paclitaxel and u 0126
paclitaxel has been researched along with u 0126 in 18 studies
Research
Studies (18)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (77.78) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Collins, TS; MacKeigan, JP; Ting, JP | 1 |
| Horwitz, SB; McDaid, HM | 1 |
| Horwitz, SB; Yang, CP | 1 |
| Earp, HS; Graves, LM; Hunter, D; MacKeigan, JP; Taxman, DJ; Ting, JP | 1 |
| Bally, M; Dragowska, WH; Hu, Y; Mayer, L | 1 |
| Bergstralh, DT; Clements, C; MacKeigan, JP; Taxman, DJ; Ting, JP | 1 |
| Davis, TL; Hauke, R; Kakitelashvilli, V; Kellerman, M; Lee, MS; Lin, MF; Lugo, E; Spellman, M; Taylor, R; Zelivianski, S; Zhou, XW | 1 |
| Clements, CM; Hod, Y; Lich, JD; MacKeigan, JP; Pope, RM; Ting, JP | 1 |
| Chen, DY; Gao, WX; Hou, Y; Huo, LJ; Liu, K; Liu, XJ; Schatten, H; Sun, QY; Wang, CM; Wang, Q; Xiong, B; Yu, LZ; Zhong, ZS | 1 |
| Abudukadier, K; Pentassuglia, L; Seifriz, F; Suter, TM; Timolati, F; Zuppinger, C | 1 |
| Katayama, K; Mitsuhashi, J; Sugimoto, Y; Tsukahara, S; Yoshioka, S | 1 |
| Bachman, KE; Martin, SS; Park, BH; Szmacinski, M; Tahir, K; Vitolo, MI; Waldman, T; Weber, DJ; Weiss, MB | 1 |
| Abrams, SL; Bäsecke, J; Chappell, W; Donia, M; Libra, M; Martelli, AM; McCubrey, JA; Nicoletti, F; Shelton, JG; Steelman, LS; Stivala, F | 1 |
| Corey, SJ; Park, BJ; Whichard, ZL | 1 |
| Al-Azzam, SI; Alsaad, AA; Alzoubi, KH; Mhaidat, NM | 1 |
| Budach, W; Hüsemann, LC; Jänicke, RU; Piekorz, RP; Radine, C; Reese, A; Sohn, D | 1 |
Other Studies
18 other study(ies) available for paclitaxel and u 0126
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
MEK inhibition enhances paclitaxel-induced tumor apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butadienes; Cell Cycle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Flow Cytometry; Genes, Dominant; Histones; Humans; Immunoblotting; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Tumor Cells, Cultured | 2000 |
Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Butadienes; CHO Cells; Cricetinae; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; HeLa Cells; Humans; Microtubules; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Transcription Factors; Tumor Cells, Cultured | 2001 |
Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antineoplastic Agents, Phytogenic; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Proteins; Pyridines; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Tumor Necrosis Factor-alpha | 2002 |
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Northern; Butadienes; Chromones; Drug Therapy, Combination; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neuregulin-1; Nitriles; Paclitaxel; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Butadienes; Carcinoma, Non-Small-Cell Lung; Caspases; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Enzyme Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Staurosporine; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Transcriptional profiling of targets for combination therapy of lung carcinoma with paclitaxel and mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butadienes; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dactinomycin; Enzyme Inhibitors; Female; Gene Expression Profiling; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Melanoma; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Paclitaxel | 2003 |
ERK inhibitor PD98059 enhances docetaxel-induced apoptosis of androgen-independent human prostate cancer cells.
Topics: Apoptosis; bcl-X Protein; Butadienes; Docetaxel; Drug Synergism; Enzyme Inhibitors; Flavonoids; Humans; Male; Mitogen-Activated Protein Kinases; Neoplasms, Hormone-Dependent; Nitriles; Paclitaxel; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Taxoids; Tumor Cells, Cultured; Vinblastine; Vinorelbine | 2003 |
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Enzyme Inhibitors; Guanine Nucleotide Dissociation Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinase 1; Nitriles; Oncogene Proteins; Paclitaxel; Protein Deglycase DJ-1; Protein Serine-Threonine Kinases; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; rho-Specific Guanine Nucleotide Dissociation Inhibitors | 2003 |
MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation.
Topics: Animals; Butadienes; Female; Fluorescent Antibody Technique; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Meiosis; Mice; Mice, Inbred ICR; Microscopy, Confocal; Microtubules; Nitriles; Nocodazole; Oocytes; Oogenesis; Paclitaxel; Phosphorylation; RNA Interference; Spindle Apparatus | 2007 |
Inhibition of ErbB2/neuregulin signaling augments paclitaxel-induced cardiotoxicity in adult ventricular myocytes.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Butadienes; Cell Survival; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycoproteins; Heart Ventricles; Male; Microtubules; Myocardial Contraction; Myocytes, Cardiac; Myofibrils; Nitriles; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Signal Transduction | 2007 |
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butadienes; Cell Line, Tumor; Down-Regulation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Humans; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rhodamine 123; RNA Interference; Time Factors; Transcription, Genetic; Up-Regulation | 2007 |
Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells.
Topics: Anoikis; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Butadienes; Cell Proliferation; Cell Transformation, Neoplastic; Chromones; Doxorubicin; Enzyme Inhibitors; Epithelial Cells; Female; Flow Cytometry; Humans; Integrases; Mammary Glands, Human; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2009 |
Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Butadienes; Cell Line, Tumor; Chromones; Doxorubicin; G1 Phase; Interleukin-3; Intracellular Signaling Peptides and Proteins; Leukemia, Prolymphocytic; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nitriles; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2010 |
Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Breast Neoplasms; Butadienes; Cell Line, Tumor; Chromones; Dasatinib; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epothilones; Female; Humans; Morpholines; Niacinamide; Nitriles; Paclitaxel; Phenylurea Compounds; Pyridines; Pyrimidines; Signal Transduction; Sirolimus; Sorafenib; Tamoxifen; Thiazoles | 2012 |
Caffeine inhibits paclitaxel‑induced apoptosis in colorectal cancer cells through the upregulation of Mcl‑1 levels.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Butadienes; Caffeine; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Endoplasmic Reticulum Chaperone BiP; Extracellular Signal-Regulated MAP Kinases; Heat-Shock Proteins; Humans; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Nitriles; Paclitaxel; Signal Transduction; Up-Regulation | 2014 |
The microtubule targeting agents eribulin and paclitaxel activate similar signaling pathways and induce cell death predominantly in a caspase-independent manner.
Topics: Anthracenes; Butadienes; Caspase 3; Cell Cycle; Cell Death; Cell Line, Tumor; Furans; Humans; Ketones; Microtubules; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2020 |