pantothenic acid and n-pentylpantothenamide

pantothenic acid has been researched along with n-pentylpantothenamide in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auclair, K; Barnard, L; Chang, JH; Cresson, J; Guan, J; Hoegl, A; Strauss, E1
Begley, TP; Strauss, E1
Brand, LA; Strauss, E1
Cronan, JE; Thomas, J1
Bolshan, Y; Li, B; Park, HW; Schapira, M; Smil, D; Tempel, W1
Auclair, K; Awuah, E; Habib, E; Hoegl, A; Ma, E; Vong, K1
Arnott, ZLP; Monteiro, DCF; Morgan, HE; Niki, H; Nozaki, S; Pearson, AR; Webb, ME1

Other Studies

7 other study(ies) available for pantothenic acid and n-pentylpantothenamide

ArticleYear
Probing the ligand preferences of the three types of bacterial pantothenate kinase.
    Bioorganic & medicinal chemistry, 2018, 12-01, Volume: 26, Issue:22

    Topics: Anti-Bacterial Agents; Bacillus anthracis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Ligands; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Structure-Activity Relationship

2018
The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite.
    The Journal of biological chemistry, 2002, Dec-13, Volume: 277, Issue:50

    Topics: Anti-Bacterial Agents; Base Sequence; Chromatography, High Pressure Liquid; Coenzyme A; DNA Primers; Escherichia coli; Microbial Sensitivity Tests; Pantothenic Acid

2002
Characterization of a new pantothenate kinase isoform from Helicobacter pylori.
    The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21

    Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Bacillus subtilis; Cloning, Molecular; Coenzyme A; Enzyme Inhibitors; Gene Expression; Helicobacter pylori; Isoenzymes; Kinetics; Molecular Sequence Data; Multigene Family; NAD; Oxidation-Reduction; Pantothenic Acid; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Folding; Sequence Alignment

2005
Antibacterial activity of N-pentylpantothenamide is due to inhibition of coenzyme a synthesis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Acyl Carrier Protein; Anti-Bacterial Agents; Coenzyme A; Escherichia coli K12; Escherichia coli Proteins; Microbial Sensitivity Tests; Pantothenic Acid; Phosphoric Diester Hydrolases

2010
Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
    Proteins, 2013, Volume: 81, Issue:8

    Topics: Binding Sites; Crystallography, X-Ray; Klebsiella pneumoniae; Models, Molecular; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor)

2013
Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase.
    Bioorganic & medicinal chemistry, 2014, Jun-15, Volume: 22, Issue:12

    Topics: Catalytic Domain; Coenzyme A; Escherichia coli; Models, Molecular; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Structure-Activity Relationship

2014
The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZ·AcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan).
    Biochemistry, 2017, 09-19, Volume: 56, Issue:37

    Topics: Acetyl Coenzyme A; Amino Acid Substitution; Anti-Bacterial Agents; Antimetabolites; Binding Sites; Calorimetry; Carboxy-Lyases; Coenzyme A; Crystallography, X-Ray; Enzyme Activation; Escherichia coli K12; Escherichia coli Proteins; Gene Deletion; Glutamate Decarboxylase; Kinetics; Models, Molecular; Mutation; Pantothenic Acid; Protein Conformation; Protein Multimerization; Recombinant Proteins; Titrimetry

2017