Page last updated: 2024-08-23

paclitaxel and serine

paclitaxel has been researched along with serine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (12.50)	18.2507
2000's	22 (55.00)	29.6817
2010's	13 (32.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Basu, A; Croce, CM; Haldar, S	1
Basu, A; Haldar, S	1
Hardwick, JM; Longo, DL; Mi, QS; Srivastava, RK	1
Fuji, K; Hamajima, Y; Kohno, M; Nuruzzaman, M; Ohtsubo, T; Watanabe, Y	1
Ichijo, H; Korsmeyer, SJ; Yamamoto, K	1
Jenkins, SM; Johnson, GV	1
Horwitz, SB; Yang, CP	2
Bornens, M; Gavet, O; Küntziger, T; Manceau, V; Sobel, A	1
Pietenpol, JA; Stewart, ZA; Tang, LJ	1
Daniewski, WM; Grabarczyk, H; Gumulka, M; Kopczacki, P; Masnyk, M; Nowak, G	1
Matsuo, Y; Shibasaki, F; Shibata, M; Shitashige, M; Toi, M; Yano, T	1
Fan, W; Huang, Y	1
Briand, C; Devred, F; Douillard, S; Peyrot, V	1
Bast, RC; Hittelman, WN; Le, XF; Li, C; Liu, J; McWatters, A; Mills, GB	1
Arimoto-Ishida, E; Kimura, A; Mabuchi, S; Murata, Y; Nishio, Y; Ohmichi, M; Tasaka, K; Yada-Hashimoto, N	1
Asnaghi, L; Bevilacqua, A; Calastretti, A; Canti, G; Capaccioli, S; D'Agnano, I; Delia, D; Gatti, G; Nicolin, A	1
Galeazzi, R; Martelli, G; Mobbili, G; Orena, M; Rinaldi, S	1
Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA	1
Colomer, R; Lupu, R; Menendez, JA; Vellon, L	1
Alappat, EC; Boyerinas, B; Feig, C; Kidd, VJ; Murmann, AE; Osborn, SL; Peter, ME; Samuels, M; Slaughter, CA; Tang, WJ; Thorburn, A; Volkland, J; Winoto, A	1
Dzieciatkowski, T; Kniotek, M; Krawczyk, E; Luczak, M; Majewska, A; Nowaczyk, M; Przybylski, M	1
Buscemi, G; Carlessi, L; Delia, D; Hong, Z; Larson, G; Wu, JZ	1
Casado, P; Iglesias, JM; Lazo, PS; Martínez-Campa, C; Prado, MA; Ramos, S; Valle, ED; Zuazua-Villar, P	1
Brautigan, DL; Stukenberg, PT; Wang, W	1
Chabalier-Taste, C; Dozier, C; Larminat, F; Racca, C	1
Itoh, K; Muranaka, T; Tachinbana, S	1
Costantino, JP; Jeong, JH; Kidwell, K; Kim, C; Mamounas, EP; Nguyen, D; Paik, S; Swain, SM; Wolmark, N; Yang, SX	1
Dobrowolski, JC; Rode, JE; Sadlej, J	1
Kawamata, T; Kiya, T; Namiki, A; Yamakage, M	1
Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W	1
Akoumianaki, T; Black, EJ; Gillespie, DA; Petsalaki, E; Zachos, G	1
Evan, GI; MacFhearraigh, S; Mc Gee, MM; O'Donovan, DS; Swigart, LB; Whitfield, J	1
Kawamata, T; Kiya, T	1
Beauchemin, M; Bertrand, R; Wang, J	1
Bahleda, R; Capri, G; Daglish, B; Del Conte, G; Gianni, L; Hospitel, M; Oprea, C; Sessa, C; Soria, JC; Varga, A	1
Armstrong, DW; Forró, E; Fülöp, F; Grecsó, N; Ilisz, I; Péter, A	1
Magan, N; Medina, A; Somjaipeng, S	1
Janicki, M; Lozynski, M	1
Chen, X; Lan, L; Liu, Y; Lu, B; Lu, Y; Mo, S; Wei, W; Wu, X; Zhang, F; Zhang, X	1

Trials

2 trial(s) available for paclitaxel and serine

Article	Year
Akt phosphorylation at Ser473 predicts benefit of paclitaxel chemotherapy in node-positive breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-20, Volume: 28, Issue:18 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Serine; Tissue Array Analysis; Treatment Outcome	2010
Phase I clinical and pharmacokinetic study of ombrabulin (AVE8062) combined with cisplatin/docetaxel or carboplatin/paclitaxel in patients with advanced solid tumors. Investigational new drugs, 2014, Volume: 32, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Docetaxel; Drug Interactions; Female; Humans; Male; Middle Aged; Neoplasms; Paclitaxel; Response Evaluation Criteria in Solid Tumors; Serine; Taxoids; Young Adult	2014

Article

Year

Akt phosphorylation at Ser473 predicts benefit of paclitaxel chemotherapy in node-positive breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-20, Volume: 28, Issue:18

Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Serine; Tissue Array Analysis; Treatment Outcome

2010

Phase I clinical and pharmacokinetic study of ombrabulin (AVE8062) combined with cisplatin/docetaxel or carboplatin/paclitaxel in patients with advanced solid tumors.

Investigational new drugs, 2014, Volume: 32, Issue:6

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Docetaxel; Drug Interactions; Female; Humans; Male; Middle Aged; Neoplasms; Paclitaxel; Response Evaluation Criteria in Solid Tumors; Serine; Taxoids; Young Adult

2014

Other Studies

38 other study(ies) available for paclitaxel and serine

Article	Year
Serine-70 is one of the critical sites for drug-induced Bcl2 phosphorylation in cancer cells. Cancer research, 1998, Apr-15, Volume: 58, Issue:8 Topics: Alanine; Antineoplastic Agents; Apoptosis; Depsipeptides; Humans; Mutagenesis, Site-Directed; Nocodazole; Okadaic Acid; Oligopeptides; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Tumor Cells, Cultured	1998
Microtubule-damaging drugs triggered bcl2 phosphorylation-requirement of phosphorylation on both serine-70 and serine-87 residues of bcl2 protein. International journal of oncology, 1998, Volume: 13, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Binding Sites; Colchicine; Demecolcine; Enzyme Inhibitors; Gout Suppressants; Humans; Lactams, Macrocyclic; Microtubules; Mutagenesis, Site-Directed; Paclitaxel; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Quinones; Serine; Tumor Cells, Cultured	1998
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-30, Volume: 96, Issue:7 Topics: Alanine; Amino Acid Substitution; Apoptosis; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mitochondria; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Paclitaxel; Phosphorylation; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Sequence Deletion; Serine; Signal Transduction; Transfection; Tumor Cells, Cultured; Vincristine	1999
Synthesis of extremely simplified compounds possessing the key pharmacophore units of taxol, phenylisoserine and oxetane moieties. Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:9 Topics: Alcohols; Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry, Physical; Ethers, Cyclic; Magnetic Resonance Spectroscopy; Paclitaxel; Serine; Tubulin	1999
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Molecular and cellular biology, 1999, Volume: 19, Issue:12 Topics: Amino Acid Sequence; Apoptosis; Binding Sites; CDC2 Protein Kinase; Cyclin B; Cyclin B1; Enzyme Activation; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 7; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Microtubules; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitosis; Molecular Sequence Data; Mutagenesis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Threonine	1999
Microtubule/MAP-affinity regulating kinase (MARK) is activated by phenylarsine oxide in situ and phosphorylates tau within its microtubule-binding domain. Journal of neurochemistry, 2000, Volume: 74, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenicals; Binding Sites; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Microtubules; Neuroblastoma; Neurons; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rats; Serine; tau Proteins; Tumor Cells, Cultured	2000
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform. Cancer research, 2000, Sep-15, Volume: 60, Issue:18 Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents, Phytogenic; Carcinoma; Cyanogen Bromide; Cycloheximide; Drug Interactions; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Flavonoids; Humans; Lung Neoplasms; MAP Kinase Kinase Kinases; Microtubules; Paclitaxel; Peptide Fragments; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-raf; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tumor Cells, Cultured; Tyrosine	2000
Stathmin/Op18 phosphorylation is regulated by microtubule assembly. Molecular biology of the cell, 2001, Volume: 12, Issue:2 Topics: Animals; Cell Nucleus; Centrosome; Enzyme Inhibitors; Female; HeLa Cells; Humans; Interphase; Male; Microtubule Proteins; Microtubules; Nocodazole; Ovum; Paclitaxel; Phosphoproteins; Phosphorylation; Protein Isoforms; Serine; Spermatozoa; Stathmin; Xenopus; Xenopus Proteins	2001
Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner. Oncogene, 2001, Jan-04, Volume: 20, Issue:1 Topics: Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Humans; Microtubules; Mutagenesis, Site-Directed; Paclitaxel; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vincristine	2001
Synthesis and antifeedant properties of N-benzoylphenylisoserinates of Lactarius sesquiterpenoid alcohols. Phytochemistry, 2001, Volume: 58, Issue:5 Topics: Agaricales; Animals; Feeding Behavior; Paclitaxel; Serine; Sesquiterpenes; Trematoda; Tribolium	2001
Dissociation of Bax from a Bcl-2/Bax heterodimer triggered by phosphorylation of serine 70 of Bcl-2. Journal of biochemistry, 2001, Volume: 130, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Burkitt Lymphoma; Cell Line; Cell Survival; Cricetinae; Cytochrome c Group; Dimerization; Fibroblasts; Humans; Kidney; Mesocricetus; Mitochondria; Paclitaxel; Phosphorylation; Protein Binding; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Serine; Tumor Cells, Cultured	2001
IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines. Molecular pharmacology, 2002, Volume: 61, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA-Binding Proteins; Enzyme Activation; Humans; I-kappa B Kinase; I-kappa B Proteins; MAP Kinase Kinase Kinase 1; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Phosphorylation; Prohibitins; Protein Serine-Threonine Kinases; Serine; Transfection; Tumor Cells, Cultured; Up-Regulation	2002
Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells. Biochimica et biophysica acta, 2002, Jun-12, Volume: 1590, Issue:1-3 Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antineoplastic Agents, Phytogenic; Butadienes; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Proteins; Pyridines; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Tumor Necrosis Factor-alpha	2002
First tau repeat domain binding to growing and taxol-stabilized microtubules, and serine 262 residue phosphorylation. FEBS letters, 2002, Jul-17, Volume: 523, Issue:1-3 Topics: Animals; Binding Sites; Kinetics; Microtubules; Paclitaxel; Peptides; Phosphorylation; Repetitive Sequences, Nucleic Acid; Serine; Swine; tau Proteins; Thermodynamics; Tubulin	2002
Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis. Oncogene, 2003, Jan-30, Volume: 22, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium; Humans; Isoenzymes; Mitogen-Activated Protein Kinases; Mitosis; Paclitaxel; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Type C Phospholipases	2003
Estrogen inhibits paclitaxel-induced apoptosis via the phosphorylation of apoptosis signal-regulating kinase 1 in human ovarian cancer cell lines. Endocrinology, 2004, Volume: 145, Issue:1 Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Estrogens; Female; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Receptors, Estrogen; Serine	2004
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene, 2004, Jul-29, Volume: 23, Issue:34 Topics: Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; G2 Phase; Microtubules; Mitosis; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2004
Stereoselective iodocyclization of 3-acylamino-2-methylene alkanoates: synthesis of analogues of N-benzoyl-syn-phenylisoserine. Organic letters, 2004, Jul-22, Volume: 6, Issue:15 Topics: Alkanes; Benzene Derivatives; Cyclization; Iodine; Molecular Structure; Paclitaxel; Serine; Stereoisomerism	2004
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants. Biochemistry, 2004, Dec-14, Volume: 43, Issue:49 Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone	2004
Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity. International journal of cancer, 2005, May-20, Volume: 115, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cytoplasm; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Fatty Acid Synthases; Gene Silencing; Histones; Humans; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Nucleosomes; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Protein Structure, Tertiary; RNA Interference; RNA, Small Interfering; Serine	2005
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities. Molecular cell, 2005, Aug-05, Volume: 19, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Casein Kinase Ialpha; Cell Cycle; Cell Line; Cell Nucleus; Concanavalin A; Cytosol; Enzyme Inhibitors; Fas-Associated Death Domain Protein; HeLa Cells; Humans; Isoquinolines; Jurkat Cells; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitosis; Molecular Sequence Data; Mutation; Paclitaxel; Phosphorylation; Protein Binding; Protein Transport; RNA, Small Interfering; Sequence Homology, Amino Acid; Serine; Spindle Apparatus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection	2005
N-acetylphenylisoserinates of Lactarius sesquiterpenoid alcohols--cytotoxic, antiviral, antiproliferative and immunotropic activities in vitro. Planta medica, 2006, Volume: 72, Issue:7 Topics: Agaricales; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antiviral Agents; Cell Proliferation; Chlorocebus aethiops; Esterification; Herpesvirus 1, Human; Paclitaxel; Serine; Sesquiterpenes; T-Lymphocytes; Vero Cells	2006
Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2. Molecular cancer therapeutics, 2007, Volume: 6, Issue:3 Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Benzimidazoles; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Inhibitors; Humans; Immunoprecipitation; Mice; Molecular Structure; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Recombinant Proteins; Serine; Thiazoles; Threonine; Tumor Suppressor Proteins	2007
Characterization of HSP27 phosphorylation induced by microtubule interfering agents: implication of p38 signalling pathway. Archives of biochemistry and biophysics, 2007, May-01, Volume: 461, Issue:1 Topics: Cell Line, Tumor; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Microtubules; Molecular Chaperones; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Serine; Tubulin Modulators; Vincristine	2007
Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. Molecular biology of the cell, 2008, Volume: 19, Issue:11 Topics: Aurora Kinase B; Aurora Kinases; Cell Line; Cell Nucleus; Centrosome; Chromosome Segregation; Cytokinesis; Epithelial Cells; Histones; Humans; Indoles; Mitosis; Models, Biological; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Transport; Proteins; Retina; RNA Interference; Serine; Spindle Apparatus; Sulfonamides	2008
BRCA1 is regulated by Chk2 in response to spindle damage. Biochimica et biophysica acta, 2008, Volume: 1783, Issue:12 Topics: Blotting, Western; BRCA1 Protein; Cell Survival; Centrosome; Checkpoint Kinase 2; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoprecipitation; Microtubules; Mitosis; Mitotic Index; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; RNA, Small Interfering; Serine; Spindle Apparatus; Tubulin Modulators; Tumor Cells, Cultured	2008
Effect of elicitors and a biogenetic precursor on paclitaxel production in cell suspension cultures of Taxus cuspidata var. nana. Pakistan journal of biological sciences : PJBS, 2007, Sep-01, Volume: 10, Issue:17 Topics: Antineoplastic Agents, Phytogenic; Carbohydrates; Cell Culture Techniques; Chemistry, Pharmaceutical; Culture Media; Cyclopentanes; Oxylipins; Paclitaxel; Serine; Taxus	2007
Phenylisoserine in the gas-phase and water: Ab initio studies on neutral and zwitterion conformers. Journal of molecular modeling, 2011, Volume: 17, Issue:5 Topics: Acid-Base Equilibrium; Antineoplastic Agents; Drug Design; Gases; Humans; Hydrogen Bonding; Isomerism; Models, Molecular; Molecular Conformation; Neoplasms; Paclitaxel; Quantum Theory; Serine; Temperature; Thermodynamics; Water	2011
Role of satellite cell-derived L-serine in the dorsal root ganglion in paclitaxel-induced painful peripheral neuropathy. Neuroscience, 2011, Feb-03, Volume: 174 Topics: Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Ganglia, Spinal; Hyperalgesia; Male; Neural Conduction; Paclitaxel; Pain; Peripheral Nervous System Diseases; Phosphoglycerate Dehydrogenase; Rats; Rats, Sprague-Dawley; Satellite Cells, Perineuronal; Serine; Stereoisomerism; Tail; Touch	2011
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells. Journal of the National Cancer Institute, 2011, Sep-21, Volume: 103, Issue:18 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays	2011
Phosphorylation at serine 331 is required for Aurora B activation. The Journal of cell biology, 2011, Oct-31, Volume: 195, Issue:3 Topics: Amino Acid Sequence; Animals; Aurora Kinase B; Aurora Kinases; CHO Cells; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Cricetinae; Enzyme Activation; Humans; Kinetochores; Microscopy, Fluorescence; Mitosis; Molecular Sequence Data; Paclitaxel; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Serine	2011
Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death. Cell death & disease, 2013, Jan-24, Volume: 4 Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Cycle Proteins; Cyclin B1; Humans; Immunoprecipitation; K562 Cells; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins; Recombinant Proteins; Serine	2013
[Role of satellite cell-derived L-serine in the dorsal root ganglion in paclitaxel-induced peripheral neuropathy]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2013, Volume: 141, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Ganglia, Spinal; Humans; Hyperalgesia; Paclitaxel; Peripheral Nervous System Diseases; Rats; Satellite Cells, Perineuronal; Serine	2013
Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosis. Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:8 Topics: bcl-X Protein; Cell Cycle Proteins; Chromosome Segregation; HeLa Cells; Humans; M Phase Cell Cycle Checkpoints; Microtubules; Mitogen-Activated Protein Kinase 14; Mitosis; Mutation; Nocodazole; Paclitaxel; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Serine; Signal Transduction; Tubulin Modulators	2014
High-performance liquid chromatographic separation of paclitaxel intermediate phenylisoserine derivatives on macrocyclic glycopeptide and cyclofructan-based chiral stationary phases. Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114 Topics: Alcohols; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Entropy; Fructans; Glycopeptides; Hot Temperature; Hydrogen-Ion Concentration; Paclitaxel; Peptides; Serine; Stereoisomerism	2015
Environmental stress and elicitors enhance taxol production by endophytic strains of Paraconiothyrium variabile and Epicoccum nigrum. Enzyme and microbial technology, 2016, Volume: 90 Topics: Antineoplastic Agents, Phytogenic; Ascomycota; Culture Media; Endophytes; Hydrogen-Ion Concentration; Paclitaxel; Salicylic Acid; Serine; Stress, Physiological; Taxus	2016
Toward an ab initio potential energy surface for paclitaxel: A C-13 isoserine side chain conformational study. Journal of molecular graphics & modelling, 2017, Volume: 73 Topics: Hydrogen Bonding; Models, Molecular; Molecular Conformation; Paclitaxel; Serine; Thermodynamics	2017
Paclitaxel induces apoptosis of esophageal squamous cell carcinoma cells by downregulating STAT3 phosphorylation at Ser727. Oncology reports, 2017, Volume: 37, Issue:4 Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Mitochondria; Paclitaxel; Phosphorylation; Serine; STAT3 Transcription Factor	2017