Page last updated: 2024-08-23

paclitaxel and phenyl acetate

paclitaxel has been researched along with phenyl acetate in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.72)18.7374
1990's9 (15.52)18.2507
2000's23 (39.66)29.6817
2010's24 (41.38)24.3611
2020's1 (1.72)2.80

Authors

AuthorsStudies
Osgood, C; Sehgal, A; Zimmering, S1
Baas, PW; Black, MM; Humphries, S1
Chirlian, LE; Heerding, JM; Moyna, G; Scott, AI; Swindell, CS; Williams, DK; Williams, HJ1
Beijnen, JH; Huizing, MT; Pinedo, HM; Rosing, H; Sparreboom, A; van Tellingen, O1
Hara, Y; Higashi, Y; Tabata, H; Yukimune, Y1
Schuler, ML1
Croteau, R; Hefner, J; Ketchum, RE1
Croteau, RB; Gibson, DM; Ketchum, RE; Shuler, ML1
Bernard, S; van Deventer, H1
Begley, T; Gibson, DM; Ketchum, RE; Shuler, ML; Tandon, M1
Hara, Y; Nomura, E; Seto, H; Yoshida, S; Yukimune, Y1
Haigh, JR; Linden, JC; Mirjalili, N; Phisaphalong, M1
Balasubramanian, SV; Bigwarfe, PM; Fetterly, GJ; Lorenz, SA; Straubinger, RM; Wood, TD1
Bonfill, M; Cusidó, RM; Morales, C; Palazón, J; Piñol, MT1
Lin, L; Wu, J1
Lawrence, HJ; Nguyen, VH1
Cheng, KD; Zhang, LP; Zhu, P1
Gaman, EA; Gleeson, JP; Obach, RS; Proctor, WR; Walsky, RL1
Wang, JW; Wu, JY1
Dadpour, MR; Ghasempour, A; Khosroushahi, AY; Khosrowshahli, M; Naghdibadi, H; Omidi, Y; Valizadeh, M1
Gibson, DM; Kim, BJ; Shuler, ML1
Gaucher, G; Leroux, JC; Poreba, M; Ravenelle, F1
Lu, SH; Yang, S; Yuan, YJ1
Albrecht, W; Laufer, S; Nussler, AK; Unger, A1
Chakravarty, G; Honer Zu Bentrup, K; Mondal, D; Roy, U1
Barradas-Dermitz, DM; Hayward-Jones, PM; Mata-Rosas, M; Palmeros-Sánchez, B; Platas-Barradas, OB; Velásquez-Toledo, RF1
Gaurav, V; Kolewe, ME; Roberts, SC1
Foti, RS; Rock, DA; VandenBrink, BM; Wahlstrom, JL; Wienkers, LC1
Kolewe, ME; Normanly, J; Patil, RA; Roberts, SC; Walker, EL1
Boutaoui, N; Lenka, SK; Normanly, J; Paulose, B; Roberts, SC; Vongpaseuth, K; Walker, EL1
Fu, C; Li, S; Yu, L; Zhang, M; Zhang, P1
Dong, YS; Fu, CH; Guo, AY; Li, ST; Yu, LJ; Zhang, M; Zhang, P; Zhao, CF1
Bonfill, M; Cusidó, RM; Hernández-Vázquez, L; Moyano, E; Onrubia, M; Palazon, J; Ramirez, K1
Liu, H; Qiu, D; Sun, G; Tang, Q; Wen, JF; Wilson, IW; Wu, J; Xie, F; Yang, Y1
Baek, KH; Hasan, MM; Jeon, JH; Kim, HS; Kim, SH; Moon, B; Shim, SH; Song, JY1
Lenka, SK; Normanly, J; Patil, RA; Roberts, SC; Walker, EL1
Chen, X; Dai, J; Jin, J; Li, Y; Mei, M; Xie, D; You, F; Zhang, Y1
Bonfill, M; Cusido, RM; Eibl, R; Gallego, A; Imseng, N; Moyano, E; Palazon, J1
Chen, Y; Chen, ZS; El Sayed, KA; Jain, S; Li, J; Vispute, SG; Wang, YJ; Youssef, DT; Zhang, Y; Zhang, YK1
Chen, Z; Clinton, SK; Huang, J; Jin, VX; Lan, X; Liu, Z; Sunkel, B; Wang, Q; Wu, D; Ye, Z1
Fang, ZY; Guo, MH; Jin, D; Xu, C; Zhang, L; Zhang, YW1
Chantharasamee, J; Ithimakin, S; Singsuksawat, E; Sootichote, R; Thuwajit, C; Thuwajit, P; Warnnissorn, M; Yenchitsomanus, PT1
El-Kashef, H; El-Maali, NA; Gamal, K; Mohrram, AM1
Ariyanto, EF; Atmaja, H; Aulia, Y; Bashari, MH; Fadhil, M; Indrati, AR; Putri, T; Qomarilla, N; Rohmawaty, E; Sari, AK; Sudji, IR1
Croteau, RB; Ketchum, RE; Kim, YS; Qiu, D; Rithner, CD; Williams, RM1
Christiansen, E; Franceschi, VR; Hudgins, JW1
Dai, JG; Guo, DA; Guo, HZ; Zhan, JX; Zhang, YX; Zhong, JJ; Zhu, WH1
Qian, X; Qian, ZG; Xu, Y; Zhao, ZJ; Zhong, JJ1
Cao, Y; Han, X; Hou, R; Huang, Z; Jiang, K; Liao, Z; Pi, Y; Sun, X; Tang, K; Wang, Q1
Li, F; Liu, M; Pan, X; Qiu, D; Teng, W; Wilson, IW; Zhang, B1
Dai, D; Dai, Y; Jin, Y; Kong, L; Li, W; Qin, Q; Tang, K; Zha, X1
Furmanowa, M; Kokoszka, A; Pietrosiuk, A; Syklowska-Baranek, K1
Gao, M; Yu, X; Zhang, W1
Chen, X; Gu, J; Huang, M; Yin, D; Zhang, M; Zhao, X1
Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J1
Artanti, N; Kardono, LB; Sukiman, H; Tachibana, S1
Bonfill, M; Cusidó, RM; Moyano, E; Onrubia, M; Palazón, J; Pedreño, MA; Sabater-Jara, AB1
Deyou, Q; Duanfen, C; Hongwei, L; Kaikai, Z; Liying, Y; Qiang, L; Xing, L; Yanfang, Y; Ying, W1

Reviews

3 review(s) available for paclitaxel and phenyl acetate

ArticleYear
Gas concentration effects on secondary metabolite production by plant cell cultures.
    Advances in biochemical engineering/biotechnology, 2001, Volume: 72

    Topics: Acetates; Antimalarials; Antineoplastic Agents, Phytogenic; Artemisinins; Carbon Dioxide; Cell Culture Techniques; Cyclopentanes; Drugs, Chinese Herbal; Ethylenes; Humans; Molecular Structure; Oxygen; Oxylipins; Paclitaxel; Plant Cells; Plant Extracts; Plant Growth Regulators; Plants; Sesquiterpenes

2001
[Biotransformation of taxanes].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:2

    Topics: Acetates; Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Diterpenes; Paclitaxel; Taxoids

2004
Bioprocessing of plant in vitro systems for the mass production of pharmaceutically important metabolites: paclitaxel and its derivatives.
    Current medicinal chemistry, 2013, Volume: 20, Issue:7

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Biotechnology; Cyclopentanes; Metabolic Engineering; Microtubules; Oxylipins; Paclitaxel; Plant Cells; Taxoids; Taxus

2013

Other Studies

55 other study(ies) available for paclitaxel and phenyl acetate

ArticleYear
Aneuploidy in Drosophila. III: Aneuploidogens inhibit in vitro assembly of taxol-purified Drosophila microtubules.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:4

    Topics: Acetates; Acetonitriles; Acrylonitrile; Alkaloids; Aneuploidy; Animals; Cadmium; Cadmium Chloride; Colchicine; Dimethyl Sulfoxide; Drosophila melanogaster; Griseofulvin; Mice; Microscopy, Electron; Microtubules; Nitriles; Paclitaxel; Spectrum Analysis; Time Factors

1990
Dynamics of alpha-tubulin deacetylation in intact neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:1

    Topics: Acetates; Acetylation; Alkaloids; Animals; Azides; Cytoskeleton; Isomerism; Microtubules; Neurons; Paclitaxel; Podophyllotoxin; Polymers; Tubulin

1989
NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Acetates; Alkaloids; Chloroform; Deuterium; Dimethyl Sulfoxide; Docetaxel; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Microtubules; Models, Molecular; Molecular Conformation; Molecular Structure; Paclitaxel; Taxoids

1996
Quantification of paclitaxel metabolites in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1995, Dec-15, Volume: 674, Issue:2

    Topics: Acetates; Acetonitriles; Antineoplastic Agents, Phytogenic; Buffers; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Methanol; Paclitaxel; Spectrophotometry, Ultraviolet; Taxoids

1995
Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures.
    Nature biotechnology, 1996, Volume: 14, Issue:9

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Biotechnology; Cells, Cultured; Cyclopentanes; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Species Specificity; Taxoids

1996
Measuring taxol production.
    Nature biotechnology, 1996, Volume: 14, Issue:13

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Biotechnology; Cells, Cultured; Cyclopentanes; Oxylipins; Paclitaxel; Plant Growth Regulators

1996
Cloning and functional expression of a cDNA encoding geranylgeranyl diphosphate synthase from Taxus canadensis and assessment of the role of this prenyltransferase in cells induced for taxol production.
    Archives of biochemistry and biophysics, 1998, Dec-01, Volume: 360, Issue:1

    Topics: Acetates; Alkyl and Aryl Transferases; Amino Acid Sequence; Base Sequence; Cells, Cultured; Cloning, Molecular; Cyclopentanes; Dimethylallyltranstransferase; DNA, Complementary; Enzyme Activation; Farnesyltranstransferase; Gene Expression; Genetic Complementation Test; Isomerases; Molecular Sequence Data; Mutagenesis; Oxylipins; Paclitaxel; Plant Proteins; Protein Prenylation; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Trees

1998
The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate.
    Biotechnology and bioengineering, 1999, Jan-05, Volume: 62, Issue:1

    Topics: Acetates; Alkaloids; Biotechnology; Cell Division; Cells, Cultured; Cyclopentanes; Kinetics; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Taxoids

1999
Use of gabapentin to treat taxane-induced myalgias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:1

    Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Cyclohexanecarboxylic Acids; Docetaxel; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Taxoids

1999
Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m.
    Journal of natural products, 1999, Volume: 62, Issue:10

    Topics: Acetates; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclopentanes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxylipins; Paclitaxel; Taxoids; Trees

1999
The configuration of methyl jasmonate affects paclitaxel and baccatin III production in Taxus cells.
    Phytochemistry, 2000, Volume: 54, Issue:1

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Cell Division; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyclopentanes; Oxylipins; Paclitaxel; Plants, Medicinal; Stereoisomerism; Taxoids; Taxus

2000
Noncovalent dimerization of paclitaxel in solution: evidence from electrospray ionization mass spectrometry.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:9

    Topics: Acetates; Acetonitriles; Antineoplastic Agents, Phytogenic; Dimerization; Drug Stability; Hydrogen-Ion Concentration; Paclitaxel; Sodium Acetate; Solutions; Solvents; Spectrometry, Mass, Electrospray Ionization

2002
Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata.
    Journal of biotechnology, 2003, Mar-06, Volume: 101, Issue:2

    Topics: Acetates; Alkaloids; Cell Survival; Culture Media; Culture Techniques; Cyclopentanes; Fosfomycin; Lovastatin; Oxylipins; Paclitaxel; Quality Control; Taxoids; Taxus

2003
Enhancement of taxol production and release in Taxus chinensis cell cultures by ultrasound, methyl jasmonate and in situ solvent extraction.
    Applied microbiology and biotechnology, 2003, Volume: 62, Issue:2-3

    Topics: Acetates; Cyclopentanes; Dibutyl Phthalate; Oxylipins; Paclitaxel; Plant Growth Regulators; Solvents; Taxus; Ultrasonics

2003
Use of gabapentin in the prevention of taxane-induced arthralgias and myalgias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Arthralgia; Cyclohexanecarboxylic Acids; Docetaxel; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle, Skeletal; Muscular Diseases; Paclitaxel; Retrospective Studies; Taxoids

2004
Selective inhibition of human cytochrome P4502C8 by montelukast.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:3

    Topics: Acetates; Amodiaquine; Anti-Asthmatic Agents; Aryl Hydrocarbon Hydroxylases; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Leukotriene Antagonists; Microsomes, Liver; Paclitaxel; Quinolines; Recombinant Proteins; Rosiglitazone; Sulfides; Thiazolidinediones

2005
Nitric oxide is involved in methyl jasmonate-induced defense responses and secondary metabolism activities of Taxus cells.
    Plant & cell physiology, 2005, Volume: 46, Issue:6

    Topics: Acetates; Cyclic N-Oxides; Cyclopentanes; Free Radical Scavengers; Hydrogen Peroxide; Imidazoles; Lipid Peroxidation; Lipoxygenase; Models, Biological; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitroprusside; Oxylipins; Paclitaxel; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Signal Transduction; Taxus

2005
Improved Taxol production by combination of inducing factors in suspension cell culture of Taxus baccata.
    Cell biology international, 2006, Volume: 30, Issue:3

    Topics: Acetates; Cell Culture Techniques; Cyclopentanes; Fungi; Oxylipins; Paclitaxel; Salicylic Acid; Taxus

2006
Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures.
    Biotechnology and bioengineering, 2006, Sep-05, Volume: 95, Issue:1

    Topics: Acetates; Cell Proliferation; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Oxylipins; Paclitaxel; Peptide Hormones; Peptides; Plant Growth Regulators; Plant Proteins; Taxus

2006
Poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as polymeric emulsifier for the preparation of biodegradable nanoparticles.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:7

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Drug Compounding; Emulsifying Agents; Etoposide; Freeze Drying; Kinetics; Lactates; Magnesium Chloride; Methylene Chloride; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polystyrenes; Polyvinyls; Solubility; Solvents; Technology, Pharmaceutical; Water

2007
Lipidomic analysis reveals differential defense responses of Taxus cuspidata cells to two elicitors, methyl jasmonate and cerium (Ce4+).
    Biochimica et biophysica acta, 2008, Volume: 1781, Issue:3

    Topics: Acetates; Apoptosis; Cell Membrane; Cerium; Chromatography, Liquid; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Lipid Metabolism; Models, Biological; Multivariate Analysis; Oxylipins; Paclitaxel; Phospholipase A2 Inhibitors; Phospholipase D; Phospholipases A2; Spectrometry, Mass, Electrospray Ionization; Taxus

2008
In vitro metabolism of 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid (licofelone, ML3000), an inhibitor of cyclooxygenase-1 and -2 and 5-lipoxygenase.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:5

    Topics: Acetates; Animals; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cyclopropanes; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Hepatocytes; Humans; Lipoxygenase Inhibitors; Macaca fascicularis; Mice; Mice, Inbred Strains; Microsomes; Paclitaxel; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfides

2008
Montelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavir.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:12

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line; Chemotherapy, Adjuvant; Cyclopropanes; Dogs; Drug Resistance, Neoplasm; Drug Resistance, Viral; Fluoresceins; HIV Infections; HIV Protease Inhibitors; Indoles; Leukotriene Antagonists; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Phenylcarbamates; Propionates; Quinolines; Saquinavir; Sulfides; Sulfonamides; Time Factors; Tosyl Compounds

2009
Taxus globosa S. cell lines: initiation, selection and characterization in terms of growth, and of baccatin III and paclitaxel production.
    Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2010, Volume: 34, Issue:1

    Topics: Acetates; Alkaloids; Cell Culture Techniques; Cell Line; Cell Proliferation; Culture Media; Cyclopentanes; Oxylipins; Paclitaxel; Taxoids; Taxus

2010
Flow cytometric methods to investigate culture heterogeneities for plant metabolic engineering.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 643

    Topics: Acetates; Cell Culture Techniques; Cell Nucleus; Cell Separation; Cell Size; Cyclopentanes; DNA, Plant; Flow Cytometry; Genetic Engineering; Oxylipins; Paclitaxel; Phenotype; Protoplasts; Taxus

2010
Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:9

    Topics: Acetates; Amodiaquine; Aryl Hydrocarbon Hydroxylases; Binding Sites; Carbamates; Cyclopropanes; Cytochrome P-450 CYP2C8; Drug Interactions; Humans; Microsomes, Liver; Paclitaxel; Piperidines; Quinolines; Rosiglitazone; Sensitivity and Specificity; Substrate Specificity; Sulfides; Thiazolidinediones

2011
Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in Taxus suspension cultures.
    Biotechnology journal, 2012, Volume: 7, Issue:3

    Topics: Acetates; Bridged-Ring Compounds; Cell Culture Techniques; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Plant Cells; Plant Proteins; Taxoids; Taxus

2012
Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells.
    BMC genomics, 2012, Apr-24, Volume: 13

    Topics: Acetates; Cell Line; Cyclopentanes; Expressed Sequence Tags; Gene Expression Regulation, Plant; Gene Library; Oxylipins; Paclitaxel; Plant Growth Regulators; Taxus

2012
Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis.
    Plant biology (Stuttgart, Germany), 2013, Volume: 15, Issue:1

    Topics: Acetates; Acetyltransferases; Amino Acid Sequence; Base Sequence; Cells, Cultured; Cyclopentanes; Gene Expression; Gene Expression Regulation, Plant; Gene Library; Molecular Sequence Data; Oxylipins; Paclitaxel; Plant Leaves; Plant Proteins; Promoter Regions, Genetic; RNA Interference; Sequence Analysis, DNA; Sequence Deletion; Taxoids; Taxus; Transcription Factors; Transcriptional Activation; Two-Hybrid System Techniques

2013
Transcriptional profile of Taxus chinensis cells in response to methyl jasmonate.
    BMC genomics, 2012, Jul-02, Volume: 13

    Topics: Acetates; Cells, Cultured; Cyclopentanes; DNA, Complementary; Gene Expression Profiling; Oxylipins; Paclitaxel; Plant Growth Regulators; Propanols; Signal Transduction; Taxoids; Taxus; Transcription, Genetic

2012
Deep sequencing reveals transcriptome re-programming of Taxus × media cells to the elicitation with methyl jasmonate.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Acetates; Cell Line; Cells, Cultured; Computational Biology; Cyclopentanes; Databases, Genetic; Ethylenes; Gene Expression Regulation, Plant; Genes, Plant; High-Throughput Nucleotide Sequencing; MicroRNAs; Molecular Sequence Annotation; Oxylipins; Paclitaxel; Plant Cells; Plant Growth Regulators; Reproducibility of Results; RNA, Messenger; Taxus; Terpenes; Transcriptome

2013
Metabolic engineering of Nicotiana benthamiana for the increased production of taxadiene.
    Plant cell reports, 2014, Volume: 33, Issue:6

    Topics: Acetates; Alkenes; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cyclopentanes; Diterpenes; Gene Silencing; Humans; Isomerases; Metabolic Engineering; Metabolic Networks and Pathways; Nicotiana; Oxylipins; Paclitaxel; Plant Growth Regulators; Polyisoprenyl Phosphates; Taxoids; Taxus

2014
Methyl jasmonate represses growth and affects cell cycle progression in cultured Taxus cells.
    Plant cell reports, 2014, Volume: 33, Issue:9

    Topics: Acetates; Apoptosis; Biomass; Cell Cycle; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Plant Growth Regulators; Plant Proteins; Taxus

2014
A new 2α,5α,10β,14β-tetraacetoxy-4(20),11-taxadiene (SIA) derivative overcomes paclitaxel resistance by inhibiting MAPK signaling and increasing paclitaxel accumulation in breast cancer cells.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Diterpenes; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; MAP Kinase Signaling System; Paclitaxel; Xenograft Model Antitumor Assays

2014
Development of a hazel cell culture-based paclitaxel and baccatin III production process on a benchtop scale.
    Journal of biotechnology, 2015, Feb-10, Volume: 195

    Topics: Acetates; Alkaloids; Amino Acids; Antineoplastic Agents; Biomass; Bioreactors; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Corylus; Cyclopentanes; Indenes; Oxylipins; Paclitaxel; Plant Growth Regulators; Taxoids

2015
Esters of the marine-derived triterpene sipholenol A reverse P-GP-mediated drug resistance.
    Marine drugs, 2015, Apr-14, Volume: 13, Issue:4

    Topics: Absorption, Physiological; Acetates; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Callyspongia; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Esterification; HEK293 Cells; Humans; Isonicotinic Acids; Molecular Conformation; Molecular Docking Simulation; Paclitaxel; Recombinant Proteins; Triterpenes

2015
Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer.
    Nature communications, 2015, Sep-16, Volume: 6

    Topics: Acetates; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Dexamethasone; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Glucocorticoids; Humans; Ligands; Paclitaxel; Receptors, Glucocorticoid; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Triple Negative Breast Neoplasms; Tyramine

2015
Regulation of bolting and identification of the α-tubulin gene family in Brassica rapa L. ssp pekinensis.
    Genetics and molecular research : GMR, 2016, Jan-29, Volume: 15, Issue:1

    Topics: Acetates; Arabidopsis; Base Sequence; Brassica rapa; Cyclopentanes; Exons; Flowers; Gene Expression Regulation, Developmental; Genome, Plant; Gibberellins; Introns; Microtubules; Molecular Sequence Data; Oxylipins; Paclitaxel; Plant Development; Plant Growth Regulators; Plant Proteins; Promoter Regions, Genetic; Protein Isoforms; Sequence Alignment; Tubulin

2016
Compound A attenuates toll-like receptor 4-mediated paclitaxel resistance in breast cancer and melanoma through suppression of IL-8.
    BMC cancer, 2018, 02-27, Volume: 18, Issue:1

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Interleukin-6; Interleukin-8; Melanoma; Paclitaxel; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment; Tyramine

2018
Novel resources of Taxol from endophytic and entomopathogenic fungi: Isolation, characterization and LC-Triple mass spectrometric quantification.
    Talanta, 2018, Dec-01, Volume: 190

    Topics: Acetates; Animals; Calibration; Chromatography, High Pressure Liquid; Cladosporium; Limit of Detection; Paclitaxel; Salicylic Acid; Sea Anemones; Tandem Mass Spectrometry

2018
The Ethyl Acetate Fraction of Marine Sponge Stylissa carteri Induces Breast Cancer Cell Death via Upregulation of Mcl-1S: an In vitro Study.
    Asian Pacific journal of cancer prevention : APJCP, 2022, May-01, Volume: 23, Issue:5

    Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Death; Cell Line, Tumor; Female; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Paclitaxel; Porifera; Up-Regulation

2022
Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus x media cell cultures.
    Phytochemistry, 2003, Volume: 62, Issue:6

    Topics: Acetates; Alkaloids; Cells, Cultured; Cyclopentanes; Molecular Structure; Oxidation-Reduction; Oxylipins; Taxus

2003
Methyl jasmonate induces changes mimicking anatomical defenses in diverse members of the Pinaceae.
    Tree physiology, 2003, Volume: 23, Issue:6

    Topics: Acetates; Cyclopentanes; Larix; Oxylipins; Picea; Pinaceae; Pinus; Plant Bark; Plant Growth Regulators; Plant Stems; Pseudotsuga; Taxus; Trees

2003
[Microbial transformation of sinenxan A, a rich constituent in callus cultures of Taxus].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:7

    Topics: Acetates; Biotransformation; Culture Techniques; Cunninghamella; Diterpenes; Mucor; Plants, Medicinal; Proteus vulgaris; Taxus

2003
Novel chemically synthesized hydroxyl-containing jasmonates as powerful inducing signals for plant secondary metabolism.
    Biotechnology and bioengineering, 2004, Jun-30, Volume: 86, Issue:7

    Topics: Acetates; Cell Line; Cyclopentanes; Esters; Glucosides; Hydrogen Peroxide; Molecular Structure; Oxylipins; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Quantitative Structure-Activity Relationship; Taxoids; Taxus

2004
Molecular cloning and characterization of the yew gene encoding squalene synthase from Taxus cuspidata.
    Journal of biochemistry and molecular biology, 2007, Sep-30, Volume: 40, Issue:5

    Topics: Acetates; Amino Acid Sequence; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; Cyclopentanes; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gibberellins; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Oxylipins; Plant Growth Regulators; Plant Proteins; Promoter Regions, Genetic; Protein Structure, Secondary; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Taxus

2007
High throughput sequencing technology reveals that the taxoid elicitor methyl jasmonate regulates microRNA expression in Chinese yew (Taxus chinensis).
    Gene, 2009, May-01, Volume: 436, Issue:1-2

    Topics: Acetates; Cell Line; Chromatography, High Pressure Liquid; Cyclopentanes; Gene Expression Regulation, Plant; MicroRNAs; Oxylipins; Plant Growth Regulators; RNA, Plant; Sequence Analysis, RNA; Taxoids; Taxus

2009
Isolation and characterization of a novel cDNA encoding methyl jasmonate-responsive transcription factor TcAP2 from Taxus cuspidata.
    Biotechnology letters, 2009, Volume: 31, Issue:11

    Topics: Acetates; Amino Acid Sequence; Base Sequence; Cyclopentanes; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Molecular Sequence Data; Organ Specificity; Oxylipins; Phylogeny; Plant Proteins; Protein Binding; Protein Transport; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, Protein; Stress, Physiological; Subcellular Fractions; Taxus; Transcription Factors

2009
Enhancement of taxane production in hairy root culture of Taxus x media var. Hicksii.
    Journal of plant physiology, 2009, Nov-15, Volume: 166, Issue:17

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Benzoates; Biomass; Culture Media; Cyclopentanes; Oxylipins; Phenylalanine; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Taxoids; Taxus; Tissue Culture Techniques

2009
[Enhanced production of taxuyunnanine c in cell suspension cultures of Taxus chinensis by methyl jasmonate elicitation and in situ absorption].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2010, Volume: 26, Issue:2

    Topics: Absorption; Acetates; Acrylic Resins; Cell Culture Techniques; Cyclopentanes; Oxylipins; Polystyrenes; Taxoids; Taxus

2010
Synthesis and structure-activity relationships of sinenxan A derivatives as multidrug resistance reversal agents.
    Bioorganic & medicinal chemistry letters, 2010, Sep-15, Volume: 20, Issue:18

    Topics: Acetates; Calcium Channel Blockers; Diterpenes; Drug Resistance, Multiple; Humans; Neoplasms; Structure-Activity Relationship; Taxus; Tumor Cells, Cultured; Verapamil

2010
Coronatine, a more powerful elicitor for inducing taxane biosynthesis in Taxus media cell cultures than methyl jasmonate.
    Journal of plant physiology, 2013, Jan-15, Volume: 170, Issue:2

    Topics: Acetates; Amino Acids; Cells, Cultured; Cyclopentanes; Gene Expression Regulation, Plant; Genes, Plant; Indenes; Oxylipins; Plant Growth Regulators; Taxoids; Taxus

2013
Isolation of alpha-glucosidase inhibitors produced by an endophytic fungus, Colletotrichum sp. TSC13 from Taxus sumatrana.
    Pakistan journal of biological sciences : PJBS, 2012, Jul-15, Volume: 15, Issue:14

    Topics: Acetates; Chloroform; Colletotrichum; Enzyme Inhibitors; Esters; Fatty Acids; Fatty Acids, Unsaturated; Fermentation; Glycoside Hydrolase Inhibitors; Hexanes; Methanol; Taxus

2012
Synergistic effect of cyclodextrins and methyl jasmonate on taxane production in Taxus x media cell cultures.
    Plant biotechnology journal, 2014, Volume: 12, Issue:8

    Topics: Acetates; Biosynthetic Pathways; Bridged-Ring Compounds; Cells, Cultured; Cyclodextrins; Cyclopentanes; Drug Synergism; Gene Expression Regulation, Plant; Oxylipins; Plant Proteins; Taxoids; Taxus

2014
Identification and characterization of MYC transcription factors in Taxus sp.
    Gene, 2018, Oct-30, Volume: 675

    Topics: Acetates; Cloning, Molecular; Cyclopentanes; Gene Expression Regulation, Plant; Genes, myc; Genes, Plant; Metabolic Networks and Pathways; Oxylipins; Phylogeny; Taxus; Transcription Factors; Transcriptome

2018