Compounds > pak 104p
Page last updated: 2024-09-03

pak 104p and daunorubicin

pak 104p has been researched along with daunorubicin in 3 studies

Compound Research Comparison

Studies
(pak 104p)		Trials
(pak 104p)		Recent Studies (post-2010)
(pak 104p)		Studies
(daunorubicin)		Trials
(daunorubicin)		Recent Studies (post-2010) (daunorubicin)
16008,2398861,310

Protein Interaction Comparison

ProteinTaxonomypak 104p (IC50)daunorubicin (IC50)
72 kDa type IV collagenaseHomo sapiens (human)1.9
Multidrug resistance-associated protein 1 Homo sapiens (human)8
Histone deacetylase 1Homo sapiens (human)0.047
Histone deacetylase 8Homo sapiens (human)0.22
Histone deacetylase 6Homo sapiens (human)0.02

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garnier-Suillerot, A; Marbeuf-Gueye, C; Quidu, P; Salerno, M1
Garnier-Suillerot, A; Salerno, M1
Garnier-Suillerot, A; Loechariyakul, P; Saengkhae, C; Salerno, M1

Other Studies

3 other study(ies) available for pak 104p and daunorubicin

ArticleYear
Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P.
    European journal of pharmacology, 2000, Mar-17, Volume: 391, Issue:3

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclic P-Oxides; Daunorubicin; Depression, Chemical; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Fluoresceins; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Nicotinic Acids; Tumor Cells, Cultured

2000
Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells.
    European journal of pharmacology, 2001, Jun-01, Volume: 421, Issue:1

    Topics: ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Small Cell; Cyclic P-Oxides; Daunorubicin; Dose-Response Relationship, Drug; Extracellular Space; Gene Expression Regulation, Neoplastic; Glutathione; Humans; K562 Cells; Kinetics; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Nicotinic Acids; Propionates; Quinolines; Time Factors; Tumor Cells, Cultured; Vinblastine

2001
Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin.
    Biochemical pharmacology, 2004, Dec-01, Volume: 68, Issue:11

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclic P-Oxides; Daunorubicin; Glutathione; Humans; Nicotinic Acids; Propionates; Quinolines; Tumor Cells, Cultured; Verapamil

2004