Page last updated: 2024-08-23

paclitaxel and monastrol

paclitaxel has been researched along with monastrol in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (70.59)29.6817
2010's4 (23.53)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bougeret, C; Guillou, C; Kozielski, F; Labrière, C; Talapatra, SK; Thoret, S1
Kimura, KI; Koshino, H; Kurisawa, N; Onodera, T; Toda, T; Yukawa, M1
Cole, RW; Hauf, S; Heckel, A; LaTerra, S; Peters, JM; Rieder, CL; Schnapp, G; van Meel, J; Walter, R; Zimmer, C1
Agami, R; Brummelkamp, T; Kauw, J; Klompmaker, R; Kops, G; Lens, SM; Medema, RH; Wolthuis, RM1
Baas, PW; Brooks, AD; Haque, SA; Hasaka, TP; Lobanov, PV1
Avunie-Masala, R; Elkabets, M; Fich, A; Gheber, L; Leizerman, I1
Haefeli, WE; Lindenmaier, H; Peters, T; Weiss, J1
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V1
Kropf, DL; Peters, NT1
Chin, GM; Herbst, R1
Georgi, A; Hamprecht, F; Kirchner, M; Kirschner, MW; Parker, K; Springer, M; Steen, H; Steen, JA1
Conklin, DS; Hergert, P; Khodjakov, A; Kourtidis, A; Loncarek, J; O'Connell, CB1
Mattaj, IW; Platani, M; Posch, M; Santarella-Mellwig, R; Swedlow, JR; Walczak, R1
Baas, PW; Lin, S; Nadar, VC1
Chiba, S; Ikeda, M; Kanno, S; Mizuno, K; Nagai, T1
Bolte, S; Buffin, E; Cladière, D; El Yakoubi, W; Leontiou, I; Vallot, A; Wassmann, K1

Other Studies

17 other study(ies) available for paclitaxel and monastrol

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.
    Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4

    Topics: Acrylonitrile; Animals; Antimitotic Agents; Brain Chemistry; Cell Line, Tumor; Cytokinesis; Drug Design; Epithelial Cells; Gene Expression; Humans; Indoles; Kinesins; Microtubules; Sheep; Structure-Activity Relationship

2016
Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Cell Line, Tumor; Centrosome; Diterpenes; Dose-Response Relationship, Drug; Humans; Kinesins; Mitosis; Molecular Structure; Schizosaccharomyces; Spindle Apparatus; Structure-Activity Relationship

2020
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
    The Journal of cell biology, 2003, Apr-28, Volume: 161, Issue:2

    Topics: Anaphase; Aneugens; Animals; Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; Chromosome Segregation; Endopeptidases; Eukaryotic Cells; Genes, cdc; HeLa Cells; Humans; Indoles; Kinetochores; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phenotype; Polyploidy; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; RNA, Small Interfering; Separase; Spindle Apparatus; Sulfonamides; Thiones

2003
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension.
    The EMBO journal, 2003, Jun-16, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aurora Kinase B; Aurora Kinases; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line; Chromosomes, Human; Chromosomes, Mammalian; Cysteine Proteinase Inhibitors; Genes, Reporter; Humans; Inhibitor of Apoptosis Proteins; Mad2 Proteins; Mice; Microtubule-Associated Proteins; Mitosis; Neoplasm Proteins; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; Recombinant Fusion Proteins; Repressor Proteins; Signal Transduction; Spectrin; Spindle Apparatus; Stress, Mechanical; Survivin; Thiones

2003
Monastrol, a prototype anti-cancer drug that inhibits a mitotic kinesin, induces rapid bursts of axonal outgrowth from cultured postmitotic neurons.
    Cell motility and the cytoskeleton, 2004, Volume: 58, Issue:1

    Topics: Animals; Antineoplastic Agents; Axons; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Kinesins; Mitosis; Neurons; Neurons, Afferent; Paclitaxel; Pyrimidines; Rats; Thiones

2004
Differential effects of monastrol in two human cell lines.
    Cellular and molecular life sciences : CMLS, 2004, Volume: 61, Issue:16

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Colonic Neoplasms; G2 Phase; HT29 Cells; Humans; Kinesins; Microtubules; Mitosis; Paclitaxel; Pyrimidines; Stomach Neoplasms; Thiones

2004
Interaction of the mitotic kinesin Eg5 inhibitor monastrol with P-glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 372, Issue:4

    Topics: Animals; Antimitotic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Fluoresceins; Gene Expression Regulation; Humans; Kinesins; LLC-PK1 Cells; Mice; Microscopy, Confocal; Paclitaxel; Pyrimidines; RNA, Messenger; Swine; Thiones; Tubulin

2006
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine

2007
Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.
    BMC plant biology, 2006, Aug-31, Volume: 6

    Topics: Cell Polarity; Cysteine; Cytokinesis; Dinitrobenzenes; Kinesins; Microtubules; Mitosis; Molecular Motor Proteins; Paclitaxel; Phaeophyceae; Pyrimidines; Spindle Apparatus; Sulfanilamides; Thiones; Zygote

2006
Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:10

    Topics: Calcium-Binding Proteins; Caspases; Cell Cycle Proteins; DNA; Enzyme Activation; HeLa Cells; Humans; Kinesins; Mad2 Proteins; Mitosis; Paclitaxel; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; Repressor Proteins; RNA, Small Interfering; Spindle Apparatus; Thiones

2006
Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-22, Volume: 105, Issue:16

    Topics: Anaphase-Promoting Complex-Cyclosome; Antimitotic Agents; HeLa Cells; Humans; Mass Spectrometry; Nocodazole; Paclitaxel; Phosphorylation; Prometaphase; Protein Subunits; Proteomics; Pyrimidines; Spindle Apparatus; Thiones; Ubiquitin-Protein Ligase Complexes; Vincristine

2008
The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.
    The Journal of cell biology, 2008, Oct-06, Volume: 183, Issue:1

    Topics: Anaphase; Autoantigens; Calcium-Binding Proteins; Cell Cycle Proteins; Centromere Protein A; Chromatin; Chromosomal Proteins, Non-Histone; DNA Replication; Enzyme Inhibitors; Genome, Human; HeLa Cells; Humans; Hydroxyurea; Indoles; Kinetics; Kinetochores; Mad2 Proteins; Metaphase; Microscopy, Electron; Microtubules; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pyrimidines; Repressor Proteins; Spindle Apparatus; Sulfonamides; Thiones

2008
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex.
    Molecular biology of the cell, 2009, Volume: 20, Issue:24

    Topics: Anaphase; Aurora Kinase B; Aurora Kinases; Chromosome Segregation; Chromosomes, Human; Cytokinesis; HeLa Cells; Humans; Kinesins; Kinetochores; Mitosis; Nocodazole; Nuclear Pore Complex Proteins; Nuclear Proteins; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pyrimidines; Spindle Apparatus; Substrate Specificity; Thiones

2009
Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-25, Volume: 32, Issue:17

    Topics: Animals; Cells, Cultured; Embryo, Nonmammalian; Female; Ganglia, Sympathetic; Growth Cones; Kinesins; Laser Capture Microdissection; Luminescent Proteins; Male; Microscopy, Confocal; Microtubule-Associated Proteins; Microtubules; Mutation; Neurons; Paclitaxel; Pregnancy; Pyrimidines; Radiation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Thiones; Time Factors; Tubulin Modulators; Xenopus

2012
Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.
    Journal of cell science, 2013, Oct-01, Volume: 126, Issue:Pt 19

    Topics: Acetylation; Animals; Cell Cycle Proteins; Gene Knockdown Techniques; HEK293 Cells; HeLa Cells; Humans; Mice; Microtubule-Associated Proteins; Microtubules; Paclitaxel; Pyrimidines; Sirtuin 2; Spindle Apparatus; Thiones; Transfection

2013
Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes.
    Current biology : CB, 2018, 01-08, Volume: 28, Issue:1

    Topics: Animals; Cell Division; Cysteine; Female; Kinesins; Kinetochores; M Phase Cell Cycle Checkpoints; Meiosis; Mice; Oocytes; Paclitaxel; Pyrimidines; Thiones; Tubulin Modulators

2018