pantethine has been researched along with pantetheine in 147 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 82 (55.78) | 18.7374 |
1990's | 24 (16.33) | 18.2507 |
2000's | 9 (6.12) | 29.6817 |
2010's | 29 (19.73) | 24.3611 |
2020's | 3 (2.04) | 2.80 |
Authors | Studies |
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Hsu, JC; Inayama, I; Ohtani, S; Tanaka, K | 1 |
Kumerova, AO; Lipsberga, ZE; Shkestere, IIa; Utno, LIa | 1 |
Noacco, C; Taboga, C; Tonutti, L | 1 |
Hamano, T; Hiramatsu, N; Kishida, T; Natake, M | 1 |
Utno, LIa | 1 |
Girgensone, MIa; Shkesters, AP; Utno, LIa | 1 |
Alling, C; Ekman, R; Vécsei, L; Widerlöv, E | 1 |
Barrientos, A; Coronel, F; De Oleo, P; Macia, M; Naranjo, P; Tornero, F; Torrente, J | 1 |
Kumerova, AO; Silova, AA; Utno, LIa | 1 |
Vécsei, L; Widerlöv, E | 1 |
Jeitner, TM; Oliver, JR | 1 |
Lau-Cam, CA; Nagiel-Ostaszewski, I | 1 |
Binaghi, P; Bruschi, F; Cellina, G; Lo Cicero, G; Penotti, M; Porcaro, E | 1 |
Haldar, J; Miaskowski, C; Ong, GL | 1 |
Barbi, G; Bertieri, RS; Donati, C | 1 |
Alling, C; Heilig, M; Vécsei, L; Widerlöv, E | 1 |
Hiramatsu, N; Kishida, T; Natake, M | 1 |
Abucham, J; Bollinger-Gruber, J; Reichlin, S | 1 |
Lu, ZL | 1 |
Kobayashi, S | 1 |
Bollinger-Gruber, JA; Reichlin, S | 1 |
Chonan, N; Eto, M; Ishii, K; Watanabe, K | 1 |
Arsenio, L; Bodria, P; Bossi, S; Lateana, M; Strata, A | 1 |
Baccarini, S; Bassi, R; Sartori, MP; Sellini, M | 1 |
Arsenio, L; Bodria, P; Magnati, G; Strata, A; Trovato, R | 1 |
Balestreri, R; Bertolini, S; Cuzzolaro, S; Daga, A; Donati, C; Elicio, N; Marcenaro, A; Saturnino, M | 1 |
Cighetti, G; Del Puppo, M; Fiorica, E; Galli Kienle, M; Paroni, R | 1 |
Biffignandi, P | 1 |
Cighetti, G; Del Puppo, M; Galli Kienle, M; Paroni, R | 1 |
Hobara, N; Nagashima, H; Watanabe, A | 1 |
Hansen, RG; Wittwer, CT; Wyse, BW | 1 |
Campanari, JC; Di Rienzo, F; Forti, N; Giannini, SD; Ziliotto, EE | 1 |
Abbate, R; Gensini, GF; Matucci, M; Neri Serneri, GG; Paniccia, R; Prisco, D; Rogasi, PG | 1 |
Collado, CM; Hsu, JC; Ohtani, S; Tanaka, K | 1 |
Cappelletti, C; Cecchi, L; Innocenti, M; Leopardi, A; Tinacci, L | 1 |
Graves, CP; Hansen, RG; Jorgensen, E; Peterson, MA; Thoene, JG; Wilson, DE; Windham, CT; Wittwer, CT; Wyse, BW | 1 |
Cighetti, G; Del Puppo, M; Galli, G; Kienle, MG; Paroni, R | 1 |
Ishihara, M; Ogawa, H; Tawara, K; Tomikawa, M | 1 |
Komatsu, H; Satoh, M; Suzuki, M | 1 |
Chierchia, I; Cicerano, U; Mancini, M; Postiglione, A; Rubba, P | 1 |
Kameyama, M; Miyahara, T; Murai, A; Nishimura, N; Sako, Y; Tanaka, T | 2 |
Hayashi, H; Kamikawa, T; Kobayashi, A; Nagao, B; Nishiyama, T; Terada, H; Yamazaki, N | 1 |
Biffignandi, P; Fanini, A; Vignola, D | 1 |
Butler, JD; Gahl, WA; Thoene, JG; Wittwer, CT; Zatz, M | 1 |
Gensini, GF; Matucci, M; Neri Serneri, GG; Prisco, D; Rogasi, PG | 1 |
Thoene, JG | 1 |
Avogaro, P; Bon, GB; Cazzolato, G; Zago, S | 1 |
Canonaco, F; Sala, R | 1 |
Azuma, I; Iida, J; Nishimura, K; Ukei, S | 1 |
Calvi, E; Gentili, P; Manzardo, S; Picciòla, G; Ravenna, F; Riva, M | 1 |
Arsenio, L; Caronna, S; Lateana, M; Magnati, G; Strata, A; Zammarchi, G | 1 |
Chiti, D; Imperiale, A; Proietti, C | 1 |
Chiti, D; Ligas, B; Proietti, C | 1 |
Colombo, L; Craveri, A; Descovich, GC; Fragiacomo, C; Gaddi, A; Montanari, G; Noseda, G; Sirtori, CR | 1 |
Carrara, P; Franceschini, G; Galbussera, M; Lovati, MR; Matturri, L; Sirtori, CR | 1 |
Branca, D; Scutari, G; Siliprandi, N | 1 |
Kobayashi, M; Nagashima, H; Nakatsukasa, S; Watamaba, A; Yoshihara, T | 1 |
Kumagai, A; Matsuoka, N; Morisaki, N; Saito, Y | 1 |
Kumagai, A; Matsuoka, N; Morisaki, N; Saito, Y; Sasaki, N; Shirai, K | 1 |
Jonas, AJ; Pellett, OL; Schneider, JA; Smith, ML; Thoene, JG | 1 |
Kita, M; Noma, A; Okamiya, T | 1 |
Butler, JD; Zatz, M | 2 |
Manna, H; Suga, T; Watanabe, T | 1 |
Minami, M; Saito, H; Yasuda, H | 1 |
Abiko, Y; Kameda, KY; Nakayasu, T; Tawara, K; Tomikawa, M | 1 |
Abiko, Y; Shibano, T | 1 |
Farina, R; Lovati, MR; Raucci, G; Sirtori, CR | 1 |
Harmony, JA; Jackson, RL; Ranganathan, S | 1 |
Arimori, S; Hiramatsu, K; Nozaki, H | 1 |
Fukuhara, C; Horiuchi, I; Kajiyama, G; Kawamoto, T; Miyoshi, A; Nakagawa, M | 1 |
Koga, Y; Komori, T; Murata, T; Oniki, H; Tsugi, H | 1 |
Nakayama, S; Negishi, K; Sakamoto, K | 1 |
Kimura, Y; Koga, Y; Komoda, T; Murata, T; Nakamura, S; Oniki, H; Yamashita, Y | 1 |
Davis, PS; Sharma, DC; Sharma, PK | 1 |
Clark, JI; Hiraoka, T | 1 |
Moiseenok, AG; Rakowska, M; Slyshenkov, VS; Wojtczak, L | 1 |
Clark, JI; Hiraoka, T; LI, XY; Thurston, GM | 1 |
Clark, JI; Livesey, JC; Steele, JE | 1 |
Clark, JI; Huang, QL | 1 |
Benedek, GB; Friberg, G; Ogun, O; Pande, J | 1 |
Fisher, DH; Szulc, ME | 1 |
Clark, JI; David, LL; Hiraoka, T; Matsushima, H | 1 |
Webster, MJ | 1 |
Cole, L; Congdon, NT; Duncan, DT; Fisher, DT; Hazelwood, DT; McNaughton, C; Pham, T; Rieger, KT; Sanchez, AT; Urist, JT; Vitale, ST; West, ST | 1 |
McCarty, MF | 1 |
Hata, Y; Hirose, N; Nakajima, K; Osono, Y | 1 |
Harding, JJ | 1 |
BROWN, GM; SNELL, EE | 2 |
GROB, EC; GRUNDBACHER, V; SCHOPPER, WH | 1 |
ANNONI, G | 1 |
AMBANELLI, U; SALVI, G | 1 |
MAINOLI, S; NICROSINI, F; PICCINELLI, O | 1 |
EARL, JM; STADTMAN, ER; VAGELOS, PR | 1 |
RUGGIERI, R | 1 |
CURIONI, GB | 1 |
BALESTRERI, R; CORREALE, L; LAMEDICA, G | 1 |
DI TOMMASI, M; NOFERI, A; SPADA, U; STARACE, G | 2 |
REEVES, RE | 1 |
KOHSAKA, M | 1 |
HUHTANEN, CN | 1 |
BROWN, GM; SNELL, EE; WARD, GB | 1 |
CRAIG, JA; SNELL, EE | 1 |
GIBBONS, AJ; GOVIER, WM | 1 |
Alejandro, S; Gonzalez-Guzman, M; Graham, IA; Larson, TR; Rodriguez, PL; Rubio, S; Serrano, R | 1 |
Keenan, JM; Pins, JJ | 1 |
Abou-Hamdan, M; Coltel, N; Cornille, E; de Reggi, M; Gharib, B; Grau, GE; Penet, MF | 1 |
Ishida, Y; Nyunt, AK; Shimada, S; Yu, Y | 1 |
Horváth, Z; Vécsei, L | 1 |
Hayflick, S; Kayser, O; Muntendam, R; Rana, A; Reijngoud, DJ; Seinen, E; Sibon, OC; Siudeja, K; Srinivasan, B; van der Want, JJ | 1 |
Abou-Hamdan, M; Cornille, E; de Reggi, M; Gharib, B; Khrestchatisky, M; Nieoullon, A | 1 |
Balibar, CJ; Hollis-Symynkywicz, MF; Tao, J | 1 |
Azumano, I; Evans, M; Kamiya, T; Napolitano, J; Rumberger, JA | 1 |
Abe, T; Itoh, H; Nishimura, F; Sato, Y; Suzuki, Y; Takeyama, M | 1 |
de Jong, J; Hayflick, S; Jackowski, S; Nollen, EA; Rana, A; Sanford, L; Sibon, OC; Siudeja, K; Srinivasan, B; Xu, L | 1 |
Houston, M | 1 |
Clark, JI | 1 |
Burkart, MD; Chapman, E; Kang, M; Kelleher, NL; La Clair, JJ; Ntai, I; Rothmann, M; Villa, R | 1 |
Fukuwatari, T; Kaneko, M; Shibata, K | 1 |
Sandberg, M; Weber, SG; Wu, J | 1 |
Brunetti, D; d'Amati, G; Dusi, S; Fagiolari, G; Fugnanesi, V; Giordano, C; Lamperti, C; Marchet, S; Moggio, M; Morbin, M; Sibon, O; Tiranti, V | 1 |
Németh, AH | 1 |
Azumano, I; Citrolo, D; Evans, M; Kamiya, T; Napolitano, JJ; Rumberger, JA | 1 |
Aprile, S; Canavesi, R; Grosa, G; Varese, E | 1 |
Berger, W; Chumak, V; Gurinovich, V; Heffeter, P; Lehka, L; Moiseenok, A; Omelyanchik, S; Panchuk, R; Skorokhyd, N; Stoika, R | 1 |
Avetisov, SÉ; Muranov, KO; Ostrovskiĭ, MA; Polianskiĭ, NB; Polunin, GS; Sheremet, NL | 1 |
Bebawy, M; Luk, F; Roseblade, A; Ung, A | 1 |
Acar, N; Bretillon, L; de Reggi, M; Gharib, B; Khrestchatisky, M; Molino, Y; van Gijsel-Bonnello, M | 1 |
Batteux, F; Chéreau, C; Chimini, G; Galland, F; Guilpain, P; Kavian, N; Lemaréchal, H; Marut, W; Naquet, P; Nicco, C; Servettaz, A; Weill, B | 1 |
Horváth, Z; Tuka, B; Vécsei, L | 1 |
Chumak, VV; Gurinovich, VA; Kozak, YS; Lehka, LV; Moiseenok, AG; Omelyanchik, SN; Panchuk, RR; Skorokhyd, NR; Stoika, RS | 1 |
Kozak, YS; Lehka, LV; Moiseenok, AG; Panchuk, RR; Skorokhyd, NR; Stoika, RS | 1 |
Baranger, K; Benech, P; de Reggi, M; Gharib, B; Khrestchatisky, M; Rivera, S; van Gijsel-Bonnello, M | 1 |
Huang, F; Sapkota, K | 1 |
Abou-Hamdan, M; Bajenoff, M; de Reggi, M; Gharib, B; Julia, V | 1 |
Abudi, S; Alhaddad, B; Anikster, Y; Avivi, C; Barel, O; Barshack, I; Berutti, R; Braunisch, M; Brundel, BJJM; Dubnov-Raz, G; Eyal, E; Grigat, M; Grzeschik, NA; Haack, TB; Haas, D; Hoffmann, GF; Iuso, A; Kanon, B; Kumbar, M; Marek-Yagel, D; Mastantuono, E; Meitinger, T; Messias, AC; Okun, JG; Perles, Z; Pode-Shakked, B; Prokisch, H; Rubinshtein, M; Salem, Y; Schüller, HJ; Schwarzmayr, T; Sibon, OCM; Strom, TM; Terrile, C; Tirosh, T; Vardi, A; Volkov, A; Wiersma, M | 1 |
Baranger, K; Benech, P; Carpentier, W; De Reggi, M; Gharib, B; Khrestchatisky, M; Rivera, S; Stephan, D; van Gijsel-Bonnello, M | 1 |
Chang, X; Jiang, Y; Wang, J; Wu, Y; Yao, B; Zhang, J | 1 |
Cseh, EK; Tóth, F; Vécsei, L | 1 |
Chen, Y; He, L; Jiang, H; Lin, M; Liu, H; Tang, E; Zhao, Y | 1 |
8 review(s) available for pantethine and pantetheine
Article | Year |
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Preclinical and clinical studies with cysteamine and pantethine related to the central nervous system.
Topics: Alcoholism; Animals; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Cysteamine; Humans; Pantetheine; Parkinson Disease | 1990 |
[Atherosclerosis and prostaglandins: new biochemical frontiers of a more rational therapy].
Topics: Arteriosclerosis; Cholesterol; Diet; Epoprostenol; Female; Humans; Lipoproteins; Male; Pantetheine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Risk; Thromboxanes; Triglycerides | 1987 |
Can drugs or micronutrients prevent cataract?
Topics: Aldehyde Reductase; Aspirin; Cataract; Clinical Trials as Topic; Drug Design; Estrogens; Glutathione; Humans; Pantetheine | 2001 |
Dietary and nutraceutical options for managing the hypertriglyceridemic patient.
Topics: Dietary Carbohydrates; Energy Intake; Evidence-Based Medicine; Exercise; Fasting; Fish Oils; Humans; Hypertriglyceridemia; Metabolic Syndrome; Niacin; Obesity; Pantetheine; Practice Guidelines as Topic; Risk Factors; Risk Reduction Behavior; Severity of Illness Index; Triglycerides; Weight Loss | 2006 |
Current medical aspects of pantethine.
Topics: Acetylcholine; Animals; Antioxidants; Atherosclerosis; Blood Platelets; Cataract; Central Nervous System; Coenzyme A; Cystine; Cystinosis; Dietary Carbohydrates; Fatty Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Oxidation-Reduction; Pantetheine; Pantothenic Acid; Pyruvates | 2009 |
Pantethine. Monograph.
Topics: Animals; Antioxidants; Apolipoproteins B; Cataract; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Lipid Peroxides; Pantetheine | 2010 |
OLD AND NEW NEUROENDOCRINE MOLECULES: SOMATOSTATIN, CYSTEAMINE, PANTETHINE AND KYNURENINE.
Topics: Animals; Cysteamine; History, 20th Century; Humans; Kynurenine; Neuroendocrinology; Neurosecretory Systems; Pantetheine; Rats; Signal Transduction; Somatostatin; Tryptophan | 2014 |
Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid.
Topics: Animals; Antioxidants; Humans; Kynurenic Acid; Metabolic Networks and Pathways; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Pantetheine; Thioctic Acid | 2021 |
12 trial(s) available for pantethine and pantetheine
Article | Year |
---|---|
[A double-blind clinical trial--the effects of pantethine on serum lipids in patients with hyperlipidemia].
Topics: Adult; Aged; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperlipidemias; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1989 |
[Effects of pantethine on blood lipids].
Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Female; Humans; Lipids; Male; Middle Aged; Pantetheine; Risk; Sulfhydryl Compounds; Triglycerides | 1986 |
Effect of oral treatment with pantethine on platelet and plasma phospholipids in IIa hyperlipoproteinemia.
Topics: Administration, Oral; Adult; Aged; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Phospholipids; Sphingomyelins; Sulfhydryl Compounds | 1987 |
Pantethine versus fenofibrate in the treatment of type II hyperlipoproteinemia.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Male; Pantetheine; Propionates; Random Allocation; Sulfhydryl Compounds | 1985 |
[Clinical study of the lipotropic activity of the preparation Fosfolip].
Topics: Adult; Aged; Arteriosclerosis; Choline; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hyperlipidemias; Lipids; Liver Diseases; Male; Middle Aged; Pantetheine; Phosphorylcholine; Sulfhydryl Compounds | 1983 |
Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia.
Topics: Adult; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Lipoproteins, HDL; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1984 |
Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives.
Topics: Adult; Bicycling; Blood Glucose; Double-Blind Method; Exercise; Exercise Test; Fatty Acids, Nonesterified; Heart Rate; Humans; Lactic Acid; Male; Oxygen Consumption; Pantetheine; Pantothenic Acid; Pulmonary Gas Exchange; Thiamine | 1998 |
The effects of pantethine on fatty liver and fat distribution.
Topics: Abdomen; Aged; Case-Control Studies; Fatty Liver; Female; Humans; Liver; Male; Middle Aged; Pantetheine; Tomography, X-Ray Computed | 2000 |
Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled invest
Topics: Adult; Apolipoproteins B; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Diet; Dietary Supplements; Double-Blind Method; Female; Health Promotion; Humans; Life Style; Male; Middle Aged; North America; Pantetheine; Risk; Vitamin B Complex | 2011 |
Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.
Topics: Adult; Calcitonin Gene-Related Peptide; Drug Administration Schedule; Drug Evaluation, Preclinical; Fursultiamin; Gastrointestinal Tract; Humans; Male; Molecular Targeted Therapy; Motilin; Pantetheine; Substance P; Vasoactive Intestinal Peptide; Vitamin B Complex | 2011 |
Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation.
Topics: Adult; Anticholesteremic Agents; Biomarkers; Cholesterol; Cholesterol, LDL; Combined Modality Therapy; Coronary Disease; Female; Florida; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Ontario; Pantetheine; Patient Selection; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2014 |
Pilot trial on the efficacy and safety of pantethine in children with pantothenate kinase-associated neurodegeneration: a single-arm, open-label study.
Topics: Child; Female; Humans; Male; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Pilot Projects; Quality of Life; Treatment Outcome | 2020 |
127 other study(ies) available for pantethine and pantetheine
Article | Year |
---|---|
Effects of pantethine on lipogenesis and CO2 production in the isolated hepatocytes of the chick (Gallus domesticus).
Topics: Animals; Body Weight; Carbon Dioxide; Cell Survival; Cells, Cultured; Chickens; Fatty Acids; Lipids; Liver; Male; Organ Size; Oxidation-Reduction; Pantetheine | 1992 |
[Study of pantothenic acid derivatives as cardiac protectors in a model of experimental ischemia and reperfusion of the isolated heart].
Topics: Adenosine Triphosphate; Animals; Heart; In Vitro Techniques; Lactates; Lipid Peroxidation; Male; Myocardium; Pantetheine; Pantothenic Acid; Phosphocreatine; Rats; Rats, Wistar; Reperfusion Injury | 1992 |
[Comparison of the efficacy of pantethine, acipimox, and bezafibrate on plasma lipids and index of cardiovascular risk in diabetics with dyslipidemia].
Topics: Bezafibrate; Cardiovascular Diseases; Diabetes Complications; Humans; Hyperlipidemias; Hypolipidemic Agents; Pantetheine; Pyrazines; Risk Factors | 1991 |
Effects of dietary pantethine levels on contents of fatty acids and thiobarbituric acid reactive substances in the liver of rats orally administered varying amounts of autoxidized linoleate.
Topics: Administration, Oral; Animals; Body Weight; Chromatography, Gas; Fatty Acids; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Liver; Male; Malondialdehyde; Pantetheine; Rats; Rats, Inbred Strains; Thiobarbiturates | 1991 |
[Effects of pantethine on metabolism in myocardial mitochondria under the conditions of deep hypothermia].
Topics: Animals; Coenzyme A; Cytosol; Hypothermia; Malate Dehydrogenase; Male; Mitochondria, Heart; Oxidoreductases; Pantetheine; Rats; Rats, Inbred Strains | 1991 |
[Regulation of superoxide dismutase activity during deep hypothermia by simultaneous administration of water and lipid soluble antioxidants].
Topics: Animals; Catecholamines; Hypothermia; Male; Myocardium; Pantetheine; Rats; Rats, Inbred Strains; Vitamin E | 1991 |
Dose- and time-response effects of pantethine on open-field behavior, and on central neurotransmission in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Exploratory Behavior; Hypothalamus; Male; Neurotransmitter Agents; Norepinephrine; Pantetheine; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Sulfhydryl Compounds; Time Factors | 1990 |
Treatment of hyperlipemia in diabetic patients on dialysis with a physiological substance.
Topics: Cholesterol; Cholesterol, VLDL; Diabetic Nephropathies; Evaluation Studies as Topic; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Male; Middle Aged; Pantetheine; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Triglycerides | 1991 |
[Effect of pantethine on post-heparin lipolytic activity and lipid peroxidation in the myocardium].
Topics: Animals; Antioxidants; Enzyme Activation; Heparin; Hypolipidemic Agents; Lipid Metabolism; Lipid Peroxidation; Lipids; Lipoprotein Lipase; Male; Myocardium; Pantetheine; Rats; Rats, Inbred Strains | 1991 |
The depletion of plasma prolactin by pantethine in oestrogen-primed hyperprolactinaemic rats.
Topics: Administration, Oral; Animals; Cysteamine; Estradiol; Hyperprolactinemia; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Male; Pantetheine; Pituitary Gland; Prolactin; Rats; Sulfhydryl Compounds | 1990 |
Protection by pantethine, pantothenic acid and cystamine against carbon tetrachloride-induced hepatotoxicity in the rat.
Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholesterol; Cystamine; Lipid Metabolism; Liver; Male; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Triglycerides | 1990 |
[Evaluation of the cholesterol-lowering effectiveness of pantethine in women in perimenopausal age].
Topics: Cholesterol, HDL; Cholesterol, LDL; Drug Evaluation; Female; Humans; Hypercholesterolemia; Menopause; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1990 |
Changes in oxytocin and vasopressin content in posterior pituitary and hypothalamus following pantethine treatment.
Topics: Analysis of Variance; Animals; Hypothalamus; Male; Oxytocin; Pantetheine; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasopressins | 1990 |
[Pantethine, diabetes mellitus and atherosclerosis. Clinical study of 1045 patients].
Topics: Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hyperlipoproteinemias; Male; Middle Aged; Pantetheine; Product Surveillance, Postmarketing; Sulfhydryl Compounds | 1989 |
Effects of cysteamine and pantethine on open-field behavior, hypothalamic catecholamine concentrations, and somatostatin-induced barrel rotation in rats.
Topics: Animals; Cysteamine; Dose-Response Relationship, Drug; Drug Interactions; Hypothalamus; Male; Motor Activity; Pantetheine; Rats; Rats, Inbred Strains; Somatostatin; Stereotyped Behavior; Sulfhydryl Compounds | 1989 |
Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate.
Topics: Animals; Cytochrome P-450 Enzyme System; Cytochromes b5; Diet; Dose-Response Relationship, Drug; Electron Transport; Growth; Linoleic Acid; Linoleic Acids; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1989 |
Pantethine, a somatostatin depleting agent, increases food intake in rats.
Topics: Animals; Blood Glucose; Circadian Rhythm; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Food Deprivation; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1989 |
Investigation of the roles of the substances in serum lipids and their constitutive fatty acids in chronic urticaria.
Topics: Adult; Ascorbic Acid; Chronic Disease; Fatty Acids; Female; Glutathione; Humans; Lipids; Male; Middle Aged; Pantetheine; Urticaria | 1989 |
Pantethine, a cysteamine precursor, depletes immunoreactive somatostatin and prolactin in the rat.
Topics: Animals; Cerebral Cortex; Duodenum; Gastric Mucosa; Hypothalamus; Intestinal Mucosa; Kinetics; Male; Pancreas; Pantetheine; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Sulfhydryl Compounds; Tissue Distribution | 1985 |
Lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus.
Topics: Adult; Aged; beta-Thromboglobulin; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds | 1987 |
[Clinical use of pantethine by parenteral route in the treatment of hyperlipidemia].
Topics: Cholesterol; Female; Humans; Hyperlipidemias; Infusions, Parenteral; Lipoproteins; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds | 1987 |
[Various hormonal parameters (ACTH, cortisol, somatotropic hormone and prolactin) following administration of a single high dose of pantethine in healthy subjects].
Topics: Adrenocorticotropic Hormone; Adult; Female; Growth Hormone; Humans; Hydrocortisone; Male; Pantetheine; Pituitary Gland, Anterior; Prolactin; Sulfhydryl Compounds | 1987 |
Effectiveness of long-term treatment with pantethine in patients with dyslipidemia.
Topics: Cholesterol; Female; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Long-Term Care; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1986 |
Lipoprotein changes induced by pantethine in hyperlipoproteinemic patients: adults and children.
Topics: Adolescent; Adult; Aged; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Child; Cholesterol; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1986 |
Pantethine inhibits cholesterol and fatty acid syntheses and stimulates carbon dioxide formation in isolated rat hepatocytes.
Topics: Animals; Carbon Dioxide; Cholesterol; Fatty Acids; In Vitro Techniques; Lipid Metabolism; Liver; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1987 |
Modulation of HMG-CoA reductase activity by pantetheine/pantethine.
Topics: Animals; Enzyme Activation; Glutathione; Hydroxymethylglutaryl CoA Reductases; Kinetics; Male; Microsomes, Liver; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1988 |
Activation and inhibition of yeast aldehyde dehydrogenase activity by pantethine and its metabolites.
Topics: Acetyl Coenzyme A; Aldehyde Dehydrogenase; Coenzyme A; Cysteamine; Enzyme Activation; Pantetheine; Pantothenic Acid; Saccharomyces cerevisiae; Sulfhydryl Compounds; Taurine | 1986 |
Enzymatic hydrolysis of pantetheine.
Topics: Amidohydrolases; Animals; Carbon Radioisotopes; Chromatography, Paper; Electrophoresis, Polyacrylamide Gel; GPI-Linked Proteins; Indicators and Reagents; Kidney; Kinetics; Male; Pantetheine; Radioisotope Dilution Technique; Rats; Sulfhydryl Compounds; Swine; Tissue Distribution | 1986 |
Effects of pantethine supplementation to diets with different energy cereals on hepatic lipogenesis of laying hens.
Topics: Animal Nutritional Physiological Phenomena; Animals; Chickens; Edible Grain; Female; Lipid Metabolism; Liver; Oviposition; Pantetheine; Sulfhydryl Compounds | 1987 |
[Thrombocytopenic purpura during treatment with pantethine].
Topics: Aged; Female; Humans; Pantetheine; Purpura, Thrombocytopenic; Sulfhydryl Compounds | 1987 |
Pantethine lipomodulation: evidence for cysteamine mediation in vitro and in vivo.
Topics: Animals; Cells, Cultured; Coenzyme A; Cysteamine; Diabetes Mellitus, Experimental; Humans; Hydrolysis; Hypercholesterolemia; Lipid Metabolism; Male; Pantetheine; Rabbits; Rats; Sulfhydryl Compounds | 1987 |
Effects of pantethine on cholesterol synthesis from mevalonate in isolated rat hepatocytes.
Topics: Animals; Carbon Radioisotopes; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Male; Mevalonic Acid; Pantetheine; Rats; Rats, Inbred Strains; Squalene; Sterol O-Acyltransferase; Sulfhydryl Compounds | 1986 |
Effect of probucol, pantethine and their combinations on serum lipoprotein metabolism and on the incidence of atheromatous lesions in the rabbit.
Topics: Animals; Apolipoproteins; Arteriosclerosis; Cholesterol, HDL; Drug Synergism; Lipoproteins; Male; Pantetheine; Phenols; Probucol; Rabbits; Sulfhydryl Compounds | 1986 |
[Studies on percutaneous absorption of pantethine in guinea pigs].
Topics: Animals; Autoradiography; Guinea Pigs; Male; Pantetheine; Skin Absorption; Sulfhydryl Compounds | 1986 |
The effects of pantethine on lipid and lipoprotein abnormalities in survivors of cerebral infarction.
Topics: Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Cerebral Infarction; Cholesterol; Humans; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Pantetheine; Phospholipids; Sulfhydryl Compounds; Triglycerides | 1985 |
Effects of pantethine on action potential of canine papillary muscle during hypoxic perfusion.
Topics: Action Potentials; Animals; Dogs; Electrophysiology; In Vitro Techniques; Membrane Potentials; Microelectrodes; Oxygen; Pantetheine; Papillary Muscles; Perfusion; Refractory Period, Electrophysiological; Sulfhydryl Compounds | 1985 |
[Effects of D(+)-bis-(N-pantothenyl-amidoethyl)-disulphur on the blood lipid profile and apoproteins A and B levels].
Topics: Adult; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Female; Humans; Lipids; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides | 1985 |
Metabolism of pantethine in cystinosis.
Topics: Adolescent; Amidohydrolases; Animals; Child; Cysteamine; Cystine; Cystinosis; Diarrhea; Female; GPI-Linked Proteins; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Leukocytes; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1985 |
Changes in fatty acid composition of the single platelet phospholipids induced by pantethine treatment.
Topics: Administration, Oral; Adult; Aged; Blood Platelets; Cholesterol; Cholesterol, HDL; Chromatography, Gas; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sulfhydryl Compounds; Triglycerides | 1985 |
Therapy of cystinosis.
Topics: Cysteamine; Cystinosis; Humans; Orphan Drug Production; Pantetheine | 1985 |
Effects of pantethine on in-vitro peroxidation of low density lipoproteins.
Topics: Antioxidants; Apolipoproteins B; Dialysis; Glutathione; Humans; In Vitro Techniques; Lipid Peroxides; Lipoproteins, LDL; Male; Malondialdehyde; Molecular Weight; Pantetheine; Sulfhydryl Compounds | 1985 |
[Therapeutic use of a combination containing calcium, vitamins, pantethine and carnitine in convalescence states in childhood].
Topics: Calcium; Carnitine; Child; Child, Preschool; Convalescence; Drug Combinations; Female; Humans; Infant; Male; Pantetheine; Sulfhydryl Compounds; Vitamins | 1985 |
Macrophage activation with pantethine and pantetheine-4'-phosphate.
Topics: Animals; Cells, Cultured; Cytotoxicity, Immunologic; Female; Kinetics; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Pantetheine; Structure-Activity Relationship; Sulfhydryl Compounds | 1985 |
Pantetheine and pantethine esters with hypolipidemic nicotinic acid derivatives.
Topics: Animals; Chemical Phenomena; Chemistry; Fatty Acids, Nonesterified; Hypolipidemic Agents; Male; Nicotinic Acids; Pantetheine; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Triglycerides | 1985 |
[Hyperlipidemia, diabetes and atherosclerosis: efficacy of treatment with pantethine].
Topics: Adolescent; Adult; Aged; Apolipoproteins; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Complications; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemias; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds | 1984 |
[Treatment of chronic hepatopathies with phosphorylcholine and pantethine].
Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Female; Humans; Liver Diseases; Male; Middle Aged; Pantetheine; Phosphorylcholine; Sulfhydryl Compounds | 1984 |
Pantethine reduces plasma cholesterol and the severity of arterial lesions in experimental hypercholesterolemic rabbits.
Topics: Animals; Aorta, Abdominal; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Cholesterol, Dietary; Cholesterol, HDL; Coronary Vessels; Hypercholesterolemia; Isoelectric Focusing; Lipoproteins, HDL; Male; Pantetheine; Rabbits; Sulfhydryl Compounds | 1984 |
Pantethine and pantothenate effect on the CoA content of rat liver.
Topics: Animals; Coenzyme A; Cysteine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1984 |
[Effect of oral pantethine administration on blood acetaldehyde levels following alcohol ingestion].
Topics: Acetaldehyde; Administration, Oral; Adult; Alcohol Drinking; Humans; Male; Pantetheine; Sulfhydryl Compounds | 1984 |
Effects of pantethine and its metabolites on fatty acid oxidation in rat liver mitochondria.
Topics: Acyl Coenzyme A; Animals; Carnitine Acyltransferases; Coenzyme A Ligases; Fatty Acids; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sulfhydryl Compounds | 1983 |
Effect of pantethine on fatty acid oxidation in microvessels of rat brain.
Topics: Animals; Brain; Cerebral Hemorrhage; Fatty Acids; Hypertension; In Vitro Techniques; Microcirculation; Pantetheine; Rats; Sulfhydryl Compounds | 1983 |
Renal cell culture using autopsy material from children with cystinosis.
Topics: Autopsy; Cells, Cultured; Child, Preschool; Cysteamine; Cystine; Cystinosis; Fibroblasts; Humans; Kidney; Male; Pantetheine | 1984 |
Effect of pantethine on post-heparin plasma lipolytic activities and adipose tissue lipoprotein lipase in rats.
Topics: Adipose Tissue; Animals; Body Weight; Chromatography, Agarose; Epididymis; Hyperlipidemias; Lipids; Lipoprotein Lipase; Liver; Male; Organ Size; Pantetheine; Rats; Rats, Inbred Strains; Sepharose; Subcellular Fractions; Sulfhydryl Compounds | 1984 |
Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine-cysteine mixed disulfide.
Topics: Cells, Cultured; Child; Cystamine; Cystine; Cystinosis; Fibroblasts; Humans; Kinetics; Pantetheine; Skin; Sulfhydryl Compounds | 1984 |
Effects of some hypolipidemic drugs on biochemical values and on hepatic peroxisomal enzymes of normolipemic rat.
Topics: Animals; Carnitine O-Acetyltransferase; Cyclohexanols; Hypolipidemic Agents; Liver; Lovastatin; Microbodies; Naphthalenes; Nicotinic Acids; Organoids; Pantetheine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Riboflavin | 1981 |
Pantethine depletes cystinotic fibroblasts of cystine.
Topics: Cells, Cultured; Cystamine; Cystine; Cystinosis; Dose-Response Relationship, Drug; Fibroblasts; Humans; Pantetheine; Sulfhydryl Compounds | 1983 |
Positive inotropic and negative chronotropic effect of pantethine on isolated cardiac muscle of guinea-pigs.
Topics: Animals; Depression, Chemical; Guinea Pigs; Heart Atria; Heart Rate; Myocardial Contraction; Pantetheine; Stimulation, Chemical; Sulfhydryl Compounds | 1983 |
Effect of pantethine on lipoprotein profiles and HDL subfractions in experimentally hypercholesterolemic rabbits.
Topics: Animals; Cholesterol, Dietary; Hypercholesterolemia; Lipoproteins; Lipoproteins, HDL; Male; Pantetheine; Rabbits; Sulfhydryl Compounds | 1982 |
Effect of pantethine on myocardial pH reduced by partial occlusion of the coronary artery in dogs with special reference to the myocardial levels of adenosine triphosphate, creatine phosphate, and lactate.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Dogs; Female; Hemodynamics; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Pantetheine; Phosphocreatine; Sulfhydryl Compounds; Time Factors | 1982 |
Effects of pantethine on different models of experimental hyperlipidemia in rodents: a comparison with clofibrate.
Topics: Animals; Clofibrate; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, HDL; Male; Pantetheine; Rats; Sulfhydryl Compounds | 1982 |
Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts.
Topics: Acetates; Cholesterol; Depression, Chemical; DNA; Fatty Acids; Fibroblasts; Humans; Lanosterol; Mevalonic Acid; Pantetheine; Protein Biosynthesis; Skin; Sulfhydryl Compounds | 1982 |
[Effect of pantethine on the lipoprotein abnormalities in survivors of cerebral infarction (author's transl)].
Topics: Cerebral Infarction; Cholesterol; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Pantetheine; Sulfhydryl Compounds | 1980 |
Influence of pantethine on platelet volume, microviscosity, lipid composition and functions in diabetes mellitus with hyperlipidemia.
Topics: Blood Platelets; Blood Viscosity; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperglycemia; Lipids; Male; Pantetheine; Platelet Adhesiveness; Platelet Aggregation; Sulfhydryl Compounds | 1981 |
The effect of pantethine, a precursor of coenzyme A, on bile acids and lipids in rats fed with a cholesterol diet.
Topics: Animals; Bile Acids and Salts; Cholesterol, Dietary; Female; Lipid Metabolism; Lipids; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1981 |
[Study of enhancement of LCAT activity (author's transl)].
Topics: Adult; Arteriosclerosis; Drug Therapy, Combination; Humans; Kidney Diseases; Male; Pantetheine; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines | 1980 |
[Effects of soysterol, pantethine and dl-alpha-tocopheryl nicotinate on hyperlipemia in rats (author's transl)].
Topics: Animals; Body Weight; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Nicotinic Acids; Organ Size; Pantetheine; Phytosterols; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vitamin E | 1981 |
[Relationship between ADCC effector cells and the combination therapy of pantethine and lecithin--a proposal for management of patients with HBsAg carrier state (author's transl)].
Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Carrier State; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Sulfhydryl Compounds | 1981 |
Studies in search of modifiers of the toxicity of mercurials and speculations on its biochemical mechanism.
Topics: Animals; Coenzyme A; Cysteine; Glutathione; Goldfish; Mercury; Methylmercury Compounds; Pantetheine | 1981 |
Inhibition of lens opacification during the early stages of cataract formation.
Topics: Animals; Animals, Newborn; Cataract; Disease Models, Animal; Female; Injections, Subcutaneous; Lens, Crystalline; Male; Pantetheine; Rats; Rats, Sprague-Dawley; Sodium Selenite; Time Factors | 1995 |
Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Coenzyme A; Fatty Acids; Female; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Mice; Palmitic Acid; Palmitic Acids; Pantetheine; Pantothenic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Effect of selected anti-cataract agents on opacification in the selenite cataract model.
Topics: Animals; Antioxidants; Cataract; Chelating Agents; Disulfides; Pantetheine; Phosphates; Rats; Rats, Sprague-Dawley; Sodium Selenite; Temperature; Tissue Extracts | 1996 |
Delay or inhibition of rat lens opacification using pantethine and WR-77913.
Topics: Amifostine; Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Pantetheine; Protein Denaturation; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Sodium Selenite; Streptozocin | 1996 |
Modulation of the chaperone-like activity of bovine alpha-crystallin.
Topics: Alcohol Dehydrogenase; Animals; Cattle; Crystallins; Glutathione; Kinetics; Molecular Chaperones; Pantetheine; Protein Denaturation; Time Factors | 1996 |
Pantethine inhibits the formation of high-Tc protein aggregates in gamma B crystallin solutions.
Topics: Animals; Animals, Newborn; Biopolymers; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Hydrogen-Ion Concentration; Lens, Crystalline; Pantetheine | 1996 |
Reduction of pantethine in rabbit ocular lens homogenate.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Lens, Crystalline; Oxidation-Reduction; Pantetheine; Rabbits | 1997 |
Loss of cytoskeletal proteins and lens cell opacification in the selenite cataract model.
Topics: Actins; Animals; Blotting, Western; Cataract; Crystallins; Cytoskeletal Proteins; Disease Progression; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Pantetheine; Rats; Rats, Sprague-Dawley; Sodium Selenite; Spectrin; Tubulin; Vimentin | 1997 |
Pantethine.
Topics: Humans; Pantetheine | 1998 |
The effect of pantethine and ultraviolet-B radiation on the development of lenticular opacity in the emory mouse.
Topics: Animals; Cataract; Cysteamine; Disease Models, Animal; Disease Progression; Female; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Pantetheine; Ultraviolet Rays | 2000 |
Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine.
Topics: Acetyl-CoA Carboxylase; Animals; Cholesterol; Cystamine; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Liver; Models, Biological; Obesity; Pantetheine; Triglycerides | 2001 |
The relationship of pantethine to naturally occurring forms of the Lactobacillus bulgaricus factor.
Topics: Lactobacillus; Pantetheine; Pantothenic Acid; Sulfhydryl Compounds | 1952 |
Pantethine and related forms of the Lactobacillus bulgaricus factor (LBF).
Topics: Lactobacillus; Pantetheine; Pantothenic Acid | 1953 |
[Effect of pantothenic acid, pantethine and phosphorylated pantethine on carotene formation in Mucor hiemalis].
Topics: Carotenoids; Fungi; Lipogenesis; Mucor; Pantetheine; Pantothenic Acid; Pigments, Biological | 1954 |
[Pantethine].
Topics: Pantetheine; Pantothenic Acid | 1955 |
[Initial clinical experiments with pantethine].
Topics: Humans; Pantetheine; Pantothenic Acid | 1955 |
[Effect of pantethine on Co60 distribution].
Topics: Cobalt; Pantetheine; Pantothenic Acid; Sulfides | 1956 |
[Lipotropic & liver protective effect of pantethine in experimental liver diseases induced by Handler diet & carbon tetrachloride].
Topics: Carbon Tetrachloride; Diet; Lipotropic Agents; Liver Diseases; Pantetheine; Pantothenic Acid; Sulfides | 1957 |
Propionic acid metabolism. II. Enzymatic synthesis of lactyl pantethine.
Topics: Lactates; Pantetheine; Pantothenic Acid; Propionates; Pseudomonas | 1959 |
[Determination of pantethine in the presence of pantothenic acid].
Topics: Health Services; Pantetheine; Pantothenic Acid | 1961 |
[The action of pantethine on the take of the homoplastic bone grafts].
Topics: Amines; Bone Transplantation; Humans; Pantetheine; Pantothenic Acid | 1959 |
[In vitro effect of pantethine on the secretion of 21-C-corticosteroids by the ox adrenal].
Topics: Adrenal Cortex Hormones; Glucocorticoids; In Vitro Techniques; Pantetheine; Pantothenic Acid; Pregnadienes | 1962 |
[Histochemical aspects of the rat lung after treatment with prednisone and prednisone-pantethine].
Topics: Animals; Lung Diseases; Pantetheine; Pantothenic Acid; Prednisone; Rats | 1963 |
[Inhibition by pantethine of pulmonary hemorrhagic manifestations caused by prednisone. Experimental research in the rat].
Topics: Animals; Hemorrhage; Lung Diseases; Pantetheine; Pantothenic Acid; Prednisone; Rats | 1963 |
PANTETHINE-REQUIRING BACTEROIDES.
Topics: Bacteroides; Biotin; Choline; Coenzyme A; Culture Media; Entamoeba histolytica; Folic Acid; Pantetheine; Pyridoxine; Research; Spectrophotometry; Thiamine | 1963 |
[CLINICAL EFFECTS OF PANTETHINE ON NEUROLOGICAL DISORDERS].
Topics: Drug Therapy; Humans; Nervous System Diseases; Pantetheine; Pantothenic Acid; Pharmacology | 1965 |
Pantethine and casein hydrolyzate in the growth of certain lactobacilli.
Topics: Caseins; Humans; Lactobacillus; Pantetheine | 1955 |
Phosphorylation of pantothenic acid and pantethine by an enzyme from Proteus morganii.
Topics: Pantetheine; Pantothenic Acid; Phosphorylation; Proteus | 1955 |
The comparative activities of pantethine, pantothenic acid, and coenzyme A for various microorganisms.
Topics: Coenzyme A; Humans; Pantetheine; Pantothenic Acid | 1951 |
I. Activity of LBF (pantethine) in acetylation of sulfanilamide by pigeon liver extract.
Topics: Acetylation; Animals; Columbidae; Liver; Liver Extracts; Pantetheine; Pantothenic Acid; Sulfanilamide; Sulfanilamides | 1951 |
PANTETHINE, pantothenic acid and the Lactobacillus bulgaricus factor.
Topics: Humans; Lactobacillus; Pantetheine; Pantothenic Acid | 1951 |
An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.
Topics: Acyl Coenzyme A; Arabidopsis; Arabidopsis Proteins; Coenzyme A; DNA, Bacterial; Fatty Acids; Molecular Sequence Data; Mutagenesis, Insertional; Pantetheine; Phenotype; RNA, Messenger; Seedlings; Seeds; Sucrose | 2006 |
Protection against cerebral malaria by the low-molecular-weight thiol pantethine.
Topics: Animals; Blood-Brain Barrier; Cell Line; Cell Line, Transformed; Female; Humans; Malaria, Cerebral; Mice; Mice, Inbred CBA; Molecular Weight; Pantetheine; Permeability; Plasmodium berghei; Platelet Aggregation; Platelet Aggregation Inhibitors; Syndrome | 2008 |
Topical apolipoprotein A-1 may have a beneficial effect on the corneal epithelium in a mouse model of dry eye: a pilot study.
Topics: Administration, Topical; Animals; Apolipoprotein A-I; Corneal Diseases; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Dry Eye Syndromes; Epithelium, Corneal; Male; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Pantetheine; Pilot Projects; Treatment Outcome | 2008 |
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Topics: Animals; Brain; Coenzyme A; Drosophila; Gene Expression Regulation; Humans; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Oxygen; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Phenotype; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Brain Diseases, Metabolic; Dopamine; Electron Transport Complex I; Encephalitis; Energy Metabolism; Glutathione; Hydroxybutyrate Dehydrogenase; Ketone Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Pantetheine; Parkinsonian Disorders; Substantia Nigra; Up-Regulation | 2010 |
Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa.
Topics: Biosynthetic Pathways; Carboxy-Lyases; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, Essential; Genetic Complementation Test; Multienzyme Complexes; Pantetheine; Peptide Synthases; Pseudomonas aeruginosa | 2011 |
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
Topics: Acetylation; Animals; Coenzyme A; Disease Models, Animal; Drosophila; Histones; Humans; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Protein Processing, Post-Translational; Tubulin | 2011 |
The role of nutraceutical supplements in the treatment of dyslipidemia.
Topics: Atherosclerosis; Dietary Fats; Dietary Supplements; Dyslipidemias; Humans; Lipoproteins; Lipoproteins, VLDL; Oxidative Stress; Pantetheine; Resveratrol; Stilbenes; Tocotrienols; Triglycerides; Vascular Diseases; Vasodilator Agents | 2012 |
Self-assembly of protein aggregates in ageing disorders: the lens and cataract model.
Topics: Aging; alpha-Crystallin B Chain; Animals; Cataract; Lens, Crystalline; Models, Biological; Molecular Chaperones; Pantetheine; Protein Conformation; Protein Unfolding | 2013 |
Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.
Topics: Acyl Carrier Protein; Amino Acid Sequence; Chromatography, High Pressure Liquid; Coenzyme A; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Mass Spectrometry; Metabolic Networks and Pathways; Molecular Sequence Data; Pantetheine; Peptide Synthases; Phosphotransferases (Alcohol Group Acceptor); Urea | 2013 |
D-pantethine has vitamin activity equivalent to d-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats.
Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet; Male; Organ Size; Pantetheine; Pantothenic Acid; Rats; Rats, Wistar; Vitamins; Weaning | 2013 |
Integrated electroosmotic perfusion of tissue with online microfluidic analysis to track the metabolism of cystamine, pantethine, and coenzyme A.
Topics: Calibration; Coenzyme A; Cystamine; Electroosmosis; Extracellular Space; Hippocampus; Microfluidic Analytical Techniques; Pantetheine; Perfusion; Systems Integration | 2013 |
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
Topics: Animals; Behavior, Animal; Brain; Cholesterol; Diet, Ketogenic; Energy Metabolism; Female; Heredodegenerative Disorders, Nervous System; Immunohistochemistry; Male; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron; Mitochondria; Motor Skills; Neurons; Pantetheine; Peripheral Nervous System; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Sciatic Nerve; Triglycerides | 2014 |
The synthesis of minds and molecules leads to potential therapy for pantothenate kinase-associated neurodegeneration.
Topics: Animals; Diet, Ketogenic; Female; Heredodegenerative Disorders, Nervous System; Male; Pantetheine; Phosphotransferases (Alcohol Group Acceptor) | 2014 |
Development and validation of a stability-indicating LC-UV method for the determination of pantethine and its degradation product based on a forced degradation study.
Topics: Capsules; Chromatography, Liquid; Drug Stability; Limit of Detection; Molecular Structure; Pantetheine; Parabens; Tandem Mass Spectrometry; Ultraviolet Rays | 2014 |
Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cisplatin; Doxorubicin; Drug Synergism; HCT116 Cells; HL-60 Cells; Humans; Jurkat Cells; Male; Oxidation-Reduction; Oxidoreductases; Pantetheine; Rats; Rats, Wistar; Selenomethionine; Sodium Selenite; Tumor Cells, Cultured | 2014 |
[Deceleration of cataract development in rats under the action of N-acetylcarnosine and D-pantethine mixture].
Topics: Animals; Carnosine; Cataract; Chromatography, Gel; Drug Combinations; Eye Proteins; Injections, Intraperitoneal; Lens, Crystalline; Male; Ophthalmic Solutions; Pantetheine; Protective Agents; Protein Aggregates; Radiation Injuries, Experimental; Rats; Rats, Wistar; Solubility; Ultraviolet Rays | 2014 |
Targeting microparticle biogenesis: a novel approach to the circumvention of cancer multidrug resistance.
Topics: Acrylates; Amides; Antineoplastic Agents; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Cell-Derived Microparticles; Cystamine; Cysteamine; Drug Resistance, Neoplasm; Female; Humans; Molecular Targeted Therapy; Oligopeptides; Pantetheine; Pyridines; Verapamil | 2015 |
Pantethine Alters Lipid Composition and Cholesterol Content of Membrane Rafts, With Down-Regulation of CXCL12-Induced T Cell Migration.
Topics: Animals; Cell Movement; Chemokine CXCL12; Cholesterol; Down-Regulation; Humans; Jurkat Cells; Lipids; Lymphocyte Activation; Pantetheine; Rats; Signal Transduction; T-Lymphocytes | 2015 |
Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter 1; Bleomycin; Cell-Derived Microparticles; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Homeostasis; Hypochlorous Acid; In Vitro Techniques; Injections, Intradermal; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Pantetheine; Scleroderma, Systemic; Treatment Outcome | 2015 |
Antioxidants selenomethionine and D-pantethine decrease the negative side effects of doxorubicin in NL/Ly lymphoma-bearing mice.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Aspartate Aminotransferases; Doxorubicin; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Lymphoma; Male; Mice; Mice, Inbred BALB C; Pantetheine; Selenomethionine; Tumor Cells, Cultured | 2016 |
Tissue-protective activity of selenomethionine and D-panthetine in B16 melanoma-bearing mice under doxorubicin treatment is not connected with their ROS scavenging potential.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Dose-Response Relationship, Drug; Doxorubicin; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Pantetheine; Reactive Oxygen Species; Selenomethionine | 2017 |
Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Cell Survival; Cells, Cultured; Citric Acid Cycle; Disease Models, Animal; Gene Expression; Glycolysis; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-1beta; Metabolomics; Mice; Mice, Transgenic; Pantetheine; Pentose Phosphate Pathway; Presenilin-1; RNA, Messenger | 2017 |
Efficient one-pot enzymatic synthesis of dephospho coenzyme A.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Chemistry Techniques, Synthetic; Cloning, Molecular; Coenzyme A; Escherichia coli; Nucleotidyltransferases; Oxidation-Reduction; Pantetheine; Phosphotransferases (Alcohol Group Acceptor); Plasmids | 2018 |
Pantethine Down-Regulates Leukocyte Recruitment and Inflammatory Parameters in a Mouse Model of Allergic Airway Inflammation.
Topics: Allergens; Animals; Antigens, Protozoan; Bronchoalveolar Lavage; Cytokines; Disease Models, Animal; Down-Regulation; Female; Inflammation; Leukocytes; Lung; Mice; Mice, Inbred BALB C; Pantetheine; Protozoan Proteins | 2017 |
Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Biosynthetic Pathways; Cardiomyopathy, Dilated; Carnitine; Child, Preschool; Coenzyme A; Demography; Drosophila; Enzyme Stability; Female; Fibroblasts; Genes, Recessive; Heart; High-Throughput Nucleotide Sequencing; Homozygote; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Mutation; Pantetheine; Pedigree; Peptide Synthases; Reproducibility of Results; Saccharomyces cerevisiae | 2018 |
Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer's Disease Pathogenesis in a Transgenic Mouse Model.
Topics: Aggression; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Drug Administration Schedule; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Pantetheine; Phagocytosis; Time Factors | 2019 |
Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression.
Topics: Acetyltransferases; Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Farnesyl-Diphosphate Farnesyltransferase; Female; Humans; Male; Mice; Middle Aged; Neoplasm Staging; Pantetheine; Prognosis; Reactive Oxygen Species; Squalene Monooxygenase; Xenograft Model Antitumor Assays | 2022 |