Compounds > paclitaxel

Page last updated: 2024-08-23

paclitaxel and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

paclitaxel has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (11.76)	18.2507
2000's	14 (82.35)	29.6817
2010's	1 (5.88)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Delmulle, L; Keukeleire, DD; Vanden Berghe, T; Vandenabeele, P	1
Leist, M; Nicotera, P; Volbracht, C	1
Baldin, V; Brichese, L; Chadebech, P; Valette, A; Vidal, S	1
Rustgi, AK	1
Blagosklonny, MV	1
Blajeski, AL; Kaufmann, SH; Kottke, TJ	1
Heqing, L; Hong, S; Jiangbo, C; Li, G; Ming, J; Tan, G; Xianghe, L; Yanhong, M	1
Bröker, LE; Ferreira, CG; Giaccone, G; Huisman, C; Kruyt, FA; Postmus, PE; Rodriguez, JA; Smit, EF	1
Dulin, N; Gabai, VL; Hatch, W; Kolenko, VM; Leavis, P; Uzzo, RG; Zvartau, N	1
Choi, JS; Chun, KH; Ham, YM; Joo, SH; Lee, SK	1
Chung, JG; Liao, HH; Lin, KL; Lu, KH; Lue, KH	1
Chou, MC; Chung, JG; Lu, KH; Lue, KH	1
Fawcett, H; Giacomantonio, C; Hoskin, DW; Mader, JS; Robichaud, M	1
Bhalla, K; Blagosklonny, MV; Broude, EV; Demidenko, ZN; Halicka, HD; Li, CJ; Vivo, C	1
Goldman, A; Pommier, Y; Sordet, O	1
Cao, XX; Chen, Q; Chen, ZQ; Li, QQ; Liu, XP; Tang, F; Wang, WJ; Xu, JD; Xu, ZD	1
Bargiela-Iparraguirre, J; Belda-Iniesta, C; Dominguez, G; García Alfonso, P; Gutiérrez-González, A; Perona, R; Sanchez-Perez, I	1

Other Studies

17 other study(ies) available for paclitaxel and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

Article	Year
Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death. Phytotherapy research : PTR, 2008, Volume: 22, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Humulus; Male; Molecular Structure; Plant Extracts; Propiophenones; Prostatic Neoplasms; Xanthones	2008
ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. Molecular medicine (Cambridge, Mass.), 1999, Volume: 5, Issue:7 Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Carrier Proteins; Caspase 3; Caspase Inhibitors; Caspases; Cerebellum; Colchicine; Cyclosporine; Cysteine Proteinase Inhibitors; Deoxyglucose; Dizocilpine Maleate; Energy Metabolism; Enzyme Activation; Enzyme Inhibitors; Glutathione; Mice; Mice, Inbred BALB C; Microfilament Proteins; Microtubules; Neurons; Neuroprotective Agents; Nitroso Compounds; Nocodazole; Oligopeptides; Paclitaxel; Potassium; Protein Biosynthesis; S-Nitrosoglutathione; Tacrolimus; Verapamil	1999
Phosphorylation and proteasome-dependent degradation of Bcl-2 in mitotic-arrested cells after microtubule damage. Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3 Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Leupeptins; Microtubules; Mitosis; Multienzyme Complexes; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Virulence Factors, Bordetella	1999
Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery. The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 7; Caspases; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; ras Proteins; Signal Transduction; Time Factors; Tumor Cells, Cultured	2001
Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells. Leukemia, 2001, Volume: 15, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Cyclosporins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Flavonoids; Hematopoietic Stem Cells; HL-60 Cells; Humans; Jurkat Cells; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Oligopeptides; Paclitaxel; Piperidines; Poly(ADP-ribose) Polymerases; Pyrazines; Substrate Specificity; Thiazoles	2001
A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines. Experimental cell research, 2001, Nov-01, Volume: 270, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Nucleus; Cell Survival; Cysteine Proteinase Inhibitors; Female; Humans; Paclitaxel; Ploidies; Thymidine; Tumor Cells, Cultured	2001
Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells. International journal of cancer, 2002, Jan-10, Volume: 97, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Genes, bcl-2; Humans; Nasopharyngeal Neoplasms; Paclitaxel; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation	2002
Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Arabidopsis Proteins; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 8; Caspase 9; Caspases; Cell Death; Cell Line; Cell Survival; Cytochrome c Group; Cytosol; DNA Damage; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Fatty Acid Desaturases; Genes, Dominant; Humans; Lung Neoplasms; Mitochondria; Models, Biological; Paclitaxel; Poly(ADP-ribose) Polymerases; Propidium; Protein Structure, Tertiary; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Spectrometry, Fluorescence; Time Factors; Transfection; Tumor Cells, Cultured	2002
Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:11 Topics: Active Transport, Cell Nucleus; Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Caspase Inhibitors; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Paclitaxel; Prostatic Neoplasms; Proteins; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Zinc	2002
The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis. The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50 Topics: Acetophenones; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Benzopyrans; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Dominant; Ginsenosides; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Paclitaxel; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Time Factors; Transfection; Up-Regulation	2003
Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel. Clinica chimica acta; international journal of clinical chemistry, 2005, Jul-01, Volume: 357, Issue:1 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Division; Dose-Response Relationship, Drug; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Paclitaxel; Protease Inhibitors	2005
Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS). Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Osteosarcoma; Paclitaxel	2005
Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells. International journal of oncology, 2005, Volume: 27, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 3; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Fibronectins; Humans; Intercellular Adhesion Molecule-1; Intracellular Membranes; Membrane Potentials; Mitochondria; Oligopeptides; Paclitaxel; Reactive Oxygen Species; Time Factors	2005
Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection. Cell death and differentiation, 2006, Volume: 13, Issue:9 Topics: Amino Acid Chloromethyl Ketones; Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Caspase 9; Caspase Inhibitors; Cell Cycle; Cell Line, Tumor; Cytoprotection; Dactinomycin; Doxorubicin; Enzyme Activation; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Paclitaxel; Piperidines; Protein Biosynthesis; RNA, Small Interfering; Transcriptional Activation	2006
Topoisomerase II and tubulin inhibitors both induce the formation of apoptotic topoisomerase I cleavage complexes. Molecular cancer therapeutics, 2006, Volume: 5, Issue:12 Topics: Amino Acid Chloromethyl Ketones; Amsacrine; Apoptosis; Caspase Inhibitors; Caspases; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Paclitaxel; Reactive Oxygen Species; Topoisomerase II Inhibitors; Tubulin Modulators; Vinblastine	2006
The role of P-glycoprotein/cellular prion protein interaction in multidrug-resistant breast cancer cells treated with paclitaxel. Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:3 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Caveolae; Caveolin 1; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Paclitaxel; PrPC Proteins	2009
Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair. Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:3 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 2; Cisplatin; Cyclin B; DNA Repair; Humans; Lymphatic Metastasis; Mitosis; Paclitaxel; Protein Serine-Threonine Kinases; Stomach Neoplasms; Taxoids	2013