA1
Horvath, B; Kesmarky, G; Toth, K; Vekasi, J1
Issa, YM; Zayed, SI1
Dzhanayev, YA; Golovenko, OV; Khalif, IL; Makarchuk, PA; Podmarenkova, LF; Quigley, EM1
Aruna, J; Kumar, P; Kumar, S; Malhotra, N; Roy, KK; Sharma, JB1
Bhave, S; Madhu, C; Mahavarkar, S1
Agrawal, SN; Chandurkar, NB; Pareek, A; Patil, RT; Tambe, SG; Uday, RB1
Jain, R; Rather, JA1
Akantappa Bandakkanavar, TK; Arora, P; Dash, A; Maiti, R1
Pshenkina, NN1
Bari, SB; Bhagwat, AM; Bhoir, SI; Dahivelkar, PP; Surana, SJ1
Demushkin, VP; Khaspekov, LG; Zhavoronkova, EV1
Ivshina, IB; Karpenko, JN; Mukhutdinova, AN; Richkova, MI; Vikhareva, EV1
Ilič, I; Kása, P; Papós, K; Pintye-Hódi, K; Sovány, T; Srčič, S1
Chikunova, BZ; Fadeeva, NA; Gubina, AV; Khomeriki, SG; Parfenov, AI; Poleva, NI; Ruchkina, IN; Shcherbakov, PL1
Efremov, LI; Firsova, LD; Ianova, OB; Kostiuchenko, LN; Pichugina, IM; Vasnev, OS1
Adel, S; ElKasabgy, NA1
Abdellatif, MA; Alzeeniny, HA; Ellaithy, MI; Ibrahim, MI; Salama, AH1
El Sibai, O; Shafik, AA; Shafik, IA1
Borka-Balás, R; Donáth-Nagy, G; Gáll, Z; Vancea, S1
El'-Registan, GI; Ivshina, IB; Mukhutdinova, AN; Mulyukin, AL; Suzina, NE; Tyumina, HA; Vikhareva, HV1
Babinets', AI; Babinets', LS; Droniak, IuV; Pliashko, KO1
Bałkota, M; Tomaszewski, D1
Sathiyasekaran, M1
Aggarwal, V1
Akhtar, H; Narang, M; Shah, D1
Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S1
Lajtai, A; Lakatos, Á; Mayer, M; Miseta, A; Porpáczy, Z1
Guttman, A; Mikus, EG; Patai, Z2
Al-Harrasi, A; Csuk, R; Heller, L; Loesche, A; Pavel, IZ; Sommerwerk, S1
Qi, XX; Wan, XY; Xue, XC1
Liu, J; Wang, JK1
Ahmad, B; Anwar, F; Ismail, T; Nazir, S; Raza, Z; Rehman, AU; Saleem, U; Sanawar, M1
Rzymski, P; Tomczyk, KM; Wilczak, M1
Badawy, AA; Elmalak, NSA; Farag, MM; Louis, MM; Nessem, DI1
Dimejesi, IB; Ekwunife, IC; Ikeotuonye, AC; Nwafor, JI; Ojumah, BO; Umeora, OJ1
A Abdel Salam, R; Abdelshakour, MA; Attala, K; E Mostafa, A; Eissa, MS; Elsonbaty, A; M Hadad, G1

Reviews

2 review(s) available for papaverine and drotaverin

ArticleYear
[Mechanisms of the therapeutic action of vasodilator agents in cardiac insufficiency (review of the literature)].
    Vrachebnoe delo, 1981, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Coronary Disease; Dogs; Heart Failure; Humans; Muscle Relaxants, Central; Nitroglycerin; Papaverine; Parasympatholytics; Phentolamine; Rabbits; Rats; Vasodilator Agents

1981
[Safety profile of NO-SPA].
    Orvosi hetilap, 2002, Mar-17, Volume: 143, Issue:11

    Topics: Analgesics; Humans; Papaverine; Parasympatholytics; Vasodilator Agents

2002

Trials

24 trial(s) available for papaverine and drotaverin

ArticleYear
Intra-arterial use of No-Spa+lidocaine in coxarthrosis.
    Therapia Hungarica (English edition), 1982, Volume: 30, Issue:3

    Topics: Clinical Trials as Topic; Hip Joint; Humans; Injections, Intra-Arterial; Lidocaine; Osteoarthritis; Papaverine; Parasympatholytics

1982
[Rheohepatographic changes under the effect of clinical trials of drugs in chronic nonspecific lung diseases].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:7

    Topics: Aminophylline; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; Ephedrine; Humans; Isoproterenol; Liver Circulation; Papaverine; Plethysmography, Impedance; Pneumonia; Strophanthins

1980
Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2001, Volume: 74, Issue:3

    Topics: Cervix Uteri; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics; Pregnancy; Quaternary Ammonium Compounds; Sympatholytics; Time Factors

2001
[Preparation no-shpa forte for the treatment of renal colic].
    Klinichna khirurhiia, 2003, Issue:2

    Topics: Adult; Aged; Colic; Female; Hemodynamics; Humans; Kidney Diseases; Male; Middle Aged; Papaverine; Parasympatholytics; Treatment Outcome

2003
The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones.
    BJU international, 2003, Volume: 92, Issue:1

    Topics: Acute Disease; Adult; Colic; Double-Blind Method; Female; Humans; Kidney Calculi; Male; Pain Measurement; Papaverine; Parasympatholytics; Treatment Outcome; Ureteral Calculi

2003
Drotaverine hydrochloride for augmentation of labor.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2004, Volume: 84, Issue:1

    Topics: Adult; Analgesia, Obstetrical; Analgesics; Cervix Uteri; Double-Blind Method; Female; Humans; Labor Stage, First; Labor, Obstetric; Pain Measurement; Papaverine; Parasympatholytics; Postpartum Hemorrhage; Pregnancy

2004
[Using prostaglandin inhibitor dicloberl in patients with ureteral calculi].
    Likars'ka sprava, 2004, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Diclofenac; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain; Papaverine; Parasympatholytics; Prostaglandin Antagonists; Tramadol; Treatment Outcome; Ureteral Calculi

2004
Bioavailability study of drotaverine from capsule and tablet preparations in healthy volunteers.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:5

    Topics: Adult; Area Under Curve; Biological Availability; Calibration; Capsules; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Male; Papaverine; Parasympatholytics; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets

2004
[Functional state of kidneys and upper urogenital tract in patients with intraligamentary ovarian cysts in pre and postoperative periods during the treatment with spasmolytics].
    Georgian medical news, 2006, Issue:139

    Topics: Adult; Female; Female Urogenital Diseases; Humans; Ovarian Cysts; Papaverine; Parasympatholytics; Postoperative Care; Preoperative Care; Renal Artery; Ultrasonography; Urodynamics

2006
[Vegetotropic therapy and hypobaric hypoxic adaptation in gallbladder motor dysmotility].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2007, Issue:3

    Topics: Adaptation, Physiological; Adolescent; Adrenergic beta-Antagonists; Adult; Autonomic Nervous System; Biliary Dyskinesia; Cholecystography; Dopamine Antagonists; Female; Gallbladder; Gallbladder Emptying; Humans; Hypoxia; Male; Metoclopramide; Middle Aged; Papaverine; Parasympatholytics; Propranolol; Treatment Outcome; Ultrasonography

2007
Drotaverine hydrochloride versus hyoscine-N-butylbromide in augmentation of labor.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2008, Volume: 100, Issue:3

    Topics: Adult; Butylscopolammonium Bromide; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics; Pregnancy; Prospective Studies

2008
Study of drotaverine on first stage of labour and pregnancy outcome.
    Journal of the Indian Medical Association, 2007, Volume: 105, Issue:8

    Topics: Drug-Related Side Effects and Adverse Reactions; Female; Humans; Labor Onset; Labor Stage, First; Labor, Obstetric; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Pregnancy; Pregnancy Outcome; Prospective Studies

2007
[Comparative efficacy and tolerability of drotaverine 80 mg and ibuprofen 400 mg in patients with primary dysmenorrhoea--protocol DOROTA].
    Ginekologia polska, 2007, Volume: 78, Issue:12

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dysmenorrhea; Female; Humans; Ibuprofen; Pain Measurement; Papaverine; Patient Satisfaction; Poland; Treatment Outcome; Women's Health

2007
[Dynamics of indices of visceral sensitivity in patients with irritable bowel syndrome treated with spasmolytics].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2007, Issue:6

    Topics: Abdominal Pain; Adult; Butylscopolammonium Bromide; Female; Humans; Hyperalgesia; Irritable Bowel Syndrome; Male; Pain Measurement; Pain Threshold; Papaverine; Parasympatholytics; Surveys and Questionnaires; Treatment Outcome; Viscera

2007
Interactions between symptoms and motor and visceral sensory responses of irritable bowel syndrome patients to spasmolytics (antispasmodics).
    Journal of gastrointestinal and liver diseases : JGLD, 2009, Volume: 18, Issue:1

    Topics: Administration, Oral; Administration, Rectal; Adult; Butylscopolammonium Bromide; Calcium Gluconate; Calendula; Colon, Sigmoid; Diarrhea; Female; Gastrointestinal Motility; Humans; Irritable Bowel Syndrome; Male; Motor Neurons; Pain; Pain Measurement; Papaverine; Parasympatholytics; Plant Preparations; Rectum; Sensory Receptor Cells; Severity of Illness Index; Suppositories; Tablets; Treatment Outcome; Young Adult

2009
Comparison of efficacy of oral drotaverine plus mefenamic acid with paracervical block and with intravenous sedation for pain relief during hysteroscopy and endometrial biopsy.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Analgesics; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anesthetics, Intravenous; Diazepam; Drug Therapy, Combination; Endometrium; Female; Humans; Hypnotics and Sedatives; Hysteroscopy; Mefenamic Acid; Middle Aged; Pain Measurement; Papaverine; Pentazocine; Treatment Outcome; Young Adult

2009
A randomised controlled study comparing Drotaverine hydrochloride and Valethamate bromide in the augmentation of labour.
    Archives of gynecology and obstetrics, 2010, Volume: 282, Issue:1

    Topics: Adult; Cervical Ripening; Cervix Uteri; Female; Humans; Injections, Intramuscular; Labor Stage, First; Papaverine; Parasympatholytics; Pregnancy; Pregnancy Outcome; Prospective Studies; Quaternary Ammonium Compounds; Time Factors; Young Adult

2010
Efficacy and safety of aceclofenac and drotaverine fixed-dose combination in the treatment of primary dysmenorrhoea: a double-blind, double-dummy, randomized comparative study with aceclofenac.
    European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 152, Issue:1

    Topics: Adolescent; Adult; Analgesics; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Combinations; Dysmenorrhea; Female; Humans; Papaverine; Phosphodiesterase Inhibitors; Treatment Outcome; Young Adult

2010
Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:3

    Topics: Adult; Analgesics; Diclofenac; Female; Humans; Injections, Intramuscular; Male; Pain Measurement; Papaverine; Renal Colic; Single-Blind Method

2012
[The role of small bowel microflora in the development of secondary lactase deficiency and the possibilities of its treatment with probiotics].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:2

    Topics: Adult; Analgesics; Bifidobacterium; Blind Loop Syndrome; Enterococcus faecium; Female; Humans; Intestine, Small; Irritable Bowel Syndrome; Lactase; Lactose Intolerance; Male; Papaverine; Probiotics; Treatment Outcome

2013
Drotaverine to improve progression of labor among nulliparous women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2014, Volume: 124, Issue:2

    Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; Papaverine; Parasympatholytics; Parity; Pregnancy; Time Factors; Young Adult

2014
Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study.
    BioMed research international, 2015, Volume: 2015

    Topics: Adolescent; Adult; Analgesics; Anesthesia, Epidural; Female; Humans; Injections, Intramuscular; Male; Papaverine; Parasympatholytics; Postoperative Complications; Premedication; Single-Blind Method; Treatment Outcome; Urinary Retention; Urination; Young Adult

2015
Efficacy and Safety of Drotaverine Hydrochloride in Children with Recurrent Abdominal Pain: A Randomized Placebo Controlled Trial.
    Indian pediatrics, 2015, Volume: 52, Issue:10

    Topics: Abdominal Pain; Absenteeism; Administration, Oral; Child; Child, Preschool; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; India; Male; Papaverine; Treatment Outcome

2015
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
    African health sciences, 2022, Volume: 22, Issue:3

    Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Labor Pain; Labor, Obstetric; Oxytocin; Papaverine; Pregnancy

2022

Other Studies

86 other study(ies) available for papaverine and drotaverin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity.
    Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Female; Isoquinolines; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; rho-Associated Kinases; Structure-Activity Relationship; Uterine Contraction

2018
[The usefulness of compartmental analysis for the development of sustained release drug forms; experiences with drotaverine in humans].
    Pharmaceutica acta Helvetiae, 1979, Volume: 54, Issue:7-8

    Topics: Delayed-Action Preparations; Humans; Models, Biological; Papaverine

1979
The intestinal absorption and excretion of 14C drotaverin in rats.
    European journal of drug metabolism and pharmacokinetics, 1979, Volume: 4, Issue:4

    Topics: Animals; Bile; Carbon Radioisotopes; Common Bile Duct; Intestinal Absorption; Intestine, Small; Ligation; Male; Papaverine; Rats; Time Factors

1979
[Prolonged liberation, by inclusion in an inert matrix, of drotaverine coprecipitate].
    Pharmaceutica acta Helvetiae, 1979, Volume: 54, Issue:12

    Topics: Delayed-Action Preparations; Papaverine; Parasympatholytics

1979
Effect of mepacrine on gastric motility in the rat.
    Acta physiologica Academiae Scientiarum Hungaricae, 1979, Volume: 53, Issue:3

    Topics: Administration, Oral; Animals; Bencyclane; Chloroquine; Female; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Injections, Intraperitoneal; Papaverine; Quinacrine; Rats

1979
[Practical significance of drug equivalence in preclinical research, with special reference to drotaverin and its salt with theophylline-7-acetic acid].
    Acta pharmaceutica Hungarica, 1979, Volume: 49, Issue:2

    Topics: Animals; Biological Availability; Drug Evaluation, Preclinical; Mice; Papaverine; Theophylline

1979
Data on the metabolism of benzylisoquinoline derivatives. The metabolism of drotaverin.
    Die Pharmazie, 1975, Volume: 30, Issue:3

    Topics: Animals; Benzyl Compounds; Feces; Isoquinolines; Mass Spectrometry; Papaverine; Rats; Spectrophotometry, Ultraviolet

1975
Comparative studies of drotaverine--acephyllinate (Depogen) and pentoxifylline (Trental).
    Thrombosis research, 1992, Jun-15, Volume: 66, Issue:6

    Topics: Animals; Cell Aggregation; Drug Combinations; Drug Evaluation, Preclinical; Erythrocytes; Humans; Leukocytes; Papaverine; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 3; Rabbits; Theophylline

1992
[The effect of food intake, atropine and No-spa on autonomic tonus and hemodynamic indices in patients with peptic ulcer].
    Vrachebnoe delo, 1989, Issue:10

    Topics: Adult; Atropine; Autonomic Nervous System; Duodenal Ulcer; Feeding Behavior; Female; Hemodynamics; Humans; Male; Middle Aged; Papaverine; Parasympatholytics

1989
[A case of Lyell's syndrome].
    Vrachebnoe delo, 1989, Issue:10

    Topics: Aged; Drug Combinations; Drug Therapy, Combination; Female; Humans; Papaverine; Parasympatholytics; Penicillins; Plant Extracts; Stevens-Johnson Syndrome

1989
[Preparation and in vitro study of suppositories containing No-Spa. I. Significance of choosing the basic substance. Determination of physical parameters of suppositories].
    Acta pharmaceutica Hungarica, 1989, Volume: 59, Issue:1

    Topics: Papaverine; Parasympatholytics; Vasodilator Agents

1989
[Preparation and in vitro study of suppositories containing No-Spa. II. Determination of release of the active principle by membrane diffusion methods].
    Acta pharmaceutica Hungarica, 1989, Volume: 59, Issue:1

    Topics: Diffusion; Drug Stability; Membranes, Artificial; Papaverine; Parasympatholytics; Suppositories; Vasodilator Agents

1989
[Use of no-shpa and phenicaberan in hypertonic biliary dyskinesia in patients with viral hepatitis].
    Vrachebnoe delo, 1988, Issue:11

    Topics: Adolescent; Adult; Benzofurans; Biliary Dyskinesia; Drug Evaluation; Hepatitis A; Hepatitis B; Humans; Middle Aged; Papaverine; Parasympatholytics

1988
[Hemodynamic indicators in patients with duodenal ulcer after pharmacological tests].
    Vrachebnoe delo, 1987, Issue:10

    Topics: Aluminum Hydroxide; Benzocaine; Drug Combinations; Duodenal Ulcer; Hemodynamics; Humans; Magnesium Hydroxide; Papaverine; Sorbitol

1987
A comparative study of two antispasmodic products: Buscopan and NO-Spa.
    East African medical journal, 1985, Volume: 62, Issue:7

    Topics: Animals; Butylscopolammonium Bromide; Disease Models, Animal; Guinea Pigs; Ileal Diseases; Papaverine; Parasympatholytics; Scopolamine Derivatives; Spasm

1985
Effect of prostaglandins and drotaverine on ADP-induced platelet aggregation.
    Acta medica Academiae Scientiarum Hungaricae, 1974, Volume: 31, Issue:3-4

    Topics: Adenosine Diphosphate; Blood Platelets; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Humans; Papaverine; Parasympatholytics; Platelet Aggregation; Prostaglandins E

1974
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
    Vestnik khirurgii imeni I. I. Grekova, 1982, Volume: 129, Issue:11

    Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Male; Middle Aged; Nicotinic Acids; Papaverine; Penicillins; Pentoxifylline; Povidone; Procaine; Promedol

1982
Neurogenic component in the effect of papaverine, drotaverine and bencyclane.
    Acta biologica Hungarica, 1983, Volume: 34, Issue:2-3

    Topics: Animals; Bencyclane; Calcium; Cycloheptanes; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Nalorphine; Naloxone; Papaverine; Parasympatholytics; Rana esculenta; Receptors, Opioid; Synapses; Synaptic Transmission

1983
[Biochemical basis for the spasmolytic effect of isoquinoline and phenothiazine derivatives].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:12

    Topics: Animals; In Vitro Techniques; Mitochondria, Muscle; Moricizine; Muscle, Smooth; Muscle, Smooth, Vascular; Nonachlazine; Oxygen Consumption; Papaverine; Parasympatholytics; Phenothiazines; Phosphorylation; Rats; Swine

1983
A new method for high-performance liquid chromatographic determination of drotaverine in plasma.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Papaverine; Parasympatholytics; Rats; Spectrophotometry, Ultraviolet

1984
Importance of No-Spa and Probon combination in the conservative treatment of ureterolithiasis patients.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:3

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Papaverine; Parasympatholytics; Pyrimidinones; Ureteral Calculi

1984
[The role of pharmacological tests in the early diagnosis of pulmonary hypertension].
    Vrachebnoe delo, 1983, Issue:8

    Topics: Aminophylline; Humans; Hypertension, Pulmonary; Papaverine; Time Factors

1983
Biopharmaceutical aspects of Depogen.
    Die Pharmazie, 1983, Volume: 38, Issue:9

    Topics: Animals; Biopharmaceutics; Diffusion; Dogs; Drug Combinations; Female; Male; Mice; Models, Biological; Papaverine; Rats; Theophylline

1983
[Clinical x-ray diagnosis of an elongated large intestine].
    Vrachebnoe delo, 1983, Issue:5

    Topics: Adult; Aged; Atropine; Chronic Disease; Diagnosis, Differential; Female; Gastrointestinal Neoplasms; Humans; Intestine, Large; Male; Middle Aged; Neostigmine; Palpation; Papaverine; Radiography

1983
Examination of the pain relieving-effect of intra-arterial No-Spa treatment of coxarthrosis.
    Therapia Hungarica (English edition), 1982, Volume: 30, Issue:2

    Topics: Adult; Aged; Female; Hip Joint; Humans; Injections, Intra-Arterial; Male; Middle Aged; Osteoarthritis; Pain; Papaverine; Parasympatholytics

1982
[Characteristic features of the functioning of arteriolovenular anastomoses in pharmacological arterial hyperemia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:11

    Topics: Aminophylline; Animals; Arterioles; Arteriovenous Anastomosis; Collateral Circulation; Hyperemia; Male; Mesentery; Papaverine; Rats; Rats, Inbred Strains; Venules

1982
Treatment of coxarthroses with intraarterial injection of No-Spa + Lidocaine.
    Therapia Hungarica (English edition), 1980, Volume: 28, Issue:4

    Topics: Female; Hip Joint; Humans; Injections, Intra-Arterial; Joint Diseases; Lidocaine; Male; Middle Aged; Papaverine

1980
[Use of No-Shpa in combination with vitamins in motion sickness].
    Kosmicheskaia biologiia i aviakosmicheskaia meditsina, 1981, Volume: 15, Issue:3

    Topics: Drug Evaluation; Drug Therapy, Combination; Humans; Motion Sickness; Papaverine; Placebos; Scopolamine; Vitamins

1981
[Changes in renal hemodynamics and renal function in patients with cardiac insufficiency treated with vasodilators].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:8

    Topics: Bencyclane; Dipyridamole; Heart Failure; Humans; Kidney; Papaverine; Renal Circulation; Vasodilator Agents

1981
Effects of drotaverin and depogen on gastric emptying in beagle dogs.
    Acta veterinaria Academiae Scientiarum Hungaricae, 1981, Volume: 29, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Drug Combinations; Female; Gastric Emptying; Male; Papaverine; Parasympatholytics; Theophylline

1981
Qualitative and quantitative determination of drotaverine metabolites in rat bile.
    European journal of drug metabolism and pharmacokinetics, 1980, Volume: 5, Issue:2

    Topics: Administration, Oral; Animals; Bile; Biotransformation; Chromatography, Thin Layer; Injections, Intravenous; Male; Papaverine; Parasympatholytics; Perfusion; Rats

1980
[Use of transcatheter intra-arterial infusion of drug mixtures in the combined treatment of patients with obliterating vascular diseases in the terminal stage of limb ischemia].
    Klinicheskaia khirurgiia, 1994, Issue:7

    Topics: Adult; Aged; Amputation, Surgical; Anti-Bacterial Agents; Arterial Occlusive Diseases; Ascorbic Acid; Combined Modality Therapy; Dextrans; Drug Combinations; Heparin; Humans; Infusions, Intra-Arterial; Ischemia; Leg; Middle Aged; Nicergoline; Papaverine; Pentoxifylline; Procaine; Vasodilator Agents; Vitamin B Complex

1994
High-performance liquid chromatographic method for the determination of drotaverine in human plasma and urine.
    Journal of chromatography, 1993, Dec-08, Volume: 622, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Male; Papaverine; Regression Analysis; Spectrophotometry, Ultraviolet; Sympatholytics

1993
[Effect of the drug no-spa on the status of the arterioles in rat skeletal muscles after total gamma-irradiation with a dose of 1 Gy].
    Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 117, Issue:3

    Topics: Animals; Arterioles; Gamma Rays; Male; Muscles; Papaverine; Rats; Rats, Wistar; Vasodilator Agents

1994
[Changes in the thermogram of the precordial area and the hands under the influence of the No-Shpa test in stenocardia patients].
    Likars'ka sprava, 1998, Issue:3

    Topics: Angina Pectoris; Body Temperature Regulation; Color; Hand; Hemodynamics; Humans; Male; Middle Aged; Papaverine; Thermography; Thorax; Time Factors; Vasodilator Agents

1998
[Interspecies allometric scaling in pharmacokinetics of drugs].
    Acta pharmaceutica Hungarica, 1998, Volume: 68, Issue:6

    Topics: Animals; Body Weight; Cats; Dogs; Drug Combinations; Humans; Mice; Organ Size; Papaverine; Parasympatholytics; Rats; Regression Analysis; Species Specificity; Theophylline; Tissue Distribution

1998
[Inhibiting effect of no-spa on paragrippe virus reproduction].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:3

    Topics: Animals; Anti-Infective Agents; Chick Embryo; Inhibitory Concentration 50; Papaverine; Paramyxoviridae; Virus Replication

1999
[Pseudopolymorphism of NO-SPA, 1-(3,4-diethoxy-benzyl)-6,7-diethoxy-3,4-dihydro-isoquinoli ne hydrochloride].
    Acta pharmaceutica Hungarica, 1999, Volume: 69, Issue:1

    Topics: Crystallography, X-Ray; Drug Stability; Models, Molecular; Molecular Conformation; Molecular Structure; Papaverine; Parasympatholytics

1999
Origin of rectal electric waves: further study.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:12

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Defecation; Dogs; Electrophysiology; Enteric Nervous System; Female; Ganglionectomy; Gastrointestinal Motility; Intestinal Mucosa; Male; Membrane Potentials; Muscle, Smooth; Papaverine; Parasympatholytics; Phentolamine; Pressure; Propranolol; Rectum

1999
Behavioural effects of selective PDE4 inhibitors in relation to inhibition of catalytic activity and competition for [3H]rolipram binding.
    Neurobiology (Budapest, Hungary), 1999, Volume: 7, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Binding, Competitive; Catalytic Domain; Cyclic Nucleotide Phosphodiesterases, Type 4; Papaverine; Parasympatholytics; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Tritium

1999
[Rare forms of partial gigantism due to vascular hypoplasia].
    Klinicheskaia khirurgiia, 1993, Issue:2

    Topics: Arm; Arteriovenous Malformations; Child, Preschool; Female; Gigantism; Humans; Leg; Papaverine; Radiography; Vasodilator Agents

1993
Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes.
    European journal of pharmacology, 2002, Aug-02, Volume: 449, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic Nucleotide Phosphodiesterases, Type 4; Diltiazem; Female; Half-Life; In Vitro Techniques; Kinetics; Membranes; Nitrendipine; Papaverine; Parasympatholytics; Phosphodiesterase Inhibitors; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Sprague-Dawley; Uterus

2002
[COMPARATIVE CLINICAL MEASUREMENT OF THE EFFECT OF SPASMOLYTIES. (DATA ON THE CLINICAL PHARMACOLOGY OF NO-SPA)].
    Orvosi hetilap, 1963, Oct-27, Volume: 104

    Topics: Cardiovascular Agents; Muscle Relaxants, Central; Papaverine; Pharmacology; Vasodilator Agents

1963
EXPERIENCE OBTAINED WITH A NEW SPASMOLYTIC DRUG (NO-SPA).
    Therapia Hungarica (English edition), 1963, Volume: 11

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cholelithiasis; Colic; Colitis; Duodenal Ulcer; Dysmenorrhea; Female; Humans; Kidney Calculi; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Peptic Ulcer; Quinolines

1963
COMPARATIVE CLINICAL STUDY OF THE POTENCY OF SPASMOLYTICS (OBSERVATIONS REGARDING THE CLINICAL PHARMACOLOGY OF NO-SPA).
    Therapia Hungarica (English edition), 1963, Volume: 11

    Topics: Humans; Injections, Intra-Arterial; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Pharmacology, Clinical; Vascular Diseases; Vasomotor System

1963
NO-SPA, A NEW SPASMOLYTIC FOR THE TREATMENT OF THROMBOEMBOLIC AFFECTIONS OF THE LOWER EXTREMITIES.
    Therapia Hungarica (English edition), 1965, Volume: 13

    Topics: Lower Extremity; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Quinolines; Thromboembolism

1965
[New approaches to diagnosing and treating hyperkinetic biliary dyskinesia associated with chronic acalculous cholecystitis].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:9

    Topics: Acalculous Cholecystitis; Adult; Biliary Dyskinesia; Calcium Channel Blockers; Chronic Disease; Female; Humans; Male; Middle Aged; Morpholines; Papaverine; Parasympatholytics; Quaternary Ammonium Compounds; Time Factors; Treatment Outcome; Ultrasonography

2004
Transport properties and electroanalytical response characteristics of drotaverine ion-selective sensors.
    Analytical and bioanalytical chemistry, 2005, Volume: 382, Issue:7

    Topics: Calibration; Electrochemistry; Ion-Selective Electrodes; Membranes, Artificial; Papaverine; Parasympatholytics; Permeability; Pharmaceutical Preparations; Polyvinyl Chloride; Potentiometry; Sensitivity and Specificity; Tablets; Time Factors

2005
Application of new membrane selective electrodes for the determination of drotaverine hydrochloride in tablets and plasma.
    Journal of pharmaceutical and biomedical analysis, 2006, Jun-07, Volume: 41, Issue:3

    Topics: Calibration; Electrodes; Humans; Papaverine; Parasympatholytics; Sensitivity and Specificity; Tablets

2006
A comparative study on various spectrometries with thin layer chromatography for simultaneous analysis of drotaverine and nifuroxazide in capsules.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:6

    Topics: Anti-Infective Agents; Calibration; Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Drug Stability; Hydroxybenzoates; Methanol; Nitrofurans; Papaverine; Pharmaceutical Preparations; Reference Standards; Spectrophotometry; Spectrophotometry, Ultraviolet; Spectrum Analysis

2006
Spectrophotometric and spectrodensitometric determination of paracetamol and drotaverine HCl in combination.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 66, Issue:4-5

    Topics: Acetaminophen; Chromatography, Thin Layer; Densitometry; Hydrochloric Acid; Papaverine; Reproducibility of Results; Spectrophotometry, Ultraviolet

2007
Spectrophotometric determination of pipazethate HCl, dextromethorphan HBr and drotaverine HCl in their pharmaceutical preparations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 67, Issue:3-4

    Topics: Antitussive Agents; Benzothiadiazines; Calibration; Chloroform; Dextromethorphan; Dose-Response Relationship, Drug; Methylene Chloride; Molecular Structure; Naphthalenesulfonates; Papaverine; Pharmaceutical Preparations; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Time Factors; Water

2007
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
    Clinical hemorheology and microcirculation, 2007, Volume: 36, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2007
Simultaneous determination of nifuroxazide and drotaverine hydrochloride in pharmaceutical preparations by bivariate and multivariate spectral analysis.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Volume: 69, Issue:2

    Topics: Hydroxybenzoates; Multivariate Analysis; Nitrofurans; Papaverine; Pharmaceutical Preparations; Spectrophotometry

2008
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
    Clinical hemorheology and microcirculation, 2008, Volume: 40, Issue:2

    Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids

2008
Cathodic adsorptive stripping voltammetry of drotaverine hydrochloride and its determination in tablets and human urine by differential pulse voltammetry.
    Bioelectrochemistry (Amsterdam, Netherlands), 2009, Volume: 75, Issue:1

    Topics: Adsorption; Calibration; Chemistry Techniques, Analytical; Humans; Hydrogen-Ion Concentration; Molecular Structure; Papaverine; Tablets

2009
Voltammetric behaviour of drotaverine hydrochloride in surfactant media and its enhancement determination in Tween-20.
    Colloids and surfaces. B, Biointerfaces, 2011, Feb-01, Volume: 82, Issue:2

    Topics: Adsorption; Carbon; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Models, Chemical; Papaverine; Polysorbates; Reproducibility of Results; Surface Properties; Surface-Active Agents; Tablets

2011
[Influence of Perftoran nanoemulsion on blood plasma concentrations of lipophilic drugs].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:2

    Topics: Animals; Benzimidazoles; Blood Substitutes; Fluorocarbons; Hydrophobic and Hydrophilic Interactions; Ketorolac; Male; Papaverine; Protein Binding; Rabbits; Verapamil

2012
Simultaneous determination of diclofenac potassium and drotaverine hydrochloride in human plasma using reversed-phase high-performance liquid chromatography.
    Journal of chromatographic science, 2012, Volume: 50, Issue:8

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diclofenac; Humans; Least-Squares Analysis; Liquid-Liquid Extraction; Papaverine; Reproducibility of Results; Sensitivity and Specificity

2012
Effects of drotaverine hydrochloride on viability of rat cultured cerebellar granulocytes.
    Bulletin of experimental biology and medicine, 2012, Volume: 152, Issue:4

    Topics: Animals; Animals, Newborn; Cell Survival; Cerebellum; Dose-Response Relationship, Drug; Granulocytes; Molecular Structure; Papaverine; Parasympatholytics; Primary Cell Culture; Rats

2012
Biodegradation of drotaverine hydrochloride by free and immobilized cells of Rhodococcus rhodochrous IEGM 608.
    World journal of microbiology & biotechnology, 2012, Volume: 28, Issue:10

    Topics: Biodegradation, Environmental; Biotransformation; Cells, Immobilized; Culture Media; Gas Chromatography-Mass Spectrometry; Papaverine; Rhodococcus

2012
Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics.
    AAPS PharmSciTech, 2013, Volume: 14, Issue:2

    Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Computer Simulation; Lactose; Mannitol; Models, Chemical; Neural Networks, Computer; Papaverine; Pharmaceutical Preparations; Powders; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength

2013
[Nutricional support in the complex treatment of a patient with esophageal spasm].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2013, Issue:2

    Topics: Antidepressive Agents; Benzodiazepines; Combined Modality Therapy; Drug Therapy, Combination; Enteral Nutrition; Esophageal Spasm, Diffuse; Female; Humans; Middle Aged; Papaverine; Parasympatholytics; Treatment Outcome

2013
Design of innovated lipid-based floating beads loaded with an antispasmodic drug: in-vitro and in-vivo evaluation.
    Journal of liposome research, 2014, Volume: 24, Issue:2

    Topics: Adult; Alginates; Animals; Diarrhea; Dogs; Drug Delivery Systems; Emulsions; Glucuronic Acid; Hexuronic Acids; Humans; Liposomes; Methylcellulose; Myristates; Papaverine; Parasympatholytics; Pharmaceutical Preparations; Triglycerides

2014
On the etiology of the electric activity of the external anal and urethral sphincters.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2014, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Anal Canal; Animals; Child; Dogs; Electromyography; Female; Humans; Infant, Newborn; Male; Middle Aged; Muscle Fibers, Skeletal; Myocytes, Smooth Muscle; Nerve Block; Papaverine; Parasympatholytics; Urethra; Young Adult

2014
Rapid LC-MS/MS method for determination of drotaverine in a bioequivalence study.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Chromatography, Liquid; Humans; Imipramine; Methanol; Papaverine; Plasma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Therapeutic Equivalency

2014
Drotaverine hydrochloride degradation using cyst-like dormant cells of Rhodococcus ruber.
    Current microbiology, 2015, Volume: 70, Issue:3

    Topics: Biodegradation, Environmental; Culture Media; Environmental Pollutants; Papaverine; Rhodococcus; Temperature

2015
[Efficiency of etiologic correction of concomitant ascaridosis in the complex treatment of chronic pancreatitis].
    Likars'ka sprava, 2014, Issue:11

    Topics: Abdominal Pain; Albendazole; Analgesics; Animals; Anthelmintics; Ascariasis; Ascaris; Drug Therapy, Combination; Dysbiosis; Dyspepsia; Feces; Female; Gastrointestinal Agents; Humans; Male; Pancreas; Pancreatitis, Chronic; Pancrelipase; Papaverine; Treatment Outcome

2014
Management of Recurrent Abdominal Pain: Have we Reached the end of the Tunnel?
    Indian pediatrics, 2015, Volume: 52, Issue:10

    Topics: Abdominal Pain; Chronic Pain; Female; Gastrointestinal Diseases; Humans; Male; Papaverine

2015
Drotaverine for Recurrent Abdominal Pain in Children.
    Indian pediatrics, 2015, Volume: 52, Issue:10

    Topics: Abdominal Pain; Chronic Pain; Female; Gastrointestinal Diseases; Humans; Male; Papaverine

2015
Evaluation of the efficiency of continuous wavelet transform as processing and preprocessing algorithm for resolution of overlapped signals in univariate and multivariate regression analyses; an application to ternary and quaternary mixtures.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, 07-05, Volume: 164

    Topics: Acetaminophen; Algorithms; Aminophenols; Analgesics; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Multivariate Analysis; Papaverine; Spectrophotometry; Wavelet Analysis

2016
Embutramide, a Component of Tanax(®) (T-61) as a New Drug of Abuse?
    Journal of forensic sciences, 2016, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Alprazolam; Amides; Drug Combinations; Humans; Male; Papaverine; Quaternary Ammonium Compounds; Substance-Related Disorders; Tetracaine

2016
Potential L-Type Voltage-Operated Calcium Channel Blocking Effect of Drotaverine on Functional Models.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 359, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Electrophysiological Phenomena; Guinea Pigs; Male; Muscle Contraction; Papaverine; Potassium Chloride; Trachea

2016
Drotaverine - a Concealed Cytostatic!
    Archiv der Pharmazie, 2017, Volume: 350, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mice; Papaverine; Tetrahydroisoquinolines

2017
Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine.
    Pharmacology, 2018, Volume: 101, Issue:3-4

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Trachea

2018
Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome.
    Medicine, 2017, Volume: 96, Issue:51

    Topics: Administration, Oral; Adult; Aged; Chi-Square Distribution; China; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pain Measurement; Papaverine; Patient Safety; Risk Assessment; Severity of Illness Index; Single-Blind Method; Statistics, Nonparametric; Treatment Outcome; Young Adult

2017
Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome: A retrospective study.
    Medicine, 2018, Volume: 97, Issue:29

    Topics: Adult; Combined Modality Therapy; Diarrhea; Electric Stimulation Therapy; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Papaverine; Parasympatholytics; Retrospective Studies; Treatment Outcome; Visual Analog Scale

2018
Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice.
    Neurochemical research, 2021, Volume: 46, Issue:7

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cognitive Dysfunction; Female; Learning; Male; Memory; Mice; Molecular Docking Simulation; Morris Water Maze Test; Neurotransmitter Agents; Nootropic Agents; Open Field Test; Papaverine; Phosphodiesterase 4 Inhibitors; Protein Binding; Streptozocin

2021
The Influence of Oral Drotaverine Administration on Materno-Fetal Circulation during the Second and Third Trimester of Pregnancy.
    Medicina (Kaunas, Lithuania), 2022, Feb-03, Volume: 58, Issue:2

    Topics: Administration, Oral; Female; Humans; Infant, Newborn; Papaverine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Premature Birth; Prospective Studies; Ultrasonography, Prenatal

2022
Drotaverine Hydrochloride Superporous Hydrogel Hybrid System: a Gastroretentive Approach for Sustained Drug Delivery and Enhanced Viscoelasticity.
    AAPS PharmSciTech, 2022, Apr-26, Volume: 23, Issue:5

    Topics: Biological Availability; Drug Delivery Systems; Hydrogels; Papaverine

2022
Computer-Aided Design of Eco-Friendly Imprinted Polymer Decorated Sensors Augmented by Self-Validated Ensemble Modeling Designs for the Quantitation of Drotaverine Hydrochloride in Dosage Form and Human Plasma.
    Journal of AOAC International, 2023, Sep-01, Volume: 106, Issue:5

    Topics: Computer-Aided Design; Humans; Papaverine; Polymers

2023