Page last updated: 2024-08-25

panipenem and meropenem

panipenem has been researched along with meropenem in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (40.00)	18.2507
2000's	22 (55.00)	29.6817
2010's	2 (5.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jolivette, LJ; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Goto, T; Ichiishi, T; Mikamo, H; Nakao, K; Tanaka, K; Watanabe, K; Yamagishi, Y	1
Iwata, S; Murayama, SY; Nakayama, E; Sakata, H; Seki, C; Sunakawa, K; Sunaoshi, K; Ubukata, K	1
Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A	1
Matano, H; Morooka, T; Shibata, M; Yamaguchi, S	1
Matsumura, H; Nouda, H; Sumita, Y; Sunagawa, M	1
Endoh, K; Goto, H; Igarashi, H; Kawahara, M; Kiyota, H; Machida, T; Mitani, H; Onodera, S; Suzuki, H; Takamizawa, S	1
Hashizume, T; Hazumi, N; Kato, Y; Matsuda, K	1
Deguchi, K; Fukayama, S; Fukumoto, T; Ishihara, R; Koguchi, M; Nakane, Y; Oda, S; Suzuki, Y; Tanaka, S	1
Kanazawa, K; Nouda, H; Sunagawa, M	1
Hirata, Y; Igari, J; Imafuku, Y; Inoue, M; Ishigo, S; Kawaguchi, R; Kobayashi, I; Kumasaka, K; Matsuoka, K; Murakami, E; Nishino, T; Oguri, T; Ohtaki, Y; Okada, J; Okamoto, E; Saeki, H; Satou, S; Shibano, T; Takahashi, A; Tokuda, K; Uchida, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Kimpara, I; Kudo, E; Kudo, H; Kudo, Y; Miura, T; Saitoh, Y; Sato, S; Tsujino, M	1
Kinoshita, S; Kumagai, S	1
Horii, T; Ichiyama, S; Kobayashi, M; Ohta, M	1
Hirata, Y; Hongo, T; Igari, J; Imafuku, Y; Inoue, M; Kawaguchi, R; Kobayashi, I; Kobayasi, Y; Kumasaka, K; Matsumoto, N; Nakasaki, N; Nishino, T; Oguri, T; Ohtaki, Y; Okada, J; Saeki, H; Sasaki, T; Satou, S; Shibano, T; Takahashi, A; Tokuda, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Arita, K; Daido, K; Kohara, T; Nakamura, K; Ohashi, N; Takeshima, Y	1
Hanaki, H; Hiramatsu, K	1
Murase, M	1
Fujimura, S; Gomi, K; Honda, Y; Kikuchi, T; Kobayashi, T; Nukiwa, T; Shoji, S; Takahashi, H; Tokue, Y; Watanabe, A; Yasui, S	1
Deguchi, K; Endo, H; Ishihara, R; Matsumoto, Y; Nishinari, C; Suzuki, Y	1
Aoki, N; Hashimoto, T; Hirata, Y; Hongo, T; Igari, J; Imafuku, Y; Inoue, M; Ishigo, S; Kajimura, K; Kawaguchi, R; Kobayashi, I; Kobayashi, Y; Kumasaka, K; Matsumoto, N; Matsuoka, K; Murakami, E; Nakasaki, N; Nishino, T; Oguri, T; Ohba, Y; Ohtaki, Y; Okada, J; Okamoto, E; Ono, J; Saeki, H; Sasaki, T; Satou, S; Shibano, T; Takahashi, A; Takata, T; Tokuda, K; Uehara, N; Watanabe, N; Yomoda, S; Yoshida, H	1
Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T	1
Inoue, M; Matsuda, K	1
Endo, H; Jinbo, K; Nishinari, C; Suzuki, Y; Tamura, C	1
Hikida, M; Inoue, M; Okamoato, R; Sato, Y; Terashima, S	1
Araake, M; Gotoh, N; Hiraishi, T; Miyata, A; Nishino, T; Ogawa, H; Takata, T	1
Chinzei, T; Ishida, A; Tasaka, K	1
Abe, T; Fukuoka, T; Inoue, M; Ishii, C; Kakuta, M	1
Furugo, I; Ishida, M; Takii, M; Ueda, M	1
Hashimoto, H; Horii, T; Kanno, T; Maekawa, M; Morita, M; Muramatsu, H	1
Hashimoto, K; Ito, K; Ogata, H	1
Sakata, H	2
Abe, K; Arai, T; Hasebe, N; Horiuchi, M; Kimura, M; Tokumura, M	1
Joo, JY; Kim, JH; Kwon, OH; Lee, SG	1
Shah, PM	1
Hori, S; Kizu, J; Kurihara, Y	1
Hino, M; Kanamaru, A; Masaoka, T; Nakagawa, Y; Ohta, K; Ohyashiki, K; Suzuki, K; Tamura, K; Urabe, A	1
Chen, Y; Du, X; Fu, Y; Ji, J; Wang, H; Yu, Y	1

Reviews

1 review(s) available for panipenem and meropenem

Article	Year
Parenteral carbapenems. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2008, Volume: 14 Suppl 1 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Ertapenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Humans; Imipenem; Infusions, Parenteral; Meropenem; Thienamycins	2008

Article

Year

Parenteral carbapenems.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2008, Volume: 14 Suppl 1

Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Ertapenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Humans; Imipenem; Infusions, Parenteral; Meropenem; Thienamycins

2008

Trials

1 trial(s) available for panipenem and meropenem

Article	Year
Prospective randomized study of cefepime, panipenem, or meropenem monotherapy for patients with hematological disorders and febrile neutropenia. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Female; Fever; Hematologic Diseases; Humans; Male; Meropenem; Neutropenia; Prospective Studies; Thienamycins; Treatment Outcome; Young Adult	2013

Article

Year

Prospective randomized study of cefepime, panipenem, or meropenem monotherapy for patients with hematological disorders and febrile neutropenia.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:1

Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Female; Fever; Hematologic Diseases; Humans; Male; Meropenem; Neutropenia; Prospective Studies; Thienamycins; Treatment Outcome; Young Adult

2013

Other Studies

38 other study(ies) available for panipenem and meropenem

Article	Year
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Carbapenems; Doripenem; Meropenem; Microbial Sensitivity Tests; Thienamycins	2009
Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Adolescent; Adult; Aged; Bacterial Capsules; Child; Child, Preschool; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Polymerase Chain Reaction; Streptococcus agalactiae	2009
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship	2009
Promising new carbapenem antibiotics for treatment of neonatal meningitis due to Campylobacter fetus. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1995, Volume: 69, Issue:7 Topics: Campylobacter fetus; Campylobacter Infections; Drug Resistance, Microbial; Humans; Infant, Newborn; Meningitis, Bacterial; Meropenem; Thienamycins	1995
Structural features resulting in convulsive activity of carbapenem compounds: effect of C-2 side chain. The Journal of antibiotics, 1995, Volume: 48, Issue:5 Topics: Animals; Imipenem; Meropenem; Mice; Mice, Inbred ICR; Receptors, GABA; Seizures; Structure-Activity Relationship; Thienamycins	1995
[Influence of urine pH and cations on antimicrobial activities of penems]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1993, Volume: 67, Issue:5 Topics: Cations, Divalent; Escherichia coli; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Pseudomonas aeruginosa; Thienamycins; Urinary Tract Infections; Urine	1993
Effects of a beta-lactamase inhibitor, sulbactam, on the activity of carbapenems against Pseudomonas aeruginosa. The Journal of antibiotics, 1995, Volume: 48, Issue:11 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Drug Synergism; Enzyme Inhibitors; Imipenem; Meropenem; Pseudomonas aeruginosa; Sulbactam; Thienamycins	1995
[Antimicrobial activities of meropenem against clinically isolated strains. The result against strains isolated from blood and cerebrospinal fluid]. The Japanese journal of antibiotics, 1996, Volume: 49, Issue:4 Topics: Ampicillin; Blood; Cefotaxime; Cephalosporins; Cerebrospinal Fluid; Escherichia coli; Humans; Imipenem; Listeria monocytogenes; Meningitis, Bacterial; Meropenem; Penicillins; Sepsis; Streptococcus agalactiae; Streptococcus pneumoniae; Thienamycins	1996
Structure-activity relationships of carbapenem compounds to anti-Haemophilus influenzae activity and affinity for penicillin-binding proteins. Effect of 1 beta-methyl group and C-2 side chain. The Journal of antibiotics, 1997, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Carbapenems; Carrier Proteins; Haemophilus influenzae; Hexosyltransferases; Imipenem; Meropenem; Methylation; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Binding; Structure-Activity Relationship; Thienamycins	1997
[Survey of sensitivities of clinical isolates to antibacterial agents (annual report)]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:8 Topics: 4-Quinolones; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Carbapenems; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Cocci; Haemophilus influenzae; Humans; Imipenem; Meropenem; Monobactams; Penicillins; Pseudomonas aeruginosa; Serratia marcescens; Thienamycins	1997
[In vitro combination effect of vancomycin and carbapenems against carbapenem-resistant MRSA]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:8 Topics: Anti-Bacterial Agents; Carbapenems; Imipenem; Meropenem; Methicillin Resistance; Staphylococcus aureus; Thienamycins; Vancomycin	1997
[Antimicrobial activity of carbapenem antibiotics against gram-negative bacilli]. The Japanese journal of antibiotics, 1998, Volume: 51, Issue:9 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Carbapenems; Cefozopran; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Imipenem; Meropenem; Monobactams; Norfloxacin; Tetracycline; Thienamycins	1998
Relationship between morphological changes and endotoxin release induced by carbapenems in Pseudomonas aeruginosa. Journal of medical microbiology, 1999, Volume: 48, Issue:3 Topics: Carbapenems; Endotoxins; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	1999
[Survey of the sensitivities of clinical isolates to antibacterial agents (annual report)]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:4 Topics: Carbapenems; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins; Time Factors	1999
[Study on antibiotics susceptibility and mechanism of carbapenem-resistance in clinical isolates of Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:7 Topics: Anti-Infective Agents; beta-Lactam Resistance; Carbapenems; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Ofloxacin; Pseudomonas aeruginosa; Thienamycins	1999
[Combination effect of teicoplanin and various antibiotics against hetero-VRSA and VRSA]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1999, Volume: 73, Issue:10 Topics: Anti-Bacterial Agents; Drug Synergism; Drug Therapy, Combination; Imipenem; Meropenem; Methicillin Resistance; Staphylococcus aureus; Teicoplanin; Thienamycins; Vancomycin Resistance	1999
[In vitro antibacterial activities of carbapenems against clinical isolates]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:11 Topics: Bacteria; Enterobacteriaceae; Imipenem; Meropenem; Methicillin Resistance; Pseudomonas aeruginosa; Staphylococcus aureus; Thienamycins	1999
[In vitro activity of biapenem (BIPM) against clinically isolated respiratory pathogens in 1996-1998]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:12 Topics: Bacteria; Carbapenems; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Imipenem; Meropenem; Penicillins; Piperacillin; Respiratory Tract Infections; Thienamycins; Time Factors	1999
[Antimicrobial activities of meropenem against clinically isolated strains in 1997]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:12 Topics: Bacteria; Carbapenems; Cephalosporins; Drug Resistance, Microbial; Humans; Imipenem; Meropenem; Thienamycins; Time Factors	1999
[Changes in the antibacterial activity of chemotherapeutic agents (especially carbapenems) for 10 species of clinical isolates between 1994 and 1996. Surveillance group of the sensitivities of clinical isolates to antibacterial agents]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:3 Topics: Bacteria; Carbapenems; Drug Resistance, Microbial; Humans; Imipenem; Japan; Meropenem; Multicenter Studies as Topic; Thienamycins; Time Factors	2000
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12 Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins	2000
[Evaluation of antibiotics by the method of initial bactericidal activity]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12 Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins	2000
[Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:9 Topics: Bacteria; Carbapenems; Cefepime; Cefozopran; Cephalosporins; Imipenem; Meropenem; Thienamycins	2001
[Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:11 Topics: beta-Lactamases; Carbapenems; Drug Resistance, Microbial; Imipenem; Meropenem; Pseudomonas aeruginosa; Thienamycins	2001
[Bactericidal activity of biapenem against various efflux system mutants of Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:1 Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Imipenem; Meropenem; Mutation; Pseudomonas aeruginosa; Thienamycins	2002
[Antimicrobial activity of carbapenems and the combined effect with aminoglycoside against recent clinical isolates of Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:2 Topics: Amikacin; Anti-Bacterial Agents; Carbapenems; Drug Synergism; Drug Therapy, Combination; Imipenem; Meropenem; Pseudomonas aeruginosa; Thienamycins	2002
[Rapid bactericidal activities of carbapenems against Pseudomonas aeruginosa in simulating human plasma concentrations]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:2 Topics: Carbapenems; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Microscopy, Electron, Scanning; Models, Biological; Pseudomonas aeruginosa; Thienamycins	2002
[Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Adult; Aged; Ampicillin; Anti-Infective Agents; beta-Lactamases; Cefaclor; Cephalosporins; Child, Preschool; Female; Haemophilus influenzae; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Respiratory System; Seasons; Sulbactam; Thienamycins	2002
Effect of basic amino acids on susceptibility to carbapenems in clinical Pseudomonas aeruginosa isolates. International journal of medical microbiology : IJMM, 2003, Volume: 293, Issue:2-3 Topics: Amino Acids, Basic; Anti-Bacterial Agents; Aztreonam; Carbapenems; Ceftazidime; Culture Media; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa; Thienamycins	2003
[Activity of cephems and carbapenems against clinically isolated Mycobacterium abscessus]. Kekkaku : [Tuberculosis], 2003, Volume: 78, Issue:9 Topics: Carbapenems; Cefoxitin; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Thienamycins; Tuberculosis, Pulmonary	2003
[Antimicrobial susceptibilities of Streptococcus pneumoniae and Haemophilus influenzae isolated from children with meningitis]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2004, Volume: 78, Issue:1 Topics: Ampicillin; Cefotaxime; Ceftriaxone; Child, Preschool; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Infant; Meningitis; Meropenem; Streptococcus pneumoniae; Thienamycins; Vancomycin	2004
Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics. Toxicology, 2006, May-01, Volume: 222, Issue:1-2 Topics: Alanine; Animals; Anti-Bacterial Agents; Anticonvulsants; Carbapenems; Convulsants; Dogs; Doripenem; Drug Interactions; Electroencephalography; Injections, Intravenous; Injections, Intraventricular; Male; Meropenem; Mice; Mice, Inbred ICR; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Thienamycins; Valproic Acid	2006
[Relationship between protein binding and antimicrobial activities of antibiotics against Streptococcus pneumoniae and Haemophilus influenzae]. The Japanese journal of antibiotics, 2006, Volume: 59, Issue:5 Topics: Administration, Oral; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Child; Haemophilus influenzae; Humans; Injections, Intravenous; Meropenem; Microbial Sensitivity Tests; Protein Binding; Streptococcus pneumoniae; Thienamycins	2006
[Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics]. The Korean journal of laboratory medicine, 2007, Volume: 27, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticonvulsants; Carbapenems; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Imipenem; Male; Meropenem; Middle Aged; Thienamycins; Valproic Acid	2007
Simple and rapid determination of serum carbapenem concentrations by high-performance liquid chromatography. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2008, Volume: 14, Issue:1 Topics: Animals; Anti-Bacterial Agents; Carbapenems; Chromatography, High Pressure Liquid; Imipenem; Male; Meropenem; Mice; Thienamycins	2008
In vitro activity of sulbactam in combination with imipenem, meropenem, panipenem or cefoperazone against clinical isolates of Acinetobacter baumannii. International journal of antimicrobial agents, 2013, Volume: 41, Issue:4 Topics: Acinetobacter baumannii; Acinetobacter Infections; beta-Lactams; Cefoperazone; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Sulbactam; Thienamycins	2013