pantothenic acid has been researched along with coenzyme a in 290 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 183 (63.10) | 18.7374 |
| 1990's | 15 (5.17) | 18.2507 |
| 2000's | 33 (11.38) | 29.6817 |
| 2010's | 42 (14.48) | 24.3611 |
| 2020's | 17 (5.86) | 2.80 |
| Authors | Studies |
|---|---|
| Banns, H; Hebb, C; Mann, SP | 1 |
| Brohn, FH; Trager, W | 2 |
| Knowles, CL; Lyman, EM; Sribney, M | 2 |
| Dunn, SD; Snell, EE | 1 |
| Halvorsen, O; Skrede, S | 3 |
| Trager, W | 1 |
| Ogata, K; Shimizu, S; Tani, Y | 1 |
| Hassinen, IE; Jauhonen, VP; Savolainen, MJ; Voltti, H | 1 |
| Cano, ML; Potyraj, J; Smith, CM | 1 |
| Smith, CM | 1 |
| Liteplo, RG; Sribney, M | 1 |
| Adson, MA; Ellestad-Sayed, JJ; Nelson, RA; Palmer, WM; Soule, EH | 1 |
| Bruckner, DA; Jaffe, J; Meymarian, E; Voge, M | 1 |
| Master, BS; Roeder, SB; Stewart, CJ | 1 |
| Hauhart, RE; Thurston, JH | 2 |
| Huth, W; Möller, U; Worm-Breitgoff, C; Wunderlich, I | 1 |
| Beinlich, CJ; Tahiliani, AG | 1 |
| Beinlich, CJ; Neely, JR; Robishaw, JD | 1 |
| Hansen, RG; Pearson, J; Schweitzer, C; Song, WO; Windham, CT; Wittwer, CT; Wyse, BW | 1 |
| Rock, CO; Vallari, DS | 3 |
| Campbell, EH; Fixter, LM; McAllister, RA | 1 |
| Neely, JR; Robishaw, JD | 2 |
| Iannucci, J; Israel, BC; Marino, KA; Smith, CM | 1 |
| Brambl, R; Plesofsky-Vig, N | 1 |
| Spector, R | 1 |
| Hobara, N; Nagashima, H; Watanabe, A | 1 |
| Israel, BC; Smith, CM | 1 |
| Moĭseenok, AG; Petrov, VN; Rybalko, MA; Tsverbaum, EA | 1 |
| Gurinovich, VA; Moiseenok, AG; Sheibak, VM | 1 |
| Kendrick, ZV; Narrow, CM; Smith, CM; Steffen, C | 1 |
| Aberhart, DJ; Cotting, JA; Ghoshal, PK; Russell, DJ | 1 |
| Roncari, DA | 1 |
| Bloch, K; Kawaguchi, A | 1 |
| Domont, C | 1 |
| Andrieux-Domont, C | 2 |
| Miller, TL; Stewart, CJ | 1 |
| Benedict, CR; Cooper, TC | 1 |
| Abiko, Y; Ashida, SI; Shimizu, M | 1 |
| Arthur, LO; Kaneshiro, T; Nickerson, KW | 1 |
| Alworth, WL; Plaut, GW; Smith, CM | 1 |
| Shimizu, M | 3 |
| Hesse, C; Hötzel, D; Pietrzik, K; Schulze zur Wiesch, E | 1 |
| Podack, ER; Saathoff, G | 1 |
| Burton, DN; Yu, HL | 1 |
| Prescott, DJ; Vagelos, PR | 1 |
| Muhsam-Peled, O; Razin, S; Rottem, S | 1 |
| Nakamura, H; Tamura, Z | 1 |
| Lornitzo, FA; Porter, JW; Qureshi, AA | 2 |
| Buckel, W; Eggerer, H | 1 |
| Hancock, WS; Marshall, GR; Prescott, DJ; Vagelos, PR | 1 |
| Bellussi, L; Cavallini, D; Del Grosso, E; Duprè, S; Rosei, MA | 1 |
| Vagelos, PR; Volpe, JJ | 1 |
| Roskoski, R | 1 |
| Chibata, I; Kakimoto, T; Nishimura, N; Shibatani, T | 1 |
| Kirk, JE | 1 |
| Elovson, J; Vagelos, PR | 1 |
| Lynen, F | 1 |
| Matsuzaki, F; Nishizawa, Y | 1 |
| Elovson, J; Prescott, DJ; Vagelos, PR | 1 |
| Elovson, J; Powell, GL; Vagelos, PR | 1 |
| Abiko, Y; Hosokawa, Y; Nagase, O; Shimizu, M; Suzuki, T | 2 |
| Arvy, L | 1 |
| Lipmann, F | 2 |
| Lynen, F; Schweizer, E; Willecke, K; Winnewisser, W | 1 |
| Edwards, J; Lane, MD; Moss, J; Stoll, E | 1 |
| Das, DN; Feng, F; Toennies, G | 1 |
| Das, DN; Toennies, G | 1 |
| Galecka, H; Iwanowska, J | 1 |
| Kusunoki, T; Kuwagata, M; Nakamura, T; Soyama, K | 1 |
| Larrabee, AR; Tweto, J | 1 |
| Furukawa, K; Hosoki, K; Karasawa, T; Yoshida, K | 1 |
| Miyata, K; Ogata, K; Shimizu, S; Tani, Y | 1 |
| Fidanza, A | 1 |
| Lynen, F; Schultz, J; Wells, WW | 2 |
| Ting, SM; Wu, YN | 1 |
| Nagasaka, Y; Osumi, Y; Shimamoto, K | 1 |
| Aida, K; Tokuyama, T; Uemura, T | 1 |
| Alberts, AW; Vagelos, PR | 1 |
| Tedo, T | 1 |
| Rozanov, AIa; Savluchinskaia, LG | 1 |
| Alexandre, A; Galzigna, L; Gibson, DM; Rossi, CR; Sartorelli, L | 1 |
| Nakamura, T; Nomoto, N; Oya, N; Yagi, R | 1 |
| Kroeplin-Rueff, L; Lerch, I; Lynen, F; Schweizer, E | 1 |
| Kopelevich, VM; Rozanov, AIa; Savluchinskaia, LG; Zhdanovich, ES | 1 |
| Gorenshteĭn, BI; Gritsenko, EA; Moĭseenok, AG; Ostrovskiĭ, IuM; Trebukhina, RV | 1 |
| Little, C; O'Brien, PJ; Olinescu, RM | 1 |
| Larrabee, AR; Liberati, M; Tweto, J | 1 |
| Kataoka, S; Kusunoki, T; Masugi, I; Nakamura, T; Soyama, K | 1 |
| Kusunoki, T; Nakamura, T; Soyama, K | 1 |
| Ieranò, A; Mascitelli Coriandoli, E | 1 |
| De Nicola, P; Gibelli, A | 1 |
| Chu, LC; Hincenbergs, I; McIntosh, DJ; Williams, MA | 1 |
| Nelson, RA | 1 |
| Abramovitz, AS; Butterworth, PH; Chesterton, CJ; Jacob, EJ; Porter, JW | 1 |
| Aguirre, AR; Ball, WJ; Stewart, CJ; Thomas, JO | 1 |
| Fales, HA; Gal, AE; Trams, EG | 1 |
| Ieranò, A; Mascitelli-Coriandoli, E | 1 |
| Coppi, M; De Nicola, P; Montanaro, G | 1 |
| Huan, PH; Hung, LV | 1 |
| Hosokawa, Y; Nagase, O; Shimizu, M | 1 |
| Jones, DH; Nelson, WL | 1 |
| Abiko, Y; Shimizu, M | 1 |
| Hosokawa, Y; Nagase, O; Okada, S; Shimizu, M; Tagawa, H | 1 |
| Hurley, LS; Volkert, NE | 1 |
| Lund, PG; Shorb, MS | 1 |
| Alpert, A; Kisliuk, RL; Shuster, L | 1 |
| Bigler, F; Thölen, H | 1 |
| Nakajima, T; Samejima, K; Tamura, Z | 1 |
| L'vova, LE | 1 |
| Kanematsu, Y | 3 |
| Scrutton, MC; Utter, MF | 1 |
| Barna, K; Wessela, E | 1 |
| Srere, PA | 1 |
| Abiko, Y | 2 |
| Abiko, Y; Shimizu, M; Suzuki, T | 1 |
| Ailhaud, GP; Goldfine, H; Vagelos, PR | 1 |
| Chua, BH; Giger, KE; Kleinhans, BJ; Morgan, HE; Robishaw, JD | 1 |
| Kent, RL; Reibel, DK; Uboh, CE | 1 |
| Bucovaz, ET; Fryer, JE; Macleod, RM; Morrison, JC; Morrison, WC; Rhoades, JL; Sobhy, CM; Tarnowski, SJ; Wakim, JM; Whybrew, WD | 1 |
| Savage, CR; Smith, CM | 1 |
| Arbizo, MV; Iannucci, J; Milner, R; Smith, CM | 1 |
| Komaki, R; Shimizu, S; Tani, Y; Yamada, H | 1 |
| Jackowski, S; Rock, CO | 2 |
| Branca, D; Scutari, G; Siliprandi, N | 1 |
| Dorofeev, BF; Khomich, TI; Moĭseenok, AG; Sheĭbak, VM | 1 |
| Gross, CJ; Henderson, LM; Shibata, K | 1 |
| Floridi, S; Mei, V; Pranzetti, P; Valora, N | 1 |
| Berkich, DA; Neely, JR; Reibel, DK; Wyse, BW | 2 |
| Cronan, JE; Polacco, ML | 1 |
| Cronan, JE; Jackowski, S; Littel, KJ | 1 |
| Berkich, D; Neely, JR; Robishaw, JD | 1 |
| Hansen, RG; Wittwer, C; Wyse, B | 1 |
| Coates, ME; Latymer, EA | 1 |
| Berkich, DA; Neely, JR; Palko, WM; Reibel, DK; Wyse, BW | 1 |
| Hassinen, IE; Voltti, H | 1 |
| Brass, EP | 1 |
| Moiseenok, AG; Rakowska, M; Slyshenkov, VS; Wojtczak, L | 1 |
| Campos, A; Ciges, M; Crespo, PV; Fernández-Cervilla, F | 1 |
| Badr, MZ; Cunningham, ML; Song, WO; Youssef, JA | 1 |
| Hasan, Y; Loftus, EV; Nelson, RA; Phillips, SF; Sandborn, WJ; Shoemaker, JD; Tremaine, WJ | 1 |
| Badr, MZ; Song, WO; Youssef, JA | 1 |
| Moiseenok, AG; Omelyanchik, SN; Slyshenkov, VS; Trebukhina, RV; Wojtczak, L | 1 |
| Hsu, CW; Shiau, SY | 1 |
| Kinghorn, JR; Kurtov, D; Unkles, SE | 1 |
| Shimizu, S | 1 |
| Downs, DM; Frodyma, M; Rubio, A | 1 |
| Blaesse, M; Jung, G; Kupke, T; Schmid, D; Steinbacher, S; Uebele, M | 1 |
| Hattori, M; Ishikawa, H; Sakaki, Y; Shigenobu, S; Watanabe, H | 1 |
| Begley, TP; Kinsland, C; Strauss, E | 1 |
| Richter, H; Unden, G; Vlad, D | 1 |
| Begley, TP; Ge, Y; Kinsland, C; McLafferty, FW; Strauss, E | 1 |
| Culianez-Macia, FA; Hernandez-Acosta, P; Kupke, T; Steinbacher, S | 1 |
| Bacon, JA; Brass, EP; Cramer, CT; Petrella, DK; Sun, EL; Ulrich, RG | 1 |
| Begley, TP; Strauss, E | 2 |
| Miller, SL; Schlesinger, G | 1 |
| Downs, DM; Rubio, A | 1 |
| Badr, M; Davis, A; Morrow, JD; Roberts, LJ; Swift, LL; Youssef, J | 1 |
| Jackowski, S; Park, HW; Rock, CO | 1 |
| Begley, TP; Broskey, JP; Brown, JR; Choudhry, AE; Egolf, RW; Kinsland, C; Ku, TW; Mandichak, TL; Ratnam, K; Seefeld, MA; Zalacain, M | 1 |
| HUGHES, DE; PIERPOINT, WS | 1 |
| HOAGLAND, MB; NOVELLI, GD | 1 |
| BRIGNON, J; DUBOST, S; WOLFF, R | 1 |
| CALVIN, M; HUGHES, AM; KIRK, MR; TOLBERT, BM | 1 |
| DIETRICH, LS; SHAPIRO, DM | 1 |
| BRIGNON, JJ; DUBOST, S; WOLFF, RL | 1 |
| BRIGNON, JJ; DUBOST, S; WOLFF, R | 1 |
| MARCHETTI, M; MORUZZI, G; SANGUINETTI, F; VIVIANI, R | 1 |
| MASSACESI, R; NORDIO, S; SEGNI, G | 1 |
| CAUSI, N; GALFANO, G; ROMANO, A | 1 |
| BROWN, GM; REYNOLDS, JJ | 1 |
| BAKACSI, G; NAGY, ME; SZORADY, I | 1 |
| LANZANI, P; MASCITELLI-CORIANDOLI, E | 1 |
| ALBERTS, AW; MAJERUS, PW; VAGELOS, PR | 1 |
| HIRABAYASHI, M; NOSE, Y | 1 |
| CHANG, SH; WILKEN, DR | 1 |
| CAVALLA, JF | 1 |
| CHEVREMONT, M; FIRKET, H; MOUCHETTE, R | 1 |
| MARCHETTI, M; SECHI, AM; VIVIANI, R | 1 |
| Koteva, KP; Nazi, I; Wright, GD | 1 |
| MASLEY, PM; McRORIE, RA; WILLIAMS, WL | 1 |
| HIGGINS, H; MILLER, JA; PRICE, JM; STRONG, FM | 1 |
| CRAIG, JA; SNELL, EE | 1 |
| Grünewald, J; Marahiel, MA; Sieber, SA | 1 |
| Genschel, U | 1 |
| Leung, LH | 1 |
| Frank, MW; Jackowski, S; Lee, RE; Rock, CO; Virga, KG; Zhang, YM | 1 |
| Hiraoka, M; Yasuda, K | 1 |
| Brand, LA; Strauss, E | 1 |
| Roth-Maier, D; Rychlik, M | 1 |
| Burkart, MD; Worthington, AS | 1 |
| Claiborne, A; Fahey, RC; Jackowski, S; Leonardi, R; Mallett, TC; Newton, GL; Nicely, NI; Paige, C; Parsonage, D | 1 |
| Bain, JR; Chohnan, S; Ilkayeva, OR; Jackowski, S; Lee, RE; Newgard, CB; Rock, CO; Stevens, RD; Virga, KG; Wenner, BR; Zhang, YM | 1 |
| Kirk, K; Lehane, AM; Marchetti, RV; Saliba, KJ; Spry, C; Teng, R; van Schalkwyk, DA | 1 |
| Chhibber, M; Kumar, P; Surolia, A | 1 |
| KAPLAN, NO; LIPMANN, F; NOVELLI, GD | 1 |
| HIRSCH, EG; OLSON, RE | 1 |
| Kirk, K; Saliba, KJ; Spry, C | 1 |
| KAPLAN, NO; OLSON, RE | 1 |
| HEGSTED, DM; LIPMANN, F | 1 |
| Strauss, E; van Wyk, M | 1 |
| Kursula, P; Meriläinen, G; Schmitz, W; Wierenga, RK | 1 |
| Chetnani, B; Das, S; Kumar, P; Surolia, A; Vijayan, M | 1 |
| Saliba, KJ; Spry, C | 2 |
| Horváth, Z; Vécsei, L | 1 |
| Cronan, JE; Thomas, J | 1 |
| LIPMANN, F; NOVELLI, GD | 1 |
| Saliba, KJ; Spry, C; Strauss, E; van Schalkwyk, DA | 1 |
| Basu, SS; Blair, IA; Gelhaus, SL; Mesaros, C | 1 |
| Cezar, GG; Conard, KR; Dix, DJ; Donley, EL; Fontaine, BR; Kleinstreuer, NC; Knudsen, TB; Palmer, JA; Smith, AM; Weir-Hauptman, AM; West, PR | 1 |
| Constantin-Teodosiu, D; Greenhaff, PL; Macdonald, IA; Marimuthu, K; Stephens, FB; Wall, BT | 1 |
| Abraham, LJ; Blangero, J; Kaskow, BJ; Michael Proffit, J; Moses, EK; Proffitt, JM | 1 |
| Bertini, E; Caccia, C; Ciusani, E; Clish, CB; Deik, A; Dusi, S; Garavaglia, B; Leoni, V; Mootha, VK; Nardocci, N; Rimoldi, M; Souza, AL; Strittmatter, L; Tiranti, V; Venco, P; Zibordi, F; Zorzi, G | 1 |
| Escalante-Semerena, JC; Hodge, KM; Stuecker, TN | 1 |
| Burkart, MD; Dahesh, S; Hammons, JC; Meier, JL; Moolman, WJ; Nizet, V; Pelly, SC; Strauss, E; van der Westhuyzen, R | 1 |
| Fukuwatari, T; Nakai, T; Shibata, K | 1 |
| Atomi, H; Hiratake, J; Imanaka, T; Ishibashi, T; Kishimoto, A; Kita, A; Miki, K; Morikita, T; Tomita, H; Watanabe, B; Yokooji, Y | 1 |
| Chohnan, S; Hanada, S; Katoh, H; Tamaki, H; Tokutake, Y | 1 |
| Brunton, JC; Fuller, JR; Kawula, TH; Kijek, TM; LoVullo, ED; Miller, CN; Richardson, AR; Steele, SP; Taft-Benz, SA | 1 |
| Atomi, H; Imanaka, T; Ishibashi, T; Tomita, H; Yokooji, Y | 1 |
| Lee, RE; Lin, Z; Macuamule, C; Saliba, KJ; Spry, C; Strauss, E; Virga, KG | 1 |
| Azumano, I; Fukuwatari, T; Higashiyama, S; Onda, M; Shibata, K; Sugita, C | 1 |
| Fukuwatari, T; Kaneko, M; Shibata, K | 1 |
| Nitto, T; Onodera, K | 1 |
| Chen, D; Hu, Y; Lam, H; Liu, X; Pai, PJ | 1 |
| Chohnan, S; Higashi, K; Kurikawa, K; Murase, M; Ogata, Y | 1 |
| Auclair, K; Awuah, E; Habib, E; Hoegl, A; Ma, E; Vong, K | 1 |
| Abell, C; Blundell, TL; Cunningham, F; Hung, AW; Mageed, SN; McConkey, GA; Silvestre, HL; Wen, S | 1 |
| Gout, I; Jackowski, S; Sibon, OC; Theodoulou, FL | 1 |
| Jansen, P; Schalkwijk, J | 1 |
| Hayflick, SJ | 1 |
| Barnard, L; de Villiers, M; Koekemoer, L; Snoep, JL; Strauss, E | 1 |
| Downs, DM; Ernst, DC | 1 |
| Bartlett, CP; Gowdy, JA; Grant, TD; Kalverda, AP; Monteiro, DCF; Niki, H; Nozaki, S; Patel, V; Pearson, AR; Snell, EH; Thompson, GS; Webb, ME | 1 |
| Frank, M; Jackowski, S; Pate, C; Rock, CO; Zano, SP | 1 |
| Chen, Y; Jiang, S; Li, B; Li, H; Lin, W; Sun, Y; Wang, X; Wei, X; Yuan, J; Zhao, X | 1 |
| Gabriele, S; Gevi, F; Persico, AM; Zolla, L | 1 |
| Barnard, L; de Villiers, M; Macuamule, CJ; Saliba, KJ; Spry, C; Strauss, E; Wells, G | 1 |
| Arnott, ZLP; Monteiro, DCF; Morgan, HE; Niki, H; Nozaki, S; Pearson, AR; Webb, ME | 1 |
| Abramov, AY; Angelova, PR; Arber, C; Bhatia, KP; Duce, JA; Gout, I; Hardy, J; Houlden, H; Mazzacuva, F; Mills, K; Preza, E; Tsuchiya, Y; Wiethoff, S; Wray, S | 1 |
| Beconi, MG; Di Marco, A; Elbaum, D; Harper, S; Lyons, KA; Monteagudo, E; Quinton, MS; Vaino, A | 1 |
| Auclair, K; Barnard, L; Creek, DJ; Hoegl, A; Howieson, VM; Maier, AG; Marquez, R; Saliba, KJ; Sewell, AL; Sexton, AE; Siddiqui, G; Spry, C; Strauss, E; Tjhin, ET | 1 |
| Blank, LM; Czarnotta, E; Ebert, BE | 1 |
| Borsani, G; Finazzi, D; Khatri, D; Monti, E; Trivedi, A; Zizioli, D | 1 |
| Álvarez-Córdoba, M; Armengol, JA; Cotán, D; de la Mata, M; Díaz-Quintana, A; Fernández Khoury, A; Gómez-Navarro, C; Pérez-Pulido, AJ; Pérez-Villegas, EM; Povea-Cabello, S; Salas, JJ; Sánchez-Alcázar, JA; Suárez-Rivero, JM; Talaverón-Rey, M; Villalón-García, I; Villanueva-Paz, M | 1 |
| Auclair, K; Duncan, D | 1 |
| Ben Mamoun, C; Bracher, F; Chiu, JE; Mehta, S; Müller, C; Thekkiniath, J | 1 |
| Dai, P; Guo, X; Jiang, S; Liu, T; Ma, T; Xie, P; Yi, W | 1 |
| Broad, EM; Burke, LM; Harris, RC; Patterson, AK; Ross, MLR; Shaw, G; Spriet, LL; Whitfield, J | 1 |
| Auciello, G; Beconi, M; Bracacel, E; Ciammaichella, A; Cicero, D; Di Marco, A; Elbaum, D; Fezzardi, P; Gonzalez Paz, O; Harper, S; Malancona, S; Monteagudo, E; Rossetti, I; Vecchi, A | 1 |
| Abell, C; Barry, CE; Blundell, TL; Boshoff, HIM; Coyne, AG; Evans, JC; Green, SR; Hess, J; Lynch, SL; Mendes, V; Mizrahi, V; Murugesan, D; Nahiyaan, N; Post, JM; Ray, PC; Rhee, KY; Spry, C; Thompson, S; Wang, Z; Wyatt, PG | 1 |
| Baumgaertel, K; Bonelli, F; Ciammaichella, A; Colaceci, F; di Pasquale, P; Elbaum, D; Liu, K; Monteagudo, E; Orsale, MV; Orsatti, L; Rossetti, I; Vecchi, A | 1 |
| Anand, R; Koekemoer, L; Mostert, KJ; Sharma, N; Sibon, OCM; Staats, R; Strauss, E; van der Zwaag, M | 1 |
| Jeon, Y; Kim, EK; Lim, Y; Yeom, J | 1 |
| de Vries, LE; Kooij, TWA; Krishnan, A; Lunghi, M; Soldati-Favre, D | 1 |
| Kloehn, J; Krishnan, A; Lunghi, M; Soldati-Favre, D; Vadas, O; Varesio, E | 1 |
| Bourgin, M; Kepp, O; Kroemer, G | 1 |
| Asara, JM; Barritt, SA; Bartee, D; Cantley, LC; Clohessy, JG; Cohen, EB; Dibble, CC; DuBois-Coyne, SE; Geck, RC; Hopkins, BD; Lien, EC; Meier, JL; Perry, GE; Toker, A; Yuan, M; Zengeya, TT | 1 |
| Bover, L; Khadka, S; Leonard, P; Muller, F; Vien, L | 1 |
| Chen, C; Chen, S; Han, C; Huang, Z; Jiang, W; Liu, Q; Ma, H; Mei, Q; Pan, W; Zhang, C; Zhang, K; Zhang, W; Zhou, R; Zhou, T; Zhu, S | 1 |
| Asadi, P; Gamberi, C; Milev, MP; Sacher, M; Saint-Dic, D | 1 |
| Kanunnikova, NP; Moiseenok, AG | 1 |
| Galland, F; Miallot, R; Millet, V; Naquet, P | 1 |
| Berchard, P; Bertucci, F; Blay, JY; Dutour, A; Fenouil, R; Finetti, P; Galland, F; Henri, S; Malissen, B; Martin, JC; Miallot, R; Millet, V; Naquet, P; Roger, A; Shintu, L; Sousa Lanza, J; Tardivel, C; Ugolini, S | 1 |
32 review(s) available for pantothenic acid and coenzyme a
| Article | Year |
|---|---|
Cofactors and vitamins in the metabolism of malarial parasites. Factors other than folates.
Topics: Animals; Biotin; Chickens; Coenzyme A; Ducks; Erythrocytes; Folic Acid; Haplorhini; Pantothenic Acid; Plasmodium; Vitamin B Complex | 1977 |
Pantothenic acid in health and disease.
Topics: Acylation; Animals; Coenzyme A; Hormones; Humans; Nutritional Requirements; Pantothenic Acid | 1991 |
Coenzyme A metabolism.
Topics: Acetyl Coenzyme A; Animals; Coenzyme A; Diet; Kinetics; Liver; Myocardium; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Subcellular Fractions; Tissue Distribution | 1985 |
Pantothenic acid and coenzyme A in cellular modification of proteins.
Topics: Coenzyme A; Humans; Pantothenic Acid; Proteins | 1988 |
Biosynthesis of water-soluble vitamins.
Topics: Animals; Candida; Carbon Radioisotopes; Clostridium perfringens; Coenzyme A; Escherichia; Glucose; Glycerol; Kidney; Liver; Mutation; Organophosphorus Compounds; Pantothenic Acid; Propionibacterium; Proteus; Pyridoxine; Pyruvates; Rats; Riboflavin; Saccharomyces cerevisiae; Species Specificity; Streptomyces; Vitamin B 12 | 1974 |
[Coenzyme A. 3. Structural specificity of CoA for phosphotransacetylase].
Topics: Acyltransferases; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Escherichia coli; Kinetics; NADP; Nucleotides; Pantothenic Acid; Phosphoric Acids | 1971 |
Acyl carrier protein.
Topics: Acetates; Acyltransferases; Amino Acid Sequence; Amino Acids; Animals; Apoproteins; Bacteria; Bacterial Proteins; Carrier Proteins; Chemical Phenomena; Chemistry; Coenzyme A; Escherichia coli; Fatty Acid Synthases; Fatty Acids; Hydro-Lyases; Ligases; Oxidoreductases; Pantothenic Acid; Peptides, Cyclic; Phospholipids; Phosphoric Acids; Plants; Protein Binding; Proteins | 1972 |
[Mechanism and regulation of the biosynthesis of fatty acids].
Topics: Amides; Animals; Carbon Isotopes; Chromatography; Coenzyme A; Fatty Acids; Malonates; Models, Chemical; Pantothenic Acid; Peptide Hydrolases | 1967 |
[The kidney and pantothenic acid].
Topics: Animals; Avitaminosis; Birds; Coenzyme A; Dogs; Invertebrates; Kidney; Mammals; Mice; Pantothenic Acid; Rats | 1969 |
[Coenzyme A. 1. Biosynthesis of CoA by rat liver enzymes].
Topics: Alcohols; Animals; Bile Acids and Salts; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Coenzyme A; Cysteine; Cystine; Liver; Pantothenic Acid; Phosphotransferases; Pyrophosphatases; Rats | 1971 |
[Coenzyme A. 2. Chemical synthesis of CoA and its analogs].
Topics: Chemical Phenomena; Chemistry; Coenzyme A; Esters; Pantothenic Acid; Phosphoric Acids; Phosphotransferases | 1971 |
The role of phosphopantetheine in the yeast fatty acid synthetase complex.
Topics: Acyltransferases; Binding Sites; Carrier Proteins; Coenzyme A; Fatty Acid Synthases; Fatty Acids; Malonates; Models, Biological; Models, Structural; Pantothenic Acid; Phosphoric Acids; Protein Binding; Sulfhydryl Compounds; Yeasts | 1970 |
Tricarboxylic acid activator-induced changes at the active site of acetyl-CoA carboxylase.
Topics: Adipose Tissue; Allosteric Regulation; Animals; Bicarbonates; Binding Sites; Biotin; Carboxy-Lyases; Cattle; Chemical Phenomena; Chemistry; Chickens; Citrates; Coenzyme A; Enzyme Activation; Ligases; Liver; Macromolecular Substances; Malonates; Models, Biological; Ovalbumin; Pantothenic Acid; Phosphoric Acids; Protein Conformation; Tricarboxylic Acids | 1970 |
[Pantothenic acid].
Topics: Animals; Coenzyme A; Humans; Pantothenic Acid | 1999 |
The biosynthesis of coenzyme A in bacteria.
Topics: Coenzyme A; Decarboxylation; Escherichia coli; Humans; Oxidation-Reduction; Pantothenic Acid; Saccharomyces cerevisiae | 2001 |
Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon.
Topics: Animals; Anti-Anxiety Agents; Carnitine; Cell Hypoxia; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clinical Trials, Phase I as Topic; Coenzyme A; Drug Evaluation, Preclinical; Hepatocytes; Humans; Mitochondria; Oxadiazoles; Pantothenic Acid; Quinoxalines; Rabbits; Reye Syndrome; Species Specificity | 2001 |
BIOGENESIS OF THE WATER-SOLUBLE VITAMINS.
Topics: Alanine; Benzimidazoles; Biotin; Coenzyme A; Flavins; Folic Acid; Hydroxocobalamin; Metabolism; NAD; Niacin; Nicotinic Acids; Nucleosides; Oxidoreductases; Pantothenic Acid; Phosphotransferases; Pterins; Pyridoxine; Research; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamin B 12; Vitamins | 1963 |
[Pantothenic acid].
Topics: Biological Assay; Biomarkers; Chromatography, High Pressure Liquid; Coenzyme A; Foot; gamma-Aminobutyric Acid; Humans; Pantothenic Acid; Reference Values; Sensation Disorders; Specimen Handling; Syndrome | 2004 |
Coenzyme A biosynthesis: an antimicrobial drug target.
Topics: Acyl Carrier Protein; Animals; Anti-Infective Agents; Bacterial Physiological Phenomena; Coenzyme A; Drug Design; Enzyme Inhibitors; Fungi; Humans; Malaria; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Plasmodium | 2008 |
Current medical aspects of pantethine.
Topics: Acetylcholine; Animals; Antioxidants; Atherosclerosis; Blood Platelets; Cataract; Central Nervous System; Coenzyme A; Cystine; Cystinosis; Dietary Carbohydrates; Fatty Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Oxidation-Reduction; Pantetheine; Pantothenic Acid; Pyruvates | 2009 |
Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.
Topics: Amino Acid Sequence; Animals; Antimalarials; Coenzyme A; Drug Discovery; Erythrocytes; Humans; Malaria; Molecular Sequence Data; Pantothenic Acid; Plasmodium; Protein Conformation | 2010 |
Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cardiovascular Diseases; Cell Membrane; Coenzyme A; GPI-Linked Proteins; Humans; Inflammation; Mice; Molecular Sequence Data; Pantetheine; Pantothenic Acid | 2012 |
CoA biosynthesis in archaea.
Topics: Biological Evolution; Coenzyme A; Pantothenic Acid; Phosphotransferases; Thermococcus | 2013 |
Linkage between coenzyme a metabolism and inflammation: roles of pantetheinase.
Topics: Amidohydrolases; Animals; Cell Adhesion Molecules; Coenzyme A; Cysteamine; Disease Progression; GPI-Linked Proteins; Humans; Hydrolysis; Inflammation; Macrophage-1 Antigen; Multigene Family; Neutrophils; Oxidative Stress; Pantetheine; Pantothenic Acid; Proteolysis | 2013 |
Coenzyme A and its derivatives: renaissance of a textbook classic.
Topics: Acetylation; Animals; Coenzyme A; Humans; Neurodegenerative Diseases; Pantothenic Acid | 2014 |
Chemical biology tools to study pantetheinases of the vanin family.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Coenzyme A; GPI-Linked Proteins; Pantothenic Acid; Plasmodium falciparum; Staphylococcus aureus | 2014 |
Defective pantothenate metabolism and neurodegeneration.
Topics: Animals; Coenzyme A; Humans; Neurodegenerative Diseases; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor) | 2014 |
Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides.
Topics: Amidohydrolases; Animals; Antimalarials; Coenzyme A; GPI-Linked Proteins; Humans; Malaria; Pantothenic Acid; Plasmodium falciparum | 2014 |
The coenzyme A biosynthetic pathway: A new tool for prodrug bioactivation.
Topics: Animals; Anti-Infective Agents; Coenzyme A; Enzyme Inhibitors; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Proof of Concept Study; Substrate Specificity | 2019 |
Pantothenate and CoA biosynthesis in Apicomplexa and their promise as antiparasitic drug targets.
Topics: Animals; Antiparasitic Agents; Apicomplexa; Coenzyme A; Humans; Pantothenic Acid; Protozoan Infections | 2021 |
Brain CoA and Acetyl CoA Metabolism in Mechanisms of Neurodegeneration.
Topics: Acetyl Coenzyme A; Brain; Coenzyme A; Humans; Pantothenic Acid; Proteins | 2023 |
The vitamin B5/coenzyme A axis: A target for immunomodulation?
Topics: Coenzyme A; Humans; Immunomodulation; Inflammation; Pantothenic Acid | 2023 |
2 trial(s) available for pantothenic acid and coenzyme a
| Article | Year |
|---|---|
Dexpanthenol enemas in ulcerative colitis: a pilot study.
Topics: Administration, Topical; Adult; Coenzyme A; Colitis, Ulcerative; Dicarboxylic Acids; Enema; Fatty Acids, Volatile; Female; Humans; Male; Middle Aged; Pantothenic Acid; Pilot Projects | 1997 |
Acute pantothenic acid and cysteine supplementation does not affect muscle coenzyme A content, fuel selection, or exercise performance in healthy humans.
Topics: Biomarkers; Biopsy; Coenzyme A; Cysteine; Exercise Test; Exercise Tolerance; Glycogen; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Pantothenic Acid; Young Adult | 2012 |
256 other study(ies) available for pantothenic acid and coenzyme a
| Article | Year |
|---|---|
The synthesis of acetylcholine from acetyl-CoA, acetyl-dephospho-CoA and acetylpantetheine phosphate by choline acetyltransferase.
Topics: Acetyl Coenzyme A; Acetylcholine; Acetyltransferases; Choline O-Acetyltransferase; Citrate (si)-Synthase; Coenzyme A; Hydrogen-Ion Concentration; Kinetics; Pantothenic Acid; Sodium | 1977 |
Coenzyme A requirement of malaria parasites: enzymes of coenzyme A biosynthesis in normal duck erythrocytes and erythrocytes infected with Plasmodium lophurae.
Topics: Adenosine Triphosphate; Animals; Carboxy-Lyases; Coenzyme A; Cysteine; Erythrocytes; Nucleotidyltransferases; Pantetheine; Pantothenic Acid; Peptide Synthases; Phosphotransferases; Plasmodium | 1975 |
Biosynthesis of sphingomyelin in rat liver endoplasmic reticulum.
Topics: Animals; Coenzyme A; Cyclic AMP; Endoplasmic Reticulum; Microsomes, Liver; Oxidation-Reduction; Pantothenic Acid; Phosphotransferases; Rats; Ribonucleotides; Sphingomyelins; Structure-Activity Relationship | 1976 |
Regulation of phosphatidylcholine synthesis in rat liver endoplasmic reticulum.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Coenzyme A; Cystamine; Cysteamine; Diacylglycerol Cholinephosphotransferase; Endoplasmic Reticulum; Liver; Manganese; Nucleotides; Pantetheine; Pantothenic Acid; Phosphatidylcholines; Rats | 1976 |
Isolation of temperature-sensitive pantothenate kinase mutants of Salmonella typhimurium and mapping of the coaA gene.
Topics: Cell-Free System; Chromosome Mapping; Coenzyme A; Genes; Mutation; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Salmonella typhimurium; Temperature; Transduction, Genetic | 1979 |
Mitochondrial biosynthesis of coenzyme A.
Topics: Animals; Carboxy-Lyases; Coenzyme A; Kinetics; Ligases; Male; Mitochondria, Liver; Nucleotidyltransferases; Pantetheine; Pantothenic Acid; Phosphotransferases; Rats | 1979 |
Synthesis of coenzyme A and its biosynthetic intermediates by microbial processes.
Topics: Brevibacterium; Coenzyme A; Kinetics; Methods; Pantothenic Acid | 1979 |
Increased biosynthesis of CoA in the liver of rats treated with clofibrate.
Topics: Acyl Coenzyme A; Animals; Clofibrate; Coenzyme A; Liver; Male; Pantothenic Acid; Rats; Subcellular Fractions | 1979 |
Clofibrate-induced increase in coenzyme A concentration in rat tissues.
Topics: Animals; Chromatography, DEAE-Cellulose; Clofibrate; Coenzyme A; Kidney; Kinetics; Liver; Male; Muscles; Myocardium; Pantothenic Acid; Rats; Tissue Distribution | 1979 |
The relationship between metabolic state and total CoA content of rat liver and heart.
Topics: Acyl Coenzyme A; Animals; Coenzyme A; Diabetes Mellitus, Experimental; Fasting; Feeding Behavior; Liver; Male; Mitochondria, Liver; Myocardium; Pantothenic Acid; Rats | 1978 |
The effect of metabolic state on incorportion of [14C] pantothenate into CoA in rat liver and heart.
Topics: Animals; Coenzyme A; Cysteine; Dietary Carbohydrates; Fasting; Glucose; Liver; Male; Mitochondria, Liver; Myocardium; Pantothenic Acid; Rats | 1978 |
Inhibition of rat liver CDPethanolamine: 1,2-diacylglycerol ethanolamine-phosphotransferase activity by ATP and pantothenic acid derivatives.
Topics: Adenosine Triphosphate; Animals; Coenzyme A; Diglycerides; Ethanolamines; Male; Microsomes, Liver; Pantothenic Acid; Phosphatidylethanolamines; Phosphotransferases; Rats | 1977 |
Pantothenic acid, coenzyme A, and human chronic ulcerative and granulomatous colitis.
Topics: Adult; Chronic Disease; Coenzyme A; Colitis; Colitis, Ulcerative; Colon; Erythrocytes; Female; Granuloma; Humans; Intestinal Mucosa; Male; Pantothenic Acid | 1976 |
Synergistic growth promoting action of L-cysteine and nitrogen upon Hymenolepis diminuta cysticercoids in vitro.
Topics: Animals; Ascorbic Acid; Cestoda; Coenzyme A; Cysteine; Drug Synergism; Hymenolepis; Nitrogen; Pantothenic Acid | 1976 |
Coezyme A requirement of malaria parasites: effects of coenzyme A precursors on extracellular development in vitro of Plasmodium lophurae.
Topics: Animals; Coenzyme A; Ducks; Enzyme Precursors; Erythrocytes; Pantothenic Acid; Plasmodium | 1975 |
13C NMR or coenzyme A and its constituent moieties.
Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Coenzyme A; Cystamine; Cysteamine; Deuterium; Disulfides; Lactones; Magnetic Resonance Spectroscopy; Mercaptoethylamines; Pantetheine; Pantothenic Acid; Protein Conformation | 1975 |
Amelioration of adverse effects of valproic acid on ketogenesis and liver coenzyme A metabolism by cotreatment with pantothenate and carnitine in developing mice: possible clinical significance.
Topics: Animals; Animals, Suckling; Carnitine; Coenzyme A; Cysteine; Ketone Bodies; Liver; Mice; Pantothenic Acid; Valproic Acid | 1992 |
Evidence for an in vivo modification of mitochondrial proteins by coenzyme A.
Topics: Acetyl-CoA C-Acetyltransferase; Acetyl-CoA C-Acyltransferase; Animals; Carbon Radioisotopes; Cell Fractionation; Coenzyme A; Male; Microsomes; Mitochondria; Pantothenic Acid; Proteins; Rats; Rats, Inbred Strains; Submitochondrial Particles | 1991 |
Metabolism of pantothenic acid in hearts of diabetic rats.
Topics: Animals; Coenzyme A; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Myocardium; Pantothenic Acid; Rats; Rats, Inbred Strains | 1989 |
Enzymes for liberation of pantothenic acid in blood: use of plasma pantetheinase.
Topics: Alkaline Phosphatase; Amidohydrolases; Animals; Chickens; Coenzyme A; Columbidae; GPI-Linked Proteins; Humans; Hydrolysis; Kidney; Pantothenic Acid; Species Specificity; Swine; Temperature | 1989 |
Isolation and characterization of temperature-sensitive pantothenate kinase (coaA) mutants of Escherichia coli.
Topics: beta-Alanine; Coenzyme A; Escherichia coli; Genes; Genes, Bacterial; Mutation; Pantothenic Acid; Phenotype; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Temperature; Transduction, Genetic | 1987 |
The effect of tumour growth on liver pantothenate, CoA, and fatty acid synthetase activity in the mouse.
Topics: Acetyl Coenzyme A; Animals; Coenzyme A; Fatty Acid Synthases; Fibrosarcoma; Liver; Lymphoma; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Sarcoma 180 | 1988 |
Isolation and characterization of Escherichia coli pantothenate permease (panF) mutants.
Topics: beta-Alanine; Chromosome Mapping; Coenzyme A; DNA Transposable Elements; Escherichia coli; Membrane Transport Proteins; Mutation; Pantothenic Acid; Phenotype | 1985 |
Possible role of acetyl-CoA in the inhibition of CoA biosynthesis by ethanol in rats.
Topics: Acetaldehyde; Acetates; Acetyl Coenzyme A; Animals; Cells, Cultured; Coenzyme A; Cyanamide; Ditiocarb; Ethanol; Liver; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Rats | 1987 |
Pantothenic acid transport and metabolism in the central nervous system.
Topics: Animals; Biological Transport, Active; Brain; Choroid Plexus; Chromatography, High Pressure Liquid; Coenzyme A; Injections, Intravenous; Injections, Intraventricular; Mannitol; Pantothenic Acid; Rabbits; Time Factors | 1986 |
Activation and inhibition of yeast aldehyde dehydrogenase activity by pantethine and its metabolites.
Topics: Acetyl Coenzyme A; Aldehyde Dehydrogenase; Coenzyme A; Cysteamine; Enzyme Activation; Pantetheine; Pantothenic Acid; Saccharomyces cerevisiae; Sulfhydryl Compounds; Taurine | 1986 |
Effects of acute and chronic ethanol ingestion on pantothenate and CoA status of rats.
Topics: Animals; Coenzyme A; Dose-Response Relationship, Drug; Ethanol; Female; Heart; Liver; Male; Myocardium; Pantothenic Acid; Rats; Rats, Inbred Strains | 1987 |
[Decrease in the concentration of leukocyte acetylation coenzyme associated with vitamin precursor deficiency in patients with alcoholic delirium].
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Coenzyme A; Combined Modality Therapy; Humans; Leukocytes; Middle Aged; Pantothenic Acid; Psychoses, Alcoholic | 1987 |
Hepatic CoA, S-acyl-CoA, biosynthetic precursors of the coenzyme and pantothenate-protein complexes in dietary pantothenic acid deficiency.
Topics: Acyl Coenzyme A; Animals; Body Weight; Coenzyme A; Liver; Male; Pantetheine; Pantothenic Acid; Proteins; Rats | 1987 |
The effect of pantothenate deficiency in mice on their metabolic response to fast and exercise.
Topics: Animals; Coenzyme A; Fasting; Glucose; Ketone Bodies; Liver Glycogen; Mice; Mice, Inbred C57BL; Muscles; Pantothenic Acid; Physical Exertion; Time Factors | 1987 |
Pantothenate transport in Escherichia coli.
Topics: Biological Transport; Coenzyme A; Escherichia coli; Osmotic Pressure; Pantothenic Acid; Sodium | 1985 |
Coenzyme A biosynthesis: steric course of 4'-phosphopantothenoyl-L-cysteine decarboxylase.
Topics: Animals; Carboxy-Lyases; Chromatography, Gas; Coenzyme A; Cysteine; Indicators and Reagents; Liver; Magnetic Resonance Spectroscopy; Multienzyme Complexes; Pantothenic Acid; Peptide Synthases; Rats; Stereoisomerism | 1985 |
Mammalian fatty acid synthetase. I. Purification and properties of human liver complex.
Topics: Adolescent; Binding Sites; Carbon Radioisotopes; Child; Chromatography, DEAE-Cellulose; Chromatography, Gel; Coenzyme A; Electrophoresis, Disc; Fatty Acid Synthases; Humans; Liver; Male; Molecular Weight; NADP; Oxidation-Reduction; Palmitic Acids; Pantothenic Acid; Protein Binding; Spectrophotometry, Ultraviolet; Tritium; Ultracentrifugation | 1974 |
Inhibition of glucose 6-phosphate dehydrogenase by palmitoyl coenzyme A.
Topics: Alkylation; Animals; Candida; Carbon Radioisotopes; Carnitine; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Coenzyme A; Dextrins; Fatty Acids; Glucosephosphate Dehydrogenase; Macromolecular Substances; Molecular Weight; Mycobacterium; NADP; Palmitic Acids; Pantothenic Acid; Polysaccharides, Bacterial; Protein Binding; Saccharomyces cerevisiae; Serum Albumin, Bovine; Species Specificity; Structure-Activity Relationship | 1974 |
[Role of pantothenic acid in rats subjected to a high fat and low protein diet].
Topics: Animals; Body Weight; Coenzyme A; Dietary Fats; Dietary Proteins; Growth; Lipids; Liver; Male; Pantothenic Acid; Proteins; Rats | 1968 |
[Influence of magnesium on enzymatic synthesis of coenzyme A].
Topics: Adenosine Triphosphate; Animals; Coenzyme A; Columbidae; Liver; Liver Extracts; Magnesium; Pantothenic Acid; Time Factors | 1970 |
Effect of thyroxine in rats deficient in pantothenic acid.
Topics: Animals; Basal Metabolism; Body Weight; Coenzyme A; Male; Pantothenic Acid; Rats; Thyroxine; Vitamin B Deficiency | 1971 |
[Influence of biological compounds with a sulfhydryl group on the intestinal absorption of glucose].
Topics: Animals; Biological Transport, Active; Coenzyme A; Cysteine; Glucose; Glutathione; Intestinal Absorption; Male; Pantothenic Acid; Rats | 1971 |
Oxy-coenzyme A: a competitive inhibitor of coenzyme A in the phosphotransacetylase reaction.
Topics: Acyltransferases; Antimetabolites; Chromatography, Paper; Coenzyme A; Enzymes; In Vitro Techniques; Kinetics; Pantothenic Acid; Phosphoric Monoester Hydrolases; Spectrophotometry; Ultraviolet Rays; Venoms | 1965 |
Regulation of pyruvate carboxylase by coenzyme A and acyl coenzyme A thio esters.
Topics: Bicarbonates; Chromatography; Coenzyme A; Cyclic AMP; Esters; Hydrogen-Ion Concentration; Kinetics; Ligases; Pantothenic Acid; Pyruvates; Saccharomyces; Sulfur | 1968 |
Purification and properties of D-pantothenate kinase from rat liver.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Coenzyme A; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Liver; Magnesium; Male; Pantothenic Acid; Phosphoric Acids; Phosphoric Monoester Hydrolases; Phosphotransferases; Protamines; Rats; Structure-Activity Relationship; Sucrose | 1972 |
Control of pantothenate accumulation in Agrobacterium tumefaciens.
Topics: Alanine; Aspartic Acid; Biotin; Carbon Isotopes; Citric Acid Cycle; Coenzyme A; Culture Media; Fatty Acids; Fumarates; Glutamates; Glycolysis; Ketoglutaric Acids; Malates; Methionine; Mutation; Pantothenic Acid; Perchlorates; Rhizobium; Solvents; Stimulation, Chemical; Succinates | 1973 |
[Experimental pantothenic acid deficiency in the rat].
Topics: Acetylation; Adrenal Cortex Hormones; Animals; Cholesterol; Chromatography; Coenzyme A; Diet; Feces; Female; Glycerol; Hemoglobins; Leucyl Aminopeptidase; Liver; Neomycin; Oxidation-Reduction; Pantothenic Acid; Rats; Sulfanilamides; Sulfonamides; Triglycerides; Vitamin B Deficiency | 1974 |
On the mechanism and control of the malonyl-CoA-dependent chain elongation of fatty acids. The malonyl-transfer reaction.
Topics: Acyltransferases; Animals; Binding, Competitive; Coenzyme A; Ethylmaleimide; Fatty Acid Synthases; Iodoacetates; Kinetics; Malonates; Microsomes, Liver; Pantothenic Acid; Rats | 1974 |
Adaptive synthesis of rat liver fatty acid synthetase: evidence for in vitro formation of active enzyme from inactive protein precursors and 4'-phosphopantetheine.
Topics: Animals; Carbon Radioisotopes; Coenzyme A; Dietary Fats; Enzyme Activation; Fatty Acid Synthases; Liver; Male; Organophosphorus Compounds; Pantetheine; Pantothenic Acid; Rats; Starvation; Sulfhydryl Compounds | 1974 |
Acyl carrier protein in mycoplasmas.
Topics: Acetates; Acholeplasma laidlawii; Acylation; Alanine; Carbon Isotopes; Carrier Proteins; Chromatography; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fatty Acids; Molecular Weight; Mycoplasma; Mycoplasma mycoides; Pantothenic Acid; Protein Precursors; Species Specificity; Temperature | 1973 |
Bibliography of paper and thin-layer chromatography 1966-1969. Vitamins.
Topics: Ascorbic Acid; Bibliographies as Topic; Biotin; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Coenzyme A; Ergocalciferols; Fats; Flavins; Folic Acid; Growth Substances; Nicotinic Acids; Pantothenic Acid; Pteridines; Riboflavin; Solubility; Thiamine; Vitamin B 12; Vitamin E; Vitamin K; Vitamins; Water | 1972 |
Pantothenate uptake in Escherichia coli K-12.
Topics: Carbon Radioisotopes; Chloramphenicol; Coenzyme A; Depression, Chemical; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Pantothenic Acid; Phosphorus; Sulfhydryl Reagents; Temperature; Uncoupling Agents | 1973 |
The isolation of acyl carrier protein from the pigeon liver fatty acid synthetase complex1 II.
Topics: Acetyl Coenzyme A; Animals; Bacterial Proteins; Binding Sites; Carbon Radioisotopes; Carrier Proteins; Chromatography, Gel; Coenzyme A; Columbidae; Dithiothreitol; Electrophoresis, Paper; Escherichia coli; Fatty Acid Synthases; Liver; Malonates; Molecular Weight; Pantothenic Acid; Protein Binding; Proteins; Species Specificity; Sulfhydryl Compounds; Ultracentrifugation; Ultrafiltration | 1974 |
[Acetyl-phosphopantetheine and acetyl-CoA as action groups of citrate lyase].
Topics: Acetates; Binding Sites; Chemical Phenomena; Chemistry; Citrates; Coenzyme A; Klebsiella; Oxaloacetates; Oxo-Acid-Lyases; Pantothenic Acid; Serine; Structure-Activity Relationship | 1972 |
Acyl carrier protein. 28. Chemical synthesis and characterization of a protein with acyl carrier protein activity.
Topics: Amino Acid Sequence; Animals; Antigen-Antibody Reactions; Apoproteins; Bromides; Butanols; Carbon Isotopes; Carrier Proteins; Catalysis; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Coenzyme A; Electrophoresis, Disc; Fatty Acids; Fluoroacetates; Formates; Hydrofluoric Acid; Hydrogenation; Malonates; Organophosphorus Compounds; Pantothenic Acid; Polystyrenes; Rabbits; Sulfhydryl Compounds; Tritium | 1972 |
The substrate specificity of pantethinase.
Topics: Amidohydrolases; Animals; Chemical Phenomena; Chemistry; Coenzyme A; Disulfides; Enzyme Activation; Horses; Kidney; Pantothenic Acid | 1973 |
Fatty acid synthetase of mammalian brain, liver and adipose tissue. Regulation by prosthetic group turnover.
Topics: Adipose Tissue; Animals; Binding Sites; Brain; Carbon Radioisotopes; Carrier Proteins; Chromatography; Chromatography, DEAE-Cellulose; Coenzyme A; Electrophoresis, Disc; Fatty Acid Synthases; Kinetics; Liver; Pantothenic Acid; Polysaccharides; Precipitin Tests; Protein Binding; Rats; Starvation; Time Factors; Tritium | 1973 |
Choline acetyltransferase. Evidence for an acetyl-enzyme reaction intermediate.
Topics: Acetyl Coenzyme A; Acetylcholine; Acetyltransferases; Animals; Binding Sites; Brain; Carbon Isotopes; Carnitine; Catalysis; Cattle; Choline; Chromatography, Gel; Coenzyme A; Cysteine; Drug Stability; Esters; Guanidines; Hydrogen-Ion Concentration; Organophosphorus Compounds; Pantothenic Acid; Sulfhydryl Compounds; Sulfides; Trichloroacetic Acid; Tritium | 1973 |
Production of coenzyme A by Sarcina lutea.
Topics: Adenine; Bacteria; Carbohydrate Metabolism; Charcoal; Chromatography, DEAE-Cellulose; Chromatography, Gel; Coenzyme A; Cysteine; Fermentation; Fungi; Glucose; Magnesium; Nitrogen; Oxygen; Pantothenic Acid; Phosphates; Sarcina; Species Specificity; Temperature; Time Factors | 1974 |
Coenzyme A.
Topics: Age Factors; Aging; Aorta; Arteries; Arteriosclerosis; Biological Assay; Coenzyme A; Humans; Lactobacillus; Pantothenic Acid; Pulmonary Artery; Veins; Vena Cava, Inferior | 1974 |
Separation of the half-molecular weight nonidentical subunits of pigeon liver fatty acid synthetase by affinity chromatography.
Topics: Acyltransferases; Alcohol Oxidoreductases; Aminocaproates; Animals; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Affinity; Coenzyme A; Columbidae; Fatty Acid Synthases; Keto Acids; Liver; Macromolecular Substances; Molecular Weight; Organophosphorus Compounds; Oxidoreductases; Pantothenic Acid | 1974 |
Acyl carrier protein. X. Acyl carrier protein synthetase.
Topics: Chromatography, Gel; Coenzyme A; Escherichia coli; Genetics, Microbial; Hydrogen-Ion Concentration; Kinetics; Ligases; Magnesium; Manganese; Pantothenic Acid; Spectrophotometry; Tritium | 1968 |
The antagonistic action of homopantothenic acid against pantothenic acid.
Topics: Aminobutyrates; Animals; Bacteria; Chickens; Coenzyme A; Culture Media; Depression, Chemical; Escherichia coli; Growth; Lactobacillus; Leuconostoc; Liver; Male; Mice; Pantothenic Acid; Vitamins | 1969 |
Acyl carrier protein. XI. The specificity of acyl carrier protein synthetase.
Topics: Bacterial Proteins; Bicarbonates; Binding Sites; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Coenzyme A; Escherichia coli; Fatty Acids; Fluorides; Kinetics; Ligases; Optical Rotatory Dispersion; Pantothenic Acid; Peptides; Proteins; Tritium | 1969 |
Acyl carrier protein. XII. Synthesis and turnover of the prosthetic group of acyl carrier protein in vivo.
Topics: Bacterial Proteins; Biological Transport, Active; Carbon Isotopes; Coenzyme A; Computers; Culture Media; Escherichia coli; Kinetics; Mathematics; Methods; Models, Chemical; Mutation; Pantothenic Acid; Phosphoric Acids; Protein Binding; Time Factors; Tritium | 1969 |
Effect of adenine nucleotide moiety of coenzyme A on phosphotransacetylase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Amides; Binding Sites; Clostridium; Coenzyme A; Escherichia coli; Kinetics; Pantothenic Acid; Sulfhydryl Compounds | 1970 |
Structural specificity of coenzyme A for phosphotransacetylase.
Topics: Acyltransferases; Adenine Nucleotides; Amides; Binding Sites; Chemical Phenomena; Chemistry; Clostridium; Coenzyme A; Cysteamine; Escherichia coli; Hydroxybutyrates; Kinetics; Pantothenic Acid; Phosphates; Propionates | 1970 |
Attempts to map a process evolution of peptide biosynthesis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Anti-Bacterial Agents; Bacillus; Bacteria; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Coenzyme A; Escherichia coli; Fatty Acids; Molecular Weight; Pantothenic Acid; Peptide Biosynthesis; Peptides, Cyclic; Polymers; Ribosomes; Sulfur; Tritium; Tyrothricin | 1971 |
Pantothenate and coenzyme A in bacterial growth.
Topics: Cell Wall; Coenzyme A; Enterococcus faecalis; Hexosamines; Oleic Acids; Palmitic Acids; Pantothenic Acid; Phospholipids; Surface-Active Agents | 1966 |
Relations between coenzyme A and presumptive acyl carrier protein in different conditions of streptococcal growth.
Topics: Bacterial Proteins; Carbon Isotopes; Coenzyme A; Cystine; Enterococcus faecalis; Pantothenic Acid | 1969 |
[Antagonism between thiopanic and pantothenic acids].
Topics: Animals; Coenzyme A; Drug Antagonism; Drug Synergism; Female; Growth; Hydroxybutyrates; Liver; Liver Glycogen; Male; Pantothenic Acid; Rats; Taurine; Time Factors | 1972 |
Studies on the distribution of pantothenic acid, coenzyme A and their intermediates in rat liver. I. The isolation and the identification of pantothenic acid, 4'-phosphopantetheine and coenzyme A by using column and paper chromatography.
Topics: Animals; Avitaminosis; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Paper; Coenzyme A; Injections, Intraperitoneal; Liver; Male; Pantothenic Acid; Rats; Rats, Inbred Strains | 1972 |
The effect of fasting on synthesis and 4'-phosphopantetheine exchange in rat liver fatty acid synthetase.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, DEAE-Cellulose; Coenzyme A; Diet; Fasting; Fatty Acid Synthases; Half-Life; In Vitro Techniques; Kinetics; Liver; Pantothenic Acid; Phosphoric Acids; Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors; Tritium | 1972 |
Feedback inhibition of pantothenate kinase by coenzyme A and possible role of the enzyme for the regulation of cellular coenzyme A level.
Topics: Animals; Coenzyme A; Feedback; In Vitro Techniques; Kidney; Nucleotides; Pantothenic Acid; Phosphotransferases; Rats | 1972 |
A new process for the production of coenzyme A and its intermediates with a microorganism.
Topics: Adenosine Monophosphate; Amides; Brevibacterium; Chromatography; Chromatography, Ion Exchange; Coenzyme A; Culture Media; Cysteine; Hydroxybutyrates; Methods; Pantothenic Acid; Phosphoric Acids | 1972 |
[The physiologic action of pantothenic acid].
Topics: Adrenal Glands; Animals; Carbohydrate Metabolism; Coenzyme A; Deficiency Diseases; Female; Gonads; Infertility, Female; Lipid Metabolism; Ovulation; Pantothenic Acid; Rats; Tachycardia | 1971 |
Incorporation of C14-pantothenate into the fatty acid synthetase complex of growing baker's yeast.
Topics: Chromatography; Coenzyme A; Fatty Acids; Ligases; Pantothenic Acid; Saccharomyces | 1966 |
Biochemistry of the development of duck embryo. 3. Pantothenic acid, coenzyme A, and nicotinic acid in the developing liver.
Topics: Animals; Coenzyme A; Ducks; Embryonic and Fetal Development; Liver; Nicotinic Acids; Pantothenic Acid | 1968 |
Kipid metabolism in the rats with fatty liver caused by low protein diet and effects of the oral administration of L-methionine, L-cysteine, pantethine and calcium pantothenate upon it.
Topics: Animals; Body Weight; Calcium; Cholesterol; Chromatography, Gas; Coenzyme A; Cysteine; Dietary Fats; Fatty Acids; Fatty Liver; Lipid Metabolism; Lipids; Liver; Male; Methionine; Organ Size; Pantothenic Acid; Phospholipids; Rats; Time Factors; Triglycerides | 1969 |
The role of cysteine desulphhydrase and cysteine synthase in the evolution of hydrogen sulphide in pantothenic acid deficient yeast.
Topics: Adenosine Triphosphate; Chemical Precipitation; Chlorides; Chromatography, DEAE-Cellulose; Chromatography, Gel; Coenzyme A; Cysteine; Hydro-Lyases; Hydrogen; Hydrogen-Ion Concentration; Hydroxylamines; Lyases; Mercury; Methionine; Pantothenic Acid; Quaternary Ammonium Compounds; Saccharomyces; Sulfates; Sulfides; Ultracentrifugation | 1969 |
Acyl carrier protein. 8. Studies of acyl carrier protein and coenzyme A in Escherichia coli pantothenate or betaalanine auxotrophs.
Topics: Alanine; Bacterial Proteins; Chromatography; Coenzyme A; Escherichia coli; Mutation; Pantothenic Acid | 1966 |
[Effects of Pantosin on radiation therapy].
Topics: Coenzyme A; Female; Glutathione; Humans; Liver Diseases; Liver Function Tests; Male; Neoplasms; Pantothenic Acid; Radiation Injuries; Radiation-Protective Agents; Radiotherapy | 1969 |
[Age peculiarities in acetyl-coenzyme A biosynthesis in organs and tissues of albino rats].
Topics: Adenosine Triphosphate; Age Factors; Animals; Brain; Coenzyme A; Cysteine; Hydrocortisone; Intestine, Small; Kidney; Liver; Myocardium; Nicotinic Acids; Pantothenic Acid; Pyruvates; Rats; Stimulation, Chemical; Thiamine; Time Factors | 1969 |
4'-phosphopantetheine, a cofactor bound to guanosine triphosphate-dependent acyl coenzyme A synthetase.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Coenzymes; Guanine Nucleotides; Ligases; Mitochondria, Liver; Molecular Weight; Pantothenic Acid; Phosphates; Rats; Spectrophotometry; Sulfhydryl Compounds | 1970 |
Metabolic vitamin B complex deficiency due to the administration of glucocorticoid.
Topics: Adolescent; Adrenalectomy; Age Factors; Animals; Child; Child, Preschool; Coenzyme A; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glucocorticoids; Humans; Intestinal Mucosa; Kidney; Liver; Male; Pantothenic Acid; Prednisolone; Rats; Riboflavin; Thiamine; Vitamin B Complex; Vitamin B Deficiency | 1970 |
Fatty acyl transferase. Characterization of the enzyme as part of the yeast fatty acid synthetase complex by the use of radioactively labeled coenzyme A.
Topics: Acetates; Acyltransferases; Binding Sites; Butyrates; Carbon Isotopes; Coenzyme A; Ethylmaleimide; Fatty Acids; Hydroxybutyrates; Iodoacetates; Kinetics; Malonates; Palmitic Acids; Pantothenic Acid; Propionates; Saccharomyces; Spectrum Analysis; Sulfhydryl Compounds; Ultraviolet Rays | 1970 |
[Biosynthesis of acylation coenzyme from pantothenate derivatives in the white rat organism].
Topics: Adenosine Triphosphate; Animals; Brain; Coenzyme A; Cysteine; Enzyme Precursors; Hydrocortisone; Intestine, Small; Kidney; Liver; Male; Myocardium; Nicotinic Acids; Pantothenic Acid; Pyruvates; Rats; Thiamine | 1970 |
[Study of interrelations between thiamine, pantothenic and para-aminobenzoic acids].
Topics: Aminobenzoates; Animals; Brain; Coenzyme A; Isomerases; Kidney; Liver; Myocardium; Oxidoreductases; Pantothenic Acid; Pyruvates; Rats; Thiamine | 1970 |
Inhibition of glutathione peroxidase by coenzyme A.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amides; Animals; Coenzyme A; Erythrocytes; Ethylmaleimide; Glutathione; Hydroxybutyrates; Kinetics; Nucleotides; Pantothenic Acid; Peroxidases; Peroxides; Sulfhydryl Compounds; Swine | 1970 |
Protein turnover and 4'-phosphopantetheine exchange in rat liver fatty acid synthetase.
Topics: Amides; Animals; Arginine; Carbon Isotopes; Coenzyme A; Fatty Acid Synthases; Fatty Acids; Half-Life; Hydroxybutyrates; Ligases; Male; Models, Chemical; Pantothenic Acid; Rats; Tritium | 1971 |
[Influence of pantothenic acid on magnesium deficiency of the adult white rat].
Topics: Animals; Body Weight; Brain Chemistry; Coenzyme A; Kidney; Liver; Magnesium; Magnesium Deficiency; Male; Myocardium; Pantothenic Acid; Rats | 1971 |
Change in blood level of pantothenic acid and coenzyme A contents in the growing rat liver.
Topics: Adolescent; Animals; Body Weight; Brain Chemistry; Centrifugation; Child; Child, Preschool; Coenzyme A; Growth; Humans; Infant; Kidney; Liver; Pantothenic Acid; Rats; Spectrophotometry | 1967 |
Effect of pantothenic acid administration on 4'-phosphopantetheine and dephospho-CoA content in rat liver determined by the use of biosynthetic reaction of CoA in vitro from these precursor substances.
Topics: Animals; Body Weight; Coenzyme A; Enzyme Precursors; In Vitro Techniques; Liver; Organ Size; Pantothenic Acid; Phosphorus; Rats; Vitamin B Deficiency | 1967 |
[Effect of vitamin "A" and "E" supplements and of panthothenic acid on testicular coenzyme A].
Topics: Animals; Coenzyme A; Male; Pantothenic Acid; Rats; Testis; Vitamin A; Vitamins | 1967 |
[Thrombopoietin. Experimental bases and hemotherapeutic studies].
Topics: Animals; Blood Platelets; Blood Transfusion; Coenzyme A; Erythropoietin; Glutathione; Pantothenic Acid; Rabbits; Rats; Thrombocytopenia; Thrombocytosis; Thrombopoietin; Vitamins | 1967 |
Effects of dietary fat level on pantothenate depletion and liver fatty acid composition in the rat.
Topics: Adrenal Glands; Animals; Body Weight; Coenzyme A; Diet; Dietary Fats; Fatty Acids; Growth; Liver; Male; Organ Size; Pantothenic Acid; Phospholipids; Rats; Sterols; Triglycerides | 1968 |
Intestinal transport, coenzyme A, and colitis in pantothenic acid deficiency.
Topics: Animals; Biological Transport, Active; Cecum; Coenzyme A; Colitis, Ulcerative; Deficiency Diseases; Diarrhea; Intestinal Absorption; Intestinal Mucosa; Jejunum; Pantothenic Acid; Swine; Water-Electrolyte Balance | 1968 |
Incorporation of pantothenate-1-14C into pigeon liver fatty acid synthetase: 4'-phosphopantetheine, a prosthetic group of the multienzyme complex.
Topics: Animals; Carbon Isotopes; Cellulose; Chromatography, Ion Exchange; Coenzyme A; Columbidae; Electrophoresis; Ligases; Liver; Pantothenic Acid; Paper; Starvation; Time Factors; Transferases | 1968 |
Coenzyme A analogs. 3. The chemical synthesis of desulfopantetheine 4'-phosphate and its enzymatic conversion to desulfo-coenzyme A.
Topics: Chemical Phenomena; Chemistry; Coenzyme A; Pantothenic Acid; Phosphates; Phosphotransferases | 1968 |
S-palmityl pantetheine as an intermediate in the metabolism of palmityl Coenzyme A by rat liver plasma membrane preparations.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Coenzyme A; In Vitro Techniques; Liver; Membranes; Palmitic Acids; Pantothenic Acid; Rats | 1968 |
[Influence of pantothenic acid and coenzyme A on jejunal absorption of glucose].
Topics: Animals; Blood Glucose; Coenzyme A; Glucose; Intestinal Absorption; Jejunum; Liver Glycogen; Male; Pantothenic Acid; Perfusion; Rats | 1968 |
[Compensatory hypertrophy of the surviving kidney in nephrectomized animals. IV. Behavior of pantothenic acid and coenzyme A].
Topics: Animals; Coenzyme A; Hypertrophy; Kidney; Kidney Diseases; Nephrectomy; Pantothenic Acid; Postoperative Complications; Rats | 1968 |
Action of SH-containing compounds and of plasma from pantethine treated rabbits on platelet counts in irradiated rats.
Topics: Animals; Blood Cell Count; Blood Platelets; Coenzyme A; Glutathione; Methionine; Pantothenic Acid; Rabbits; Radiation Effects; Rats; Sulfhydryl Compounds | 1968 |
[Effects of coenzyme A and pantothenic acid on glycogen synthetase in the rat liver].
Topics: Adenosine Triphosphate; Animals; Coenzyme A; Glucosyltransferases; Glycogen; In Vitro Techniques; Ligases; Liver; Pantothenic Acid; Rats; Stimulation, Chemical | 1968 |
Investigations on pantothenic acid and its related compounds. XIX. Chemical studies. (9). Synthesis of 2'-ketopantothenic acid and 2',2''-diketopantethine.
Topics: Coenzyme A; Keto Acids; Pantothenic Acid | 1969 |
Formation of the thiazoline ring in pantetheine.
Topics: Benzoates; Chemical Phenomena; Chemistry; Chromatography, Paper; Coenzyme A; Drug Stability; Hot Temperature; Hydrogen-Ion Concentration; Pantothenic Acid; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Thiazoles; Time Factors; Ultraviolet Rays | 1969 |
Investigations on pantothenic acid and its related compounds. II. Biochemical studies. (1). Biosynthesis of coenzyme A from pantothenate, pantethine and from S-benzoylpantetheine in vitro and in vivo.
Topics: Animals; Coenzyme A; In Vitro Techniques; Mercaptoethylamines; Pantothenic Acid; Rats | 1965 |
A total synthesis of coenzyme A via thiazoline intermediate.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Coenzyme A; Pantothenic Acid; Thiazoles | 1965 |
Pantothenic acid and coenzyme A in the developing guinea-pig liver.
Topics: Animals; Animals, Newborn; Coenzyme A; Female; Fetus; Guinea Pigs; Liver; Pantothenic Acid; Pregnancy; Pregnancy, Animal | 1965 |
Growth of Mycoplasma gallisepticum strain J without serum.
Topics: Biotin; Coenzyme A; Culture Media; In Vitro Techniques; Mycoplasma; Pantothenic Acid; Vitamin B 12 | 1966 |
A simple radioisotopic assay for choline acetyltransferase and its application in the Lactobacillus plantarum system.
Topics: Acetylcholine; Acyltransferases; Carbon Isotopes; Chromatography, Paper; Coenzyme A; Lactobacillus; Pantothenic Acid | 1966 |
Balance studies on free and bound pantothenic acid in humans after administration of calcium pantothenate or coenzyme A.
Topics: Biological Assay; Coenzyme A; Hepatic Encephalopathy; Humans; Lactobacillus; Pantothenic Acid | 1966 |
A probable structure of the bifidus factor in carrot root.
Topics: Coenzyme A; Lactobacillus; Pantothenic Acid; Vegetables | 1966 |
[Coenzyme A content in the development cycle of Penicillium nigricans Bain--the producent of griseofulvin].
Topics: Coenzyme A; Glucose; Griseofulvin; Lipids; Pantothenic Acid; Penicillium | 1966 |
Experimental studies on liver coenzyme A. I. Seasonal variations of liver coenzyme A in pantothenic acid-deficient rats.
Topics: Animals; Coenzyme A; Female; Liver; Male; Pantothenic Acid; Rats; Seasons; Temperature; Vitamin B Deficiency | 1966 |
Experimental studies on liver coenzyme A. II. Coenzyme A and pantothenic acid levels in the liver of the rats treated with carbon tetrachloride, DL-ethionine or partially hepatectomized.
Topics: Animals; Carbon Tetrachloride; Coenzyme A; Ethionine; Female; Hepatectomy; Liver; Pantothenic Acid; Rats | 1966 |
Experimental studies on liver coenzyme A. 3. Effects of coenzyme A and pantethine upon liver coenzyme A and pantothenic acid contents of rats fed a pantothenic acid-deficient diet, or treated with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Coenzyme A; Liver; Pantothenic Acid; Rats; Vitamin B Deficiency | 1966 |
Pyruvate carboxylase. IX. Some properties of the activation by certain acyl derivatives of coenzyme A.
Topics: Animals; Carbon Dioxide; Chemical Phenomena; Chemistry; Coenzyme A; Enzymes; Hydrogen-Ion Concentration; In Vitro Techniques; Ligases; Liver; Pantothenic Acid; Poultry; Proteins; Pyruvates; Spectrophotometry; Surface-Active Agents; Ultracentrifugation | 1967 |
[On the detoxication of streptomycin by pantothenate].
Topics: Animals; Coenzyme A; Kidney; Pantothenic Acid; Rats; Streptomycin | 1967 |
A magnetic resonance study of the citrate synthase reaction.
Topics: Binding Sites; Butyrates; Chemical Phenomena; Chemistry, Physical; Citrates; Coenzyme A; Deuterium; Glutarates; Lyases; Magnetic Resonance Spectroscopy; Malates; Maleates; Pantothenic Acid; Pyruvates; Succinates | 1967 |
Investigations on pantothenic acid and its related compounds. IX. Biochemical studies.4. Separation and substrate specificity of pantothenate kinase and phosphopantothenoylcysteine synthetase.
Topics: Animals; Biological Assay; Chromatography; Coenzyme A; Cysteine; Ligases; Liver; Pantothenic Acid; Phosphotransferases; Rats | 1967 |
Investigations on pantothenic acid and its related compounds. XI. Biochemical studies. 6. A final stage in the biosynthesis of CoA.
Topics: Animals; Carboxy-Lyases; Coenzyme A; Enzyme Precursors; Liver; Nucleotidyltransferases; Pantothenic Acid; Phosphotransferases; Rats | 1967 |
Studies on the incorporation of 1-14C-pantothenate into the fatty acid synthetase complex of baker's yeast.
Topics: Acyltransferases; Carbon Isotopes; Coenzyme A; Fatty Acids; Ligases; Nucleotides; Oxidoreductases; Pantothenic Acid; Proteins; Saccharomyces; Spectrophotometry; Sulfhydryl Compounds | 1967 |
Investigations on pantothenic acid and its related compounds. X. Biochemical studies. 5. Purification and substrate specificity of phosphopantothenoylcysteine decarboxylase from rat liver.
Topics: Animals; Biological Assay; Carbon Dioxide; Carboxy-Lyases; Chromatography; Coenzyme A; Cysteine; Lactobacillus; Liver; Pantothenic Acid; Rats | 1967 |
Involvement of acyl carrier protein in acylation of glycerol 3-phosphate in Clostridium butyricum. I. Purification of Clostridium butyricum acyl carrier protein and synthesis of long chain acyl derivatives of acyl carrier protein.
Topics: Alkylation; Amino Acids; Autoanalysis; Bacterial Proteins; Carbon Isotopes; Cellulose; Centrifugation, Zonal; Chromatography; Chromatography, Gel; Clostridium; Coenzyme A; Fatty Acids; Pantothenic Acid; Protein Binding; Sulfhydryl Compounds; Tritium | 1967 |
Differential effects of cysteine on protein and coenzyme A synthesis in rat heart.
Topics: Animals; Bicarbonates; Buffers; Carbon Radioisotopes; Coenzyme A; Cysteine; Cystine; Dextrans; Dithiothreitol; Heart; Male; Myocardium; Pantothenic Acid; Perfusion; Phenanthrolines; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfur Radioisotopes | 1984 |
Altered coenzyme A and carnitine metabolism in pressure-overload hypertrophied hearts.
Topics: Animals; Body Weight; Cardiac Output; Cardiomegaly; Carnitine; Cats; Coenzyme A; Female; Heart Ventricles; Male; Myocardium; Organ Size; Pantothenic Acid; Pressure | 1983 |
Coenzyme A-synthesizing protein complex of Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Carboxy-Lyases; Coenzyme A; Cysteine; Enzyme Inhibitors; Multienzyme Complexes; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Substrate Specificity; Temperature | 1980 |
Regulation of coenzyme A biosynthesis by glucagon and glucocorticoid in adult rat liver parenchymal cells.
Topics: Animals; Bucladesine; Cells, Cultured; Coenzyme A; Cycloheximide; Dexamethasone; Glucagon; Glucocorticoids; Insulin; Liver; Male; Pantothenic Acid; Rats; Theophylline | 1980 |
The effect of ethanol and acetaldehyde on [14C]pantothenate incorporation into CoA in cultured rat liver parenchymal cells.
Topics: Acetaldehyde; Animals; Bucladesine; Cells, Cultured; Coenzyme A; Dexamethasone; Ethanol; Glucagon; Liver; Pantothenic Acid; Rats; Theophylline | 1982 |
A high yield method for the preparative synthesis of coenzyme A by combination of chemical and enzymic reactions.
Topics: Brevibacterium; Coenzyme A; Feedback; Kinetics; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Substrate Specificity | 1983 |
Pantothenate kinase and control of CoA synthesis in heart.
Topics: Animals; Coenzyme A; Cysteine; Glucose; Male; Myocardium; Pantothenic Acid; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Metabolism of 4'-phosphopantetheine in Escherichia coli.
Topics: Acyl Carrier Protein; Alanine; Coenzyme A; Escherichia coli; Pantetheine; Pantothenic Acid; Sulfhydryl Compounds | 1984 |
Pantethine and pantothenate effect on the CoA content of rat liver.
Topics: Animals; Coenzyme A; Cysteine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1984 |
[Antitoxic properties of pantothenic acid derivatives, precursors of coenzyme A biosynthesis, with regard to kanamycin].
Topics: Animals; Antidotes; Brain; Chemical and Drug Induced Liver Injury; Coenzyme A; Drug Evaluation, Preclinical; Female; Kanamycin; Liver; Male; Mice; Pantothenic Acid | 1984 |
Hydrolysis and absorption of pantothenate and its coenzymes in the rat small intestine.
Topics: Absorption; Animals; Carbon Radioisotopes; Coenzyme A; Coenzymes; Hydrolysis; Intestine, Small; Male; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains | 1983 |
[Electrocardiogram changes in the rat by coenzyme A action].
Topics: Adenosine; Animals; Coenzyme A; Cysteine; Electrocardiography; Heart; Pantetheine; Pantothenic Acid; Rats | 1984 |
Regulation of coenzyme A biosynthesis.
Topics: Acyl Carrier Protein; beta-Alanine; Coenzyme A; Escherichia coli; Organophosphorus Compounds; Pantetheine; Pantothenic Acid | 1981 |
Regulation of coenzyme A synthesis in heart muscle: effects of diabetes and fasting.
Topics: Alloxan; Animals; Coenzyme A; Diabetes Mellitus, Experimental; Fasting; Glucagon; Insulin; Kinetics; Male; Myocardium; Pantothenic Acid; Rats | 1981 |
A mutant of Escherichia coli conditionally defective in the synthesis of holo-[acyl carrier protein].
Topics: Acyl Carrier Protein; Coenzyme A; Escherichia coli; Ethyl Methanesulfonate; Mutation; Pantothenic Acid | 1981 |
Genetic and biochemical analyses of pantothenate biosynthesis in Escherichia coli and Salmonella typhimurium.
Topics: Carboxy-Lyases; Chromosome Mapping; Chromosomes, Bacterial; Coenzyme A; Escherichia coli; Genes, Bacterial; Hydroxymethyl and Formyl Transferases; Pantothenic Acid; Peptide Synthases; Salmonella typhimurium; Transferases | 1982 |
Coenzyme A metabolism in pantothenic acid-deficient rats.
Topics: Animals; Coenzyme A; Diabetes Mellitus, Experimental; Fasting; Growth; Male; Pantothenic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Rate-limiting step and control of coenzyme A synthesis in cardiac muscle.
Topics: Animals; Chromatography, High Pressure Liquid; Coenzyme A; Cysteine; Cytosol; Dithiothreitol; Heart; Kinetics; Male; Mitochondria, Heart; Myocardium; Pantothenic Acid; Perfusion; Rats; Rats, Inbred Strains; Subcellular Fractions | 1982 |
Assay of the enzymatic hydrolysis of pantetheine.
Topics: Animals; Carbon Radioisotopes; Coenzyme A; Cysteamine; Hydrolysis; In Vitro Techniques; Kidney Cortex; Pantetheine; Pantothenic Acid; Substrate Specificity; Sulfhydryl Compounds; Swine | 1982 |
The effects of high dietary supplements of copper sulphate on pantothenic acid metabolism in the chick.
Topics: Animals; Body Weight; Chickens; Coenzyme A; Copper; Food, Fortified; Liver; Pantothenic Acid; Poultry Diseases | 1981 |
Effects of diabetes and fasting on pantothenic acid metabolism in rats.
Topics: Animals; Coenzyme A; Diabetes Mellitus, Experimental; Fasting; Kidney; Kinetics; Liver; Male; Muscles; Myocardium; Organ Size; Pantothenic Acid; Rats | 1981 |
A subcellular study of the clofibrate-induced increase in coenzyme A concentration in rat liver.
Topics: Animals; Clofibrate; Coenzyme A; Cytochromes; Cytosol; Glutamate Dehydrogenase; Liver; Male; Mitochondria, Liver; Pantothenic Acid; Rats; Subcellular Fractions | 1980 |
Separation of coenzyme A and its precursors by reversed-phase high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Coenzyme A; Liver; Microchemistry; Pantothenic Acid; Rats | 1980 |
Hydroxycobalamin[c-lactam] increases total coenzyme A content in primary culture hepatocytes by accelerating coenzyme A biosynthesis secondary to Acyl-CoA accumulation.
Topics: Acyl Coenzyme A; Animals; Biodegradation, Environmental; Carbon Radioisotopes; Cells, Cultured; Coenzyme A; Liver; Male; Pantothenic Acid; Rats; Rats, Sprague-Dawley; Vitamin B 12 | 1993 |
Reversal of the adverse chronic effects of the unsaturated derivative of valproic acid--2-n-propyl-4-pentenoic acid--on ketogenesis and liver coenzyme A metabolism by a single injection of pantothenate, carnitine, and acetylcysteine in developing mice.
Topics: Acetylcysteine; Animals; Carnitine; Coenzyme A; Fatty Acids, Monounsaturated; Ketone Bodies; Liver; Mice; Pantothenic Acid | 1993 |
Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Coenzyme A; Fatty Acids; Female; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Mice; Palmitic Acid; Palmitic Acids; Pantetheine; Pantothenic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Pantothenic acid and coenzyme A in experimental cisplatin-induced ototoxia.
Topics: Animals; Antineoplastic Agents; Cisplatin; Cochlea; Coenzyme A; Deafness; Drug Therapy, Combination; Guinea Pigs; Pantothenic Acid | 1996 |
Metabolic requirements for the hepatocellular proliferation induced by peroxisome proliferators. Role of coenzyme A.
Topics: Animals; Cell Division; Coenzyme A; Liver; Male; Microbodies; Pantothenic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Mitochondrial, but not peroxisomal, beta-oxidation of fatty acids is conserved in coenzyme A-deficient rat liver.
Topics: Animals; Coenzyme A; Fatty Acids; Liver; Male; Microbodies; Mitochondria, Liver; Oxidation-Reduction; Pantothenic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Pantothenol protects rats against some deleterious effects of gamma radiation.
Topics: Animals; Antioxidants; beta Carotene; Cholesterol; Coenzyme A; Drug Administration Schedule; Female; Gamma Rays; Glutathione; Glutathione Disulfide; Intubation, Gastrointestinal; Lactic Acid; Lipids; Liver; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); NAD; Pantothenic Acid; Phospholipids; Proteins; Pyruvic Acid; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances | 1998 |
Dietary pantothenic acid requirement of juvenile grass shrimp, Penaeus monodon.
Topics: Animals; Coenzyme A; Digestive System; Lipid Metabolism; Nutritional Requirements; Pantothenic Acid; Penaeidae; Weight Gain | 1999 |
The Aspergillus nidulans panB gene encodes ketopantoate hydroxymethyltransferase, required for biosynthesis of pantothenate and Coenzyme A.
Topics: Amino Acid Sequence; Aspergillus nidulans; Coenzyme A; Conserved Sequence; Escherichia coli; Eukaryotic Cells; Gene Expression; Genes, Fungal; Hydroxymethyl and Formyl Transferases; Molecular Sequence Data; Pantothenic Acid; Prokaryotic Cells; Recombinant Proteins; Restriction Mapping; Sequence Analysis, DNA | 1999 |
Reduced flux through the purine biosynthetic pathway results in an increased requirement for coenzyme A in thiamine synthesis in Salmonella enterica serovar typhimurium.
Topics: Adenine; Alcohol Oxidoreductases; Cell Division; Coenzyme A; Culture Media; Mutation; Pantothenic Acid; Purines; Salmonella typhimurium; Thiamine; Thiamine Pyrophosphate | 2000 |
Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Chromatography, Gel; Coenzyme A; Cysteine; Escherichia coli; Flavin Mononucleotide; Flavoproteins; Molecular Sequence Data; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptides; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 2000 |
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS.
Topics: Aerobiosis; Amino Acids; Animals; Aphids; Biological Transport; Buchnera; Coenzyme A; DNA, Bacterial; Evolution, Molecular; Genome, Bacterial; Lipopolysaccharides; Molecular Sequence Data; Open Reading Frames; Pantothenic Acid; Phospholipids; Rec A Recombinases; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Symbiosis | 2000 |
Significance of pantothenate for glucose fermentation by Oenococcus oeni and for suppression of the erythritol and acetate production.
Topics: Acetates; Acetyl Coenzyme A; Aldehyde Oxidoreductases; Coenzyme A; Culture Media; Erythritol; Fermentation; Glucose; Gram-Positive Cocci; Leuconostoc; Pantothenic Acid; Phosphate Acetyltransferase | 2001 |
Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria.
Topics: Adenosine Triphosphate; Carboxy-Lyases; Cloning, Molecular; Coenzyme A; Cysteine; Cytidine Monophosphate; Cytidine Triphosphate; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavins; Kinetics; Models, Chemical; Pantothenic Acid; Peptide Synthases; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Ultraviolet Rays | 2001 |
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography, Gel; Coenzyme A; Crystallography, X-Ray; Cysteine; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Models, Chemical; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptide Synthases; Plant Proteins; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Salts; Sequence Homology, Amino Acid; Signal Transduction; Time Factors | 2001 |
Mechanistic studies on phosphopantothenoylcysteine decarboxylase.
Topics: Carboxy-Lyases; Catalysis; Coenzyme A; Cysteine; Cytidine Monophosphate; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Molecular Structure; Pantetheine; Pantothenic Acid; Peptide Synthases; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2001 |
Prebiotic syntheses of vitamin coenzymes: II. Pantoic acid, pantothenic acid, and the composition of coenzyme A.
Topics: 4-Butyrolactone; Adenosine Triphosphate; Alanine; Aldehydes; Coenzyme A; Coenzymes; Glycine; Hemiterpenes; Hydrogen-Ion Concentration; Hydroxybutyrates; Keto Acids; Pantothenic Acid; Protein Precursors | 1993 |
Elevated levels of ketopantoate hydroxymethyltransferase (PanB) lead to a physiologically significant coenzyme A elevation in Salmonella enterica serovar Typhimurium.
Topics: Coenzyme A; Hydroxymethyl and Formyl Transferases; Operon; Pantothenic Acid; Promoter Regions, Genetic; Salmonella typhimurium; Thiamine | 2002 |
The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite.
Topics: Anti-Bacterial Agents; Base Sequence; Chromatography, High Pressure Liquid; Coenzyme A; DNA Primers; Escherichia coli; Microbial Sensitivity Tests; Pantothenic Acid | 2002 |
Pantothenic acid: an organ-specific pro-oxidant vitamin. Brain and liver neuroprostane levels in rats fed a pantothenic acid-deficient diet.
Topics: Animals; Brain; Coenzyme A; Docosahexaenoic Acids; Liver; Male; Pantothenic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Role of feedback regulation of pantothenate kinase (CoaA) in control of coenzyme A levels in Escherichia coli.
Topics: Binding Sites; Coenzyme A; Culture Media; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor) | 2003 |
Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Coenzyme A; DNA, Bacterial; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Sequence Alignment; Staphylococcal Infections; Staphylococcus aureus; Tumor Cells, Cultured | 2003 |
On chemistry and function of coenzyme A.
Topics: Coenzyme A; Coenzymes; Pantothenic Acid | 1953 |
The synthesis of coenzyme A by Lactobacillus arabinosus 17-5.
Topics: Coenzyme A; Coenzymes; Lactobacillus; Lactobacillus plantarum; Pantothenic Acid | 1954 |
Biosynthesis of coenzyme A from phospho-pantetheine and of pantetheine from pantothenate.
Topics: Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1954 |
[The growth of Lactobacillus helveticus in the presence of pantothenic acid and pantetheine, and its application to the microbiological determination of coenzyme A in tissues].
Topics: Biological Phenomena; Coenzyme A; Coenzymes; Health Services; Lactobacillus; Lactobacillus helveticus; Pantetheine; Pantothenic Acid; Physiological Phenomena | 1955 |
Effect of coenzyme A on the metabolic oxidation of labeled fatty acids: rate studies, instrumentation and liver fractionation.
Topics: Biochemical Phenomena; Coenzyme A; Coenzymes; Fatty Acids; Lipid Metabolism; Liver; Oxidation-Reduction; Pantothenic Acid | 1956 |
In vitro effect of two pantheine analogues on coenzyme A requiring systems.
Topics: Coenzyme A; Coenzymes; In Vitro Techniques; Inorganic Chemicals; Liver; Organic Chemicals; Pantothenic Acid; Sulfides | 1956 |
Enzymatic release of pantetheine from coenzyme A in animal tissues and its microbiological determination.
Topics: Animals; Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1957 |
[Determination of coenzyme A in tissues; microbiological evaluation by measuring pantotheine liberation by enzymic hydrolysis].
Topics: Coenzyme A; Coenzymes; Hydrolysis; Lactobacillus; Pantothenic Acid | 1957 |
Effects of orotic acid on coenzyme A and pantothenic acid of liver in vitamin B12 deficiency.
Topics: Biochemical Phenomena; Coenzyme A; Coenzymes; Congenital Abnormalities; Liver; Orotic Acid; Pantothenic Acid; Vitamin B 12 Deficiency | 1958 |
[Pantothenic acid (coenzyme A) and ossification].
Topics: Coenzyme A; Humans; Pantothenic Acid; Rickets; Sulfides | 1957 |
[Coenzyme A in rat liver during administration of pantothenic acid and nicotinamide].
Topics: Coenzyme A; Coenzymes; Liver; Niacin; Niacinamide; Nicotinic Acids; Pantothenic Acid | 1958 |
[DEMONSTRATION AND LOCALIZATION IN THE PIGEON LIVER OF THE ENZYME SYSTEM CATALYZING THE SYNTHESIS OF COENZYME A FROM PANTOTHENIC ACID].
Topics: Animals; Birds; Coenzyme A; Columbidae; Liver; Metabolism; Pantothenic Acid; Phosphotransferases; Physiological Phenomena; Physiology, Comparative; Research | 1964 |
PANTOTHENIC ACID: ITS METABOLIC EFFECTS IN NORMAL CHILDREN.
Topics: 17-Ketosteroids; Adolescent; Aspartate Aminotransferases; Biomedical Research; Blood; Blood Cell Count; Blood Proteins; Body Weight; Ceruloplasmin; Child; Cholesterol; Coenzyme A; Electrolytes; Hemoglobins; Humans; Metabolism; Pantothenic Acid; Pharmacology; Pituitary-Adrenal Function Tests; Serum Albumin; Serum Globulins; Urine | 1964 |
EFFECTS OF VINCA ROSEA LINN. ALKALOIDS ON THE LIVER COENZYME A AND PANTOTHENIC ACID.
Topics: Alkaloids; Catharanthus; Coenzyme A; Liver; Pantothenic Acid; Pharmacology; Rats; Research | 1963 |
ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN.
Topics: Acyl Carrier Protein; Alkaline Phosphatase; Amines; Carbon Isotopes; Chemistry Techniques, Analytical; Chromatography; Coenzyme A; Electrophoresis; Lactobacillus; Lactones; Metabolism; Pantetheine; Pantothenic Acid; Pepsin A; Peptide Hydrolases; Phosphates; Protein Hydrolysates; Proteins; Radiometry; Research | 1965 |
PANTOTHENIC ACID AND COENZYME A IN THE ORGANS OF RATS IN PANTOTHENIC ACID DEFICIENCY AND ITS RECOVERY.
Topics: Biochemical Phenomena; Biochemistry; Biological Assay; Body Weight; Coenzyme A; Lactobacillus; Pantothenic Acid; Rats; Research; Vitamin B Deficiency | 1965 |
IDENTITY OF A BOVINE LIVER NUCLEOTIDE-PEPTIDE WITH THE UNSYMMETRICAL DISULFIDE OF COENZYME A AND GLUTATHIONE.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Coenzyme A; Disulfides; Glutathione; Liver; Nucleotides; Pantothenic Acid; Peptides; Research; Sulfides | 1965 |
The chemistry of pantothenic acid pantetheine and coenzyme A.
Topics: Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1954 |
[Comparison of the action of coenzyme A derivatives on the growth of cells in tissue cultures].
Topics: Biological Phenomena; Coenzyme A; Ethylamines; Pantothenic Acid; Physiological Phenomena; Research Design; Tissue Culture Techniques | 1955 |
[Pantothenic acid and coenzyme A of the liver in the vitamin B-12 deficient chick].
Topics: Animals; Biochemical Phenomena; Chickens; Coenzyme A; Coenzymes; Liver; Pantothenic Acid; Vitamin B 12 Deficiency; Vitamins | 1959 |
One-pot chemoenzymatic preparation of coenzyme A analogues.
Topics: Base Sequence; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Coenzyme A; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Molecular Sequence Data; Molecular Structure; Nucleotidyltransferases; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins | 2004 |
Relation of the Lactobacillus bulgaricus factor to pantothenic acid and coenzyme A.
Topics: Coenzyme A; Lactobacillus; Pantothenic Acid | 1950 |
Levels and intracellular distribution of coenzyme A and pantothenic acid in rat liver and tumors.
Topics: Animals; Coenzyme A; Coenzymes; Cytoplasm; Liver; Neoplasms; Pantothenic Acid; Rats | 1950 |
The comparative activities of pantethine, pantothenic acid, and coenzyme A for various microorganisms.
Topics: Coenzyme A; Humans; Pantetheine; Pantothenic Acid | 1951 |
Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.
Topics: Anti-Bacterial Agents; Calcium; Catalysis; Coenzyme A; Fatty Acids; Ionophores; Lactones; Pantothenic Acid; Peptide Fragments; Peptide Synthases; Peptides; Peptides, Cyclic; Protein Structure, Tertiary; Recombinant Fusion Proteins; Stereoisomerism; Streptomyces; Thioredoxins | 2004 |
Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics.
Topics: Archaea; Carboxy-Lyases; Coenzyme A; Escherichia coli; Evolution, Molecular; Genomics; Humans; Pantothenic Acid; Peptide Synthases; Phylogeny | 2004 |
Systemic lupus erythematosus: a combined deficiency disease.
Topics: Coenzyme A; Diet; Female; Humans; Lupus Erythematosus, Systemic; Male; Models, Theoretical; Pantothenic Acid; Sex Factors; Steroids; Vitamins | 2004 |
Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.
Topics: Acetates; Acyl Carrier Protein; Antimetabolites; Biological Transport; Blotting, Western; Chromatography, Gel; Coenzyme A; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Fatty Acids; Hydrolysis; Lipid Metabolism; Lipids; Mass Spectrometry; Models, Chemical; Pantothenic Acid; Phosphorylation; Protein Binding; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Streptococcus pneumoniae; Substrate Specificity; Time Factors | 2004 |
Characterization of a new pantothenate kinase isoform from Helicobacter pylori.
Topics: Acetyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Bacillus subtilis; Cloning, Molecular; Coenzyme A; Enzyme Inhibitors; Gene Expression; Helicobacter pylori; Isoenzymes; Kinetics; Molecular Sequence Data; Multigene Family; NAD; Oxidation-Reduction; Pantothenic Acid; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Folding; Sequence Alignment | 2005 |
Pantothenic acid quantification: method comparison of a stable isotope dilution assay and a microbiological assay.
Topics: Amidohydrolases; Amylases; Animals; Carbon Isotopes; Coenzyme A; Dairy Products; Food Analysis; GPI-Linked Proteins; Indicator Dilution Techniques; Isotopes; Lactobacillus plantarum; Meat; Nitrogen Isotopes; Pantothenic Acid; Papain; Phosphoric Monoester Hydrolases; Plants, Edible; Sensitivity and Specificity | 2005 |
One-pot chemo-enzymatic synthesis of reporter-modified proteins.
Topics: Affinity Labels; Carrier Proteins; Coenzyme A; Enzymes; Fluorescent Dyes; Molecular Probe Techniques; Pantothenic Acid; Proteins; Substrate Specificity; Transferases | 2006 |
Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology.
Topics: Amino Acid Sequence; Bacillus anthracis; Coenzyme A; Crystallization; Crystallography, X-Ray; Models, Molecular; Molecular Sequence Data; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Sequence Alignment | 2007 |
Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.
Topics: Animals; Carnitine; Coenzyme A; Female; gamma-Aminobutyric Acid; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Homeostasis; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Nootropic Agents; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor) | 2007 |
Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite.
Topics: Animals; Biological Transport, Active; Coenzyme A; Cytoplasm; Erythrocyte Membrane; Furosemide; Humans; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Protein Binding; Protozoan Proteins; Sodium Potassium Chloride Symporter Inhibitors; Vitamin B Complex | 2007 |
How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Carboxy-Lyases; Coenzyme A; Escherichia coli; Genetic Complementation Test; Kinetics; Mycobacterium tuberculosis; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Substrate Specificity; Thermodynamics | 2007 |
The liberation of pantothenic acid from coenzyme A.
Topics: Coenzyme A; Enzymes; Humans; Pantothenic Acid | 1949 |
Coenzyme A and citrate formation in homogenates of heart ventricle from normal and pantothenic acid-deficient ducklings.
Topics: Animals; Avitaminosis; Citrates; Citric Acid; Coenzyme A; Ducks; Heart Ventricles; Pantothenic Acid; Vitamin B Complex; Vitamins | 1949 |
The effect of pantothenic acid deficiency upon the coenzyme A content and pyruvate utilization of rat and duck tissues.
Topics: Animals; Aquatic Organisms; Coenzyme A; Ducks; Pantothenic Acid; Pyruvates; Pyruvic Acid; Rats | 1948 |
The pantothenic acid content of coenzyme A by chick assay.
Topics: Animals; Biological Assay; Chickens; Coenzyme A; Humans; Pantothenic Acid | 1948 |
Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization.
Topics: Amines; Cell Proliferation; Coenzyme A; Enzyme Inhibitors; Escherichia coli; Kinetin; Nitrogen; Pantothenic Acid | 2008 |
The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme.
Topics: Acetyl-CoA C-Acyltransferase; Bacterial Proteins; Binding Sites; Coenzyme A; Cysteine; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Pantothenic Acid; Serine; Substrate Specificity; Sulfhydryl Compounds; Sulfur | 2008 |
Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Coenzyme A; Crystallization; Crystallography, X-Ray; Escherichia coli Proteins; Factor VIIa; Ligands; Models, Molecular; Mycobacterium tuberculosis; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Conformation; Recombinant Proteins; Species Specificity | 2009 |
The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.
Topics: Animals; Chromatography, High Pressure Liquid; Coenzyme A; Erythrocyte Membrane; Erythrocytes; Humans; Malaria, Falciparum; Models, Biological; Models, Chemical; Pantothenic Acid; Phosphorylation; Plasmodium falciparum; Protozoan Proteins; Time Factors | 2009 |
Antibacterial activity of N-pentylpantothenamide is due to inhibition of coenzyme a synthesis.
Topics: Acyl Carrier Protein; Anti-Bacterial Agents; Coenzyme A; Escherichia coli K12; Escherichia coli Proteins; Microbial Sensitivity Tests; Pantothenic Acid; Phosphoric Diester Hydrolases | 2010 |
Bacterial conversion of pantothenic acid into coenzyme A (acetylation) and its relation to pyruvic oxidation.
Topics: Acetylation; Coenzyme A; Oxidation-Reduction; Pantothenic Acid; Pyruvic Acid; Vitamin B Complex; Vitamins | 1947 |
Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters.
Topics: Animals; Cells, Cultured; Chromatography, Liquid; Coenzyme A; Esters; Hepatocytes; Isotope Labeling; Mice; Pantothenic Acid; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2011 |
Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics.
Topics: Arginine; Coenzyme A; Embryonic Stem Cells; Glutathione; Humans; Metabolomics; Niacin; Niacinamide; Pantothenic Acid; Proline; Toxicity Tests | 2011 |
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.
Topics: Adolescent; Adult; Bile Acids and Salts; Child; Child, Preschool; Codon, Nonsense; Coenzyme A; Cohort Studies; Female; Humans; Iron Metabolism Disorders; Lactic Acid; Lipid Metabolism; Lipid Metabolism Disorders; Male; Metabolome; Mitochondria; Neuroaxonal Dystrophies; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Sphingomyelins; Young Adult | 2012 |
The missing link in coenzyme A biosynthesis: PanM (formerly YhhK), a yeast GCN5 acetyltransferase homologue triggers aspartate decarboxylase (PanD) maturation in Salmonella enterica.
Topics: Acetyltransferases; Amino Acid Sequence; Carboxy-Lyases; Coenzyme A; Corynebacterium glutamicum; Molecular Sequence Data; Pantothenic Acid; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Salmonella typhimurium; Sequence Homology, Amino Acid | 2012 |
The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.
Topics: Anti-Bacterial Agents; Antimetabolites; Coenzyme A; Humans; Pantothenic Acid; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus | 2012 |
Simultaneous high-performance liquid chromatography determination of coenzyme A, dephospho-coenzyme A, and acetyl-coenzyme A in normal and pantothenic acid-deficient rats.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Chromatography, High Pressure Liquid; Coenzyme A; Diet; Male; Pantothenic Acid; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet | 2012 |
A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.
Topics: Adenosine Triphosphate; Alanine; Archaeal Proteins; Coenzyme A; Kinetics; Pantothenic Acid; Peptide Synthases; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Thermococcus | 2012 |
Identification of pantoate kinase and phosphopantothenate synthetase from Methanospirillum hungatei.
Topics: Coenzyme A; Escherichia coli; Ligases; Methanospirillum; Pantothenic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Uridine Triphosphate | 2013 |
PanG, a new ketopantoate reductase involved in pantothenate synthesis.
Topics: 4-Butyrolactone; Alcohol Oxidoreductases; Animals; Clostridioides difficile; Coenzyme A; Coxiella burnetii; Enterococcus faecalis; Escherichia coli; Francisella tularensis; Mice; Pantothenic Acid; Tularemia | 2013 |
Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.
Topics: Amides; Amidohydrolases; Antimalarials; Cells, Cultured; Coenzyme A; Erythrocytes; GPI-Linked Proteins; Humans; Malaria, Falciparum; Pantothenic Acid; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Recombinant Proteins | 2013 |
Pantothenic acid refeeding diminishes the liver, perinephrical fats, and plasma fats accumulated by pantothenic acid deficiency and/or ethanol consumption.
Topics: Animals; Coenzyme A; Diet; Ethanol; Fatty Liver; Kidney; Lipid Metabolism; Lipids; Liver; Male; Pantothenic Acid; Rats; Rats, Wistar; Vitamin B Complex; Vitamin B Deficiency; Weaning | 2013 |
D-pantethine has vitamin activity equivalent to d-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats.
Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet; Male; Organ Size; Pantetheine; Pantothenic Acid; Rats; Rats, Wistar; Vitamins; Weaning | 2013 |
Label-free quantitative proteomics analysis of antibiotic response in Staphylococcus aureus to oxacillin.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Coenzyme A; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Methicillin-Resistant Staphylococcus aureus; Oxacillin; Pantothenic Acid; Penicillin-Binding Proteins; Peptidoglycan; Proteome; Staphylococcus aureus | 2014 |
Antimicrobial activity of pantothenol against staphylococci possessing a prokaryotic type II pantothenate kinase.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Proteins; Biosynthetic Pathways; Coenzyme A; Escherichia coli K12; Humans; Microbial Sensitivity Tests; Pantothenic Acid; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pseudomonas putida; Staphylococcal Infections; Staphylococcus | 2014 |
Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase.
Topics: Catalytic Domain; Coenzyme A; Escherichia coli; Models, Molecular; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Structure-Activity Relationship | 2014 |
Pantothenic acid biosynthesis in the parasite Toxoplasma gondii: a target for chemotherapy.
Topics: Amino Acid Sequence; Cell Line; Cloning, Molecular; Coenzyme A; Humans; Mycobacterium tuberculosis; Opportunistic Infections; Pantothenic Acid; Peptide Synthases; Sequence Alignment; Toxoplasma; Toxoplasmosis | 2014 |
Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis.
Topics: Amides; Anti-Bacterial Agents; Binding Sites; Coenzyme A; Drug Design; Isoenzymes; Kinetics; Molecular Structure; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Staphylococcus aureus; Vitamin B Complex | 2014 |
The STM4195 gene product (PanS) transports coenzyme A precursors in Salmonella enterica.
Topics: Amino Acid Sequence; Bacterial Proteins; Biological Transport; Carrier Proteins; Coenzyme A; Gene Expression Regulation, Bacterial; Molecular Structure; Mutation; Pantothenic Acid; Salmonella enterica | 2015 |
The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A.
Topics: Amino Acid Sequence; Biocatalysis; Coenzyme A; Glutamate Decarboxylase; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Molecular Sequence Data; Mutagenesis; Pantothenic Acid; Protein Binding; Protein Interaction Domains and Motifs; Scattering, Small Angle; Sequence Alignment; X-Ray Diffraction | 2015 |
Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.
Topics: Administration, Oral; Amides; Animals; Coenzyme A; Disease Models, Animal; Embryo, Mammalian; Female; Fibroblasts; Gene Expression; Humans; Liver; Male; Mice; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphoric Acids; Phosphotransferases (Alcohol Group Acceptor); Primary Cell Culture | 2015 |
Cirrhosis related functionality characteristic of the fecal microbiota as revealed by a metaproteomic approach.
Topics: Amino Acids, Branched-Chain; Carbohydrate Metabolism; Coenzyme A; Feces; Female; Gastrointestinal Microbiome; Humans; Liver Cirrhosis; Male; Metagenome; Middle Aged; Pantothenic Acid; Proteomics; Severity of Illness Index; Spouses | 2016 |
Urinary metabolomics of young Italian autistic children supports abnormal tryptophan and purine metabolism.
Topics: Autism Spectrum Disorder; Biomarkers; Case-Control Studies; Child; Child, Preschool; Chromatography, High Pressure Liquid; Coenzyme A; Dysbiosis; Female; Humans; Hydrophobic and Hydrophilic Interactions; Indoleacetic Acids; Italy; Kynurenic Acid; Male; Melatonin; Metabolomics; Pantothenic Acid; Purines; Pyrimidines; Quinolinic Acid; Riboflavin; Tryptophan; Vitamin B 6; Xanthurenates | 2016 |
Antiplasmodial Mode of Action of Pantothenamides: Pantothenate Kinase Serves as a Metabolic Activator Not as a Target.
Topics: Antimalarials; Antimetabolites; beta-Alanine; Biotransformation; Carbon Radioisotopes; Coenzyme A; Erythrocytes; Humans; Kinetics; Models, Molecular; Pantothenic Acid; Parasitic Sensitivity Tests; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Protein Binding; Protozoan Proteins; Structure-Activity Relationship | 2017 |
The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZ·AcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan).
Topics: Acetyl Coenzyme A; Amino Acid Substitution; Anti-Bacterial Agents; Antimetabolites; Binding Sites; Calorimetry; Carboxy-Lyases; Coenzyme A; Crystallography, X-Ray; Enzyme Activation; Escherichia coli K12; Escherichia coli Proteins; Gene Deletion; Glutamate Decarboxylase; Kinetics; Models, Molecular; Mutation; Pantothenic Acid; Protein Conformation; Protein Multimerization; Recombinant Proteins; Titrimetry | 2017 |
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease.
Topics: Acetyl Coenzyme A; Adolescent; Biopsy; Brain; Cell Differentiation; Child; Coenzyme A; Female; Fibroblasts; Humans; Induced Pluripotent Stem Cells; Iron; Karyotyping; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Mutation; NAD; Neurons; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Reactive Oxygen Species | 2017 |
Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models.
Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Coenzyme A; Disease Models, Animal; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Neurons; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Rats, Sprague-Dawley; RNA Interference; Species Specificity | 2018 |
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
Topics: Animals; Antimalarials; Coenzyme A; Drug Resistance; Erythrocytes; Malaria; Mutation; Pantothenic Acid; Parasitic Sensitivity Tests; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Protozoan Proteins | 2018 |
Physiologic and metabolic characterization of Saccharomyces cerevisiae reveals limitations in the synthesis of the triterpene squalene.
Topics: Coenzyme A; Culture Media; Ethanol; Glucose; Pantothenic Acid; Saccharomyces cerevisiae; Squalene | 2018 |
Overexpression of Human Mutant PANK2 Proteins Affects Development and Motor Behavior of Zebrafish Embryos.
Topics: Animals; Animals, Genetically Modified; Coenzyme A; Embryo, Nonmammalian; Embryonic Development; Humans; Loss of Function Mutation; Motor Activity; Mutation, Missense; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; RNA, Messenger; Transgenes; Up-Regulation; Zebrafish; Zebrafish Proteins | 2019 |
Pantothenate Rescues Iron Accumulation in Pantothenate Kinase-Associated Neurodegeneration Depending on the Type of Mutation.
Topics: Cell Death; Cell Shape; Coenzyme A; Energy Metabolism; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Iron; Lipid Peroxidation; Lipofuscin; Mitochondria; Mutation; Neurons; Neuroprotective Agents; Oxidative Stress; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Protein Carbonylation | 2019 |
The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors.
Topics: Amphotericin B; Antifungal Agents; Coenzyme A; Drug Resistance, Fungal; Ergosterol; Gene Expression Regulation, Fungal; Genome, Fungal; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Saccharomyces cerevisiae; Sterols; Terbinafine | 2019 |
UPLC-MS-based urine nontargeted metabolic profiling identifies dysregulation of pantothenate and CoA biosynthesis pathway in diabetic kidney disease.
Topics: Biosynthetic Pathways; Chromatography, High Pressure Liquid; Coenzyme A; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Mass Spectrometry; Metabolome; Middle Aged; Pantothenic Acid | 2020 |
Chronic pantothenic acid supplementation does not affect muscle coenzyme A content or cycling performance.
Topics: Acetyl Coenzyme A; Adult; Athletic Performance; Bicycling; Coenzyme A; Dietary Supplements; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Pantothenic Acid; Sports Nutritional Physiological Phenomena; Young Adult | 2021 |
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration.
Topics: Animals; Blood-Brain Barrier; Brain; Coenzyme A; Cyclization; Disease Models, Animal; Half-Life; Hepatocytes; Humans; Lipid Droplets; Mice; Mice, Inbred C57BL; Mice, Knockout; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Prodrugs; Structure-Activity Relationship | 2020 |
Targeting
Topics: Coenzyme A; Cysteine; Mycobacterium tuberculosis; Pantothenic Acid; Peptide Synthases | 2021 |
Turnover rate of coenzyme A in mouse brain and liver.
Topics: Acetyl Coenzyme A; Administration, Oral; Animals; Biotransformation; Brain; Coenzyme A; Female; Half-Life; Humans; Injections, Intraventricular; Liver; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Pantothenic Acid | 2021 |
The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cells, Cultured; Coenzyme A; Crystallization; Drosophila melanogaster; Enzyme Inhibitors; gamma-Aminobutyric Acid; Kinetics; Molecular Conformation; Pantothenic Acid; Peptide Synthases; Substrate Specificity | 2021 |
Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory.
Topics: Acoustic Stimulation; Amygdala; Animals; Coenzyme A; Conditioning, Classical; Electroshock; Fear; Freezing Reaction, Cataleptic; Glutathione; Hippocampus; Male; Memory; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Pantothenic Acid; Parietal Lobe; Stress Disorders, Post-Traumatic | 2021 |
Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii.
Topics: Animals; Biosynthetic Pathways; Cell Differentiation; Cell Membrane; Coenzyme A; Cytoplasm; Female; Life Cycle Stages; Mice; Pantothenic Acid; Parasites; Persistent Infection; Phosphotransferases (Alcohol Group Acceptor); Protein Multimerization; Toxoplasma; Toxoplasmosis | 2022 |
Immunostimulatory effects of vitamin B5 improve anticancer immunotherapy.
Topics: Animals; Coenzyme A; Gastrointestinal Microbiome; Humans; Immunologic Factors; Immunotherapy; Melanoma; Mice; Pantothenic Acid | 2022 |
PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Cell Proliferation; Coenzyme A; Cysteine; Lipid Metabolism; Mass Spectrometry; Metabolomics; Pantothenic Acid; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Signal Transduction | 2022 |
Generation and Validation of an Anti-Human PANK3 Mouse Monoclonal Antibody.
Topics: Animals; Antibodies, Monoclonal; Coenzyme A; Humans; Mice; Neoplasms; Pantothenic Acid; Precision Medicine; Protein Isoforms | 2022 |
Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation.
Topics: Animals; Coenzyme A; Encephalomyelitis, Autoimmune, Experimental; Humans; Pantothenic Acid; Protein Isoforms; Pyruvate Kinase; Th17 Cells | 2022 |
Vitamin B5, a coenzyme A precursor, rescues TANGO2 deficiency disease-associated defects in Drosophila and human cells.
Topics: Animals; Coenzyme A; Drosophila; Drosophila melanogaster; Humans; Pantothenic Acid; Phenotype | 2023 |
The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma.
Topics: Animals; CD8-Positive T-Lymphocytes; Coenzyme A; Humans; Mice; Pantothenic Acid; Sarcoma; Tumor Microenvironment | 2023 |