Page last updated: 2024-08-23

paclitaxel and parthenolide

paclitaxel has been researched along with parthenolide in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (43.75)29.6817
2010's5 (31.25)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Goto, M; Lee, KH; Li, Y; Morris-Natschke, SL; Su, J; Yao, ZJ; Zhao, QS; Zhao, Y1
Bhat-Nakshatri, P; Boswell, SH; Gelfanov, V; Goulet, RJ; Nakshatri, H; Newton, TR; Nozaki, S; Patel, NM; Rice, S; Shortle, NH; Sledge, GW1
Bocca, C; Bozzo, F; Gabriel, L; Miglietta, A1
Ausseil, F; Barette, C; Cintrat, JC; David, B; Fonrose, X; Lafanechère, L; Massiot, G; Masson, V; Pouny, I; Rousseau, B; Soleilhac, E1
Bai, J; Gu, P; Margolick, JB; Zhang, H; Zhang, Y; Zhou, J1
Guo, C; Guo, Z; Jin, X; Qiu, L; Zhang, D1
Gao, ZW; Guo, CB; Zhang, DL1
Gill, KK; Kaddoumi, A; Nazzal, S1
Andreadaki, A; Diekmann, H; Fischer, D; Gobrecht, P; Heskamp, A; Leibinger, M1
Chai, Z; Li, J; Lu, L; Lu, W; Mao, J; Ran, D; Wu, S; Xie, C; Zhan, C; Zhang, Y; Zhou, J1
Jin, X; Lu, X; Lv, H; Zhang, Z1
Bayram, C; Budak, H; Hacımüftüoğlu, A; Özkaraca, M; Sezen, S; Toraman, E1
Du, G; Jia, X; Li, Y; Liu, Q; Wang, S; Zeng, B; Zhang, C1

Other Studies

16 other study(ies) available for paclitaxel and parthenolide

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activation.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; NF-kappa B; Paclitaxel; Polymerization; Sesquiterpenes; Structure-Activity Relationship; Taxoids; Tubulin; Tubulin Modulators

2013
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide.
    Oncogene, 2000, Aug-24, Volume: 19, Issue:36

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Breast Neoplasms; Caenorhabditis elegans Proteins; DNA; DNA-Binding Proteins; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Inhibitor of Apoptosis Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Plants, Medicinal; Protein Binding; Proteins; Repressor Proteins; Sesquiterpenes; Superoxide Dismutase; TNF Receptor-Associated Factor 1; Tumor Cells, Cultured

2000
Microtubule-interfering activity of parthenolide.
    Chemico-biological interactions, 2004, Oct-15, Volume: 149, Issue:2-3

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Colchicine; Cytoskeleton; Dose-Response Relationship, Drug; Female; Humans; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Paclitaxel; Plant Extracts; Sesquiterpenes; Tanacetum parthenium; Tubulin

2004
Parthenolide inhibits tubulin carboxypeptidase activity.
    Cancer research, 2007, Apr-01, Volume: 67, Issue:7

    Topics: Carboxypeptidases; Drug Interactions; HeLa Cells; Humans; NF-kappa B; Paclitaxel; Sesquiterpenes; Structure-Activity Relationship; Tubulin

2007
NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.
    Breast cancer research and treatment, 2008, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Female; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Paclitaxel; Pyrrolidines; Sesquiterpenes; Spheroids, Cellular; Thiocarbamates; Time Factors; Xenograft Model Antitumor Assays

2008
Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:7

    Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Synergism; Histocytochemistry; I-kappa B Kinase; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mitochondrial Membranes; NF-kappa B; Paclitaxel; Sesquiterpenes; Xenograft Model Antitumor Assays

2009
Paclitaxel efficacy is increased by parthenolide via nuclear factor-kappaB pathways in in vitro and in vivo human non-small cell lung cancer models.
    Current cancer drug targets, 2010, Volume: 10, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Nucleus; Cell Survival; Drug Synergism; Humans; I-kappa B Proteins; Lung Neoplasms; Mice; Mice, Nude; NF-kappa B; Paclitaxel; Phosphorylation; Protein Transport; Random Allocation; Sesquiterpenes; Survival Analysis; Xenograft Model Antitumor Assays

2010
Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, May-12, Volume: 46, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Micelles; Paclitaxel; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Sesquiterpenes; Vitamin E

2012
Promotion of Functional Nerve Regeneration by Inhibition of Microtubule Detyrosination.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Apr-06, Volume: 36, Issue:14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Axons; Dose-Response Relationship, Drug; Gene Knock-In Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Mice, Inbred C57BL; Microtubules; Nerve Regeneration; Nocodazole; Paclitaxel; Peripheral Nerves; Phosphorylation; Sciatic Nerve; Sesquiterpenes; Tyrosine

2016
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
    Theranostics, 2020, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticulum Chaperone BiP; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Rats, Sprague-Dawley; Sesquiterpenes; Temozolomide

2020
Indocyanine Green-Parthenolide Thermosensitive Liposome Combination Treatment for Triple-Negative Breast Cancer.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Delivery Systems; Endocytosis; Female; Humans; Hydrodynamics; Indocyanine Green; Liposomes; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Photosensitizing Agents; Reactive Oxygen Species; Sesquiterpenes; Temperature; Tissue Distribution; Treatment Outcome; Triple Negative Breast Neoplasms; Tumor Burden

2020
Parthenolide as a potential analgesic in the treatment of paclitaxel-induced neuropathic pain: the rat modeling.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:12

    Topics: Analgesics; Animals; Neuralgia; Paclitaxel; Rats; Sesquiterpenes

2023
Synthesis, cytotoxicity, and in vivo antitumor activity study of parthenolide semicarbazones and thiosemicarbazones.
    Bioorganic & medicinal chemistry, 2020, 07-01, Volume: 28, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carbamates; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Neoplasms, Experimental; NF-kappa B; Semicarbazones; Sesquiterpenes; Structure-Activity Relationship; Thiosemicarbazones

2020