paliperidone has been researched along with olanzapine in 3 studies
Studies (paliperidone) | Trials (paliperidone) | Recent Studies (post-2010) (paliperidone) | Studies (olanzapine) | Trials (olanzapine) | Recent Studies (post-2010) (olanzapine) |
---|---|---|---|---|---|
24 | 0 | 17 | 6,339 | 1,340 | 2,383 |
Protein | Taxonomy | paliperidone (IC50) | olanzapine (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.097 | |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.155 | |
5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.047 | |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.04 | |
Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.541 | |
Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.768 | |
D(2) dopamine receptor | Homo sapiens (human) | 0.118 | |
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.047 | |
Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.421 | |
Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.531 | |
Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.392 | |
D(1A) dopamine receptor | Homo sapiens (human) | 0.072 | |
D(4) dopamine receptor | Homo sapiens (human) | 0.173 | |
Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.092 | |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.038 | |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.021 | |
5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.047 | |
Sodium-dependent serotonin transporter | Homo sapiens (human) | 1.033 | |
Histamine H1 receptor | Homo sapiens (human) | 0.013 | |
D(3) dopamine receptor | Homo sapiens (human) | 0.078 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.057 | |
5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.013 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.158 | |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2028 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Giordanetto, F; Leach, AG; Zachariae, U | 1 |
Sen, S; Sinha, N | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for paliperidone and olanzapine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for paliperidone and olanzapine
Article | Year |
---|---|
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |