paclitaxel has been researched along with idn 5109 in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 14 (73.68) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Battaglia, A; Bernacki, RJ; Bertucci, C; Bombardelli, E; Cimitan, S; Ferlini, C; Fontana, G; Guerrini, A; Riva, A | 1 |
| Appendino, G; Ballini, R; Barboni, L; Bombardelli, E; Fontana, G; Giarlo, G | 1 |
| Jing, YR; Li, WL; Wang, YF; Zhao, LX; Zhou, W | 1 |
| Bombardelli, E; Colombo, T; D'Incalci, M; Frapolli, R; Morazzoni, P; Riva, A; Zucchetti, M | 1 |
| Bombardelli, E; Colombo, T; D'Incalci, M; Donati, MB; Giavazzi, R; Monardo, C; Morazzoni, P; Nicoletti, MI; Riva, A; Rossi, C; Stura, S; Zucchetti, M | 1 |
| Bombardelli, E; Colombo, T; D'Incalci, M; Monestiroli, S; Morazzoni, P; Polizzi, D; Pratesi, G; Riva, A; Tortoreto, M; Zucchetti, M; Zunino, F | 1 |
| Bombardelli, E; Bonanno, G; Distefano, M; Ferlini, C; Mancuso, S; Ojima, I; Pierelli, L; Riva, A; Scambia, G | 1 |
| Cassinelli, G; Lanzi, C; Perego, P; Polizzi, D; Pratesi, G; Supino, R; Zunino, F | 1 |
| Bissery, MC | 1 |
| Bernacki, RJ; Cabral, F; Greco, WR; Kanter, P; Kee, K; Ojima, I; Pera, P; Sharma, A; Veith, J; Vredenburg, MR | 1 |
| Colombo, T; D'Incalci, M; Fruscio, R; Minoia, C; Sottani, C; Zucchetti, M | 1 |
| Bombardelli, E; D'Incalci, M; Laccabue, D; Perego, P; Pratesi, G; Scanziani, E; Tortoreto, M; Veneroni, S; Zaffaroni, M; Zucchetti, M; Zunino, F | 1 |
| Distefano, M; Ferlini, C; Jordan, MA; Ojima, I; Rosas, F; Scambia, G; Wilson, L | 1 |
| Lavelle, F | 1 |
| Bombardelli, E; Cassinelli, G; Cuccuru, G; Laccabue, D; Lanzi, C; Pratesi, G; Supino, R; Zuco, V; Zunino, F | 1 |
| Frangioni, JV; Maison, W | 1 |
| Ishiguro, Y; Kawakami, M; Matsuda, H; Nishimura, G; Sano, D; Tsukuda, M | 1 |
| Cappelletti, G; Cartelli, D; Contini, A; Fontana, G; Gelmi, ML | 1 |
| Farhan, H; Guo, W; Liu, D; Liu, Y; Momen Ali, SA; Ojima, I; Rong, D; Taouil, A; Wang, C; Wang, H; Wang, Y; Wei, Y; Yang, S; Zhang, M; Zhang, X | 1 |
2 review(s) available for paclitaxel and idn 5109
| Article | Year |
|---|---|
Preclinical evaluation of new taxoids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Docetaxel; Neoplasms, Experimental; Paclitaxel; Taxoids | 2001 |
[New taxanes and epothilone derivatives in clinical trials].
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Clinical Trials, Phase I as Topic; Drug Screening Assays, Antitumor; Humans; Mice; Neutropenia; Paclitaxel; Taxoids | 2002 |
17 other study(ies) available for paclitaxel and idn 5109
| Article | Year |
|---|---|
Synthesis and biological evaluation of 2'-methyl taxoids derived from baccatin III and 14beta-OH-baccatin III 1,14-carbonate.
Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Structure-Activity Relationship; Taxoids | 2003 |
Synthesis and biological evaluation of methoxylated analogs of the newer generation taxoids IDN5109 and IDN5390.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Cell Line, Tumor; Humans; Taxoids | 2005 |
The synthesis of novel taxoids for oral administration.
Topics: Administration, Oral; Animals; Dogs; Humans; Paclitaxel; Taxoids | 2014 |
High-performance liquid chromatographic assay for the determination of the novel taxane derivative IDN5109 in mouse plasma.
Topics: Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drug Stability; Female; Freezing; Kinetics; Mice; Paclitaxel; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Taxoids | 1999 |
IDN5109, a taxane with oral bioavailability and potent antitumor activity.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Taxoids | 2000 |
Oral efficacy and bioavailability of a novel taxane.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Taxoids; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured | 2000 |
Cytotoxic effects toward human hematopoietic progenitor cells and tumor cell lines of paclitaxel, docetaxel, and newly developed analogues IDN5109, IDN5111, and IDN5127.
Topics: Antigens, CD34; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Cycle; Cell Division; Docetaxel; Drug Resistance, Multiple; Flow Cytometry; Hematopoietic Stem Cells; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Paclitaxel; Taxoids; Time Factors; Tumor Cells, Cultured | 1999 |
A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bridged-Ring Compounds; Cell Cycle; DNA, Neoplasm; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Taxoids; Tubulin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Effects of orally active taxanes on P-glycoprotein modulation and colon and breast carcinoma drug resistance.
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Bridged-Ring Compounds; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Fluorescence; Humans; Male; Paclitaxel; Taxoids; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured | 2001 |
High-performance liquid chromatography/tandem mass spectrometry for the quantitative analysis of a novel taxane derivative (BAY59-8862) in biological samples and characterisation of its metabolic profile in rat bile samples.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bile; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Liver; Mass Spectrometry; Mice; Mice, Nude; Molecular Conformation; Molecular Structure; Paclitaxel; Rats; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Taxoids | 2001 |
A novel taxane active against an orthotopically growing human glioma xenograft.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Neoplasms; Bridged-Ring Compounds; Glioma; Humans; Indoles; Infusions, Intravenous; Mice; Mice, Nude; Paclitaxel; Taxoids; Transplantation, Heterologous | 2001 |
Effects of novel taxanes SB-T-1213 and IDN5109 on tubulin polymerization and mitosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bridged-Ring Compounds; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microscopy, Electron; Microtubules; Mitosis; Paclitaxel; Taxoids; Tubulin | 2002 |
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Topics: Antineoplastic Agents; bcl-X Protein; Blotting, Western; Bridged-Ring Compounds; CDC2 Protein Kinase; Cell Cycle; Cell Death; Cell Division; Cell Nucleus; Cell Separation; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Growth Factors; Fibroblast Growth Factor 2; Flow Cytometry; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Maturation-Promoting Factor; Mitosis; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Subcellular Fractions; Taxoids; Time Factors; Tubulin; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Improved chemical strategies for the targeted therapy of cancer.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bridged-Ring Compounds; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Ligands; Mandelic Acids; Neoplasms; Oligopeptides; Paclitaxel; Taxoids | 2003 |
Antitumor effects of IDN5109 on head and neck squamous cell carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Head and Neck Neoplasms; Humans; Neovascularization, Pathologic; Paclitaxel; Taxoids | 2006 |
Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction.
Topics: Bridged-Ring Compounds; Cell Line, Tumor; Computational Biology; Humans; Kinetics; MCF-7 Cells; Microtubules; Models, Molecular; Molecular Dynamics Simulation; Paclitaxel; Protein Binding; Protein Conformation; Protein Multimerization; Taxoids; Tubulin | 2012 |
A novel taxane, difluorovinyl-ortataxel, effectively overcomes paclitaxel-resistance in breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Bridged-Ring Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Female; G2 Phase Cell Cycle Checkpoints; Humans; Mice; Mice, Inbred BALB C; Paclitaxel; Taxoids; Tubulin | 2020 |