pamidronate and clodronic acid

pamidronate has been researched along with clodronic acid in 164 studies

Research

Studies (164)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (10.37)	18.7374
1990's	52 (31.71)	18.2507
2000's	65 (39.63)	29.6817
2010's	27 (16.46)	24.3611
2020's	3 (1.83)	2.80

Authors

Authors	Studies
Guogas, LM; Lujan, SA; Matson, SW; Ragonese, H; Redinbo, MR	1
Lecouvey, M; Monteil, M; Puljula, E; Turhanen, P; Vepsäläinen, J; Weisell, J	1
Almeida Paz, FA; Barbosa, JS; Braga, SS	1
Geldof, AA; Newling, DW; Rao, BR; Sun, YC	1
Mönkkönen, J; van Rooijen, N; Ylitalo, P	1
Coleman, RE	3
Bauss, F; Bosies, E; Fleisch, H; Janner, M; Mühlbauer, RC; Schenk, R; Strein, K	1
Alblas, MJ; Bijvoet, OL; de Groot, H; Löwik, CW; Papapoulos, SE; van der Pluijm, G; van der Wee-Pals, LJ	1
Chambers, TJ; Flanagan, AM	1
Boyle, IT; Dryburgh, FJ; Fraser, WD; Gallacher, SJ; Patel, U; Ralston, SH	1
Koponen, HM; Mönkkönen, J; Ylitalo, P	1
Warrell, RP	2
Dandona, P; Khokher, MA	1
Gowen, M; Hughes, DE; MacDonald, BR; Russell, RG	1
Boyle, IT; Cowan, RA; Dryburgh, FJ; Fraser, WD; Gallacher, SJ; Patel, U; Ralston, SH	1
Coleman, RE; Rubens, RD	1
Bijvoet, OL; Blanksma, HJ; Dahlinghaus-Nienhuys, PJ; Harinck, HI	1
Bijvoet, OL; Bloys van Treslong-de Groot, H; Boonekamp, PM; Löwik, CW; van de Pluym, G; van de Wee-Pals, L	1
Larsson, A; Lerner, UH	1
Simmelink, JW	1
Delaissé, JM; Eeckhout, Y; Vaes, G	1
Petrovic, AG; Stutzmann, JJ	1
Fleisch, H	1
Bijvoet, OL; Cats, A; de Vries, E; Jager, MJ; Sleeboom, HP; van der Veen, CJ; van der Weij, JP; van Paassen, HC	1
Bornand, J; Edouard, C; Jung, A; Mermillod, B; Meunier, PJ	1
Delmas, PD; Meunier, PJ	1
Bijvoet, OL; Frijlink, WB; Reitsma, PH	1
Bijvoet, OL; de Vries, E; Frijlink, WB; Jie, K; Meijer, CJ; Mulder, H; Reitsma, PH; te Velde, J; van der Linden, H; van der Wey, JP; van Paassen, HC	1
Lehenkari, P; Selander, K; Väänänen, HK	1
Anthony, C; Coleman, RE; Kanis, JA; Purohit, OP; Radstone, CR	1
Auriola, SO; Mönkkönen, J; Taskinen, M; Urtti, A	1
Hyvönen, PM; Kowolik, MJ	1
Kiełbiński, M	1
Collin, P; Fleisch, H; Guenther, HL; Martin, TJ; Sahni, M	1
Ralston, SH	1
Meunier, PJ; Vignot, E	1
Kanis, JA	2
Hirvonen, MR; Makkonen, N; Mönkkönen, J; Savolainen, K; Teräväinen, T	1
Mönkkönen, J; Urtti, A; Ylitalo, P; Ylitalo, R	1
Burckhardt, P; Fioroni, P; Juillerat, L; Leuenberger, P; Ludwig, H; Markert, M; Pecherstorfer, M; Sauty, A; Thiebaud, D; Zimmer-Roth, I	1
Ashley, S; Hanson, J; Kanis, JA; McCloskey, E; Paterson, AH; Powles, TJ	1
Hannuniemi, R; Härkönen, P; Karhukorpi, EK; Mönkkönen, J; Selander, KS; Väänänen, HK	1
Coleman, RE; Eastell, R; Guo, CY; Purohit, OP; Vinholes, J	1
Bankhead, C	1
Licata, AA	1
Body, JJ; Coleman, RE; Piccart, M	1
Gupta, M; Smith, AD; Tuncay, OL; Valderrama, E	1
Adachi, H; Hirafuji, M; Igarashi, K; Mitani, H; Shinoda, H	1
Fleisch, HA	1
Strang, P	1
Jantunen, E; Laakso, M	1
Blomqvist, C; Elomaa, I	1
Ceponis, A; Ding, Y; Konttinen, YT; Lindy, O; López-Otín, C; Santavirta, S; Sorsa, T	1
Boissier, S; Clezardin, P; Cuzin, B; Delmas, PD; Ebetino, FH; Frappart, L; Magnetto, S	1
Apperley, JF; Croucher, PI; Rogers, MJ; Russell, RG; Shipman, CM	1
Burckhardt, P; Green, JR; Ibarra de Palacios, P; Kandra, A; Leuenberger, P; Sauty, A; Sitzler, L; Thiébaud, D; Zieschang, J	1
Berenson, JR	2
Lipton, A	3
Bloomfield, DJ	1
Kautiainen, S; Luurila, S; Ylitalo, P; Ylitalo, R	2
Kalliovalkama, J; Kankaanranta, H; Lähteenmäki, T; Pörsti, I; Salenius, JP; Sisto, T; Wu, X; Ylitalo, P; Ylitalo, R	1
Knowles, S; Phillips, E; Shear, NH; Weber, E	1
Diel, IJ	1
Bartl, R; Body, JJ; Burckhardt, P; Delmas, PD; Diel, IJ; Fleisch, H; Kanis, JA; Kyle, RA; Mundy, GR; Paterson, AH; Rubens, RD	1
Musto, P	1
Cohen, L; Löwik, C; Papapoulos, S; Pieterman, E; van Beek, E	1
Mundy, GR	1
Berthaud, P; Jadaud, E; Lortholary, A	1
Berenson, J; Hortobagyi, G; Lipton, A; Major, PP	1
Horn, E; Jilch, R; Keck, AV; Pecherstorfer, M; Sauty, A; Thiebaud, D; Zimmer-Roth, I	1
Arnett, TR; Colston, KW; Mansi, JL; Pirianov, G; Senaratne, SG	1
Brion, N; Clerc, D; Paule, B	1
Kanis, JA; McCloskey, EV	1
Body, JJ	1
Bastert, G; Diel, IJ; Solomayer, EF	2
Cundy, T; Zacharin, M	1
Body, JJ; Fromigue, O; Lagneaux, L	1
Alvarez, M; Arlet, P; Dingremont, C; Godfrin, B; Laroche, M; Ollier, S; Sailler, L	1
Bonabello, A; Bruzzese, T; Galmozzi, MR; Zara, GP	1
Watts, NB	1
Choong, PF; Fisher, JL; Mackie, PS; Zhou, H	1
Johnson, IS	1
Boos, J; Eckervogt, V; Sonnemann, J; Truckenbrod, B; van Valen, F; Winkelmann, W	2
Jones, J	1
Coleman, RE; Heatley, S; Herling, C; Jagdev, SP; Purohit, P	1
Mykała-Cieśla, J; Stajszczyk, M	1
Adam, Z	1
Wiffen, PJ; Wong, R	1
Body, JJ; Fromigué, O	1
Anderson, K; Berenson, JR; Biermann, JS; Hillner, BE; Kyle, RA; Lipton, A; Yee, GC	1
Allolio, B; Dettling, A; Fassnacht, M; Franke, A; Hahner, S; Wudy, S; Zink, M	1
Bowes, M; Chan, O; Fox, AJ; Glatt, M; Green, J; Kesingland, A; Kidd, BL; McNair, K; Medhurst, SJ; Patel, S; Urban, LA; Walker, K	1
Barthel, HR	1
Cook, R; Major, PP	1
Epstein, M; Joshua, F; Major, G	1
Saad, F	1
Hanemaaijer, R; Konttinen, YT; Mandelin, J; Mönkkönen, J; Salminen, A; Teronen, O; Valleala, H	1
Bonabello, A; Canaparo, R; Galmozzi, MR; Serpe, L; Zara, GP	1
Chow, E; Clemons, M; Enright, K	1
Adami, S; Crepaldi, G; Filipponi, P; Sartori, L	1
Atula, ST; Nevalainen, JI; Pylkkänen, LH; Tähtelä, RK	1
Ammann, P; Herter-Clavel, C; Lubrano, A; Rizzoli, R	1
Mossetti, G; Nunziata, V; Rendina, D; Sorrentino, M; Viceconti, R	1
Berenson, J; Hirschberg, R	1
Deangelis, C; Einarson, TR; Iscoe, N; Romanus, D; Shear, N	1
Forsea, AM; Geilen, CC; Müller, C; Orfanos, CE; Riebeling, C	1
Coleman, R; Conte, P	1
Boos, J; Lanvers-Kaminsky, C; Vorotnjak, M	1
Khuri, F; Saba, N	1
Butler, SL; Ganguli, A; Grant, MH; Lloyd, AW; Meikle, ST; Philips, GJ; Steward, C	1
Abrahamsen, B; Brixen, KT; Kassem, MS; Mosekilde, L	1
Gralow, J	1
Clemons, M; Verma, S	1
Balla, J	1
Lugassy, G	1
Azzarello, G; Balducci, E; Crepaldi, G; Dalle Carbonare, L; Giannini, S; Realdi, G; Valenti, MT; Vinante, O	1
Franke, HR; Verdijk, R; Vermes, I; Wolbers, F	1
Kuo, SW; Lee, IT; Pei, D; Sheu, WH; Tu, ST	1
Aerts, K; Bridts, CH; Cos, P; De Clerck, LS; De Tollenaere, CB; Dombrecht, EJ; Ebo, DG; Schuerwegh, AJ; Stevens, WJ; Van Offel, JF	1
Langdahl, B; Mosekilde, L; Vestergaard, P	1
Clemons, MJ; Cole, DE; Dranitsaris, G; Ooi, WS; Pritchard, KI; Sukovic, T; Trudeau, M; Verma, S; Wong, BY; Yogendran, G	1
Azzarello, G; Balducci, E; Bertoldo, F; Dalle Carbonare, L; Fracalossi, A; Lo Cascio, V; Valenti, MT; Vinante, O	1
Dulea, C; Gherase, A; Savu, SR; Silvestro, L; Tarcomnicu, I	1
Bauss, F; Haiker, M; Künkele, KP; Lühe, A; Pfister, T; Schad, K; Suter, L; Zihlmann, C	1
Alons, K; de Jong, E; Kuijpers, SC; van Merkesteyn, JP	1
Cruz, LS; Fonseca, M; Machado, M; Tannus, G	1
Al-Nawas, B; Brüllmann, D; Gauss, L; Kämmerer, P; Klein, MO; Pabst, A; Walter, C; Ziebart, T	1
Al-Nawas, B; Klein, M; Pabst, A; Walter, C; Ziebart, T	1
Deuber, HJ; Theiss, F	1
Jahanzeb, M; Mahtani, R	1
Rajkumar, SV	1
Al-Nawas, B; Koch, FP; Pabst, AM; Taylor, KY; Walter, C; Ziebart, T	1
Berenson, J; Dimopoulos, MA; Terpos, E	1
Ludwig, H; Zojer, N	1
Carson, DA; Cho, JS; Corr, M; Crain, B; Hayashi, T; Miller, LS; Norton, JT	1
Clark, OA; Djulbegovic, B; Glasmacher, A; Kumar, A; Mhaskar, R; Miladinovic, B; Redzepovic, J; Wheatley, K	1
Morgans, AK; Smith, MR	1
Cavo, M; Dimopoulos, MA; Drake, MT; Durie, BG; García-Sanz, R; Jurczyszyn, A; Leleu, X; Lentzsch, S; Merlini, G; Morgan, G; Munshi, N; Raje, N; Rajkumar, SV; Reiman, T; Roodman, GD; Sezer, O; Shimizu, K; Spencer, A; Terpos, E; Turesson, I	1
Ben-Aharon, I; Rizel, S; Shpilberg, O; Stemmer, SM; Sulkes, A; Vidal, L; Yerushalmi, R	1
Brown, J; Fullarton, JR; Palmieri, C	1
Alegre, A; Bailén, A; Giraldo, P; Gironella, M	1
Bouxsein, ML; Brooks, DJ; Demay, MB; Louis, L; Zhu, ED	1
Hagelauer, N; Pabst, AM; Ulbrich, H; Walter, C; Ziebart, T	1
Collavino, K; Delve, E; Lakhani, A; Rosa, RG; Rosenthal, AK; Waldman, SD; Weber, JF	1
Criscitiello, C; Curigliano, G; De Laurentiis, M; De Placido, S; Esposito, A; Gelao, L; Goldhirsch, A; Santangelo, M; Viale, G	1
De Luna-Bertos, E; García-Martínez, O; Manzano-Moreno, FJ; Ramos-Torrecillas, J; Ruiz, C	1
Jacobs, C; Krüger, M; Pabst, AM; Sagheb, K; Walter, C; Ziebart, T	1
Bartoszewicz, M; Gluza, K; Junka, A; Kos, M; Smutnicka, D; Szymczyk, P	1
Balbontín-Ayala, F; Cañigral, A; Carlos, Fd; Cobo, T; Fernández-González, FJ; Fernández-Vázquez, JP; Gonzalo-Orden, JM; Sánchez-Lasheras, F; Vega, JA	1
Mészaros, Á; Veszelyné Kotán, E	2
Djulbegovic, B; Kumar, A; Mhaskar, R; Miladinovic, B	1
Adams, A; Heidenreich, A; Jakob, T; Kuhr, K; Macherey, S; Monsef, I; Skoetz, N; Tesfamariam, YM	1
Bhardwaj, A; Sinha, NK; Swe, KMM	1

Reviews

59 review(s) available for pamidronate and clodronic acid

Article	Year
Bisphosphonates, Old Friends of Bones and New Trends in Clinics. Journal of medicinal chemistry, 2021, 02-11, Volume: 64, Issue:3 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Diseases; Diphosphonates; Drug Compounding; Drug Delivery Systems; Humans	2021
Hypercalcemia and bone metastases in breast cancer. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hypercalcemia; Neoplasm Proteins; Pamidronate; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factors	1990
Bone metastases and breast cancer. Cancer treatment reviews, 1985, Volume: 12, Issue:4 Topics: Alkaline Phosphatase; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium-Binding Proteins; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; Lymphokines; Osteocalcin; Osteogenesis; Pamidronate; Peptides; Prostaglandin Antagonists; Prostaglandins; Tomography, X-Ray Computed; Transforming Growth Factors	1985
[Biphosphonate as a therapeutic drug--experimental studies and clinical application]. Therapeutische Umschau. Revue therapeutique, 1985, Volume: 42, Issue:6 Topics: Animals; Calcinosis; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyroidism; Myositis Ossificans; Osteitis Deformans; Osteolysis; Osteoporosis; Pamidronate; Urinary Calculi	1985
[Pharmacologic therapy of bone tissue changes due to hematologic malignancies and bone metastasis]. Acta haematologica Polonica, 1994, Volume: 25, Issue:2 Topics: Bone Neoplasms; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasms; Osteolysis; Osteosclerosis; Pamidronate	1994
Pathogenesis and management of cancer associated hypercalcaemia. Cancer surveys, 1994, Volume: 21 Topics: Antineoplastic Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Diuretics; Etidronic Acid; Fluid Therapy; Gallium; Humans; Hypercalcemia; Neoplasms; Pamidronate; Phosphates; Plicamycin; Research	1994
Bone and cancer: pathophysiology and treatment of metastases. Bone, 1995, Volume: 17, Issue:2 Suppl Topics: Analgesics, Non-Narcotic; Bone and Bones; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Double-Blind Method; Female; Fractures, Bone; Humans; Hypercalcemia; Pain; Pamidronate; Parathyroid Hormone	1995
Bisphosphonate therapy. The American journal of the medical sciences, 1997, Volume: 313, Issue:1 Topics: Alendronate; Animals; Bone Density; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid	1997
Use of bisphosphonates in cancer patients. Cancer treatment reviews, 1996, Volume: 22, Issue:4 Topics: Alendronate; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Osteolysis; Pain; Pamidronate; Structure-Activity Relationship	1996
Bisphosphonates: preclinical aspects and use in osteoporosis. Annals of medicine, 1997, Volume: 29, Issue:1 Topics: Alendronate; Animals; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Osteoporosis; Pamidronate	1997
Analgesic effect of bisphosphonates on bone pain in breast cancer patients: a review article. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Analgesia; Analgesics, Non-Narcotic; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Humans; Osteoclasts; Pain; Pamidronate	1996
Bisphosphonate therapy in multiple myeloma. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Humans; Multiple Myeloma; Pamidronate	1996
Rationale for the use of bisphosphonates in breast cancer. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Bone Neoplasms; Bone Remodeling; Breast Neoplasms; Clodronic Acid; Cost-Benefit Analysis; Diphosphonates; Fractures, Spontaneous; Humans; Hypercalcemia; Osteoclasts; Pain; Pamidronate; Quality of Life	1996
Bisphosphonate therapy in metastatic breast cancer. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Humans; Pamidronate	1996
Bisphosphonates in multiple myeloma. Cancer, 1997, Oct-15, Volume: 80, Issue:8 Suppl Topics: Bone Diseases; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Multiple Myeloma; Pain; Pamidronate; Randomized Controlled Trials as Topic	1997
Bisphosphonates and breast carcinoma. Cancer, 1997, Oct-15, Volume: 80, Issue:8 Suppl Topics: Bone Diseases; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcification, Physiologic; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; Pain; Pamidronate; Treatment Outcome	1997
Should bisphosphonates be part of the standard therapy of patients with multiple myeloma or bone metastases from other cancers? An evidence-based review. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:3 Topics: Analgesics, Non-Narcotic; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Evidence-Based Medicine; Female; Humans; Male; Multiple Myeloma; Pain; Pamidronate; Practice Guidelines as Topic; Prostatic Neoplasms; Randomized Controlled Trials as Topic	1998
Aredia: the once-monthly infusion for the treatment of bone metastases. Current opinion in oncology, 1998, Volume: 10 Suppl 1 Topics: Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Drug Administration Schedule; Etidronic Acid; Female; Humans; Male; Multiple Myeloma; Osteoclasts; Pamidronate; Randomized Controlled Trials as Topic	1998
[Bisphosphonates in the adjuvant therapy of breast cancer-- pathophysiology, animal models, and clinical experiences]. Gynakologisch-geburtshilfliche Rundschau, 1998, Volume: 38, Issue:2 Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Pamidronate; Rats	1998
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12 Topics: Analgesics, Non-Narcotic; Bone and Bones; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Multiple Myeloma; Pain; Pamidronate	1998
The role of bisphosphonates for the treatment of bone disease in multiple myeloma. Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6 Topics: Adult; Aged; Aged, 80 and over; Bone Remodeling; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; Hypercalcemia; Male; Middle Aged; Multicenter Studies as Topic; Multiple Myeloma; Osteolysis; Palliative Care; Pamidronate; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome	1998
Bisphosphonates as cancer drugs. Hospital practice (1995), 1999, May-15, Volume: 34, Issue:5 Topics: Antineoplastic Agents; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Neoplasm Proteins; Neoplasms; Osteolysis; Pamidronate; Parathyroid Hormone-Related Protein; Proteins; Risedronic Acid; Transforming Growth Factor beta	1999
[Bisphosphonates and bone metastases]. Bulletin du cancer, 1999, Volume: 86, Issue:9 Topics: Antineoplastic Agents; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Male; Multiple Myeloma; Pain; Pamidronate; Prostatic Neoplasms; Randomized Controlled Trials as Topic	1999
Oral bisphosphonates: A review of clinical use in patients with bone metastases. Cancer, 2000, Jan-01, Volume: 88, Issue:1 Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid	2000
Bisphosphonates in multiple myeloma. Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl Topics: Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Multiple Myeloma; Pain; Pamidronate	2000
Current and future directions in medical therapy: hypercalcemia. Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Neoplasms; Pamidronate; Zoledronic Acid	2000
Bisphosphonates and the prevention of metastasis: first evidences from preclinical and clinical studies. Cancer, 2000, Jun-15, Volume: 88, Issue:12 Suppl Topics: Animals; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Pamidronate	2000
Treatment of osteoporosis with bisphosphonates. Rheumatic diseases clinics of North America, 2001, Volume: 27, Issue:1 Topics: Aged; Alendronate; Bone and Bones; Bone Density; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid	2001
Treatment of metastatic bone disease in breast cancer: bisphosphonates. Clinical breast cancer, 2000, Volume: 1, Issue:1 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Spontaneous; Humans; Hypercalcemia; Incidence; Pain; Pamidronate; Patient Selection; Survival Analysis; Treatment Outcome	2000
[Bisphosphonates in the treatment of breast carcinoma]. Polskie Archiwum Medycyny Wewnetrznej, 2001, Volume: 106, Issue:2 Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Pamidronate; Zoledronic Acid	2001
Bisphosphonates for the relief of pain secondary to bone metastases. The Cochrane database of systematic reviews, 2002, Issue:2 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Pain; Pamidronate; Randomized Controlled Trials as Topic	2002
Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints. American journal of clinical oncology, 2002, Volume: 25, Issue:6 Suppl 1 Topics: Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Data Interpretation, Statistical; Diphosphonates; Female; Fractures, Spontaneous; Humans; Hypercalcemia; Imidazoles; Male; Models, Statistical; Pain; Pamidronate; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Spinal Cord Compression; Treatment Outcome; Zoledronic Acid	2002
Treatment of hypercalcemia of malignancy with bisphosphonates. Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 21 Topics: Bone Resorption; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Neoplasms; Pamidronate; Zoledronic Acid	2002
Injectable bisphosphonates in the treatment of postmenopausal osteoporosis. Aging clinical and experimental research, 2003, Volume: 15, Issue:4 Topics: Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Female; Humans; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Middle Aged; Osteoporosis, Postmenopausal; Pamidronate; Zoledronic Acid	2003
Bisphosphonate therapy in the oncology setting. Expert opinion on emerging drugs, 2003, Volume: 8, Issue:2 Topics: Administration, Oral; Bone Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Humans; Imidazoles; Injections, Intravenous; Pamidronate; Zoledronic Acid	2003
Safety and convenience of a 15-minute infusion of zoledronic acid. The oncologist, 2004, Volume: 9, Issue:3 Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Pamidronate; Time Factors; Zoledronic Acid	2004
Bisphosphonates in the treatment of skeletal metastases. Seminars in oncology, 2004, Volume: 31, Issue:5 Suppl 10 Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Imidazoles; Pamidronate; Zoledronic Acid	2004
The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 1: Mechanisms of action, role of biomarkers and preclinical applications. Oncology, 2005, Volume: 68, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Clodronic Acid; Diphosphonates; Etidronic Acid; False Negative Reactions; Fluorodeoxyglucose F18; Humans; Ibandronic Acid; Imidazoles; Lung Neoplasms; Pamidronate; Positron-Emission Tomography; Predictive Value of Tests; Therapeutic Equivalency; Zoledronic Acid	2005
Bisphosphonates in breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:5 Topics: Administration, Oral; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Neoplasm Staging; Pamidronate; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome; Zoledronic Acid	2005
[Pharmacological treatment of osteitis deformans (Paget's bone disease)]. Ugeskrift for laeger, 2005, Feb-28, Volume: 167, Issue:9 Topics: Alendronate; Analgesics, Non-Narcotic; Antimetabolites; Calcitonin; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Osteitis Deformans; Pamidronate; Radionuclide Imaging; Risedronic Acid	2005
Evolving role of bisphosphonates in women undergoing treatment for localized and advanced breast cancer. Clinical breast cancer, 2005, Volume: 5 Suppl, Issue:2 Topics: Antineoplastic Agents; Aromatase Inhibitors; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Osteonecrosis; Pamidronate; Quality of Life; Randomized Controlled Trials as Topic; United States; Women's Health; Zoledronic Acid	2005
Should oral bisphosphonates be standard of care in women with early breast cancer? Breast cancer research and treatment, 2005, Volume: 90, Issue:3 Topics: Antimetabolites; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Female; Humans; Pamidronate; Prognosis; Survival	2005
Fracture prevention in postmenopausal women. Clinical evidence, 2006, Issue:15 Topics: Aged; Alendronate; Bone Density Conservation Agents; Calcitonin; Calcium; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Spontaneous; Hormone Replacement Therapy; Humans; Ibandronic Acid; Osteoporosis, Postmenopausal; Pamidronate; Parathyroid Hormone; Risedronic Acid; Selective Estrogen Receptor Modulators; Vitamin D	2006
Efficacy of clodronate, pamidronate, and zoledronate in reducing morbidity and mortality in cancer patients with bone metastasis: a meta-analysis of randomized clinical trials. Clinical therapeutics, 2009, Volume: 31, Issue:5 Topics: Adult; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Male; Pamidronate; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Treatment Outcome; Zoledronic Acid	2009
[Bisphosphonates in adjuvant therapy of breast cancer]. Medizinische Klinik (Munich, Germany : 1983), 2010, Volume: 105, Issue:9 Topics: Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Controlled Clinical Trials as Topic; Diphosphonates; Drug Approval; Estrogen Antagonists; Evidence-Based Medicine; Female; Humans; Imidazoles; Neoplasm Staging; Osteoporosis; Pamidronate; Survival Rate; Zoledronic Acid	2010
Bisphosphonates as anticancer therapy for early breast cancer. Clinical breast cancer, 2010, Oct-01, Volume: 10, Issue:5 Topics: Apoptosis; Bone Density Conservation Agents; Breast Neoplasms; Cell Proliferation; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Neovascularization, Physiologic; Pamidronate; Randomized Controlled Trials as Topic; Zoledronic Acid	2010
Established role of bisphosphonate therapy for prevention of skeletal complications from myeloma bone disease. Critical reviews in oncology/hematology, 2011, Volume: 77 Suppl 1 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Mice; Multiple Myeloma; Osteolysis; Pamidronate; Risk Factors; Spinal Cord Compression; Zoledronic Acid	2011
Supportive therapy in multiple myeloma. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2011, Volume: 183 Topics: Anemia; Blood Transfusion; Bone Diseases; Calcitonin; Clodronic Acid; Diphosphonates; Erythropoietin; Fractures, Bone; Hematinics; Humans; Hypercalcemia; Imidazoles; Multiple Myeloma; Osteoporosis; Pamidronate; Recombinant Proteins; Renal Insufficiency; Zoledronic Acid	2011
Bisphosphonates in multiple myeloma: a network meta-analysis. The Cochrane database of systematic reviews, 2012, May-16, Issue:5 Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Etidronic Acid; Fractures, Bone; Humans; Imidazoles; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Zoledronic Acid	2012
Bone-targeted agents: preventing skeletal complications in prostate cancer. The Urologic clinics of North America, 2012, Volume: 39, Issue:4 Topics: Androgen Antagonists; Antibodies, Monoclonal, Humanized; Bone Density; Bone Neoplasms; Clinical Trials as Topic; Clodronic Acid; Denosumab; Diphosphonates; Fractures, Spontaneous; Humans; Imidazoles; Male; Osteoclasts; Osteoporosis; Pamidronate; Prostatic Neoplasms; Quality of Life; Samarium; Toremifene; Zoledronic Acid	2012
Bisphosphonates in the adjuvant setting of breast cancer therapy--effect on survival: a systematic review and meta-analysis. PloS one, 2013, Volume: 8, Issue:8 Topics: Antineoplastic Agents; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Disease-Free Survival; Etidronic Acid; Female; Humans; Ibandronic Acid; Pamidronate; Proportional Hazards Models; Randomized Controlled Trials as Topic; Research Design; Risedronic Acid; Risk; Treatment Outcome	2013
Comparative efficacy of bisphosphonates in metastatic breast and prostate cancer and multiple myeloma: a mixed-treatment meta-analysis. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Dec-15, Volume: 19, Issue:24 Topics: Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Neoplasm Metastasis; Pamidronate; Prostatic Neoplasms; Zoledronic Acid	2013
Zoledronic acid in the management of bone disease as a consequence of multiple myeloma: a review. European journal of haematology, 2014, Volume: 92, Issue:3 Topics: Antineoplastic Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Drug Monitoring; Humans; Ibandronic Acid; Imidazoles; Multiple Myeloma; Pamidronate; Zoledronic Acid	2014
Crosstalk between bone niche and immune system: osteoimmunology signaling as a potential target for cancer treatment. Cancer treatment reviews, 2015, Volume: 41, Issue:2 Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; Bone Diseases; Bone Neoplasms; Bone Remodeling; Bone Resorption; Clodronic Acid; Denosumab; Diphosphonates; Humans; Ibandronic Acid; Imidazoles; Immune System; Osteoclasts; Osteoprotegerin; Pamidronate; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Treatment Outcome; Zoledronic Acid	2015
Experimental evidence of pharmacological management of anchorage in Orthodontics: A systematic review. Dental press journal of orthodontics, 2015, Volume: 20, Issue:5 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Bone Remodeling; Celecoxib; Clodronic Acid; Diclofenac; Diphosphonates; Humans; Imidazoles; Interferon-gamma; Isoxazoles; Lactones; Mice; Orthodontic Anchorage Procedures; Osteoclasts; Osteoprotegerin; Pamidronate; Rats; Resveratrol; Stilbenes; Sulfones; Tooth Mobility; Tooth Movement Techniques; Zoledronic Acid	2015
[Therapeutic practice of bisphosphonate use and related pharmaceutical issues I]. Acta pharmaceutica Hungarica, 2016, Volume: 86, Issue:1 Topics: Alendronate; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Bone; Humans; Hungary; Ibandronic Acid; Imidazoles; Osteoporosis; Pamidronate; Risedronic Acid; Zoledronic Acid	2016
Bisphosphonates in multiple myeloma: an updated network meta-analysis. The Cochrane database of systematic reviews, 2017, 12-18, Volume: 12 Topics: Antineoplastic Agents; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Disease-Free Survival; Etidronic Acid; Fractures, Bone; Humans; Imidazoles; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Spinal Fractures; Zoledronic Acid	2017
Bisphosphonates or RANK-ligand-inhibitors for men with prostate cancer and bone metastases: a network meta-analysis. The Cochrane database of systematic reviews, 2020, 12-03, Volume: 12 Topics: Adult; Alendronate; Antineoplastic Agents, Hormonal; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Denosumab; Diphosphonates; Etidronic Acid; Humans; Male; Network Meta-Analysis; Pamidronate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Randomized Controlled Trials as Topic; RANK Ligand; Risedronic Acid; Zoledronic Acid	2020
Treatment for osteoporosis in people with beta-thalassaemia. The Cochrane database of systematic reviews, 2023, 05-09, Volume: 5 Topics: Adult; Alendronate; beta-Thalassemia; Child; Clodronic Acid; Denosumab; Diphosphonates; Female; Fractures, Bone; Humans; Male; Middle Aged; Osteoporosis; Pamidronate	2023

Trials

15 trial(s) available for pamidronate and clodronic acid

Article	Year
Hypercalcemia and bone metastases in breast cancer. Current opinion in oncology, 1990, Volume: 2, Issue:6 Topics: Alendronate; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Hypercalcemia; Neoplasm Proteins; Pamidronate; Parathyroid Hormone-Related Protein; Proteins; Transforming Growth Factors	1990
Comparison of three intravenous bisphosphonates in cancer-associated hypercalcaemia. Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673 Topics: Administration, Oral; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Drug Administration Schedule; Drug Evaluation; Etidronic Acid; Humans; Infusions, Intravenous; Middle Aged; Neoplasms; Pamidronate; Randomized Controlled Trials as Topic; Recurrence; Time Factors	1989
Efficacious management with aminobisphosphonate (APD) in Paget's disease of bone. Clinical orthopaedics and related research, 1987, Issue:217 Topics: Administration, Oral; Alkaline Phosphatase; Biopsy; Bone and Bones; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; Hydroxyproline; Infusions, Intravenous; Male; Osteitis Deformans; Pamidronate; Remission Induction; Time Factors	1987
A randomised double-blind comparison of intravenous pamidronate and clodronate in the hypercalcaemia of malignancy. British journal of cancer, 1995, Volume: 72, Issue:5 Topics: Bone Neoplasms; Bone Resorption; Clodronic Acid; Diphosphonates; Double-Blind Method; Humans; Hypercalcemia; Pamidronate; Treatment Outcome	1995
Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy. Bone, 1996, Volume: 18, Issue:2 Topics: Aged; Aged, 80 and over; Bone Resorption; Clodronic Acid; Diphosphonates; Female; Follow-Up Studies; Humans; Ibandronic Acid; Interleukin-1; Interleukin-6; Male; Middle Aged; Neoplasms; Pamidronate; Tumor Necrosis Factor-alpha	1996
Evaluation of new bone resorption markers in a randomized comparison of pamidronate or clodronate for hypercalcemia of malignancy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers; Bone Neoplasms; Bone Resorption; Calcium; Clodronic Acid; Collagen; Collagen Type I; Diphosphonates; Double-Blind Method; Female; Humans; Hydroxyproline; Hypercalcemia; Male; Middle Aged; Pamidronate; Parathyroid Hormone; Peptides	1997
An in vitro and in vivo study of cytokines in the acute-phase response associated with bisphosphonates. Calcified tissue international, 1997, Volume: 61, Issue:5 Topics: Acute-Phase Reaction; Adult; Bone Diseases; Carrier Proteins; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Injections, Intravenous; Interleukin-1; Interleukin-6; Leukocyte Count; Male; Middle Aged; Pamidronate; Tumor Necrosis Factor-alpha; Zoledronic Acid	1997
Bisphosphonates in multiple myeloma. Cancer, 1997, Oct-15, Volume: 80, Issue:8 Suppl Topics: Bone Diseases; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Multiple Myeloma; Pain; Pamidronate; Randomized Controlled Trials as Topic	1997
[Bisphosphonates in the adjuvant therapy of breast cancer-- pathophysiology, animal models, and clinical experiences]. Gynakologisch-geburtshilfliche Rundschau, 1998, Volume: 38, Issue:2 Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Pamidronate; Rats	1998
Effect of first treatment with aminobisphosphonates pamidronate and ibandronate on circulating lymphocyte subpopulations. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Clodronic Acid; Diphosphonates; Female; Humans; Ibandronic Acid; Lectins, C-Type; Lymphocyte Subsets; Male; Middle Aged; Pamidronate; Prospective Studies; Tumor Necrosis Factor-alpha	2000
[Analgesic effect of a diphosphonate perfusion during the acute phase of vertebral compression in the elderly subject]. La Revue de medecine interne, 2000, Volume: 21, Issue:11 Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Female; Humans; Male; Pamidronate; Perfusion; Spinal Cord Compression	2000
Comparison of the effects of intravenous pamidronate and oral clodronate on symptoms and bone resorption in patients with metastatic bone disease. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:10 Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Bone Neoplasms; Bone Resorption; Clodronic Acid; Collagen; Diphosphonates; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pain; Pamidronate	2001
Bisphosphonate resistance in Paget's disease of bone. Arthritis and rheumatism, 2003, Volume: 48, Issue:8 Topics: Aged; Aged, 80 and over; Alendronate; Alkaline Phosphatase; Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Drug Resistance; Humans; Injections, Intravenous; Middle Aged; Osteitis Deformans; Pamidronate	2003
Clodronate as a single-dose intravenous infusion effectively provides short-term correction of malignant hypercalcemia. Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:7 Topics: Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Female; Humans; Hypercalcemia; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Pamidronate	2003
Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-20, Volume: 24, Issue:30 Topics: Adult; Aged; Aged, 80 and over; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Disease Progression; Drug Resistance; Female; Humans; Imidazoles; Middle Aged; Pain; Palliative Care; Pamidronate; Prospective Studies; Treatment Outcome; Zoledronic Acid	2006

Other Studies

93 other study(ies) available for pamidronate and clodronic acid

Article	Year
Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. Proceedings of the National Academy of Sciences of the United States of America, 2007, Jul-24, Volume: 104, Issue:30 Topics: Crystallography, X-Ray; Diphosphonates; DNA Nucleotidyltransferases; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Microbial Viability; Models, Molecular; Protein Structure, Tertiary	2007
Structural requirements for bisphosphonate binding on hydroxyapatite: NMR study of bisphosphonate partial esters. ACS medicinal chemistry letters, 2015, Apr-09, Volume: 6, Issue:4 Topics:	2015
Progression delay of prostate tumor skeletal metastasis effects by bisphosphonates. The Journal of urology, 1992, Volume: 148, Issue:4 Topics: Animals; Bone Neoplasms; Clodronic Acid; Diphosphonates; Male; Pamidronate; Prostatic Neoplasms; Rats; Time Factors; Tumor Cells, Cultured	1992
Effects of clodronate and pamidronate on splenic and hepatic phagocytic cells of mice. Pharmacology & toxicology, 1991, Volume: 68, Issue:4 Topics: Animals; Clodronic Acid; Diphosphonates; Drug Carriers; Liposomes; Liver; Male; Mice; Pamidronate; Phagocytes; Spleen	1991
Bisphosphonate treatment of bone metastases and hypercalcemia of malignancy. Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:8 Topics: Animals; Bone and Bones; Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Neoplasms; Pamidronate	1991
BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:9 Topics: Alendronate; Animals; Benzoates; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Etidronic Acid; Ibandronic Acid; Injections, Intravenous; Osteoclasts; Pamidronate; Rats; Retinoids; Risedronic Acid; Spectrophotometry, Atomic; Tetracycline; Thyroxine	1991
Modulation of PTH-stimulated osteoclastic resorption by bisphosphonates in fetal mouse bone explants. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:11 Topics: Animals; Bone Resorption; Calcium; Clodronic Acid; Culture Techniques; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mice, Inbred Strains; Pamidronate; Parathyroid Hormone; Pregnancy	1991
Inhibition of bone resorption by bisphosphonates: interactions between bisphosphonates, osteoclasts, and bone. Calcified tissue international, 1991, Volume: 49, Issue:6 Topics: Animals; Bone and Bones; Bone Marrow Cells; Bone Resorption; Calcitonin; Cells, Cultured; Clodronic Acid; Culture Techniques; Diphosphonates; Mice; Microscopy, Electron; Osteoclasts; Pamidronate; Rats; Rats, Inbred Strains	1991
Use of bisphosphonates in hypercalcaemia due to malignancy. Lancet (London, England), 1990, Mar-24, Volume: 335, Issue:8691 Topics: Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Neoplasms; Pamidronate	1990
Comparison of the distribution of three bisphosphonates in mice. Pharmacology & toxicology, 1990, Volume: 66, Issue:4 Topics: Animals; Clodronic Acid; Diphosphonates; Etidronic Acid; Injections, Intravenous; Male; Mice; Pamidronate; Tissue Distribution	1990
Diphosphonates inhibit human osteoblast secretion and proliferation. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:2 Topics: Alkaline Phosphatase; Calcitriol; Cell Division; Cells, Cultured; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Kinetics; Osteoblasts; Pamidronate; Thymidine	1989
Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow. The Journal of clinical investigation, 1989, Volume: 83, Issue:6 Topics: Bone Marrow; Cell Count; Cell Survival; Cells, Cultured; Clodronic Acid; Diphosphonates; Growth Inhibitors; Humans; Osteoclasts; Osteogenesis; Pamidronate; Stem Cells	1989
Bisphosphonates can reduce osteoclastic bone resorption by two different mechanisms. Advances in experimental medicine and biology, 1986, Volume: 208 Topics: Animals; Bone and Bones; Bone Resorption; Cell Differentiation; Chemotaxis; Clodronic Acid; Culture Techniques; Diphosphonates; Etidronic Acid; Female; Liver; Metacarpus; Mice; Osteoclasts; Pamidronate; Pregnancy; Radius	1986
Effects of four bisphosphonates on bone resorption, lysosomal enzyme release, protein synthesis and mitotic activities in mouse calvarial bones in vitro. Bone, 1987, Volume: 8, Issue:3 Topics: Animals; Bone and Bones; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; In Vitro Techniques; Kinetics; Lysosomes; Mice; Minerals; Mitosis; Pamidronate; Parathyroid Hormone; Protein Biosynthesis	1987
Ultrastructural effects of diphosphonates on dental enamel. Advances in dental research, 1987, Volume: 1, Issue:2 Topics: Clodronic Acid; Dental Enamel; Diphosphonates; Etidronic Acid; Humans; Pamidronate; Surface Properties	1987
Bisphosphonates and bone resorption: effects on collagenase and lysosomal enzyme excretion. Life sciences, 1985, Dec-16, Volume: 37, Issue:24 Topics: Acetylglucosaminidase; Animals; Bone Resorption; Calcium; Clodronic Acid; Depression, Chemical; Diphosphonates; Glucuronidase; Heparin; Lysosomes; Mice; Microbial Collagenase; Organ Culture Techniques; Osteoblasts; Osteoclasts; Pamidronate; Parathyroid Hormone	1985
New inhibitors of osteolysis: implications for hypercalcemia and bone metastases. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8 Topics: Amifostine; Bone Neoplasms; Bone Resorption; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Osteolysis; Pamidronate; Plicamycin	1986
Diphosphonates for otospongiosis. The American journal of otology, 1985, Volume: 6, Issue:1 Topics: Adult; Bone Development; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Male; Mandible; Mandibular Diseases; Middle Aged; Osteitis Deformans; Otosclerosis; Pamidronate	1985
In vitro effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on the function of mononuclear phagocytes in lymphocyte proliferation. Immunology, 1982, Volume: 47, Issue:1 Topics: Cell Division; Cells, Cultured; Clodronic Acid; Diphosphonates; DNA; Dose-Response Relationship, Drug; Etidronic Acid; Humans; Lymphocyte Activation; Lymphocytes; Pamidronate; Phagocytes; Pokeweed Mitogens	1982
Inhibition by diphosphonates of bone resorption induced by the Walker tumor of the rat. Cancer research, 1984, Volume: 44, Issue:7 Topics: Animals; Bone and Bones; Bone Resorption; Carcinoma 256, Walker; Clodronic Acid; Diphosphonates; Etidronic Acid; Male; Osteoclasts; Pamidronate; Rats; Rats, Inbred Strains	1984
[Diphosphonates in the treatment of hypercalcemia]. La Revue de medecine interne, 1984, Volume: 5, Issue:4 Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Hypercalcemia; Hyperparathyroidism; Pamidronate	1984
Dichloromethylene diphosphonate and calcium and phosphate metabolism. The New England journal of medicine, 1980, Jul-17, Volume: 303, Issue:3 Topics: Animals; Calcium; Clodronic Acid; Diphosphonates; Pamidronate; Phosphates; Propanolamines; Rats; Urine	1980
APD in Paget's disease of bone. Role of the mononuclear phagocyte system? Arthritis and rheumatism, 1980, Volume: 23, Issue:10 Topics: Animals; Arthritis, Rheumatoid; Calcitonin; Clodronic Acid; Diphosphonates; Drug Therapy, Combination; Etidronic Acid; Humans; Hydroxyproline; Lymphocyte Activation; Osteitis Deformans; Pamidronate; Phagocytes; Rats; Zinc	1980
The effects of bisphosphonates on the resorption cycle of isolated osteoclasts. Calcified tissue international, 1994, Volume: 55, Issue:5 Topics: Actins; Animals; Binding Sites; Bone Resorption; Cell Count; Cells, Cultured; Clodronic Acid; Diphosphonates; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Lectins; Microscopy, Electron, Scanning; Osteoclasts; Pamidronate; Rats; Staining and Labeling; Vinculin; Wheat Germ Agglutinins	1994
Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro. Journal of drug targeting, 1994, Volume: 2, Issue:4 Topics: Animals; Calcium; Cell Division; Cell Line; Chlorocebus aethiops; Clodronic Acid; Delayed-Action Preparations; Diphosphonates; Drug Carriers; Etidronic Acid; Humans; Kidney; Leukemia; Liposomes; Macrophages; Mice; Pamidronate; Phagocytes; Tumor Cells, Cultured	1994
Human neutrophil priming: chemiluminescence modified by hydroxyapatite and three bisphosphonates in vitro. Journal of clinical & laboratory immunology, 1993, Volume: 40, Issue:2 Topics: Adult; Clodronic Acid; Diphosphonates; Durapatite; Etidronic Acid; Humans; Luminescent Measurements; Neutrophil Activation; Neutrophils; Pamidronate; Peroxidase	1993
Bisphosphonates act on rat bone resorption through the mediation of osteoblasts. The Journal of clinical investigation, 1993, Volume: 91, Issue:5 Topics: Alendronate; Animals; Animals, Newborn; Bone Resorption; Cell Line; Cells, Cultured; Clodronic Acid; Culture Media, Conditioned; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Ibandronic Acid; Kinetics; Osteoblasts; Pamidronate; Parathyroid Hormone; Rats; Rats, Wistar; Time Factors	1993
Therapeutic strategy in Paget's disease of bone. Bone, 1995, Volume: 17, Issue:5 Suppl Topics: Administration, Oral; Adult; Aged; Alkaline Phosphatase; Analgesics, Non-Narcotic; Biomarkers; Bone and Bones; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Follow-Up Studies; Humans; Hydroxyproline; Injections, Intravenous; Longitudinal Studies; Male; Middle Aged; Osteitis Deformans; Pamidronate; Radiography; Risk Assessment; Skull	1995
Different effects of three bisphosphonates on nitric oxide production by RAW 264 macrophage-like cells in vitro. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2 Topics: Alendronate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Clodronic Acid; Diphosphonates; Female; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide; Pamidronate	1996
Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits. The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:2 Topics: Analysis of Variance; Animals; Aorta; Aortic Valve; Arteriosclerosis; Carbon Radioisotopes; Clodronic Acid; Diphosphonates; Etidronic Acid; Male; Mitral Valve; Muscle, Smooth, Vascular; Pamidronate; Rabbits; Reference Values; Time Factors; Tissue Distribution	1996
Role of bisphosphonates in prevention and treatment of bone metastases from breast cancer. The Canadian journal of oncology, 1995, Volume: 5 Suppl 1 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Hypercalcemia; Multiple Myeloma; Osteoporosis; Pain; Pamidronate	1995
Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages. Molecular pharmacology, 1996, Volume: 50, Issue:5 Topics: Acid Phosphatase; Analgesics, Non-Narcotic; Animals; Apoptosis; Bisbenzimidazole; Cells, Cultured; Clodronic Acid; Diphosphonates; Fluorescent Dyes; Isoenzymes; Liposomes; Macrophages, Peritoneal; Mice; Osteoclasts; Pamidronate; Rats; Staining and Labeling; Tartrate-Resistant Acid Phosphatase	1996
Bisphosphonates spearhead new approach to treating bone metastases. Journal of the National Cancer Institute, 1997, Jan-15, Volume: 89, Issue:2 Topics: Animals; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Growth Substances; Humans; Pamidronate; Quality of Life	1997
Inhibition of calcium oxalate urolithiasis in a rat model of lithogenesis using bisphosphonates. Journal of endourology, 1997, Volume: 11, Issue:1 Topics: Analgesics, Non-Narcotic; Animals; Calcium; Calcium Oxalate; Clodronic Acid; Creatinine; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Injections, Intraperitoneal; Male; Pamidronate; Rats; Rats, Sprague-Dawley; Urinary Bladder Calculi; Zinc	1997
Effects of bisphosphonates on alkaline phosphatase activity, mineralization, and prostaglandin E2 synthesis in the clonal osteoblast-like cell line MC3T3-E1. Prostaglandins, leukotrienes, and essential fatty acids, 1997, Volume: 56, Issue:2 Topics: Alendronate; Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Cell Line; Clodronic Acid; Culture Media; Dinoprostone; Diphosphonates; DNA; Glycerophosphates; Mice; Osteoblasts; Pamidronate	1997
Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium. Arthritis and rheumatism, 1997, Volume: 40, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cartilage, Articular; Clodronic Acid; Collagenases; Diphosphonates; Female; Humans; Immunoblotting; Immunohistochemistry; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Middle Aged; Osteoarthritis; Pamidronate; Penicillamine; Recombinant Proteins; RNA, Messenger; Synovial Membrane	1997
Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices. Cancer research, 1997, Sep-15, Volume: 57, Issue:18 Topics: Bone Matrix; Bone Neoplasms; Breast Neoplasms; Calcification, Physiologic; Cell Adhesion; Cell Adhesion Molecules; Clodronic Acid; Diphosphonates; Extracellular Matrix; Female; Humans; Ibandronic Acid; In Vitro Techniques; Integrins; Male; Neoplasm Metastasis; Osteoblasts; Pamidronate; Prostatic Neoplasms; Pyridines; Pyridinium Compounds; Tumor Cells, Cultured	1997
Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity. British journal of haematology, 1997, Volume: 98, Issue:3 Topics: Apoptosis; Clodronic Acid; Diphosphonates; DNA, Neoplasm; Humans; Multiple Myeloma; Pamidronate; Tumor Cells, Cultured	1997
Transformation of bisphosphonates into insoluble material in human blood in vitro. Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:4 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Biotransformation; Carbon Radioisotopes; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Humans; In Vitro Techniques; Male; Pamidronate	1998
Accumulation of bisphosphonates in human artery and their effects on human and rat arterial function in vitro. Pharmacology & toxicology, 1998, Volume: 83, Issue:3 Topics: Animals; Arteries; Calcium Channel Blockers; Clodronic Acid; Diphosphonates; Drug Synergism; Etidronic Acid; Humans; Hypercalcemia; In Vitro Techniques; Male; Nifedipine; Osteoporosis; Pamidronate; Rats; Rats, Wistar; Vasoconstriction	1998
Skin reactions associated with bisphosphonates: a report of 3 cases and an approach to management. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:4 Pt 1 Topics: Adult; Alendronate; Antineoplastic Agents; Breast Neoplasms; Clodronic Acid; Diphosphonates; Drug Hypersensitivity; Etidronic Acid; Female; Humans; Middle Aged; Pamidronate; Skin Tests; Urticaria	1998
Pharmacokinetics of bisphosphonates in rabbits. Pharmacology & toxicology, 1999, Volume: 84, Issue:1 Topics: Animals; Clodronic Acid; Diphosphonates; Etidronic Acid; Male; Pamidronate; Rabbits; Tissue Distribution	1999
Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo. Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2 Topics: Animals; Bone Resorption; Brain; Carbon-Carbon Double Bond Isomerases; Cattle; Clodronic Acid; Dimethylallyltranstransferase; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hemiterpenes; Ibandronic Acid; Mice; Multienzyme Complexes; Nitrogen; Pamidronate	1999
Bisphosphonates induce apoptosis in human breast cancer cell lines. British journal of cancer, 2000, Volume: 82, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Division; Cell Nucleus; Cell Survival; Clodronic Acid; Diphosphonates; DNA Fragmentation; Female; Humans; Imidazoles; Kinetics; Pamidronate; Pyrrolidines; Tumor Cells, Cultured; Zoledronic Acid	2000
[Biosphonates in oncology]. Presse medicale (Paris, France : 1983), 2000, Apr-08, Volume: 29, Issue:13 Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Bone; Humans; Neoplasms; Osteolysis; Pain; Pamidronate; Spinal Cord Compression	2000
Osteoporosis pseudoglioma syndrome: treatment of spinal osteoporosis with intravenous bisphosphonates. The Journal of pediatrics, 2000, Volume: 137, Issue:3 Topics: Analgesics, Non-Narcotic; Bone Density; Child; Clodronic Acid; Diphosphonates; Female; Fractures, Bone; Growth; Humans; Infusions, Intravenous; Male; Osteoporosis; Pain; Pamidronate; Spine; Syndrome; Vision Disorders	2000
Bisphosphonates induce breast cancer cell death in vitro. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:11 Topics: Amino Acid Chloromethyl Ketones; Annexins; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase Inhibitors; Caspases; Cell Death; Cell Nucleus; Clodronic Acid; Cysteine Proteinase Inhibitors; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans; Ibandronic Acid; Imidazoles; Kinetics; Pamidronate; Tumor Cells, Cultured; Zoledronic Acid	2000
Analgesic effect of bisphosphonates in mice. Pain, 2001, Volume: 91, Issue:3 Topics: Abdomen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Gastrointestinal Motility; Male; Mice; Mice, Inbred Strains; Pain; Pain Measurement; Pamidronate; Tail	2001
Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line. British journal of cancer, 2001, Apr-06, Volume: 84, Issue:7 Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Carrier Proteins; Cell Division; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glycoproteins; Growth Inhibitors; Membrane Glycoproteins; Osteoprotegerin; Osteosarcoma; Pamidronate; RANK Ligand; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Tumor Cells, Cultured	2001
Use of bisphosphonates for the treatment of metastatic bone pain. A survey of palliative physicians in the UK. Palliative medicine, 2001, Volume: 15, Issue:2 Topics: Bone Neoplasms; Clodronic Acid; Diphosphonates; Drug Costs; Humans; Pain; Palliative Care; Pamidronate; Practice Patterns, Physicians'; Surveys and Questionnaires; United Kingdom	2001
The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro. Anti-cancer drugs, 2001, Volume: 12, Issue:5 Topics: Antineoplastic Agents; Bone Neoplasms; Cell Division; Clodronic Acid; Diphosphonates; DNA Fragmentation; DNA, Neoplasm; Humans; Osteosarcoma; Pamidronate; Phosphatidylserines; Tumor Cells, Cultured	2001
Bisphosphonates may be useful in treatment of bone metastases. Journal of the National Cancer Institute, 2001, Jul-18, Volume: 93, Issue:14 Topics: Analgesics, Non-Narcotic; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Clodronic Acid; Diphosphonates; Female; Humans; Male; Pamidronate; Prostatic Neoplasms; Quality of Life; Survival Analysis; Treatment Outcome	2001
[Is pamidronate or clodronate better?]. Vnitrni lekarstvi, 2002, Volume: 48, Issue:4 Topics: Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clodronic Acid; Diphosphonates; Female; Humans; Pamidronate	2002
Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts. Journal of endocrinological investigation, 2002, Volume: 25, Issue:6 Topics: Adult; Aged; Alkaline Phosphatase; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Clodronic Acid; Collagen Type I; Culture Media; Culture Media, Serum-Free; Diphosphonates; Fetal Blood; Humans; Ibandronic Acid; Imidazoles; Middle Aged; Osteoblasts; Pamidronate; Zoledronic Acid	2002
American Society of Clinical Oncology clinical practice guidelines: the role of bisphosphonates in multiple myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-01, Volume: 20, Issue:17 Topics: Clodronic Acid; Diphosphonates; Drug Monitoring; Humans; Imidazoles; Multiple Myeloma; Osteolysis; Pamidronate; Zoledronic Acid	2002
Clodronate inhibits adrenocortical cell proliferation and P450c21 activity. The Journal of endocrinology, 2002, Volume: 174, Issue:3 Topics: Adrenal Cortex; Animals; Antimetabolites; Cattle; Cell Division; Clodronic Acid; Depression, Chemical; Diphosphonates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Pamidronate; Steroid 21-Hydroxylase; Tumor Cells, Cultured	2002
Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain. Pain, 2002, Volume: 100, Issue:3 Topics: Animals; Bone Density; Bone Neoplasms; Clodronic Acid; Diphosphonates; Female; Hyperalgesia; Hyperesthesia; Imidazoles; Models, Animal; Neoplasm Transplantation; Observer Variation; Pain; Pain Measurement; Pain Threshold; Pamidronate; Radiography; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tibia; Touch; Treatment Outcome; Zoledronic Acid	2002
Bisphosphonates for RSDS and prostate cancer--more benefit then revealed! Joint bone spine, 2002, Volume: 69, Issue:5 Topics: Analgesics, Non-Narcotic; Clodronic Acid; Controlled Clinical Trials as Topic; Diphosphonates; Double-Blind Method; Humans; Male; Pamidronate; Prostatic Neoplasms; Reflex Sympathetic Dystrophy; Treatment Outcome	2002
Bisphosphonates in prostate cancer: where are we and where should we go? Journal of the National Cancer Institute, 2003, Sep-03, Volume: 95, Issue:17 Topics: Administration, Oral; Androgen Antagonists; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Neoplasms; Clodronic Acid; Diphosphonates; Fractures, Spontaneous; Humans; Imidazoles; Infusions, Intravenous; Male; Neoplasms, Hormone-Dependent; Osteoporosis; Pamidronate; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Zoledronic Acid	2003
Regulation of MMP-9 (gelatinase B) in activated human monocyte/macrophages by two different types of bisphosphonates. Life sciences, 2003, Sep-26, Volume: 73, Issue:19 Topics: Clodronic Acid; Culture Media, Conditioned; Diphosphonates; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Macrophages; Matrix Metalloproteinase 9; Monocytes; Pamidronate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2003
The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro. Anti-cancer drugs, 2003, Volume: 14, Issue:9 Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Humans; Lovastatin; Pamidronate; Sarcoma, Ewing	2003
Long-term analgesic effect of clodronate in rodents. Bone, 2003, Volume: 33, Issue:4 Topics: Analgesics, Non-Narcotic; Animals; Aspirin; Behavior, Animal; Clodronic Acid; Diphosphonates; Female; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Morphine; Pamidronate; Sex Characteristics; Time Factors	2003
Utilization of palliative radiotherapy for breast cancer patients with bone metastases treated with bisphosphonates-Toronto Sunnybrook Regional Cancer Centre experience. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Extremities; Female; Humans; Middle Aged; Ontario; Palliative Care; Pamidronate; Radiotherapy, Adjuvant; Retrospective Studies; Spine; Treatment Outcome	2004
A single bisphosphonate infusion is associated with improved functional capacity in elderly subjects with primary hyperparathyroidism. Aging clinical and experimental research, 2003, Volume: 15, Issue:6 Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antimetabolites; Bone and Bones; Bone Resorption; Calcium; Clodronic Acid; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Male; Pamidronate; Retrospective Studies; Treatment Outcome	2003
Risedronate and pamidronate treatment in the clinical management of patients with severe Paget's disease of bone and acquired resistance to bisphosphonates. Calcified tissue international, 2004, Volume: 75, Issue:3 Topics: Administration, Oral; Alkaline Phosphatase; Calcitriol; Clodronic Acid; Diphosphonates; Drug Tolerance; Etidronic Acid; Female; Humans; Injections, Intravenous; Male; Middle Aged; Osteitis Deformans; Pain; Pamidronate; Parathyroid Hormone; Risedronic Acid; Treatment Outcome	2004
Cost analysis of secondary prophylaxis with oral clodronate versus pamidronate in metastatic breast cancer patients. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:12 Topics: Antimetabolites; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Chi-Square Distribution; Clodronic Acid; Cost-Benefit Analysis; Diphosphonates; Female; Humans; Middle Aged; Pamidronate; Statistics, Nonparametric	2004
Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells. British journal of cancer, 2004, Aug-16, Volume: 91, Issue:4 Topics: Antimetabolites; Antineoplastic Agents; Cell Cycle; Clodronic Acid; Diphosphonates; Disease Progression; Humans; Imidazoles; Melanoma; Nitrogen; Pamidronate; Skin Neoplasms; Tumor Cells, Cultured; Zoledronic Acid	2004
In vitro toxicity of bisphosphonates on human neuroblastoma cell lines. Anti-cancer drugs, 2004, Volume: 15, Issue:8 Topics: Alendronate; Apoptosis; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Diphosphonates; Drug Screening Assays, Antitumor; Germany; Humans; Ibandronic Acid; Imidazoles; Neuroblastoma; Pamidronate; Time Factors; Zoledronic Acid	2004
Bacterial adhesion to bisphosphonate coated hydroxyapatite. Journal of materials science. Materials in medicine, 2005, Volume: 16, Issue:4 Topics: Bacterial Adhesion; Clodronic Acid; Coated Materials, Biocompatible; Diphosphonates; Durapatite; Equipment Contamination; Molecular Structure; Pamidronate; Staphylococcus aureus	2005
The issue of renal safety of zoledronic acid from a nephrologist's point of view. The oncologist, 2005, Volume: 10, Issue:5 Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Pamidronate; Time Factors; Zoledronic Acid	2005
"Safety and convenience of a 15-minute infusion of zoledronic acid": not so safe. The oncologist, 2005, Volume: 10, Issue:5 Topics: Antineoplastic Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Humans; Hypercalcemia; Ibandronic Acid; Imidazoles; Infusions, Intravenous; Pamidronate; Time Factors; Zoledronic Acid	2005
Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells. Molecular and cellular endocrinology, 2005, Aug-30, Volume: 240, Issue:1-2 Topics: Alendronate; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Clodronic Acid; Diphosphonates; DNA-Binding Proteins; Female; Gene Expression; Humans; Pamidronate; Telomerase; Tumor Cells, Cultured	2005
Differential effects of bisphosphonates on breast cancer cell lines. Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2 Topics: Alendronate; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Cyclin D1; Diphosphonates; DNA Fragmentation; Etidronic Acid; Female; Flow Cytometry; Humans; Ibandronic Acid; Imidazoles; Pamidronate; Risedronic Acid; RNA, Messenger; Zoledronic Acid	2007
Bisphosphonate pretreatment attenuates hungry bone syndrome postoperatively in subjects with primary hyperparathyroidism. Journal of bone and mineral metabolism, 2006, Volume: 24, Issue:3 Topics: Adult; Aged; Calcium; Clodronic Acid; Diphosphonates; Female; Humans; Hyperparathyroidism, Primary; Hypocalcemia; Male; Middle Aged; Pamidronate; Parathyroidectomy; Preoperative Care; Retrospective Studies; Syndrome	2006
Antioxidant effect of bisphosphonates and simvastatin on chondrocyte lipid peroxidation. Biochemical and biophysical research communications, 2006, Sep-22, Volume: 348, Issue:2 Topics: Animals; Antioxidants; Boron Compounds; Cattle; Cells, Cultured; Chondrocytes; Clodronic Acid; Diphosphonates; Edetic Acid; Etidronic Acid; Ferrous Compounds; Flow Cytometry; Hydrogen Peroxide; Lipid Peroxidation; Pamidronate; Risedronic Acid; Simvastatin; tert-Butylhydroperoxide	2006
Amino-bisphosphonates decrease hTERT gene expression in breast cancer in vitro. Aging clinical and experimental research, 2007, Volume: 19, Issue:2 Topics: Alendronate; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Clodronic Acid; Diphosphonates; Female; Gene Expression Regulation, Neoplastic; Humans; Pamidronate; Telomerase	2007
Development and application of a high-performance liquid chromatography-mass spectrometry method to determine alendronate in human urine. Journal of chromatography. A, 2007, Aug-10, Volume: 1160, Issue:1-2 Topics: Alendronate; Biological Availability; Chromatography, High Pressure Liquid; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Mass Spectrometry; Pamidronate; Reference Standards	2007
Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: implications for renal safety. Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:4 Topics: Animals; Bone Density Conservation Agents; Cell Line; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Geranyltranstransferase; Humans; Ibandronic Acid; Imidazoles; Inhibitory Concentration 50; Kidney; Male; Pamidronate; Rats; Rats, Sprague-Dawley; RNA, Messenger; Zoledronic Acid	2008
Treating low- and medium-potency bisphosphonate-related osteonecrosis of the jaws with a protocol for the treatment of chronic suppurative osteomyelitis: report of 7 cases. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2009, Volume: 107, Issue:2 Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Bone Density Conservation Agents; Chronic Disease; Clinical Protocols; Clodronic Acid; Debridement; Dental Implants; Diphosphonates; Female; Humans; Injections, Intravenous; Jaw Diseases; Middle Aged; Osteomyelitis; Osteonecrosis; Pamidronate; Retrospective Studies; Tooth Extraction	2009
Adjuvant bisphosphonates in breast cancer: are we witnessing the emergence of a new therapeutic strategy? European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:11 Topics: Bone Neoplasms; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Diphosphonates; Female; Humans; Imidazoles; Pamidronate; Randomized Controlled Trials as Topic; Zoledronic Acid	2009
Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro. Clinical oral investigations, 2011, Volume: 15, Issue:1 Topics: Analysis of Variance; Apoptosis; Bone Density Conservation Agents; Cell Movement; Cells, Cultured; Clodronic Acid; Diphosphonates; Endothelial Cells; Endothelium, Vascular; Humans; Ibandronic Acid; Imidazoles; Leukocytes, Mononuclear; Neovascularization, Physiologic; Pamidronate; Statistics, Nonparametric; Stem Cells; Umbilical Veins; Zoledronic Acid	2011
Bisphosphonates affect migration ability and cell viability of HUVEC, fibroblasts and osteoblasts in vitro. Oral diseases, 2011, Volume: 17, Issue:2 Topics: Apoptosis; Bone Density Conservation Agents; Cell Culture Techniques; Cell Movement; Cell Survival; Cells, Cultured; Clodronic Acid; Diphosphonates; Endothelial Cells; Endothelium, Vascular; Fibroblasts; Fluoresceins; Fluorescent Dyes; Humans; Ibandronic Acid; Imidazoles; In Situ Nick-End Labeling; Nitrogen; Osteoblasts; Pamidronate; Umbilical Veins; Zoledronic Acid	2011
Zoledronic acid in myeloma: MRC Myeloma IX. Lancet (London, England), 2010, Dec-11, Volume: 376, Issue:9757 Topics: Administration, Oral; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Diphosphonates; Drug Administration Schedule; Humans; Imidazoles; Infusions, Intravenous; Multiple Myeloma; Pamidronate; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Zoledronic Acid	2010
The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study. Clinical oral investigations, 2012, Volume: 16, Issue:1 Topics: Apoptosis; Bone Density Conservation Agents; Cell Culture Techniques; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Clodronic Acid; Coloring Agents; Diphosphonates; Fluoresceins; Fluorescent Dyes; Humans; Ibandronic Acid; Imidazoles; In Situ Nick-End Labeling; Keratinocytes; Mouth Mucosa; Pamidronate; Tetrazolium Salts; Thiazoles; Zoledronic Acid	2012
Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1. Journal of immunology (Baltimore, Md. : 1950), 2012, Apr-01, Volume: 188, Issue:7 Topics: Alendronate; Animals; Chemotaxis; Clodronic Acid; Diphosphonates; Imidazoles; Interleukin-1alpha; Interleukin-1beta; Leukocytes; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Myeloid Differentiation Factor 88; Neutrophils; Pamidronate; Peritonitis; Receptors, Interleukin-1; Zoledronic Acid	2012
International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-20, Volume: 31, Issue:18 Topics: Administration, Intravenous; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Combined Modality Therapy; Diphosphonates; Drug Therapy, Combination; Fractures, Bone; Humans; Imidazoles; International Cooperation; Magnetic Resonance Imaging; Medical Oncology; Multiple Myeloma; Osteonecrosis; Outcome Assessment, Health Care; Pamidronate; Positron-Emission Tomography; Practice Guidelines as Topic; Radiotherapy; Tomography, X-Ray Computed; Zoledronic Acid	2013
Effect of bisphosphonates on the rapidly growing male murine skeleton. Endocrinology, 2014, Volume: 155, Issue:4 Topics: Alendronate; Animals; Apoptosis; Biomechanical Phenomena; Bone and Bones; Bone Development; Bone Resorption; Chondrocytes; Clodronic Acid; Diphosphonates; Hypertrophy; Imidazoles; Male; Mice; Mice, Inbred C57BL; Pamidronate; Phenotype; X-Ray Microtomography; Zoledronic Acid	2014
In vitro effects of bisphosphonates on chemotaxis, phagocytosis, and oxidative burst of neutrophil granulocytes. Clinical oral investigations, 2015, Volume: 19, Issue:1 Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Chemotaxis; Clodronic Acid; Diphosphonates; Flow Cytometry; Granulocytes; Humans; Ibandronic Acid; Imidazoles; In Vitro Techniques; Neutrophils; Pamidronate; Phagocytosis; Respiratory Burst; Zoledronic Acid	2015
Clodronate exerts an anabolic effect on articular chondrocytes mediated through the purinergic receptor pathway. Osteoarthritis and cartilage, 2014, Volume: 22, Issue:9 Topics: Anabolic Agents; Animals; Bone Density Conservation Agents; Calcium Signaling; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Clodronic Acid; Diphosphonates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Extracellular Matrix; Matrix Metalloproteinase 13; Pamidronate; Receptors, Purinergic; Signal Transduction	2014
High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2015, Volume: 43, Issue:3 Topics: Alendronate; Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Coloring Agents; Diphosphonates; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Humans; Ibandronic Acid; Necrosis; Osteoblasts; Pamidronate; Resting Phase, Cell Cycle; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors	2015
The influence of geranylgeraniol on human oral keratinocytes after bisphosphonate treatment: An in vitro study. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2015, Volume: 43, Issue:5 Topics: Apoptosis; Bone Density Conservation Agents; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Clodronic Acid; Diphosphonates; Diterpenes; Humans; Ibandronic Acid; Imidazoles; Keratinocytes; Mouth Mucosa; Pamidronate; Zoledronic Acid	2015
Bisphosphonates enhance bacterial adhesion and biofilm formation on bone hydroxyapatite. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2015, Volume: 43, Issue:6 Topics: Bacterial Adhesion; Bacteriological Techniques; Biocompatible Materials; Biofilms; Bone and Bones; Bone Density Conservation Agents; Clodronic Acid; Coated Materials, Biocompatible; Diphosphonates; Durapatite; Humans; Hydrogen Bonding; Imidazoles; Microscopy, Electron, Scanning; Pamidronate; Pseudomonas aeruginosa; Staphylococcus aureus; Static Electricity; Streptococcus mutans; X-Ray Microtomography; Zoledronic Acid	2015
[Bisphosphonate use and related pharmaceutical issues II]. Acta pharmaceutica Hungarica, 2016, Volume: 86, Issue:1 Topics: Administration, Oral; Alendronate; Bone Density Conservation Agents; Bone Neoplasms; Clodronic Acid; Confounding Factors, Epidemiologic; Diphosphonates; Drug Costs; Drug Prescriptions; Drugs, Generic; Humans; Hungary; Ibandronic Acid; Imidazoles; National Health Programs; Osteoporosis; Pamidronate; Retrospective Studies; Risedronic Acid; Zoledronic Acid	2016