pamidronate and olpadronic acid

pamidronate has been researched along with olpadronic acid in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's15 (48.39)18.2507
2000's12 (38.71)29.6817
2010's3 (9.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey, BN; Caldera, A; Croft, SL; Docampo, R; Grimley, JS; Heath, HT; Kendrick, H; Lewis, JC; Lira, R; Martin, MB; Moreno, SN; Oldfield, E; Urbina, JA; Yardley, V1
Burzynska, A; Croft, SL; de Luca-Fradley, K; Grimley, JS; Kafarski, P; Kendrick, H; Lewis, JC; Martin, MB; Meints, GA; Oldfield, E; Olsen, JR; Sanders, JM; Van Brussel, EM1
Bachmann, R; Bisping, M; Born, AR; Cortesi, R; Glatt, M; Green, JR; Guiglia, G; Jaeggi, KA; Jeker, H; Klein, R; Müller, K; Ramseier, U; Schmid, J; Schreiber, G; Seltenmeyer, Y; Widler, L1
Bruchhaus, I; Chan, JM; Croft, SL; Flessner, RM; Ghosh, S; Kemp, RG; Kendrick, H; Kobayashi, S; Lea, CR; Lewis, JC; Loftus, TC; Meints, GA; Nozaki, T; Oldfield, E; Tovian, ZS1
Burzynska, A; Chan, JM; Colantino, A; Ghosh, S; Kafarski, P; Meints, G; Morita, CT; Oldfield, E; Raker, AM; Sanders, JM; Song, Y; Wang, H1
Craig, SP; Delfino, JM; Fernández, D; Wenck, MA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Alblas, MJ; Bijvoet, OL; de Groot, H; Löwik, CW; Papapoulos, SE; van der Pluijm, G; van der Wee-Pals, LJ1
Hoekman, K; Papapoulos, SE; Tjandra, YI1
Keppler, BK; Klenner, T; Krempien, B; Schmähl, D; Wingen, F1
Breedveld, FC; Lafeber, GJ; Markusse, HM1
Bijvoet, OL; Hoekman, K; Löwik, CW; Papapoulos, SE; Vermeij, P1
Mautalen, C; Pérez Lloret, A; Roldán, EJ; Vega, E1
Bijvoet, OL; Papapoulos, SE; Schweitzer, DH; Vermeij, P; Zwinderman, AH1
den Hartigh, J; Sparidans, RW; Vermeij, P1
Löwik, C; Papapoulos, S; Que, I; Van Beek, E1
Brown, RJ; Löwik, CW; Papapoulos, SE; van Beek, E; Watts, DJ1
Mondelo, N; Montuori, E; Parma, MD; Peluffo, VA; Piccinni, E; Zanchetta, JR1
González, D; Mautalen, C; Pastrana, M1
Cohen, L; Löwik, C; Papapoulos, S; Pieterman, E; van Beek, E1
Haber, B; Sentongo, TA1
Den Hartigh, J; Pas, O; Ramp-Koopmanschap, W; Twiss, IM; Vermeij, P1
Bellido, T; Manolagas, SC; Parfitt, AM; Plotkin, LI; Roberson, PK; Weinstein, RS1
Berenson, J; Hortobagyi, G; Lipton, A; Major, PP1
Mautalen, CA; Oliveri, MB; Parisi, MS1
Bellido, T; Leoni, J; Mathov, I; Plotkin, LI; Sgarlata, CL1
Gomez-Acotto, C; Mautalen, C; Zeni, S1
Bosch, JJ; Burggraaf, J; Cohen, AF; de Kam, ML; Twiss, IM; van den Berk, AH; Vermeij, P1
Burton, DW; Deftos, LJ; Geller, J; Hastings, RH; Hillegonds, DJ; Hoffman, RM; Yang, M1
de Jong, E; Hamdy, NA; Kuijpers, SC; van Merkesteyn, JP1
Roldán, EJ1

Reviews

1 review(s) available for pamidronate and olpadronic acid

ArticleYear
Oral bisphosphonates: A review of clinical use in patients with bone metastases.
    Cancer, 2000, Jan-01, Volume: 88, Issue:1

    Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid

2000

Trials

2 trial(s) available for pamidronate and olpadronic acid

ArticleYear
Preliminary study of multiple increasing oral doses of dimethyl-APD on bone metabolism dynamics and safety profile.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:3

    Topics: Aged; Alkaline Phosphatase; Body Temperature; Bone and Bones; Calcium; Diphosphonates; Ergocalciferols; Humans; Hydroxyproline; Male; Middle Aged; Osteitis Deformans; Pamidronate; Tablets, Enteric-Coated

1994
A comparison of the gastrointestinal effects of the nitrogen-containing bisphosphonates pamidronate, alendronate, and olpadronate in humans.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:4

    Topics: Adult; Alendronate; Bone Density Conservation Agents; Cross-Over Studies; Diphosphonates; Female; Gastrointestinal Diseases; Humans; Pamidronate; Single-Blind Method

2006

Other Studies

28 other study(ies) available for pamidronate and olpadronic acid

ArticleYear
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Diphosphonates; Leishmania donovani; Plasmodium falciparum; Structure-Activity Relationship; Toxoplasma; Trypanosoma brucei brucei; Trypanosoma cruzi; Vero Cells

2001
Activity of bisphosphonates against Trypanosoma brucei rhodesiense.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Animals; Crystallography, X-Ray; Diphosphonates; Humans; Lethal Dose 50; Models, Molecular; Quantitative Structure-Activity Relationship; Quantum Theory; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Tumor Cells, Cultured

2002
Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Bone Resorption; Calcitriol; Diphosphonates; Hypercalcemia; Imidazoles; In Vitro Techniques; Kidney; Mice; Pamidronate; Parathyroidectomy; Rats; Skull; Structure-Activity Relationship; Thyroidectomy; Zoledronic Acid

2002
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Antimalarials; Antiprotozoal Agents; Cell Line; Cricetinae; Diphosphonates; Entamoeba histolytica; Entamoebiasis; Humans; In Vitro Techniques; Liver Abscess; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship

2004
Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates.
    Journal of medicinal chemistry, 2004, Jan-15, Volume: 47, Issue:2

    Topics: Alkyl and Aryl Transferases; Animals; Cell Division; Cell Line; Diphosphonates; Geranyltranstransferase; Humans; Leishmania major; Lymphocyte Activation; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Tumor Necrosis Factor-alpha

2004
The purine transferase from Trypanosoma cruzi as a potential target for bisphosphonate-based chemotherapeutic compounds.
    Bioorganic & medicinal chemistry letters, 2004, Sep-06, Volume: 14, Issue:17

    Topics: Animals; Diphosphonates; Drug Delivery Systems; Pentosyltransferases; Trypanosoma cruzi

2004
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Modulation of PTH-stimulated osteoclastic resorption by bisphosphonates in fetal mouse bone explants.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:11

    Topics: Animals; Bone Resorption; Calcium; Clodronic Acid; Culture Techniques; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mice, Inbred Strains; Pamidronate; Parathyroid Hormone; Pregnancy

1991
The role of 1,25-dihydroxyvitamin D in the maintenance of hypercalcemia in a patient with an ovarian carcinoma producing parathyroid hormone-related protein.
    Cancer, 1991, Aug-01, Volume: 68, Issue:3

    Topics: Aged; Bone Resorption; Calcitriol; Calcium; Diphosphonates; Female; Humans; Hypercalcemia; Ovarian Neoplasms; Pamidronate; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone-Related Protein; Proteins

1991
Anticancer-agent-linked phosphonates with antiosteolytic and antineoplastic properties: a promising perspective in the treatment of bone-related malignancies?
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:4

    Topics: Animals; Bone and Bones; Bone Neoplasms; Carcinoma 256, Walker; Diphosphonates; Drug Evaluation, Preclinical; Organophosphorus Compounds; Organoplatinum Compounds; Osteosarcoma; Pamidronate; Rats

1990
Bisphosphonates in collagen arthritis.
    Rheumatology international, 1990, Volume: 9, Issue:6

    Topics: Animals; Antibodies; Arthritis; Collagen; Diphosphonates; Female; Pamidronate; Radiography; Rats; Rats, Inbred Strains

1990
Application of an in vitro model and a clinical protocol in the assessment of the potency of a new bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:5

    Topics: Administration, Oral; Aged; Animals; Bone and Bones; Bone Resorption; Clinical Protocols; Diphosphonates; Humans; Hydroxyproline; Infusions, Intravenous; Mice; Middle Aged; Models, Biological; Organ Culture Techniques; Osteitis Deformans; Pamidronate; Prospective Studies

1989
Improved treatment of Paget's disease with dimethylaminohydroxypropylidene bisphosphonate.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993, Volume: 8, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bone Resorption; Diphosphonates; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Male; Middle Aged; Osteitis Deformans; Pamidronate; Remission Induction

1993
High-performance ion-exchange chromatography with in-line complexation of bisphosphonates and their quality control in pharmaceutical preparations.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:12

    Topics: Chromatography, Ion Exchange; Copper; Diphosphonates; Pamidronate; Potentiometry; Quality Control; Spectrophotometry, Ultraviolet; Tablets

1995
Dissociation of binding and antiresorptive properties of hydroxybisphosphonates by substitution of the hydroxyl with an amino group.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1996, Volume: 11, Issue:10

    Topics: Amines; Analysis of Variance; Animals; Binding Sites; Bone Matrix; Bone Resorption; Calcium Oxalate; Crystallization; Diphosphonates; Etidronic Acid; Female; Mice; Pamidronate; Pregnancy; Structure-Activity Relationship

1996
Differential effects of aminosubstituted analogs of hydroxy bisphosphonates on the growth of Dictyostelium discoideum.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:2

    Topics: Amines; Animals; Bone Density; Bone Resorption; Dictyostelium; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Female; Hindlimb; Mice; Pamidronate; Structure-Activity Relationship

1998
[Experimental effects of olpadronate and pamidronate on bone mass].
    Medicina, 1997, Volume: 57 Suppl 1

    Topics: Analysis of Variance; Animals; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Diphosphonates; Female; Male; Ovariectomy; Pamidronate; Rats; Rats, Wistar

1997
[Treatment of Paget's disease with olpadronate. Its efficacy in partial responders to oral pamidronate].
    Medicina, 1997, Volume: 57 Suppl 1

    Topics: Aged; Diphosphonates; Drug Tolerance; Female; Humans; Male; Osteitis Deformans; Pamidronate; Retrospective Studies; Treatment Outcome

1997
Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.
    Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2

    Topics: Animals; Bone Resorption; Brain; Carbon-Carbon Double Bond Isomerases; Cattle; Clodronic Acid; Dimethylallyltranstransferase; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hemiterpenes; Ibandronic Acid; Mice; Multienzyme Complexes; Nitrogen; Pamidronate

1999
Progress in the prevention and treatment of osteoporosis in pediatrics.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:3

    Topics: Adolescent; Bone Density; Child; Diphosphonates; Humans; Osteoporosis; Pamidronate

1999
The effects of nitrogen-containing bisphosphonates on human epithelial (Caco-2) cells, an in vitro model for intestinal epithelium.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1999, Volume: 14, Issue:5

    Topics: Alendronate; Apoptosis; Caco-2 Cells; Calcium; Cell Survival; Diphosphonates; Epithelial Cells; Humans; Intestinal Mucosa; Models, Biological; Nitrogen; Pamidronate; Solubility; Structure-Activity Relationship

1999
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:10

    Topics: Alendronate; Animals; Apoptosis; Calcitonin; Cell Line; Cells, Cultured; Dexamethasone; Diphosphonates; Etidronic Acid; Etoposide; In Situ Nick-End Labeling; Mice; Osteoblasts; Osteocytes; Pamidronate; Prednisolone; Skull; Tumor Necrosis Factor-alpha

1999
Bone mineral density response to long-term bisphosphonate therapy in fibrous dysplasia.
    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2001,Summer, Volume: 4, Issue:2

    Topics: Absorptiometry, Photon; Adult; Bone Density; Diphosphonates; Female; Fibrous Dysplasia, Polyostotic; Humans; Pamidronate; Time Factors

2001
Extracellular signal-regulated kinases and calcium channels are involved in the proliferative effect of bisphosphonates on osteoblastic cells in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:11

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cell Division; Cell Line; Cells, Cultured; Diphosphonates; Enzyme Activation; Etidronic Acid; Kinetics; Mitogen-Activated Protein Kinases; Nifedipine; Osteoblasts; Pamidronate; Phosphorylation; Rats

2001
Do different aminobisphosphonates have similar preventive effect on experimental thyroid hormone-induced osteopenia in rats?
    Calcified tissue international, 2001, Volume: 69, Issue:5

    Topics: Alendronate; Animals; Body Weight; Bone Diseases, Metabolic; Diphosphonates; Female; Pamidronate; Rats; Rats, Sprague-Dawley; Thyroxine

2001
The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Apr-15, Volume: 12, Issue:8

    Topics: Animals; Bone Density Conservation Agents; Bone Neoplasms; Calcium; Cell Line, Tumor; Diphosphonates; Disease Progression; Glycoproteins; Green Fluorescent Proteins; Humans; Male; Mice; Mice, Nude; Osteoprotegerin; Pamidronate; Parathyroid Hormone-Related Protein; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Time Factors; Treatment Outcome; Xenograft Model Antitumor Assays

2006
Initial results of the treatment of diffuse sclerosing osteomyelitis of the mandible with bisphosphonates.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2011, Volume: 39, Issue:1

    Topics: Adult; Aged; Analgesics; Bone Density Conservation Agents; Child; Diphosphonates; Female; Follow-Up Studies; Humans; Imidazoles; Injections, Intravenous; Male; Mandibular Diseases; Middle Aged; Osteomyelitis; Pamidronate; Radionuclide Imaging; Recurrence; Sclerosis; Treatment Outcome; Young Adult; Zoledronic Acid

2011
[Pamidronate and olpadronate discoverer, Prof. Olav Maria Leonard Bijvoet passed away].
    Medicina, 2014, Volume: 74, Issue:5

    Topics: Bone Density Conservation Agents; Diphosphonates; History, 20th Century; History, 21st Century; Pamidronate

2014