Page last updated: 2024-08-23

paclitaxel and pyrazolanthrone

paclitaxel has been researched along with pyrazolanthrone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Koller, E; Marietta, PM; Mingo-Sion, AM; Van Den Berg, CL; Wolf, DM1
Chambers, TC; Kolomeichuk, SN; Lyle, CS; Sabapathy, K; Terrano, DT1
Hendricks, M; Jesuthasan, S1
Huang, H; Lo, WY; Lu, TL; Wang, HJ1
Bates, DJ; Eastman, A; Lowrey, CH; Salerni, BL1
Ahn, YH; Jee, HG; Kim, HR; Kim, JB; Kim, YJ; Lee, HS; Lee, JH; Lee, M; Park, SY; Yoon, JH; Yu, SJ1
Bedalov, CO; Prosperi, JR; Soto, KF; VanKlompenberg, MK1
Kitanaka, C; Kurachi, H; Kuramoto, K; Nagase, S; Ohta, T; Okada, M; Sakaki, H; Seino, M; Seino, S; Suzuki, S; Takeda, H; Watarai, H1
Budach, W; Hüsemann, LC; Jänicke, RU; Piekorz, RP; Radine, C; Reese, A; Sohn, D1

Other Studies

12 other study(ies) available for paclitaxel and pyrazolanthrone

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells.
    Oncogene, 2004, Jan-15, Volume: 23, Issue:2

    Topics: Anthracenes; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; DNA Replication; Doxorubicin; G2 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mitosis; Oligonucleotides, Antisense; Paclitaxel; Tumor Suppressor Protein p53; Ultraviolet Rays

2004
Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively.
    The FEBS journal, 2008, Volume: 275, Issue:8

    Topics: Active Transport, Cell Nucleus; Animals; Anthracenes; Apoptosis; Cell Line; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Microtubules; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Vinblastine

2008
PHR regulates growth cone pausing at intermediate targets through microtubule disassembly.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, May-20, Volume: 29, Issue:20

    Topics: Animals; Anthracenes; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Death-Associated Protein Kinases; Dose-Response Relationship, Drug; Electroporation; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Growth Cones; Imidazoles; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mice, Transgenic; Microtubules; Neurons; Nocodazole; Paclitaxel; Phosphorylation; Prosencephalon; Pyridines; Signal Transduction; Spinal Cord; Tubulin Modulators; Zebrafish; Zebrafish Proteins

2009
(-)-Epigallocatechin-3-gallate decreases thrombin/paclitaxel-induced endothelial tissue factor expression via the inhibition of c-Jun terminal NH2 kinase phosphorylation.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: Anthracenes; Catechin; Cells, Cultured; Drug-Eluting Stents; Endothelium, Vascular; Humans; JNK Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Thrombin; Thromboplastin; Transcription Factor RelA

2010
Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.
    Cancer biology & therapy, 2011, Aug-15, Volume: 12, Issue:4

    Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclic N-Oxides; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; HL-60 Cells; Humans; Immunoblotting; Indolizines; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Myeloid Cell Leukemia Sequence 1 Protein; Paclitaxel; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridinium Compounds; U937 Cells; Vinblastine

2011
JNK signaling in hepatocarcinoma cells is associated with the side population upon treatment with anticancer drugs.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Anthracenes; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; Liver Neoplasms; MAP Kinase Kinase 4; MAP Kinase Signaling System; Paclitaxel; Proto-Oncogene Proteins c-jun; Side-Population Cells

2015
APC selectively mediates response to chemotherapeutic agents in breast cancer.
    BMC cancer, 2015, Jun-07, Volume: 15

    Topics: Adenomatous Polyposis Coli Protein; Animals; Anthracenes; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 4; Mice; Mice, Transgenic; Paclitaxel; Pyrimidines; src-Family Kinases

2015
Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Ovarian Neoplasms; Paclitaxel

2016
The microtubule targeting agents eribulin and paclitaxel activate similar signaling pathways and induce cell death predominantly in a caspase-independent manner.
    Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:4

    Topics: Anthracenes; Butadienes; Caspase 3; Cell Cycle; Cell Death; Cell Line, Tumor; Furans; Humans; Ketones; Microtubules; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2020