Compounds > paliperidone
Page last updated: 2024-09-03

paliperidone and su 11248

paliperidone has been researched along with su 11248 in 3 studies

Compound Research Comparison

Studies
(paliperidone)		Trials
(paliperidone)		Recent Studies (post-2010)
(paliperidone)		Studies
(su 11248)		Trials
(su 11248)		Recent Studies (post-2010) (su 11248)
240174,3385603,200

Protein Interaction Comparison

ProteinTaxonomypaliperidone (IC50)su 11248 (IC50)
Serine/threonine-protein kinase Chk1Homo sapiens (human)0.0773
Aurora kinase AHomo sapiens (human)1.837
Solute carrier family 22 member 1 Homo sapiens (human)6.1
NUAK family SNF1-like kinase 1Homo sapiens (human)0.048
Serine/threonine-protein kinase PAK 4Homo sapiens (human)0.5692
Serine/threonine-protein kinase Chk2Homo sapiens (human)0.0168
Tyrosine-protein kinase ABL1Homo sapiens (human)0.8423
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.555
Epidermal growth factor receptorHomo sapiens (human)0.48
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.0186
Insulin receptorHomo sapiens (human)3.2
Tyrosine-protein kinase LckHomo sapiens (human)0.0089
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0888
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.35
Hepatocyte growth factor receptorHomo sapiens (human)4.0002
Tyrosine-protein kinase HCKHomo sapiens (human)0.19
Platelet-derived growth factor receptor betaHomo sapiens (human)0.211
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.2639
Fibroblast growth factor receptor 1Homo sapiens (human)1.4228
AromataseHomo sapiens (human)0.018
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.2764
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.061
Translocator proteinRattus norvegicus (Norway rat)0.039
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.0457
AcetylcholinesteraseHomo sapiens (human)5.87
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)0.0186
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.009
G protein-coupled receptor kinase 5Homo sapiens (human)0.83
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.0089
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.1116
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0581
Casein kinase I isoform alphaHomo sapiens (human)0.001
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.1839
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)0.0617
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.018
Angiopoietin-1 receptorHomo sapiens (human)0.018
Focal adhesion kinase 1Homo sapiens (human)1.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.8389
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)0.158
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)0.1313
AP2-associated protein kinase 1Homo sapiens (human)0.0462
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.0215
Aurora kinase BHomo sapiens (human)1.5
Serine/threonine-protein kinase TBK1Homo sapiens (human)0.22
ALK tyrosine kinase receptorHomo sapiens (human)1.1773
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R1

Reviews

1 review(s) available for paliperidone and su 11248

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for paliperidone and su 11248

ArticleYear
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Development of an
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic

2021