Compounds > pantethine

pantethine and pantetheine

pantethine has been researched along with pantetheine in 147 studies

Research

Studies (147)

TimeframeStudies, this research(%)All Research%
pre-199082 (55.78)18.7374
1990's24 (16.33)18.2507
2000's9 (6.12)29.6817
2010's29 (19.73)24.3611
2020's3 (2.04)2.80

Authors

AuthorsStudies
Hsu, JC; Inayama, I; Ohtani, S; Tanaka, K1
Kumerova, AO; Lipsberga, ZE; Shkestere, IIa; Utno, LIa1
Noacco, C; Taboga, C; Tonutti, L1
Hamano, T; Hiramatsu, N; Kishida, T; Natake, M1
Utno, LIa1
Girgensone, MIa; Shkesters, AP; Utno, LIa1
Alling, C; Ekman, R; Vécsei, L; Widerlöv, E1
Barrientos, A; Coronel, F; De Oleo, P; Macia, M; Naranjo, P; Tornero, F; Torrente, J1
Kumerova, AO; Silova, AA; Utno, LIa1
Vécsei, L; Widerlöv, E1
Jeitner, TM; Oliver, JR1
Lau-Cam, CA; Nagiel-Ostaszewski, I1
Binaghi, P; Bruschi, F; Cellina, G; Lo Cicero, G; Penotti, M; Porcaro, E1
Haldar, J; Miaskowski, C; Ong, GL1
Barbi, G; Bertieri, RS; Donati, C1
Alling, C; Heilig, M; Vécsei, L; Widerlöv, E1
Hiramatsu, N; Kishida, T; Natake, M1
Abucham, J; Bollinger-Gruber, J; Reichlin, S1
Lu, ZL1
Kobayashi, S1
Bollinger-Gruber, JA; Reichlin, S1
Chonan, N; Eto, M; Ishii, K; Watanabe, K1
Arsenio, L; Bodria, P; Bossi, S; Lateana, M; Strata, A1
Baccarini, S; Bassi, R; Sartori, MP; Sellini, M1
Arsenio, L; Bodria, P; Magnati, G; Strata, A; Trovato, R1
Balestreri, R; Bertolini, S; Cuzzolaro, S; Daga, A; Donati, C; Elicio, N; Marcenaro, A; Saturnino, M1
Cighetti, G; Del Puppo, M; Fiorica, E; Galli Kienle, M; Paroni, R1
Biffignandi, P1
Cighetti, G; Del Puppo, M; Galli Kienle, M; Paroni, R1
Hobara, N; Nagashima, H; Watanabe, A1
Hansen, RG; Wittwer, CT; Wyse, BW1
Campanari, JC; Di Rienzo, F; Forti, N; Giannini, SD; Ziliotto, EE1
Abbate, R; Gensini, GF; Matucci, M; Neri Serneri, GG; Paniccia, R; Prisco, D; Rogasi, PG1
Collado, CM; Hsu, JC; Ohtani, S; Tanaka, K1
Cappelletti, C; Cecchi, L; Innocenti, M; Leopardi, A; Tinacci, L1
Graves, CP; Hansen, RG; Jorgensen, E; Peterson, MA; Thoene, JG; Wilson, DE; Windham, CT; Wittwer, CT; Wyse, BW1
Cighetti, G; Del Puppo, M; Galli, G; Kienle, MG; Paroni, R1
Ishihara, M; Ogawa, H; Tawara, K; Tomikawa, M1
Komatsu, H; Satoh, M; Suzuki, M1
Chierchia, I; Cicerano, U; Mancini, M; Postiglione, A; Rubba, P1
Kameyama, M; Miyahara, T; Murai, A; Nishimura, N; Sako, Y; Tanaka, T2
Hayashi, H; Kamikawa, T; Kobayashi, A; Nagao, B; Nishiyama, T; Terada, H; Yamazaki, N1
Biffignandi, P; Fanini, A; Vignola, D1
Butler, JD; Gahl, WA; Thoene, JG; Wittwer, CT; Zatz, M1
Gensini, GF; Matucci, M; Neri Serneri, GG; Prisco, D; Rogasi, PG1
Thoene, JG1
Avogaro, P; Bon, GB; Cazzolato, G; Zago, S1
Canonaco, F; Sala, R1
Azuma, I; Iida, J; Nishimura, K; Ukei, S1
Calvi, E; Gentili, P; Manzardo, S; Picciòla, G; Ravenna, F; Riva, M1
Arsenio, L; Caronna, S; Lateana, M; Magnati, G; Strata, A; Zammarchi, G1
Chiti, D; Imperiale, A; Proietti, C1
Chiti, D; Ligas, B; Proietti, C1
Colombo, L; Craveri, A; Descovich, GC; Fragiacomo, C; Gaddi, A; Montanari, G; Noseda, G; Sirtori, CR1
Carrara, P; Franceschini, G; Galbussera, M; Lovati, MR; Matturri, L; Sirtori, CR1
Branca, D; Scutari, G; Siliprandi, N1
Kobayashi, M; Nagashima, H; Nakatsukasa, S; Watamaba, A; Yoshihara, T1
Kumagai, A; Matsuoka, N; Morisaki, N; Saito, Y1
Kumagai, A; Matsuoka, N; Morisaki, N; Saito, Y; Sasaki, N; Shirai, K1
Jonas, AJ; Pellett, OL; Schneider, JA; Smith, ML; Thoene, JG1
Kita, M; Noma, A; Okamiya, T1
Butler, JD; Zatz, M2
Manna, H; Suga, T; Watanabe, T1
Minami, M; Saito, H; Yasuda, H1
Abiko, Y; Kameda, KY; Nakayasu, T; Tawara, K; Tomikawa, M1
Abiko, Y; Shibano, T1
Farina, R; Lovati, MR; Raucci, G; Sirtori, CR1
Harmony, JA; Jackson, RL; Ranganathan, S1
Arimori, S; Hiramatsu, K; Nozaki, H1
Fukuhara, C; Horiuchi, I; Kajiyama, G; Kawamoto, T; Miyoshi, A; Nakagawa, M1
Koga, Y; Komori, T; Murata, T; Oniki, H; Tsugi, H1
Nakayama, S; Negishi, K; Sakamoto, K1
Kimura, Y; Koga, Y; Komoda, T; Murata, T; Nakamura, S; Oniki, H; Yamashita, Y1
Davis, PS; Sharma, DC; Sharma, PK1
Clark, JI; Hiraoka, T1
Moiseenok, AG; Rakowska, M; Slyshenkov, VS; Wojtczak, L1
Clark, JI; Hiraoka, T; LI, XY; Thurston, GM1
Clark, JI; Livesey, JC; Steele, JE1
Clark, JI; Huang, QL1
Benedek, GB; Friberg, G; Ogun, O; Pande, J1
Fisher, DH; Szulc, ME1
Clark, JI; David, LL; Hiraoka, T; Matsushima, H1
Webster, MJ1
Cole, L; Congdon, NT; Duncan, DT; Fisher, DT; Hazelwood, DT; McNaughton, C; Pham, T; Rieger, KT; Sanchez, AT; Urist, JT; Vitale, ST; West, ST1
McCarty, MF1
Hata, Y; Hirose, N; Nakajima, K; Osono, Y1
Harding, JJ1
BROWN, GM; SNELL, EE2
GROB, EC; GRUNDBACHER, V; SCHOPPER, WH1
ANNONI, G1
AMBANELLI, U; SALVI, G1
MAINOLI, S; NICROSINI, F; PICCINELLI, O1
EARL, JM; STADTMAN, ER; VAGELOS, PR1
RUGGIERI, R1
CURIONI, GB1
BALESTRERI, R; CORREALE, L; LAMEDICA, G1
DI TOMMASI, M; NOFERI, A; SPADA, U; STARACE, G2
REEVES, RE1
KOHSAKA, M1
HUHTANEN, CN1
BROWN, GM; SNELL, EE; WARD, GB1
CRAIG, JA; SNELL, EE1
GIBBONS, AJ; GOVIER, WM1
Alejandro, S; Gonzalez-Guzman, M; Graham, IA; Larson, TR; Rodriguez, PL; Rubio, S; Serrano, R1
Keenan, JM; Pins, JJ1
Abou-Hamdan, M; Coltel, N; Cornille, E; de Reggi, M; Gharib, B; Grau, GE; Penet, MF1
Ishida, Y; Nyunt, AK; Shimada, S; Yu, Y1
Horváth, Z; Vécsei, L1
Hayflick, S; Kayser, O; Muntendam, R; Rana, A; Reijngoud, DJ; Seinen, E; Sibon, OC; Siudeja, K; Srinivasan, B; van der Want, JJ1
Abou-Hamdan, M; Cornille, E; de Reggi, M; Gharib, B; Khrestchatisky, M; Nieoullon, A1
Balibar, CJ; Hollis-Symynkywicz, MF; Tao, J1
Azumano, I; Evans, M; Kamiya, T; Napolitano, J; Rumberger, JA1
Abe, T; Itoh, H; Nishimura, F; Sato, Y; Suzuki, Y; Takeyama, M1
de Jong, J; Hayflick, S; Jackowski, S; Nollen, EA; Rana, A; Sanford, L; Sibon, OC; Siudeja, K; Srinivasan, B; Xu, L1
Houston, M1
Clark, JI1
Burkart, MD; Chapman, E; Kang, M; Kelleher, NL; La Clair, JJ; Ntai, I; Rothmann, M; Villa, R1
Fukuwatari, T; Kaneko, M; Shibata, K1
Sandberg, M; Weber, SG; Wu, J1
Brunetti, D; d'Amati, G; Dusi, S; Fagiolari, G; Fugnanesi, V; Giordano, C; Lamperti, C; Marchet, S; Moggio, M; Morbin, M; Sibon, O; Tiranti, V1
Németh, AH1
Azumano, I; Citrolo, D; Evans, M; Kamiya, T; Napolitano, JJ; Rumberger, JA1
Aprile, S; Canavesi, R; Grosa, G; Varese, E1
Berger, W; Chumak, V; Gurinovich, V; Heffeter, P; Lehka, L; Moiseenok, A; Omelyanchik, S; Panchuk, R; Skorokhyd, N; Stoika, R1
Avetisov, SÉ; Muranov, KO; Ostrovskiĭ, MA; Polianskiĭ, NB; Polunin, GS; Sheremet, NL1
Bebawy, M; Luk, F; Roseblade, A; Ung, A1
Acar, N; Bretillon, L; de Reggi, M; Gharib, B; Khrestchatisky, M; Molino, Y; van Gijsel-Bonnello, M1
Batteux, F; Chéreau, C; Chimini, G; Galland, F; Guilpain, P; Kavian, N; Lemaréchal, H; Marut, W; Naquet, P; Nicco, C; Servettaz, A; Weill, B1
Horváth, Z; Tuka, B; Vécsei, L1
Chumak, VV; Gurinovich, VA; Kozak, YS; Lehka, LV; Moiseenok, AG; Omelyanchik, SN; Panchuk, RR; Skorokhyd, NR; Stoika, RS1
Kozak, YS; Lehka, LV; Moiseenok, AG; Panchuk, RR; Skorokhyd, NR; Stoika, RS1
Baranger, K; Benech, P; de Reggi, M; Gharib, B; Khrestchatisky, M; Rivera, S; van Gijsel-Bonnello, M1
Huang, F; Sapkota, K1
Abou-Hamdan, M; Bajenoff, M; de Reggi, M; Gharib, B; Julia, V1
Abudi, S; Alhaddad, B; Anikster, Y; Avivi, C; Barel, O; Barshack, I; Berutti, R; Braunisch, M; Brundel, BJJM; Dubnov-Raz, G; Eyal, E; Grigat, M; Grzeschik, NA; Haack, TB; Haas, D; Hoffmann, GF; Iuso, A; Kanon, B; Kumbar, M; Marek-Yagel, D; Mastantuono, E; Meitinger, T; Messias, AC; Okun, JG; Perles, Z; Pode-Shakked, B; Prokisch, H; Rubinshtein, M; Salem, Y; Schüller, HJ; Schwarzmayr, T; Sibon, OCM; Strom, TM; Terrile, C; Tirosh, T; Vardi, A; Volkov, A; Wiersma, M1
Baranger, K; Benech, P; Carpentier, W; De Reggi, M; Gharib, B; Khrestchatisky, M; Rivera, S; Stephan, D; van Gijsel-Bonnello, M1
Chang, X; Jiang, Y; Wang, J; Wu, Y; Yao, B; Zhang, J1
Cseh, EK; Tóth, F; Vécsei, L1
Chen, Y; He, L; Jiang, H; Lin, M; Liu, H; Tang, E; Zhao, Y1

Reviews

8 review(s) available for pantethine and pantetheine

ArticleYear
Preclinical and clinical studies with cysteamine and pantethine related to the central nervous system.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:6

    Topics: Alcoholism; Animals; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Cysteamine; Humans; Pantetheine; Parkinson Disease

1990
[Atherosclerosis and prostaglandins: new biochemical frontiers of a more rational therapy].
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:1

    Topics: Arteriosclerosis; Cholesterol; Diet; Epoprostenol; Female; Humans; Lipoproteins; Male; Pantetheine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Risk; Thromboxanes; Triglycerides

1987
Can drugs or micronutrients prevent cataract?
    Drugs & aging, 2001, Volume: 18, Issue:7

    Topics: Aldehyde Reductase; Aspirin; Cataract; Clinical Trials as Topic; Drug Design; Estrogens; Glutathione; Humans; Pantetheine

2001
Dietary and nutraceutical options for managing the hypertriglyceridemic patient.
    Progress in cardiovascular nursing, 2006,Spring, Volume: 21, Issue:2

    Topics: Dietary Carbohydrates; Energy Intake; Evidence-Based Medicine; Exercise; Fasting; Fish Oils; Humans; Hypertriglyceridemia; Metabolic Syndrome; Niacin; Obesity; Pantetheine; Practice Guidelines as Topic; Risk Factors; Risk Reduction Behavior; Severity of Illness Index; Triglycerides; Weight Loss

2006
Current medical aspects of pantethine.
    Ideggyogyaszati szemle, 2009, Jul-30, Volume: 62, Issue:7-8

    Topics: Acetylcholine; Animals; Antioxidants; Atherosclerosis; Blood Platelets; Cataract; Central Nervous System; Coenzyme A; Cystine; Cystinosis; Dietary Carbohydrates; Fatty Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Oxidation-Reduction; Pantetheine; Pantothenic Acid; Pyruvates

2009
Pantethine. Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2010, Volume: 15, Issue:3

    Topics: Animals; Antioxidants; Apolipoproteins B; Cataract; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hyperlipidemias; Lipid Peroxides; Pantetheine

2010
OLD AND NEW NEUROENDOCRINE MOLECULES: SOMATOSTATIN, CYSTEAMINE, PANTETHINE AND KYNURENINE.
    Ideggyogyaszati szemle, 2014, Mar-30, Volume: 67, Issue:3-4

    Topics: Animals; Cysteamine; History, 20th Century; Humans; Kynurenine; Neuroendocrinology; Neurosecretory Systems; Pantetheine; Rats; Signal Transduction; Somatostatin; Tryptophan

2014
Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid.
    International journal of molecular sciences, 2021, Jan-02, Volume: 22, Issue:1

    Topics: Animals; Antioxidants; Humans; Kynurenic Acid; Metabolic Networks and Pathways; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Pantetheine; Thioctic Acid

2021

Trials

12 trial(s) available for pantethine and pantetheine

ArticleYear
[A double-blind clinical trial--the effects of pantethine on serum lipids in patients with hyperlipidemia].
    Zhonghua xin xue guan bing za zhi, 1989, Volume: 17, Issue:4

    Topics: Adult; Aged; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperlipidemias; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1989
[Effects of pantethine on blood lipids].
    Arquivos brasileiros de cardiologia, 1986, Volume: 46, Issue:4

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Female; Humans; Lipids; Male; Middle Aged; Pantetheine; Risk; Sulfhydryl Compounds; Triglycerides

1986
Effect of oral treatment with pantethine on platelet and plasma phospholipids in IIa hyperlipoproteinemia.
    Angiology, 1987, Volume: 38, Issue:3

    Topics: Administration, Oral; Adult; Aged; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Phospholipids; Sphingomyelins; Sulfhydryl Compounds

1987
Pantethine versus fenofibrate in the treatment of type II hyperlipoproteinemia.
    Monographs on atherosclerosis, 1985, Volume: 13

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Male; Pantetheine; Propionates; Random Allocation; Sulfhydryl Compounds

1985
[Clinical study of the lipotropic activity of the preparation Fosfolip].
    Minerva medica, 1983, Apr-07, Volume: 74, Issue:14-15

    Topics: Adult; Aged; Arteriosclerosis; Choline; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hyperlipidemias; Lipids; Liver Diseases; Male; Middle Aged; Pantetheine; Phosphorylcholine; Sulfhydryl Compounds

1983
Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia.
    Atherosclerosis, 1984, Volume: 50, Issue:1

    Topics: Adult; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Female; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Lipoproteins, HDL; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1984
Physiological and performance responses to supplementation with thiamin and pantothenic acid derivatives.
    European journal of applied physiology and occupational physiology, 1998, Volume: 77, Issue:6

    Topics: Adult; Bicycling; Blood Glucose; Double-Blind Method; Exercise; Exercise Test; Fatty Acids, Nonesterified; Heart Rate; Humans; Lactic Acid; Male; Oxygen Consumption; Pantetheine; Pantothenic Acid; Pulmonary Gas Exchange; Thiamine

1998
The effects of pantethine on fatty liver and fat distribution.
    Journal of atherosclerosis and thrombosis, 2000, Volume: 7, Issue:1

    Topics: Abdomen; Aged; Case-Control Studies; Fatty Liver; Female; Humans; Liver; Male; Middle Aged; Pantetheine; Tomography, X-Ray Computed

2000
Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled invest
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:8

    Topics: Adult; Apolipoproteins B; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Diet; Dietary Supplements; Double-Blind Method; Female; Health Promotion; Humans; Life Style; Male; Middle Aged; North America; Pantetheine; Risk; Vitamin B Complex

2011
Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:10

    Topics: Adult; Calcitonin Gene-Related Peptide; Drug Administration Schedule; Drug Evaluation, Preclinical; Fursultiamin; Gastrointestinal Tract; Humans; Male; Molecular Targeted Therapy; Motilin; Pantetheine; Substance P; Vasoactive Intestinal Peptide; Vitamin B Complex

2011
Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation.
    Vascular health and risk management, 2014, Volume: 10

    Topics: Adult; Anticholesteremic Agents; Biomarkers; Cholesterol; Cholesterol, LDL; Combined Modality Therapy; Coronary Disease; Female; Florida; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Ontario; Pantetheine; Patient Selection; Practice Guidelines as Topic; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2014
Pilot trial on the efficacy and safety of pantethine in children with pantothenate kinase-associated neurodegeneration: a single-arm, open-label study.
    Orphanet journal of rare diseases, 2020, 09-14, Volume: 15, Issue:1

    Topics: Child; Female; Humans; Male; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Pilot Projects; Quality of Life; Treatment Outcome

2020

Other Studies

127 other study(ies) available for pantethine and pantetheine

ArticleYear
Effects of pantethine on lipogenesis and CO2 production in the isolated hepatocytes of the chick (Gallus domesticus).
    Comparative biochemistry and physiology. Comparative physiology, 1992, Volume: 102, Issue:3

    Topics: Animals; Body Weight; Carbon Dioxide; Cell Survival; Cells, Cultured; Chickens; Fatty Acids; Lipids; Liver; Male; Organ Size; Oxidation-Reduction; Pantetheine

1992
[Study of pantothenic acid derivatives as cardiac protectors in a model of experimental ischemia and reperfusion of the isolated heart].
    Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 113, Issue:4

    Topics: Adenosine Triphosphate; Animals; Heart; In Vitro Techniques; Lactates; Lipid Peroxidation; Male; Myocardium; Pantetheine; Pantothenic Acid; Phosphocreatine; Rats; Rats, Wistar; Reperfusion Injury

1992
[Comparison of the efficacy of pantethine, acipimox, and bezafibrate on plasma lipids and index of cardiovascular risk in diabetics with dyslipidemia].
    Minerva medica, 1991, Volume: 82, Issue:10

    Topics: Bezafibrate; Cardiovascular Diseases; Diabetes Complications; Humans; Hyperlipidemias; Hypolipidemic Agents; Pantetheine; Pyrazines; Risk Factors

1991
Effects of dietary pantethine levels on contents of fatty acids and thiobarbituric acid reactive substances in the liver of rats orally administered varying amounts of autoxidized linoleate.
    Journal of nutritional science and vitaminology, 1991, Volume: 37, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Chromatography, Gas; Fatty Acids; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Liver; Male; Malondialdehyde; Pantetheine; Rats; Rats, Inbred Strains; Thiobarbiturates

1991
[Effects of pantethine on metabolism in myocardial mitochondria under the conditions of deep hypothermia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:6

    Topics: Animals; Coenzyme A; Cytosol; Hypothermia; Malate Dehydrogenase; Male; Mitochondria, Heart; Oxidoreductases; Pantetheine; Rats; Rats, Inbred Strains

1991
[Regulation of superoxide dismutase activity during deep hypothermia by simultaneous administration of water and lipid soluble antioxidants].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:6

    Topics: Animals; Catecholamines; Hypothermia; Male; Myocardium; Pantetheine; Rats; Rats, Inbred Strains; Vitamin E

1991
Dose- and time-response effects of pantethine on open-field behavior, and on central neurotransmission in rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Exploratory Behavior; Hypothalamus; Male; Neurotransmitter Agents; Norepinephrine; Pantetheine; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Sulfhydryl Compounds; Time Factors

1990
Treatment of hyperlipemia in diabetic patients on dialysis with a physiological substance.
    American journal of nephrology, 1991, Volume: 11, Issue:1

    Topics: Cholesterol; Cholesterol, VLDL; Diabetic Nephropathies; Evaluation Studies as Topic; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Failure, Chronic; Male; Middle Aged; Pantetheine; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Triglycerides

1991
[Effect of pantethine on post-heparin lipolytic activity and lipid peroxidation in the myocardium].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:1

    Topics: Animals; Antioxidants; Enzyme Activation; Heparin; Hypolipidemic Agents; Lipid Metabolism; Lipid Peroxidation; Lipids; Lipoprotein Lipase; Male; Myocardium; Pantetheine; Rats; Rats, Inbred Strains

1991
The depletion of plasma prolactin by pantethine in oestrogen-primed hyperprolactinaemic rats.
    The Journal of endocrinology, 1990, Volume: 124, Issue:3

    Topics: Administration, Oral; Animals; Cysteamine; Estradiol; Hyperprolactinemia; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Male; Pantetheine; Pituitary Gland; Prolactin; Rats; Sulfhydryl Compounds

1990
Protection by pantethine, pantothenic acid and cystamine against carbon tetrachloride-induced hepatotoxicity in the rat.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 67, Issue:2

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholesterol; Cystamine; Lipid Metabolism; Liver; Male; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Triglycerides

1990
[Evaluation of the cholesterol-lowering effectiveness of pantethine in women in perimenopausal age].
    Minerva medica, 1990, Volume: 81, Issue:6

    Topics: Cholesterol, HDL; Cholesterol, LDL; Drug Evaluation; Female; Humans; Hypercholesterolemia; Menopause; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1990
Changes in oxytocin and vasopressin content in posterior pituitary and hypothalamus following pantethine treatment.
    Life sciences, 1990, Volume: 47, Issue:6

    Topics: Analysis of Variance; Animals; Hypothalamus; Male; Oxytocin; Pantetheine; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasopressins

1990
[Pantethine, diabetes mellitus and atherosclerosis. Clinical study of 1045 patients].
    La Clinica terapeutica, 1989, Mar-31, Volume: 128, Issue:6

    Topics: Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hyperlipoproteinemias; Male; Middle Aged; Pantetheine; Product Surveillance, Postmarketing; Sulfhydryl Compounds

1989
Effects of cysteamine and pantethine on open-field behavior, hypothalamic catecholamine concentrations, and somatostatin-induced barrel rotation in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:3

    Topics: Animals; Cysteamine; Dose-Response Relationship, Drug; Drug Interactions; Hypothalamus; Male; Motor Activity; Pantetheine; Rats; Rats, Inbred Strains; Somatostatin; Stereotyped Behavior; Sulfhydryl Compounds

1989
Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate.
    Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:4

    Topics: Animals; Cytochrome P-450 Enzyme System; Cytochromes b5; Diet; Dose-Response Relationship, Drug; Electron Transport; Growth; Linoleic Acid; Linoleic Acids; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1989
Pantethine, a somatostatin depleting agent, increases food intake in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:3

    Topics: Animals; Blood Glucose; Circadian Rhythm; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Food Deprivation; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1989
Investigation of the roles of the substances in serum lipids and their constitutive fatty acids in chronic urticaria.
    The Journal of dermatology, 1989, Volume: 16, Issue:3

    Topics: Adult; Ascorbic Acid; Chronic Disease; Fatty Acids; Female; Glutathione; Humans; Lipids; Male; Middle Aged; Pantetheine; Urticaria

1989
Pantethine, a cysteamine precursor, depletes immunoreactive somatostatin and prolactin in the rat.
    Endocrinology, 1985, Volume: 117, Issue:2

    Topics: Animals; Cerebral Cortex; Duodenum; Gastric Mucosa; Hypothalamus; Intestinal Mucosa; Kinetics; Male; Pancreas; Pantetheine; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Sulfhydryl Compounds; Tissue Distribution

1985
Lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus.
    Artery, 1987, Volume: 15, Issue:1

    Topics: Adult; Aged; beta-Thromboglobulin; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds

1987
[Clinical use of pantethine by parenteral route in the treatment of hyperlipidemia].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1987, Volume: 58, Issue:5-6

    Topics: Cholesterol; Female; Humans; Hyperlipidemias; Infusions, Parenteral; Lipoproteins; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds

1987
[Various hormonal parameters (ACTH, cortisol, somatotropic hormone and prolactin) following administration of a single high dose of pantethine in healthy subjects].
    Bollettino della Societa italiana di biologia sperimentale, 1987, Feb-28, Volume: 63, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Female; Growth Hormone; Humans; Hydrocortisone; Male; Pantetheine; Pituitary Gland, Anterior; Prolactin; Sulfhydryl Compounds

1987
Effectiveness of long-term treatment with pantethine in patients with dyslipidemia.
    Clinical therapeutics, 1986, Volume: 8, Issue:5

    Topics: Cholesterol; Female; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Long-Term Care; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1986
Lipoprotein changes induced by pantethine in hyperlipoproteinemic patients: adults and children.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Aged; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Child; Cholesterol; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1986
Pantethine inhibits cholesterol and fatty acid syntheses and stimulates carbon dioxide formation in isolated rat hepatocytes.
    Journal of lipid research, 1987, Volume: 28, Issue:2

    Topics: Animals; Carbon Dioxide; Cholesterol; Fatty Acids; In Vitro Techniques; Lipid Metabolism; Liver; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1987
Modulation of HMG-CoA reductase activity by pantetheine/pantethine.
    Biochimica et biophysica acta, 1988, Nov-25, Volume: 963, Issue:2

    Topics: Animals; Enzyme Activation; Glutathione; Hydroxymethylglutaryl CoA Reductases; Kinetics; Male; Microsomes, Liver; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1988
Activation and inhibition of yeast aldehyde dehydrogenase activity by pantethine and its metabolites.
    Annals of nutrition & metabolism, 1986, Volume: 30, Issue:1

    Topics: Acetyl Coenzyme A; Aldehyde Dehydrogenase; Coenzyme A; Cysteamine; Enzyme Activation; Pantetheine; Pantothenic Acid; Saccharomyces cerevisiae; Sulfhydryl Compounds; Taurine

1986
Enzymatic hydrolysis of pantetheine.
    Methods in enzymology, 1986, Volume: 122

    Topics: Amidohydrolases; Animals; Carbon Radioisotopes; Chromatography, Paper; Electrophoresis, Polyacrylamide Gel; GPI-Linked Proteins; Indicators and Reagents; Kidney; Kinetics; Male; Pantetheine; Radioisotope Dilution Technique; Rats; Sulfhydryl Compounds; Swine; Tissue Distribution

1986
Effects of pantethine supplementation to diets with different energy cereals on hepatic lipogenesis of laying hens.
    Poultry science, 1987, Volume: 66, Issue:2

    Topics: Animal Nutritional Physiological Phenomena; Animals; Chickens; Edible Grain; Female; Lipid Metabolism; Liver; Oviposition; Pantetheine; Sulfhydryl Compounds

1987
[Thrombocytopenic purpura during treatment with pantethine].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:5

    Topics: Aged; Female; Humans; Pantetheine; Purpura, Thrombocytopenic; Sulfhydryl Compounds

1987
Pantethine lipomodulation: evidence for cysteamine mediation in vitro and in vivo.
    Atherosclerosis, 1987, Volume: 68, Issue:1-2

    Topics: Animals; Cells, Cultured; Coenzyme A; Cysteamine; Diabetes Mellitus, Experimental; Humans; Hydrolysis; Hypercholesterolemia; Lipid Metabolism; Male; Pantetheine; Rabbits; Rats; Sulfhydryl Compounds

1987
Effects of pantethine on cholesterol synthesis from mevalonate in isolated rat hepatocytes.
    Atherosclerosis, 1986, Volume: 60, Issue:1

    Topics: Animals; Carbon Radioisotopes; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Male; Mevalonic Acid; Pantetheine; Rats; Rats, Inbred Strains; Squalene; Sterol O-Acyltransferase; Sulfhydryl Compounds

1986
Effect of probucol, pantethine and their combinations on serum lipoprotein metabolism and on the incidence of atheromatous lesions in the rabbit.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:2

    Topics: Animals; Apolipoproteins; Arteriosclerosis; Cholesterol, HDL; Drug Synergism; Lipoproteins; Male; Pantetheine; Phenols; Probucol; Rabbits; Sulfhydryl Compounds

1986
[Studies on percutaneous absorption of pantethine in guinea pigs].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1986, Volume: 96, Issue:7

    Topics: Animals; Autoradiography; Guinea Pigs; Male; Pantetheine; Skin Absorption; Sulfhydryl Compounds

1986
The effects of pantethine on lipid and lipoprotein abnormalities in survivors of cerebral infarction.
    Artery, 1985, Volume: 12, Issue:4

    Topics: Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Cerebral Infarction; Cholesterol; Humans; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Pantetheine; Phospholipids; Sulfhydryl Compounds; Triglycerides

1985
Effects of pantethine on action potential of canine papillary muscle during hypoxic perfusion.
    Japanese heart journal, 1985, Volume: 26, Issue:2

    Topics: Action Potentials; Animals; Dogs; Electrophysiology; In Vitro Techniques; Membrane Potentials; Microelectrodes; Oxygen; Pantetheine; Papillary Muscles; Perfusion; Refractory Period, Electrophysiological; Sulfhydryl Compounds

1985
[Effects of D(+)-bis-(N-pantothenyl-amidoethyl)-disulphur on the blood lipid profile and apoproteins A and B levels].
    La Clinica terapeutica, 1985, Jun-30, Volume: 113, Issue:6

    Topics: Adult; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Female; Humans; Lipids; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds; Triglycerides

1985
Metabolism of pantethine in cystinosis.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:4

    Topics: Adolescent; Amidohydrolases; Animals; Child; Cysteamine; Cystine; Cystinosis; Diarrhea; Female; GPI-Linked Proteins; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Leukocytes; Male; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1985
Changes in fatty acid composition of the single platelet phospholipids induced by pantethine treatment.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:5

    Topics: Administration, Oral; Adult; Aged; Blood Platelets; Cholesterol; Cholesterol, HDL; Chromatography, Gas; Fatty Acids; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sulfhydryl Compounds; Triglycerides

1985
Therapy of cystinosis.
    Progress in clinical and biological research, 1985, Volume: 197

    Topics: Cysteamine; Cystinosis; Humans; Orphan Drug Production; Pantetheine

1985
Effects of pantethine on in-vitro peroxidation of low density lipoproteins.
    Atherosclerosis, 1985, Volume: 57, Issue:1

    Topics: Antioxidants; Apolipoproteins B; Dialysis; Glutathione; Humans; In Vitro Techniques; Lipid Peroxides; Lipoproteins, LDL; Male; Malondialdehyde; Molecular Weight; Pantetheine; Sulfhydryl Compounds

1985
[Therapeutic use of a combination containing calcium, vitamins, pantethine and carnitine in convalescence states in childhood].
    La Clinica terapeutica, 1985, Oct-31, Volume: 115, Issue:2

    Topics: Calcium; Carnitine; Child; Child, Preschool; Convalescence; Drug Combinations; Female; Humans; Infant; Male; Pantetheine; Sulfhydryl Compounds; Vitamins

1985
Macrophage activation with pantethine and pantetheine-4'-phosphate.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1985, Volume: 55, Issue:4

    Topics: Animals; Cells, Cultured; Cytotoxicity, Immunologic; Female; Kinetics; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Pantetheine; Structure-Activity Relationship; Sulfhydryl Compounds

1985
Pantetheine and pantethine esters with hypolipidemic nicotinic acid derivatives.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:12

    Topics: Animals; Chemical Phenomena; Chemistry; Fatty Acids, Nonesterified; Hypolipidemic Agents; Male; Nicotinic Acids; Pantetheine; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Triglycerides

1985
[Hyperlipidemia, diabetes and atherosclerosis: efficacy of treatment with pantethine].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1984, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aged; Apolipoproteins; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Complications; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemias; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Pantetheine; Sulfhydryl Compounds

1984
[Treatment of chronic hepatopathies with phosphorylcholine and pantethine].
    La Clinica terapeutica, 1984, Aug-15, Volume: 110, Issue:3

    Topics: Adult; Aged; Choline; Chronic Disease; Drug Combinations; Female; Humans; Liver Diseases; Male; Middle Aged; Pantetheine; Phosphorylcholine; Sulfhydryl Compounds

1984
Pantethine reduces plasma cholesterol and the severity of arterial lesions in experimental hypercholesterolemic rabbits.
    Atherosclerosis, 1984, Volume: 53, Issue:3

    Topics: Animals; Aorta, Abdominal; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins A; Cholesterol, Dietary; Cholesterol, HDL; Coronary Vessels; Hypercholesterolemia; Isoelectric Focusing; Lipoproteins, HDL; Male; Pantetheine; Rabbits; Sulfhydryl Compounds

1984
Pantethine and pantothenate effect on the CoA content of rat liver.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:2-3

    Topics: Animals; Coenzyme A; Cysteine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1984
[Effect of oral pantethine administration on blood acetaldehyde levels following alcohol ingestion].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1984, Volume: 81, Issue:12

    Topics: Acetaldehyde; Administration, Oral; Adult; Alcohol Drinking; Humans; Male; Pantetheine; Sulfhydryl Compounds

1984
Effects of pantethine and its metabolites on fatty acid oxidation in rat liver mitochondria.
    The Tohoku journal of experimental medicine, 1983, Volume: 141, Issue:1

    Topics: Acyl Coenzyme A; Animals; Carnitine Acyltransferases; Coenzyme A Ligases; Fatty Acids; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Pantetheine; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sulfhydryl Compounds

1983
Effect of pantethine on fatty acid oxidation in microvessels of rat brain.
    The Tohoku journal of experimental medicine, 1983, Volume: 141, Issue:1

    Topics: Animals; Brain; Cerebral Hemorrhage; Fatty Acids; Hypertension; In Vitro Techniques; Microcirculation; Pantetheine; Rats; Sulfhydryl Compounds

1983
Renal cell culture using autopsy material from children with cystinosis.
    In vitro, 1984, Volume: 20, Issue:1

    Topics: Autopsy; Cells, Cultured; Child, Preschool; Cysteamine; Cystine; Cystinosis; Fibroblasts; Humans; Kidney; Male; Pantetheine

1984
Effect of pantethine on post-heparin plasma lipolytic activities and adipose tissue lipoprotein lipase in rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:5

    Topics: Adipose Tissue; Animals; Body Weight; Chromatography, Agarose; Epididymis; Hyperlipidemias; Lipids; Lipoprotein Lipase; Liver; Male; Organ Size; Pantetheine; Rats; Rats, Inbred Strains; Sepharose; Subcellular Fractions; Sulfhydryl Compounds

1984
Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine-cysteine mixed disulfide.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:2

    Topics: Cells, Cultured; Child; Cystamine; Cystine; Cystinosis; Fibroblasts; Humans; Kinetics; Pantetheine; Skin; Sulfhydryl Compounds

1984
Effects of some hypolipidemic drugs on biochemical values and on hepatic peroxisomal enzymes of normolipemic rat.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:10

    Topics: Animals; Carnitine O-Acetyltransferase; Cyclohexanols; Hypolipidemic Agents; Liver; Lovastatin; Microbodies; Naphthalenes; Nicotinic Acids; Organoids; Pantetheine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Riboflavin

1981
Pantethine depletes cystinotic fibroblasts of cystine.
    The Journal of pediatrics, 1983, Volume: 102, Issue:5

    Topics: Cells, Cultured; Cystamine; Cystine; Cystinosis; Dose-Response Relationship, Drug; Fibroblasts; Humans; Pantetheine; Sulfhydryl Compounds

1983
Positive inotropic and negative chronotropic effect of pantethine on isolated cardiac muscle of guinea-pigs.
    Experientia, 1983, Sep-15, Volume: 39, Issue:9

    Topics: Animals; Depression, Chemical; Guinea Pigs; Heart Atria; Heart Rate; Myocardial Contraction; Pantetheine; Stimulation, Chemical; Sulfhydryl Compounds

1983
Effect of pantethine on lipoprotein profiles and HDL subfractions in experimentally hypercholesterolemic rabbits.
    Atherosclerosis, 1982, Volume: 41, Issue:2-3

    Topics: Animals; Cholesterol, Dietary; Hypercholesterolemia; Lipoproteins; Lipoproteins, HDL; Male; Pantetheine; Rabbits; Sulfhydryl Compounds

1982
Effect of pantethine on myocardial pH reduced by partial occlusion of the coronary artery in dogs with special reference to the myocardial levels of adenosine triphosphate, creatine phosphate, and lactate.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 255, Issue:2

    Topics: Adenosine Triphosphate; Animals; Coronary Disease; Dogs; Female; Hemodynamics; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Pantetheine; Phosphocreatine; Sulfhydryl Compounds; Time Factors

1982
Effects of pantethine on different models of experimental hyperlipidemia in rodents: a comparison with clofibrate.
    Pharmacological research communications, 1982, Volume: 14, Issue:6

    Topics: Animals; Clofibrate; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, HDL; Male; Pantetheine; Rats; Sulfhydryl Compounds

1982
Effect of pantethine on the biosynthesis of cholesterol in human skin fibroblasts.
    Atherosclerosis, 1982, Volume: 44, Issue:3

    Topics: Acetates; Cholesterol; Depression, Chemical; DNA; Fatty Acids; Fibroblasts; Humans; Lanosterol; Mevalonic Acid; Pantetheine; Protein Biosynthesis; Skin; Sulfhydryl Compounds

1982
[Effect of pantethine on the lipoprotein abnormalities in survivors of cerebral infarction (author's transl)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1980, Volume: 17, Issue:6

    Topics: Cerebral Infarction; Cholesterol; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Pantetheine; Sulfhydryl Compounds

1980
Influence of pantethine on platelet volume, microviscosity, lipid composition and functions in diabetes mellitus with hyperlipidemia.
    The Tokai journal of experimental and clinical medicine, 1981, Volume: 6, Issue:1

    Topics: Blood Platelets; Blood Viscosity; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyperglycemia; Lipids; Male; Pantetheine; Platelet Adhesiveness; Platelet Aggregation; Sulfhydryl Compounds

1981
The effect of pantethine, a precursor of coenzyme A, on bile acids and lipids in rats fed with a cholesterol diet.
    Hiroshima journal of medical sciences, 1981, Volume: 30, Issue:3

    Topics: Animals; Bile Acids and Salts; Cholesterol, Dietary; Female; Lipid Metabolism; Lipids; Pantetheine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1981
[Study of enhancement of LCAT activity (author's transl)].
    Igaku kenkyu. Acta medica, 1980, Volume: 50, Issue:3

    Topics: Adult; Arteriosclerosis; Drug Therapy, Combination; Humans; Kidney Diseases; Male; Pantetheine; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines

1980
[Effects of soysterol, pantethine and dl-alpha-tocopheryl nicotinate on hyperlipemia in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:3

    Topics: Animals; Body Weight; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Nicotinic Acids; Organ Size; Pantetheine; Phytosterols; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vitamin E

1981
[Relationship between ADCC effector cells and the combination therapy of pantethine and lecithin--a proposal for management of patients with HBsAg carrier state (author's transl)].
    Igaku kenkyu. Acta medica, 1981, Volume: 51, Issue:4

    Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Carrier State; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Male; Middle Aged; Pantetheine; Phosphatidylcholines; Sulfhydryl Compounds

1981
Studies in search of modifiers of the toxicity of mercurials and speculations on its biochemical mechanism.
    Biochemical pharmacology, 1981, Nov-15, Volume: 30, Issue:22

    Topics: Animals; Coenzyme A; Cysteine; Glutathione; Goldfish; Mercury; Methylmercury Compounds; Pantetheine

1981
Inhibition of lens opacification during the early stages of cataract formation.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:12

    Topics: Animals; Animals, Newborn; Cataract; Disease Models, Animal; Female; Injections, Subcutaneous; Lens, Crystalline; Male; Pantetheine; Rats; Rats, Sprague-Dawley; Sodium Selenite; Time Factors

1995
Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation.
    Free radical biology & medicine, 1995, Volume: 19, Issue:6

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Coenzyme A; Fatty Acids; Female; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Mice; Palmitic Acid; Palmitic Acids; Pantetheine; Pantothenic Acid; Thiobarbituric Acid Reactive Substances

1995
Effect of selected anti-cataract agents on opacification in the selenite cataract model.
    Experimental eye research, 1996, Volume: 62, Issue:1

    Topics: Animals; Antioxidants; Cataract; Chelating Agents; Disulfides; Pantetheine; Phosphates; Rats; Rats, Sprague-Dawley; Sodium Selenite; Temperature; Tissue Extracts

1996
Delay or inhibition of rat lens opacification using pantethine and WR-77913.
    Experimental eye research, 1996, Volume: 62, Issue:1

    Topics: Amifostine; Animals; Cataract; Female; Galactose; Lens, Crystalline; Male; Pantetheine; Protein Denaturation; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Sodium Selenite; Streptozocin

1996
Modulation of the chaperone-like activity of bovine alpha-crystallin.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Dec-24, Volume: 93, Issue:26

    Topics: Alcohol Dehydrogenase; Animals; Cattle; Crystallins; Glutathione; Kinetics; Molecular Chaperones; Pantetheine; Protein Denaturation; Time Factors

1996
Pantethine inhibits the formation of high-Tc protein aggregates in gamma B crystallin solutions.
    Current eye research, 1996, Volume: 15, Issue:12

    Topics: Animals; Animals, Newborn; Biopolymers; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Hydrogen-Ion Concentration; Lens, Crystalline; Pantetheine

1996
Reduction of pantethine in rabbit ocular lens homogenate.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 15, Issue:5

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Lens, Crystalline; Oxidation-Reduction; Pantetheine; Rabbits

1997
Loss of cytoskeletal proteins and lens cell opacification in the selenite cataract model.
    Experimental eye research, 1997, Volume: 64, Issue:3

    Topics: Actins; Animals; Blotting, Western; Cataract; Crystallins; Cytoskeletal Proteins; Disease Progression; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Pantetheine; Rats; Rats, Sprague-Dawley; Sodium Selenite; Spectrin; Tubulin; Vimentin

1997
Pantethine.
    Alternative medicine review : a journal of clinical therapeutic, 1998, Volume: 3, Issue:5

    Topics: Humans; Pantetheine

1998
The effect of pantethine and ultraviolet-B radiation on the development of lenticular opacity in the emory mouse.
    Current eye research, 2000, Volume: 20, Issue:1

    Topics: Animals; Cataract; Cysteamine; Disease Models, Animal; Disease Progression; Female; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Pantetheine; Ultraviolet Rays

2000
Inhibition of acetyl-CoA carboxylase by cystamine may mediate the hypotriglyceridemic activity of pantethine.
    Medical hypotheses, 2001, Volume: 56, Issue:3

    Topics: Acetyl-CoA Carboxylase; Animals; Cholesterol; Cystamine; Fatty Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Liver; Models, Biological; Obesity; Pantetheine; Triglycerides

2001
The relationship of pantethine to naturally occurring forms of the Lactobacillus bulgaricus factor.
    The Journal of biological chemistry, 1952, Volume: 198, Issue:1

    Topics: Lactobacillus; Pantetheine; Pantothenic Acid; Sulfhydryl Compounds

1952
Pantethine and related forms of the Lactobacillus bulgaricus factor (LBF).
    Advances in enzymology and related subjects of biochemistry, 1953, Volume: 14

    Topics: Lactobacillus; Pantetheine; Pantothenic Acid

1953
[Effect of pantothenic acid, pantethine and phosphorylated pantethine on carotene formation in Mucor hiemalis].
    Experientia, 1954, Sep-15, Volume: 10, Issue:9

    Topics: Carotenoids; Fungi; Lipogenesis; Mucor; Pantetheine; Pantothenic Acid; Pigments, Biological

1954
[Pantethine].
    Il Farmaco; edizione pratica, 1955, Volume: 10, Issue:6

    Topics: Pantetheine; Pantothenic Acid

1955
[Initial clinical experiments with pantethine].
    Il Farmaco; edizione scientifica, 1955, Volume: 10, Issue:10

    Topics: Humans; Pantetheine; Pantothenic Acid

1955
[Effect of pantethine on Co60 distribution].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:12

    Topics: Cobalt; Pantetheine; Pantothenic Acid; Sulfides

1956
[Lipotropic & liver protective effect of pantethine in experimental liver diseases induced by Handler diet & carbon tetrachloride].
    Il Farmaco; edizione scientifica, 1957, Volume: 12, Issue:10

    Topics: Carbon Tetrachloride; Diet; Lipotropic Agents; Liver Diseases; Pantetheine; Pantothenic Acid; Sulfides

1957
Propionic acid metabolism. II. Enzymatic synthesis of lactyl pantethine.
    The Journal of biological chemistry, 1959, Volume: 234, Issue:4

    Topics: Lactates; Pantetheine; Pantothenic Acid; Propionates; Pseudomonas

1959
[Determination of pantethine in the presence of pantothenic acid].
    Bollettino chimico farmaceutico, 1961, Volume: 100

    Topics: Health Services; Pantetheine; Pantothenic Acid

1961
[The action of pantethine on the take of the homoplastic bone grafts].
    Archivio di ortopedia, 1959, Volume: 72

    Topics: Amines; Bone Transplantation; Humans; Pantetheine; Pantothenic Acid

1959
[In vitro effect of pantethine on the secretion of 21-C-corticosteroids by the ox adrenal].
    Archivio "E. Maragliano" di patologia e clinica, 1962, Volume: 18

    Topics: Adrenal Cortex Hormones; Glucocorticoids; In Vitro Techniques; Pantetheine; Pantothenic Acid; Pregnadienes

1962
[Histochemical aspects of the rat lung after treatment with prednisone and prednisone-pantethine].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Animals; Lung Diseases; Pantetheine; Pantothenic Acid; Prednisone; Rats

1963
[Inhibition by pantethine of pulmonary hemorrhagic manifestations caused by prednisone. Experimental research in the rat].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Animals; Hemorrhage; Lung Diseases; Pantetheine; Pantothenic Acid; Prednisone; Rats

1963
PANTETHINE-REQUIRING BACTEROIDES.
    Journal of bacteriology, 1963, Volume: 85

    Topics: Bacteroides; Biotin; Choline; Coenzyme A; Culture Media; Entamoeba histolytica; Folic Acid; Pantetheine; Pyridoxine; Research; Spectrophotometry; Thiamine

1963
[CLINICAL EFFECTS OF PANTETHINE ON NEUROLOGICAL DISORDERS].
    No to shinkei = Brain and nerve, 1965, Volume: 17

    Topics: Drug Therapy; Humans; Nervous System Diseases; Pantetheine; Pantothenic Acid; Pharmacology

1965
Pantethine and casein hydrolyzate in the growth of certain lactobacilli.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 88, Issue:2

    Topics: Caseins; Humans; Lactobacillus; Pantetheine

1955
Phosphorylation of pantothenic acid and pantethine by an enzyme from Proteus morganii.
    The Journal of biological chemistry, 1955, Volume: 213, Issue:2

    Topics: Pantetheine; Pantothenic Acid; Phosphorylation; Proteus

1955
The comparative activities of pantethine, pantothenic acid, and coenzyme A for various microorganisms.
    Journal of bacteriology, 1951, Volume: 61, Issue:3

    Topics: Coenzyme A; Humans; Pantetheine; Pantothenic Acid

1951
I. Activity of LBF (pantethine) in acetylation of sulfanilamide by pigeon liver extract.
    Archives of biochemistry and biophysics, 1951, Volume: 32, Issue:2

    Topics: Acetylation; Animals; Columbidae; Liver; Liver Extracts; Pantetheine; Pantothenic Acid; Sulfanilamide; Sulfanilamides

1951
PANTETHINE, pantothenic acid and the Lactobacillus bulgaricus factor.
    Nutrition reviews, 1951, Volume: 9, Issue:8

    Topics: Humans; Lactobacillus; Pantetheine; Pantothenic Acid

1951
An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.
    Plant physiology, 2006, Volume: 140, Issue:3

    Topics: Acyl Coenzyme A; Arabidopsis; Arabidopsis Proteins; Coenzyme A; DNA, Bacterial; Fatty Acids; Molecular Sequence Data; Mutagenesis, Insertional; Pantetheine; Phenotype; RNA, Messenger; Seedlings; Seeds; Sucrose

2006
Protection against cerebral malaria by the low-molecular-weight thiol pantethine.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jan-29, Volume: 105, Issue:4

    Topics: Animals; Blood-Brain Barrier; Cell Line; Cell Line, Transformed; Female; Humans; Malaria, Cerebral; Mice; Mice, Inbred CBA; Molecular Weight; Pantetheine; Permeability; Plasmodium berghei; Platelet Aggregation; Platelet Aggregation Inhibitors; Syndrome

2008
Topical apolipoprotein A-1 may have a beneficial effect on the corneal epithelium in a mouse model of dry eye: a pilot study.
    Eye & contact lens, 2008, Volume: 34, Issue:5

    Topics: Administration, Topical; Animals; Apolipoprotein A-I; Corneal Diseases; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Dry Eye Syndromes; Epithelium, Corneal; Male; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Pantetheine; Pilot Projects; Treatment Outcome

2008
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Apr-13, Volume: 107, Issue:15

    Topics: Animals; Brain; Coenzyme A; Drosophila; Gene Expression Regulation; Humans; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Oxygen; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Phenotype; Phosphotransferases (Alcohol Group Acceptor)

2010
Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.
    BMC neuroscience, 2010, Apr-23, Volume: 11

    Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Brain Diseases, Metabolic; Dopamine; Electron Transport Complex I; Encephalitis; Energy Metabolism; Glutathione; Hydroxybutyrate Dehydrogenase; Ketone Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Pantetheine; Parkinsonian Disorders; Substantia Nigra; Up-Regulation

2010
Pantethine rescues phosphopantothenoylcysteine synthetase and phosphopantothenoylcysteine decarboxylase deficiency in Escherichia coli but not in Pseudomonas aeruginosa.
    Journal of bacteriology, 2011, Volume: 193, Issue:13

    Topics: Biosynthetic Pathways; Carboxy-Lyases; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, Essential; Genetic Complementation Test; Multienzyme Complexes; Pantetheine; Peptide Synthases; Pseudomonas aeruginosa

2011
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
    EMBO molecular medicine, 2011, Volume: 3, Issue:12

    Topics: Acetylation; Animals; Coenzyme A; Disease Models, Animal; Drosophila; Histones; Humans; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Protein Processing, Post-Translational; Tubulin

2011
The role of nutraceutical supplements in the treatment of dyslipidemia.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:2

    Topics: Atherosclerosis; Dietary Fats; Dietary Supplements; Dyslipidemias; Humans; Lipoproteins; Lipoproteins, VLDL; Oxidative Stress; Pantetheine; Resveratrol; Stilbenes; Tocotrienols; Triglycerides; Vascular Diseases; Vasodilator Agents

2012
Self-assembly of protein aggregates in ageing disorders: the lens and cataract model.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013, May-05, Volume: 368, Issue:1617

    Topics: Aging; alpha-Crystallin B Chain; Animals; Cataract; Lens, Crystalline; Models, Biological; Molecular Chaperones; Pantetheine; Protein Conformation; Protein Unfolding

2013
Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.
    Journal of the American Chemical Society, 2013, Apr-24, Volume: 135, Issue:16

    Topics: Acyl Carrier Protein; Amino Acid Sequence; Chromatography, High Pressure Liquid; Coenzyme A; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Mass Spectrometry; Metabolic Networks and Pathways; Molecular Sequence Data; Pantetheine; Peptide Synthases; Phosphotransferases (Alcohol Group Acceptor); Urea

2013
D-pantethine has vitamin activity equivalent to d-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet; Male; Organ Size; Pantetheine; Pantothenic Acid; Rats; Rats, Wistar; Vitamins; Weaning

2013
Integrated electroosmotic perfusion of tissue with online microfluidic analysis to track the metabolism of cystamine, pantethine, and coenzyme A.
    Analytical chemistry, 2013, Dec-17, Volume: 85, Issue:24

    Topics: Calibration; Coenzyme A; Cystamine; Electroosmosis; Extracellular Space; Hippocampus; Microfluidic Analytical Techniques; Pantetheine; Perfusion; Systems Integration

2013
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 1

    Topics: Animals; Behavior, Animal; Brain; Cholesterol; Diet, Ketogenic; Energy Metabolism; Female; Heredodegenerative Disorders, Nervous System; Immunohistochemistry; Male; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron; Mitochondria; Motor Skills; Neurons; Pantetheine; Peripheral Nervous System; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Sciatic Nerve; Triglycerides

2014
The synthesis of minds and molecules leads to potential therapy for pantothenate kinase-associated neurodegeneration.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 1

    Topics: Animals; Diet, Ketogenic; Female; Heredodegenerative Disorders, Nervous System; Male; Pantetheine; Phosphotransferases (Alcohol Group Acceptor)

2014
Development and validation of a stability-indicating LC-UV method for the determination of pantethine and its degradation product based on a forced degradation study.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 97

    Topics: Capsules; Chromatography, Liquid; Drug Stability; Limit of Detection; Molecular Structure; Pantetheine; Parabens; Tandem Mass Spectrometry; Ultraviolet Rays

2014
Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study.
    Croatian medical journal, 2014, Jun-01, Volume: 55, Issue:3

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cisplatin; Doxorubicin; Drug Synergism; HCT116 Cells; HL-60 Cells; Humans; Jurkat Cells; Male; Oxidation-Reduction; Oxidoreductases; Pantetheine; Rats; Rats, Wistar; Selenomethionine; Sodium Selenite; Tumor Cells, Cultured

2014
[Deceleration of cataract development in rats under the action of N-acetylcarnosine and D-pantethine mixture].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:11

    Topics: Animals; Carnosine; Cataract; Chromatography, Gel; Drug Combinations; Eye Proteins; Injections, Intraperitoneal; Lens, Crystalline; Male; Ophthalmic Solutions; Pantetheine; Protective Agents; Protein Aggregates; Radiation Injuries, Experimental; Rats; Rats, Wistar; Solubility; Ultraviolet Rays

2014
Targeting microparticle biogenesis: a novel approach to the circumvention of cancer multidrug resistance.
    Current cancer drug targets, 2015, Volume: 15, Issue:3

    Topics: Acrylates; Amides; Antineoplastic Agents; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Cell-Derived Microparticles; Cystamine; Cysteamine; Drug Resistance, Neoplasm; Female; Humans; Molecular Targeted Therapy; Oligopeptides; Pantetheine; Pyridines; Verapamil

2015
Pantethine Alters Lipid Composition and Cholesterol Content of Membrane Rafts, With Down-Regulation of CXCL12-Induced T Cell Migration.
    Journal of cellular physiology, 2015, Volume: 230, Issue:10

    Topics: Animals; Cell Movement; Chemokine CXCL12; Cholesterol; Down-Regulation; Humans; Jurkat Cells; Lipids; Lymphocyte Activation; Pantetheine; Rats; Signal Transduction; T-Lymphocytes

2015
Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:7

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter 1; Bleomycin; Cell-Derived Microparticles; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Homeostasis; Hypochlorous Acid; In Vitro Techniques; Injections, Intradermal; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Pantetheine; Scleroderma, Systemic; Treatment Outcome

2015
Antioxidants selenomethionine and D-pantethine decrease the negative side effects of doxorubicin in NL/Ly lymphoma-bearing mice.
    Croatian medical journal, 2016, Apr-23, Volume: 57, Issue:2

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Aspartate Aminotransferases; Doxorubicin; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Lymphoma; Male; Mice; Mice, Inbred BALB C; Pantetheine; Selenomethionine; Tumor Cells, Cultured

2016
Tissue-protective activity of selenomethionine and D-panthetine in B16 melanoma-bearing mice under doxorubicin treatment is not connected with their ROS scavenging potential.
    Croatian medical journal, 2017, Apr-14, Volume: 58, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Dose-Response Relationship, Drug; Doxorubicin; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Pantetheine; Reactive Oxygen Species; Selenomethionine

2017
Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Cell Survival; Cells, Cultured; Citric Acid Cycle; Disease Models, Animal; Gene Expression; Glycolysis; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-1beta; Metabolomics; Mice; Mice, Transgenic; Pantetheine; Pentose Phosphate Pathway; Presenilin-1; RNA, Messenger

2017
Efficient one-pot enzymatic synthesis of dephospho coenzyme A.
    Bioorganic chemistry, 2018, Volume: 76

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Chemistry Techniques, Synthetic; Cloning, Molecular; Coenzyme A; Escherichia coli; Nucleotidyltransferases; Oxidation-Reduction; Pantetheine; Phosphotransferases (Alcohol Group Acceptor); Plasmids

2018
Pantethine Down-Regulates Leukocyte Recruitment and Inflammatory Parameters in a Mouse Model of Allergic Airway Inflammation.
    Medical science monitor basic research, 2017, Nov-27, Volume: 23

    Topics: Allergens; Animals; Antigens, Protozoan; Bronchoalveolar Lavage; Cytokines; Disease Models, Animal; Down-Regulation; Female; Inflammation; Leukocytes; Lung; Mice; Mice, Inbred BALB C; Pantetheine; Protozoan Proteins

2017
Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy.
    American journal of human genetics, 2018, 06-07, Volume: 102, Issue:6

    Topics: Amino Acid Sequence; Animals; Biosynthetic Pathways; Cardiomyopathy, Dilated; Carnitine; Child, Preschool; Coenzyme A; Demography; Drosophila; Enzyme Stability; Female; Fibroblasts; Genes, Recessive; Heart; High-Throughput Nucleotide Sequencing; Homozygote; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Mutation; Pantetheine; Pedigree; Peptide Synthases; Reproducibility of Results; Saccharomyces cerevisiae

2018
Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer's Disease Pathogenesis in a Transgenic Mouse Model.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2019, Volume: 16, Issue:4

    Topics: Aggression; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Drug Administration Schedule; Hippocampus; Humans; Male; Mice; Mice, Transgenic; Pantetheine; Phagocytosis; Time Factors

2019
Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression.
    Cancer science, 2022, Volume: 113, Issue:3

    Topics: Acetyltransferases; Aged; Aged, 80 and over; Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Farnesyl-Diphosphate Farnesyltransferase; Female; Humans; Male; Mice; Middle Aged; Neoplasm Staging; Pantetheine; Prognosis; Reactive Oxygen Species; Squalene Monooxygenase; Xenograft Model Antitumor Assays

2022