Compounds > papaverine

papaverine and diazoxide

papaverine has been researched along with diazoxide in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (47.37)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (15.79)	29.6817
2010's	7 (36.84)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Sen, AK; Sunahara, FA; Talesnik, J	1
Sharma, PL; Singh, M	2
Peguet, MF; Stoclet, JC; Waedele, G	1
Bolan, J; Daniel, EE; Polacek, I	1
Andersson, R	1
Hausler, LM; Roth, FE; Wohl, AJ	1
Albrecht, T; Speelman, DJ; Steinsland, OS	1
García de Boto, MJ; Hidalgo, A; Martínez, C; Sánchez, M	1

Reviews

1 review(s) available for papaverine and diazoxide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

18 other study(ies) available for papaverine and diazoxide

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Coronary reactions to cardiac hyperactivity and to hypoxia in isolated perfused heart of rat. British journal of pharmacology, 1977, Volume: 61, Issue:3 Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Cyclic AMP; Diazoxide; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Norepinephrine; Papaverine; Perfusion; Prostaglandins E; Rats; Reserpine; Vasodilation	1977
Effect of cyclic nucleotide phosphodiesterase regulators on isolated rat uterus: with observations on their mechanism of action. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 273, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminophylline; Animals; Bucladesine; Calcium; Catecholamines; Cyclic AMP; Diazoxide; Female; Imidazoles; In Vitro Techniques; Papaverine; Potassium Chloride; Rats; Rats, Inbred Strains; Uterine Contraction	1985
[Influence of metacorticoid hypertension on sensitivity of the isolated rat aorta to Ba2 ions and to papaverine]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Volume: 164, Issue:6 Topics: Animals; Aorta; Barium; Calcium; Diazoxide; Hypertension; Mineralocorticoids; Papaverine; Rats	1970
Accumulation of adenosine 3',5'-monophosphate and relaxation in the rat uterus in vitro. Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:11 Topics: Animals; Butyrates; Cyclic AMP; Depression, Chemical; Diazoxide; Drug Interactions; Female; Fluorides; Imidazoles; In Vitro Techniques; Muscle Contraction; Papaverine; Phosphoric Diester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Theophylline; Uterus	1971
Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine, diazoxide and hydralazine in intestinal and vascular smooth muscle. Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:5 Topics: Adenosine Triphosphate; Animals; Arteries; Calcium; Cattle; Colon; Cyclic AMP; Diazoxide; Hydralazine; In Vitro Techniques; Muscle, Smooth; Nitroglycerin; Papaverine; Phosphocreatine; Phosphoric Diester Hydrolases; Rabbits; Stimulation, Chemical; Subcellular Fractions; Time Factors	1973
Studies on the mechanism of antihypertensive action of diazoxide: in vitro vascular pharmacodynamics. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:3 Topics: Animals; Aorta; Barium; Blood Pressure; Calcium; Diazoxide; Drug Antagonism; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Norepinephrine; Papaverine; Phenoxybenzamine; Phentolamine; Rats; Receptors, Drug; Vasoconstrictor Agents	1967
Similarities between cytomegalovirus-induced cell rounding and contraction of smooth muscle cells. Life sciences, 1983, May-09, Volume: 32, Issue:19 Topics: Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Diazoxide; Fibroblasts; Humans; Hydralazine; Muscle Contraction; Muscle, Smooth; Nitroprusside; Papaverine; Verapamil	1983
Effect of phosphodiesterase regulators on prostaglandin evoked responses in isolated rat uterus. Indian journal of experimental biology, 1984, Volume: 22, Issue:12 Topics: Aminophylline; Animals; Diazoxide; Female; Imidazoles; In Vitro Techniques; Myometrium; Papaverine; Phosphodiesterase Inhibitors; Prostaglandins; Rats; Rats, Inbred Strains	1984
Involvement of K(ATP) channels in diethylstilbestrol-induced relaxation in rat aorta. European journal of pharmacology, 2001, Feb-09, Volume: 413, Issue:1 Topics: Animals; Aorta; Colforsin; Cyclic AMP; Diazoxide; Diethylstilbestrol; Dose-Response Relationship, Drug; Eflornithine; Glyburide; In Vitro Techniques; Indoles; Male; Muscle, Smooth, Vascular; Norepinephrine; Papaverine; Potassium Channels; Rats; Rats, Wistar; Spermine; Tamoxifen; Tetraethylammonium; Vasoconstriction; Vasodilation; Vasodilator Agents	2001