Page last updated: 2024-09-03

paliperidone and aripiprazole

paliperidone has been researched along with aripiprazole in 4 studies

Compound Research Comparison

Studies
(paliperidone)
Trials
(paliperidone)
Recent Studies (post-2010)
(paliperidone)
Studies
(aripiprazole)
Trials
(aripiprazole)
Recent Studies (post-2010) (aripiprazole)
240172,9895091,788

Protein Interaction Comparison

ProteinTaxonomypaliperidone (IC50)aripiprazole (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)0.78
D(2) dopamine receptorHomo sapiens (human)0.0158
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.945
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.38
Alpha-1A adrenergic receptorHomo sapiens (human)0.17
Histamine H1 receptorHomo sapiens (human)0.42
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.8572

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Akber Aisa, H; Chen, W; Guo, S; He, Y; Hu, T; Jiang, X; Li, J; Liu, Y; Shen, J; Wang, Y; Wang, Z; Wu, C; Xiamuxi, H; Xie, Y; Xu, M; Yang, F; Zhang, J; Zhao, Q1

Reviews

1 review(s) available for paliperidone and aripiprazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for paliperidone and aripiprazole

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics.
    Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Disease Models, Animal; Dogs; Half-Life; Humans; Inhibitory Concentration 50; Mice; Microsomes, Liver; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Structure-Activity Relationship

2017