Page last updated: 2024-08-23

paclitaxel and cyclopentane

paclitaxel has been researched along with cyclopentane in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (18.03)18.2507
2000's26 (42.62)29.6817
2010's23 (37.70)24.3611
2020's1 (1.64)2.80

Authors

AuthorsStudies
McGuinness, MP; Orth, JM1
Benjamins, JA; Nedelkoska, L1
Malhotra, V; Veit, B; Yucel, JK1
Tritton, TR; Vichi, PJ1
Weber, G; Yeh, YA1
Hara, Y; Higashi, Y; Tabata, H; Yukimune, Y1
Schuler, ML1
Raymond, MN; Robin, P; Rossignol, B1
Croteau, R; Hefner, J; Ketchum, RE1
Croteau, RB; Gibson, DM; Ketchum, RE; Shuler, ML1
Begley, T; Gibson, DM; Ketchum, RE; Shuler, ML; Tandon, M1
Hara, Y; Nomura, E; Seto, H; Yoshida, S; Yukimune, Y1
Haigh, JR; Linden, JC; Mirjalili, N; Phisaphalong, M1
Bonfill, M; Cusidó, RM; Morales, C; Palazón, J; Piñol, MT1
Lin, L; Wu, J1
Ge, X; Wu, J1
Engelberth, J1
Wang, JW; Wu, JY1
Dadpour, MR; Ghasempour, A; Khosroushahi, AY; Khosrowshahli, M; Naghdibadi, H; Omidi, Y; Valizadeh, M1
Gibson, DM; Kim, BJ; Shuler, ML1
Tabata, H1
Lu, SH; Yang, S; Yuan, YJ1
Itoh, K; Muranaka, T; Tachinbana, S1
Barradas-Dermitz, DM; Hayward-Jones, PM; Mata-Rosas, M; Palmeros-Sánchez, B; Platas-Barradas, OB; Velásquez-Toledo, RF1
Gaurav, V; Kolewe, ME; Roberts, SC1
Kolewe, ME; Normanly, J; Patil, RA; Roberts, SC; Walker, EL1
Boutaoui, N; Lenka, SK; Normanly, J; Paulose, B; Roberts, SC; Vongpaseuth, K; Walker, EL1
Fu, C; Li, S; Yu, L; Zhang, M; Zhang, P1
Dong, YS; Fu, CH; Guo, AY; Li, ST; Yu, LJ; Zhang, M; Zhang, P; Zhao, CF1
Bonfill, M; Cusidó, RM; Hernández-Vázquez, L; Moyano, E; Onrubia, M; Palazon, J; Ramirez, K1
Liu, H; Qiu, D; Sun, G; Tang, Q; Wen, JF; Wilson, IW; Wu, J; Xie, F; Yang, Y1
Baek, KH; Hasan, MM; Jeon, JH; Kim, HS; Kim, SH; Moon, B; Shim, SH; Song, JY1
Lenka, SK; Normanly, J; Patil, RA; Roberts, SC; Walker, EL1
Bonfill, M; Cusido, RM; Eibl, R; Gallego, A; Imseng, N; Moyano, E; Palazon, J1
Altabella, T; Cusido, RM; Goossens, A; Moyano, E; Notredame, C; Onrubia, M; Osuna, L; Palazon, J; Ramírez-Estrada, K; Vanden Bossche, R1
Chen, Q; Fu, C; Li, S; Nie, L; Xu, X; Yu, L; Zhang, M1
Fang, ZY; Guo, MH; Jin, D; Xu, C; Zhang, L; Zhang, YW1
Guo, H; Hong, X; Li, S; Li, W; Wei, W; Wei, Z; Xie, M; Zhang, S1
Bauer, TM; Faessel, H; Faller, DV; Harvey, RD; Lockhart, AC; Nemunaitis, J; Sedarati, F; Venkatakrishnan, K; Zhou, X1
Chen, J; Cui, Y; Guo, Z; Mao, R1
Chen, L; Huang, P; Wang, Y; Wu, L; Yang, L; Yao, R; Yu, H; Zhang, M1
Baebler, S; Camloh, M; Kovac, M; Ravnikar, M; Zel, J1
Croteau, RB; Ketchum, RE; Kim, YS; Qiu, D; Rithner, CD; Williams, RM1
Christiansen, E; Franceschi, VR; Hudgins, JW1
Qian, X; Qian, ZG; Tian, WH; Xu, Y; Zhao, ZJ; Zhong, JJ1
Qian, X; Qian, ZG; Xu, Y; Zhao, ZJ; Zhong, JJ4
Qian, X; Qian, Z; Tian, W; Xu, Y; Zhao, Z; Zhong, JJ1
Hu, F; Huang, J; Qian, X; Xu, Y; Zhong, JJ1
Cao, Y; Han, X; Hou, R; Huang, Z; Jiang, K; Liao, Z; Pi, Y; Sun, X; Tang, K; Wang, Q1
Li, F; Liu, M; Pan, X; Qiu, D; Teng, W; Wilson, IW; Zhang, B1
Dai, D; Dai, Y; Jin, Y; Kong, L; Li, W; Qin, Q; Tang, K; Zha, X1
Furmanowa, M; Kokoszka, A; Pietrosiuk, A; Syklowska-Baranek, K1
Gao, M; Yu, X; Zhang, W1
Fan, S; Gao, M; Li, X; Ruan, C; Zhang, W1
Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J1
Bonfill, M; Cusidó, RM; Moyano, E; Onrubia, M; Palazón, J; Pedreño, MA; Sabater-Jara, AB1
Chen, Y; Fu, C; Jin, X; Nie, L; Yu, L; Zhang, M1
Deyou, Q; Duanfen, C; Hongwei, L; Kaikai, Z; Liying, Y; Qiang, L; Xing, L; Yanfang, Y; Ying, W1

Reviews

3 review(s) available for paclitaxel and cyclopentane

ArticleYear
Gas concentration effects on secondary metabolite production by plant cell cultures.
    Advances in biochemical engineering/biotechnology, 2001, Volume: 72

    Topics: Acetates; Antimalarials; Antineoplastic Agents, Phytogenic; Artemisinins; Carbon Dioxide; Cell Culture Techniques; Cyclopentanes; Drugs, Chinese Herbal; Ethylenes; Humans; Molecular Structure; Oxygen; Oxylipins; Paclitaxel; Plant Cells; Plant Extracts; Plant Growth Regulators; Plants; Sesquiterpenes

2001
Production of paclitaxel and the related taxanes by cell suspension cultures of Taxus species.
    Current drug targets, 2006, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Cyclopentanes; Humans; Oxylipins; Paclitaxel; Taxus

2006
Bioprocessing of plant in vitro systems for the mass production of pharmaceutically important metabolites: paclitaxel and its derivatives.
    Current medicinal chemistry, 2013, Volume: 20, Issue:7

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Biotechnology; Cyclopentanes; Metabolic Engineering; Microtubules; Oxylipins; Paclitaxel; Plant Cells; Taxoids; Taxus

2013

Trials

1 trial(s) available for paclitaxel and cyclopentane

ArticleYear
Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Cyclopentanes; Cytochrome P-450 CYP3A Inhibitors; Docetaxel; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Humans; Itraconazole; Male; Middle Aged; Neoplasms; Paclitaxel; Pyrimidines

2019

Other Studies

57 other study(ies) available for paclitaxel and cyclopentane

ArticleYear
Gonocytes of male rats resume migratory activity postnatally.
    European journal of cell biology, 1992, Volume: 59, Issue:1

    Topics: Animals; Brefeldin A; Cell Movement; Cyclopentanes; Fluorescent Dyes; Germ Cells; Golgi Apparatus; Male; Monensin; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Testis

1992
Maintenance of membrane sheets by cultured oligodendrocytes requires continuous microtubule turnover and Golgi transport.
    Neurochemical research, 1994, Volume: 19, Issue:5

    Topics: Animals; Biological Transport; Biopolymers; Brefeldin A; Cells, Cultured; Cyclopentanes; Golgi Apparatus; Membranes; Mice; Microtubules; Oligodendroglia; Paclitaxel; Tubulin

1994
Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks.
    The Journal of cell biology, 1993, Volume: 122, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Cell Line; Cyclopentanes; Cytoplasm; Golgi Apparatus; Intracellular Membranes; Microscopy, Electron; Microtubules; Paclitaxel; Quinones; Rats; Temperature

1993
Protection from adriamycin cytotoxicity in L1210 cells by brefeldin A.
    Cancer research, 1993, Nov-01, Volume: 53, Issue:21

    Topics: Amsacrine; Animals; Biological Transport; Brefeldin A; Cell Survival; Cyclopentanes; DNA Damage; DNA Repair; Doxorubicin; Drug Synergism; Endoplasmic Reticulum; Etoposide; Golgi Apparatus; Kinetics; Leukemia L1210; Mice; Microtubules; Nocodazole; Paclitaxel; Temperature; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Growth inhibitory action of brefeldin A with taxol and tiazofurin in human breast carcinoma cells.
    Cancer biochemistry biophysics, 1995, Volume: 15, Issue:1

    Topics: Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Brefeldin A; Cell Division; Cyclopentanes; Drug Synergism; Humans; Macrolides; Paclitaxel; Ribavirin; Tumor Cells, Cultured

1995
Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures.
    Nature biotechnology, 1996, Volume: 14, Issue:9

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Biotechnology; Cells, Cultured; Cyclopentanes; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Species Specificity; Taxoids

1996
Measuring taxol production.
    Nature biotechnology, 1996, Volume: 14, Issue:13

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Biotechnology; Cells, Cultured; Cyclopentanes; Oxylipins; Paclitaxel; Plant Growth Regulators

1996
Microtubules and intracellular traffic of secretory proteins in rat extraorbital lacrimal glands.
    Advances in experimental medicine and biology, 1998, Volume: 438

    Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Carbon Radioisotopes; Cyclopentanes; Docetaxel; Eye Proteins; Galactose; Glycoproteins; Golgi Apparatus; In Vitro Techniques; Kinetics; Lacrimal Apparatus; Leucine; Macrolides; Male; Microtubules; Nocodazole; Paclitaxel; Rats; Rats, Sprague-Dawley; Taxoids; Time Factors; Tritium

1998
Cloning and functional expression of a cDNA encoding geranylgeranyl diphosphate synthase from Taxus canadensis and assessment of the role of this prenyltransferase in cells induced for taxol production.
    Archives of biochemistry and biophysics, 1998, Dec-01, Volume: 360, Issue:1

    Topics: Acetates; Alkyl and Aryl Transferases; Amino Acid Sequence; Base Sequence; Cells, Cultured; Cloning, Molecular; Cyclopentanes; Dimethylallyltranstransferase; DNA, Complementary; Enzyme Activation; Farnesyltranstransferase; Gene Expression; Genetic Complementation Test; Isomerases; Molecular Sequence Data; Mutagenesis; Oxylipins; Paclitaxel; Plant Proteins; Protein Prenylation; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Trees

1998
The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate.
    Biotechnology and bioengineering, 1999, Jan-05, Volume: 62, Issue:1

    Topics: Acetates; Alkaloids; Biotechnology; Cell Division; Cells, Cultured; Cyclopentanes; Kinetics; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Taxoids

1999
Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m.
    Journal of natural products, 1999, Volume: 62, Issue:10

    Topics: Acetates; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclopentanes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxylipins; Paclitaxel; Taxoids; Trees

1999
The configuration of methyl jasmonate affects paclitaxel and baccatin III production in Taxus cells.
    Phytochemistry, 2000, Volume: 54, Issue:1

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Cell Division; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyclopentanes; Oxylipins; Paclitaxel; Plants, Medicinal; Stereoisomerism; Taxoids; Taxus

2000
Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata.
    Journal of biotechnology, 2003, Mar-06, Volume: 101, Issue:2

    Topics: Acetates; Alkaloids; Cell Survival; Culture Media; Culture Techniques; Cyclopentanes; Fosfomycin; Lovastatin; Oxylipins; Paclitaxel; Quality Control; Taxoids; Taxus

2003
Enhancement of taxol production and release in Taxus chinensis cell cultures by ultrasound, methyl jasmonate and in situ solvent extraction.
    Applied microbiology and biotechnology, 2003, Volume: 62, Issue:2-3

    Topics: Acetates; Cyclopentanes; Dibutyl Phthalate; Oxylipins; Paclitaxel; Plant Growth Regulators; Solvents; Taxus; Ultrasonics

2003
Oxidative burst, jasmonic acid biosynthesis, and taxol production induced by low-energy ultrasound in Taxus chinensis cell suspension cultures.
    Biotechnology and bioengineering, 2004, Mar-30, Volume: 85, Issue:7

    Topics: Cell Culture Techniques; Cell Division; Cell Survival; Cyclopentanes; Enzyme Activation; Intramolecular Oxidoreductases; Lipoxygenase; Oxylipins; Paclitaxel; Plant Stems; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Taxus; Ultrasonics

2004
Mechanosensing and signal transduction in tendrils.
    Advances in space research : the official journal of the Committee on Space Research (COSPAR), 2003, Volume: 32, Issue:8

    Topics: Alamethicin; Bryonia; Cell Wall; Colchicine; Cyclopentanes; Cytochalasin D; Cytoskeleton; Indoleacetic Acids; Mechanotransduction, Cellular; Microtubules; NAD; NADPH Oxidases; Oxylipins; Paclitaxel; Pisum sativum; Plant Components, Aerial; Plant Growth Regulators; Signal Transduction; Stress, Mechanical; Tubulin Modulators; Uncoupling Agents; Vinblastine

2003
Nitric oxide is involved in methyl jasmonate-induced defense responses and secondary metabolism activities of Taxus cells.
    Plant & cell physiology, 2005, Volume: 46, Issue:6

    Topics: Acetates; Cyclic N-Oxides; Cyclopentanes; Free Radical Scavengers; Hydrogen Peroxide; Imidazoles; Lipid Peroxidation; Lipoxygenase; Models, Biological; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitroprusside; Oxylipins; Paclitaxel; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Signal Transduction; Taxus

2005
Improved Taxol production by combination of inducing factors in suspension cell culture of Taxus baccata.
    Cell biology international, 2006, Volume: 30, Issue:3

    Topics: Acetates; Cell Culture Techniques; Cyclopentanes; Fungi; Oxylipins; Paclitaxel; Salicylic Acid; Taxus

2006
Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures.
    Biotechnology and bioengineering, 2006, Sep-05, Volume: 95, Issue:1

    Topics: Acetates; Cell Proliferation; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Oxylipins; Paclitaxel; Peptide Hormones; Peptides; Plant Growth Regulators; Plant Proteins; Taxus

2006
Lipidomic analysis reveals differential defense responses of Taxus cuspidata cells to two elicitors, methyl jasmonate and cerium (Ce4+).
    Biochimica et biophysica acta, 2008, Volume: 1781, Issue:3

    Topics: Acetates; Apoptosis; Cell Membrane; Cerium; Chromatography, Liquid; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Lipid Metabolism; Models, Biological; Multivariate Analysis; Oxylipins; Paclitaxel; Phospholipase A2 Inhibitors; Phospholipase D; Phospholipases A2; Spectrometry, Mass, Electrospray Ionization; Taxus

2008
Effect of elicitors and a biogenetic precursor on paclitaxel production in cell suspension cultures of Taxus cuspidata var. nana.
    Pakistan journal of biological sciences : PJBS, 2007, Sep-01, Volume: 10, Issue:17

    Topics: Antineoplastic Agents, Phytogenic; Carbohydrates; Cell Culture Techniques; Chemistry, Pharmaceutical; Culture Media; Cyclopentanes; Oxylipins; Paclitaxel; Serine; Taxus

2007
Taxus globosa S. cell lines: initiation, selection and characterization in terms of growth, and of baccatin III and paclitaxel production.
    Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2010, Volume: 34, Issue:1

    Topics: Acetates; Alkaloids; Cell Culture Techniques; Cell Line; Cell Proliferation; Culture Media; Cyclopentanes; Oxylipins; Paclitaxel; Taxoids; Taxus

2010
Flow cytometric methods to investigate culture heterogeneities for plant metabolic engineering.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 643

    Topics: Acetates; Cell Culture Techniques; Cell Nucleus; Cell Separation; Cell Size; Cyclopentanes; DNA, Plant; Flow Cytometry; Genetic Engineering; Oxylipins; Paclitaxel; Phenotype; Protoplasts; Taxus

2010
Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in Taxus suspension cultures.
    Biotechnology journal, 2012, Volume: 7, Issue:3

    Topics: Acetates; Bridged-Ring Compounds; Cell Culture Techniques; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Plant Cells; Plant Proteins; Taxoids; Taxus

2012
Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells.
    BMC genomics, 2012, Apr-24, Volume: 13

    Topics: Acetates; Cell Line; Cyclopentanes; Expressed Sequence Tags; Gene Expression Regulation, Plant; Gene Library; Oxylipins; Paclitaxel; Plant Growth Regulators; Taxus

2012
Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis.
    Plant biology (Stuttgart, Germany), 2013, Volume: 15, Issue:1

    Topics: Acetates; Acetyltransferases; Amino Acid Sequence; Base Sequence; Cells, Cultured; Cyclopentanes; Gene Expression; Gene Expression Regulation, Plant; Gene Library; Molecular Sequence Data; Oxylipins; Paclitaxel; Plant Leaves; Plant Proteins; Promoter Regions, Genetic; RNA Interference; Sequence Analysis, DNA; Sequence Deletion; Taxoids; Taxus; Transcription Factors; Transcriptional Activation; Two-Hybrid System Techniques

2013
Transcriptional profile of Taxus chinensis cells in response to methyl jasmonate.
    BMC genomics, 2012, Jul-02, Volume: 13

    Topics: Acetates; Cells, Cultured; Cyclopentanes; DNA, Complementary; Gene Expression Profiling; Oxylipins; Paclitaxel; Plant Growth Regulators; Propanols; Signal Transduction; Taxoids; Taxus; Transcription, Genetic

2012
Deep sequencing reveals transcriptome re-programming of Taxus × media cells to the elicitation with methyl jasmonate.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Acetates; Cell Line; Cells, Cultured; Computational Biology; Cyclopentanes; Databases, Genetic; Ethylenes; Gene Expression Regulation, Plant; Genes, Plant; High-Throughput Nucleotide Sequencing; MicroRNAs; Molecular Sequence Annotation; Oxylipins; Paclitaxel; Plant Cells; Plant Growth Regulators; Reproducibility of Results; RNA, Messenger; Taxus; Terpenes; Transcriptome

2013
Metabolic engineering of Nicotiana benthamiana for the increased production of taxadiene.
    Plant cell reports, 2014, Volume: 33, Issue:6

    Topics: Acetates; Alkenes; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cyclopentanes; Diterpenes; Gene Silencing; Humans; Isomerases; Metabolic Engineering; Metabolic Networks and Pathways; Nicotiana; Oxylipins; Paclitaxel; Plant Growth Regulators; Polyisoprenyl Phosphates; Taxoids; Taxus

2014
Methyl jasmonate represses growth and affects cell cycle progression in cultured Taxus cells.
    Plant cell reports, 2014, Volume: 33, Issue:9

    Topics: Acetates; Apoptosis; Biomass; Cell Cycle; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Plant Growth Regulators; Plant Proteins; Taxus

2014
Development of a hazel cell culture-based paclitaxel and baccatin III production process on a benchtop scale.
    Journal of biotechnology, 2015, Feb-10, Volume: 195

    Topics: Acetates; Alkaloids; Amino Acids; Antineoplastic Agents; Biomass; Bioreactors; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Corylus; Cyclopentanes; Indenes; Oxylipins; Paclitaxel; Plant Growth Regulators; Taxoids

2015
Transcript profiling of jasmonate-elicited Taxus cells reveals a β-phenylalanine-CoA ligase.
    Plant biotechnology journal, 2016, Volume: 14, Issue:1

    Topics: Amino Acid Sequence; Amplified Fragment Length Polymorphism Analysis; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Computer Simulation; Cyclopentanes; Cytosol; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Genetic Association Studies; Ligases; Models, Molecular; Oxylipins; Paclitaxel; Phenylalanine; Plant Proteins; RNA, Messenger; Sequence Alignment; Tandem Mass Spectrometry; Taxoids; Taxus

2016
Two jasmonate-responsive factors, TcERF12 and TcERF15, respectively act as repressor and activator of tasy gene of taxol biosynthesis in Taxus chinensis.
    Plant molecular biology, 2015, Volume: 89, Issue:4-5

    Topics: 5' Flanking Region; Amino Acid Sequence; Base Sequence; Cyclopentanes; DNA, Plant; Gene Expression Regulation, Plant; Genes, Plant; Molecular Sequence Data; Oxylipins; Paclitaxel; Phylogeny; Plant Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Sequence Homology, Amino Acid; Signal Transduction; Taxus; Transcription Factors; Two-Hybrid System Techniques

2015
Regulation of bolting and identification of the α-tubulin gene family in Brassica rapa L. ssp pekinensis.
    Genetics and molecular research : GMR, 2016, Jan-29, Volume: 15, Issue:1

    Topics: Acetates; Arabidopsis; Base Sequence; Brassica rapa; Cyclopentanes; Exons; Flowers; Gene Expression Regulation, Developmental; Genome, Plant; Gibberellins; Introns; Microtubules; Molecular Sequence Data; Oxylipins; Paclitaxel; Plant Development; Plant Growth Regulators; Plant Proteins; Promoter Regions, Genetic; Protein Isoforms; Sequence Alignment; Tubulin

2016
Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells.
    Biochemical and biophysical research communications, 2019, 01-15, Volume: 508, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Drug Resistance, Neoplasm; Female; Humans; Microtubules; NEDD8 Protein; Ovarian Neoplasms; Paclitaxel; Polymerization; Protein Processing, Post-Translational; Pyrimidines; Ubiquitin-Conjugating Enzymes

2019
Regulation Mechanism of MYC Family Transcription Factors in Jasmonic Acid Signalling Pathway on Taxol Biosynthesis.
    International journal of molecular sciences, 2019, Apr-14, Volume: 20, Issue:8

    Topics: Arabidopsis; Arabidopsis Proteins; Basic Helix-Loop-Helix Transcription Factors; Cyclopentanes; Oxylipins; Paclitaxel; Phylogeny; Plant Proteins; Promoter Regions, Genetic; Signal Transduction; Taxus; Two-Hybrid System Techniques

2019
TcJAV3-TcWRKY26 Cascade Is a Missing Link in the Jasmonate-Activated Expression of Taxol Biosynthesis Gene
    International journal of molecular sciences, 2022, Oct-29, Volume: 23, Issue:21

    Topics: Arabidopsis Proteins; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Taxus

2022
Jasmonic acid stimulates taxane production in cell suspension culture of yew (Taxus x media).
    Planta medica, 2002, Volume: 68, Issue:5

    Topics: 2,4-Dichlorophenoxyacetic Acid; Adenine; Bridged-Ring Compounds; Cells, Cultured; Culture Techniques; Cyclopentanes; Kinetin; Oxylipins; Seeds; Taxoids; Taxus

2002
Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus x media cell cultures.
    Phytochemistry, 2003, Volume: 62, Issue:6

    Topics: Acetates; Alkaloids; Cells, Cultured; Cyclopentanes; Molecular Structure; Oxidation-Reduction; Oxylipins; Taxus

2003
Methyl jasmonate induces changes mimicking anatomical defenses in diverse members of the Pinaceae.
    Tree physiology, 2003, Volume: 23, Issue:6

    Topics: Acetates; Cyclopentanes; Larix; Oxylipins; Picea; Pinaceae; Pinus; Plant Bark; Plant Growth Regulators; Plant Stems; Pseudotsuga; Taxus; Trees

2003
Novel synthetic jasmonates as highly efficient elicitors for taxoid production by suspension cultures of Taxus chinensis.
    Biotechnology and bioengineering, 2004, Jun-05, Volume: 86, Issue:5

    Topics: Cell Culture Techniques; Cell Division; Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Oxylipins; Taxoids; Taxus

2004
Novel chemically synthesized hydroxyl-containing jasmonates as powerful inducing signals for plant secondary metabolism.
    Biotechnology and bioengineering, 2004, Jun-30, Volume: 86, Issue:7

    Topics: Acetates; Cell Line; Cyclopentanes; Esters; Glucosides; Hydrogen Peroxide; Molecular Structure; Oxylipins; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Quantitative Structure-Activity Relationship; Taxoids; Taxus

2004
Novel fluoro- and hydroxyl-containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Acylation; Cells, Cultured; Cyclopentanes; Esterification; Esters; Hydrocarbons, Fluorinated; Oxylipins; Stereoisomerism; Structure-Activity Relationship; Taxoids; Taxus; Time Factors

2004
A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism.
    Applied microbiology and biotechnology, 2005, Volume: 68, Issue:1

    Topics: Cells, Cultured; Cyclopentanes; Hydrocarbons, Fluorinated; Models, Chemical; Molecular Structure; Oxylipins; Signal Transduction; Taxoids; Taxus; Time Factors

2005
Highly efficient strategy for enhancing taxoid production by repeated elicitation with a newly synthesized jasmonate in fed-batch cultivation of Taxus chinensis cells.
    Biotechnology and bioengineering, 2005, May-20, Volume: 90, Issue:4

    Topics: Bioreactors; Cell Culture Techniques; Cyclopentanes; Esters; Oxylipins; Taxoids; Taxus

2005
Novel synthetic 2,6-dichloroisonicotinate derivatives as effective elicitors for inducing the biosynthesis of plant secondary metabolites.
    Applied microbiology and biotechnology, 2006, Volume: 71, Issue:2

    Topics: Biological Assay; Biomass; Cyclopentanes; Isonicotinic Acids; Oxylipins; Plant Growth Regulators; Random Allocation; Taxoids; Taxus

2006
Responses of defense signals, biosynthetic gene transcription and taxoid biosynthesis to elicitation by a novel synthetic jasmonate in cell cultures of Taxus chinensis.
    Biotechnology and bioengineering, 2006, Aug-20, Volume: 94, Issue:6

    Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Farnesyltranstransferase; Gene Expression Regulation, Plant; Isomerases; Oxylipins; Respiratory Burst; Signal Transduction; Taxoids; Taxus; Transcriptional Activation

2006
Molecular cloning and characterization of the yew gene encoding squalene synthase from Taxus cuspidata.
    Journal of biochemistry and molecular biology, 2007, Sep-30, Volume: 40, Issue:5

    Topics: Acetates; Amino Acid Sequence; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; Cyclopentanes; DNA, Complementary; Farnesyl-Diphosphate Farnesyltransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gibberellins; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Oxylipins; Plant Growth Regulators; Plant Proteins; Promoter Regions, Genetic; Protein Structure, Secondary; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Taxus

2007
High throughput sequencing technology reveals that the taxoid elicitor methyl jasmonate regulates microRNA expression in Chinese yew (Taxus chinensis).
    Gene, 2009, May-01, Volume: 436, Issue:1-2

    Topics: Acetates; Cell Line; Chromatography, High Pressure Liquid; Cyclopentanes; Gene Expression Regulation, Plant; MicroRNAs; Oxylipins; Plant Growth Regulators; RNA, Plant; Sequence Analysis, RNA; Taxoids; Taxus

2009
Isolation and characterization of a novel cDNA encoding methyl jasmonate-responsive transcription factor TcAP2 from Taxus cuspidata.
    Biotechnology letters, 2009, Volume: 31, Issue:11

    Topics: Acetates; Amino Acid Sequence; Base Sequence; Cyclopentanes; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Molecular Sequence Data; Organ Specificity; Oxylipins; Phylogeny; Plant Proteins; Protein Binding; Protein Transport; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, Protein; Stress, Physiological; Subcellular Fractions; Taxus; Transcription Factors

2009
Enhancement of taxane production in hairy root culture of Taxus x media var. Hicksii.
    Journal of plant physiology, 2009, Nov-15, Volume: 166, Issue:17

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Benzoates; Biomass; Culture Media; Cyclopentanes; Oxylipins; Phenylalanine; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Taxoids; Taxus; Tissue Culture Techniques

2009
[Enhanced production of taxuyunnanine c in cell suspension cultures of Taxus chinensis by methyl jasmonate elicitation and in situ absorption].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2010, Volume: 26, Issue:2

    Topics: Absorption; Acetates; Acrylic Resins; Cell Culture Techniques; Cyclopentanes; Oxylipins; Polystyrenes; Taxoids; Taxus

2010
Expression profiling of genes involved in Taxuyunnanine C biosynthesis in cell suspension cultures of Taxus chinensis by repeated elicitation with a newly synthesized jasmonate and sucrose feeding.
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2011, Volume: 27, Issue:1

    Topics: Cell Culture Techniques; Culture Media; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Plant Growth Regulators; Sucrose; Taxoids; Taxus; Transcriptome

2011
Coronatine, a more powerful elicitor for inducing taxane biosynthesis in Taxus media cell cultures than methyl jasmonate.
    Journal of plant physiology, 2013, Jan-15, Volume: 170, Issue:2

    Topics: Acetates; Amino Acids; Cells, Cultured; Cyclopentanes; Gene Expression Regulation, Plant; Genes, Plant; Indenes; Oxylipins; Plant Growth Regulators; Taxoids; Taxus

2013
Synergistic effect of cyclodextrins and methyl jasmonate on taxane production in Taxus x media cell cultures.
    Plant biotechnology journal, 2014, Volume: 12, Issue:8

    Topics: Acetates; Biosynthetic Pathways; Bridged-Ring Compounds; Cells, Cultured; Cyclodextrins; Cyclopentanes; Drug Synergism; Gene Expression Regulation, Plant; Oxylipins; Plant Proteins; Taxoids; Taxus

2014
Molecular, structural, and phylogenetic analyses of Taxus chinensis JAZs.
    Gene, 2017, Jul-15, Volume: 620

    Topics: Amino Acid Motifs; Cyclopentanes; Evolution, Molecular; Gene Expression Regulation, Plant; Oxylipins; Phylogeny; Plant Proteins; Taxus; Transcription Factors

2017
Identification and characterization of MYC transcription factors in Taxus sp.
    Gene, 2018, Oct-30, Volume: 675

    Topics: Acetates; Cloning, Molecular; Cyclopentanes; Gene Expression Regulation, Plant; Genes, myc; Genes, Plant; Metabolic Networks and Pathways; Oxylipins; Phylogeny; Taxus; Transcription Factors; Transcriptome

2018