paclitaxel has been researched along with zk-219477 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fichtner, I; Hess-Stumpp, H; Hoffmann, J; Hofmann, B; Klar, U; Lemm, M; Lienau, P; Rotgeri, A | 1 |
| Hauff, P; Hoffmann, J; Käkönen, SM; Klar, U; Stepina, E; Strube, A | 1 |
| Halleen, JM; Käkönen, SM; Klar, U; Mumberg, D; Rissanen, JP; Strube, A; Suominen, MI | 1 |
| Eschenbrenner, J; Hammer, S; Hoffmann, J; Klar, U; Mittelstaedt, K; Sommer, A; Winsel, S | 1 |
1 trial(s) available for paclitaxel and zk-219477
| Article | Year |
|---|---|
The anti-tumor agent sagopilone shows antiresorptive effects both in vitro and in vivo.
Topics: Animals; Benzothiazoles; Bone Density; Bone Resorption; Disease Models, Animal; Epothilones; Female; Humans; Mice; Osteoclasts; Osteoporosis; Ovariectomy; Paclitaxel; Tubulin Modulators | 2011 |
3 other study(ies) available for paclitaxel and zk-219477
| Article | Year |
|---|---|
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epothilones; Female; Half-Life; Humans; Male; Mice; Mice, Nude; Paclitaxel; Rats; Rats, Wistar; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays | 2009 |
Sagopilone inhibits breast cancer bone metastasis and bone destruction due to simultaneous inhibition of both tumor growth and bone resorption.
Topics: Acid Phosphatase; Animals; Antineoplastic Agents, Phytogenic; Benzothiazoles; Bone and Bones; Bone Neoplasms; Bone Resorption; Cachexia; Cell Line, Tumor; Dose-Response Relationship, Drug; Epothilones; Female; Humans; Isoenzymes; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Osteoclasts; Osteolysis; Paclitaxel; Tartrate-Resistant Acid Phosphatase; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
Molecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Benzothiazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytoskeleton; DNA Damage; Epothilones; Humans; In Vitro Techniques; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Phenotype; Tumor Suppressor Protein p53; Up-Regulation | 2011 |