p-hydroxyamphetamine and amphetamine

p-hydroxyamphetamine has been researched along with amphetamine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199028 (66.67)18.7374
1990's5 (11.90)18.2507
2000's6 (14.29)29.6817
2010's2 (4.76)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Glennon, RA1
Caccia, S; Jori, A1
Bareggi, SR; Becker, RE; Gomeni, R1
Bareggi, SR; Becker, RE; Genovese, E; Ginsburg, B1
Breese, GR; Kuhn, CM; Schanberg, SM1
Cho, AK; Fischer, JF1
Boulton, AA; Danielson, TJ1
Danielson, TJ; Petrali, EH; Wishart, TB1
Colpaert, FC; Janssen, PA; Kuyps, JJ; Niemegeers, CJ1
Dorris, RL1
Gibb, JW; Hanson, GR; Matsuda, LA1
Doi, Y; Oda, H; Ohmae, M; Shimosato, K; Tomita, M1
Shimosato, K1
Green, CE; LeValley, SE; Tyson, CA1
Terada, M1
Valette, G1
D'Mello, GD; Stolerman, IP1
Philips, SR1
Watkins-Freeman, PA; Wellman, PJ1
Dougan, DF; Duffield, AM; Duffield, PH; Wade, DN1
Baker, GB; Coutts, RT; Prelusky, DB1
Browne, RG; Kuczenski, R; Segal, DS; Weinberger, SB1
Bauer, RH1
Law, MY; Moody, DE2
Carmi, O; McGaugh, JL; Roozendaal, B1
Akiyama, S; al-Dirbashi, O; Kuroda, N; Nakashima, K; Nomura, R1
Kamiyama, S; Kanaya, H; Kato, Y; Matsushima, K; Nagai, T; Takahashi, M1
Al-Dirbashi, O; Irgum, K; Nakashima, K; Qvarnstrom, J1
Law, MY; Moody, DE; Slawson, MH1
Bastos, ML; Carvalho, F; Soares, ME1
LIPSIUS, EI1
AXELROD, J1
VARGA, E; VASTAGH, G1
HANNA, C1
SUMMA, AF; WELSH, LH1
ANGER, G; KADEN, W1
Inoue, H; Inouye, Y; Iwata, YT; Kanamori, T; Kishi, T; Nakahama, T; Ohmae, Y; Tsujikawa, K1
Cheng, HL; Jong, YJ; Ko, WK; Li, JH; Wu, SM1
Arttamangkul, S; Bunzow, JR; Grandy, DK; Reese, EA; Sonders, MS1
Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Costa, VM; Feio-Azevedo, R; Ferreira, LM; Pereira, FC1
Onogi, H1

Other Studies

42 other study(ies) available for p-hydroxyamphetamine and amphetamine

ArticleYear
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
Further studies on brain concentrations of amphetamine and its metabolites in strains of mice showing different sensitivity to pharmacological effects of amphetamine.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:11

    Topics: Amphetamine; Animals; Body Temperature; Brain Chemistry; Fatty Acids, Nonesterified; Homovanillic Acid; Hydroxylation; Mice; Mice, Inbred C3H; p-Hydroxyamphetamine; p-Hydroxynorephedrine

1975
Stereotyped behavior and hyperthermia in dogs: correlation with the levels of amphetamine and p-hydroxyamphetamine in plasma and CSF.
    Psychopharmacology, 1978, Jun-15, Volume: 58, Issue:1

    Topics: Amphetamine; Amphetamines; Animals; Behavior; Body Temperature; Dogs; Humans; Kinetics; Male; p-Hydroxyamphetamine; Stereotyped Behavior

1978
Paradoxical effect of amphetamine in an endogenous model of the hyperkinetic syndrome in a hybrid dog: correlation with amphetamine and p-hydroxyamphetamine blood levels.
    Psychopharmacology, 1979, Apr-25, Volume: 62, Issue:3

    Topics: Amphetamine; Amphetamines; Animals; Behavior, Animal; Body Temperature; Dextroamphetamine; Disease Models, Animal; Dogs; Female; Humans; Hyperkinesis; Kinetics; Male; p-Hydroxyamphetamine; Species Specificity; Stereotyped Behavior; Time Factors

1979
Metabolism of amphetamine by rat brain tissue.
    Biochemical pharmacology, 1978, Feb-01, Volume: 27, Issue:3

    Topics: Amphetamine; Animals; Brain; Cisterna Magna; In Vitro Techniques; Injections; Male; Octopamine; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Phenylpropanolamine; Rats; Tyramine

1978
Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2

    Topics: Amphetamine; Animals; Corpus Striatum; Diffusion; Dopamine; In Vitro Techniques; Kinetics; Male; Models, Biological; p-Hydroxyamphetamine; Rats; Reserpine; Sodium; Stereoisomerism; Temperature

1979
Distribution and occurrence of amphetamine and p-hydroxyamphetamine in tissues of the rat after injection of d-amphetamine sulfate.
    European journal of pharmacology, 1976, Volume: 37, Issue:2

    Topics: Amphetamine; Amphetamines; Animals; Brain; Dansyl Compounds; Dextroamphetamine; Male; p-Hydroxyamphetamine; Rats; Time Factors

1976
The effect of acute and chronic injections of d-amphetamine sulfate and substantia nigra lesions on the distribution of amphetamine and para-hydroxyamphetamine in the rat brain.
    Life sciences, 1976, Oct-15, Volume: 19, Issue:8

    Topics: Amphetamine; Amphetamines; Animals; Brain; Corpus Striatum; Dextroamphetamine; Hippocampus; Hypothalamus; Male; Olfactory Bulb; p-Hydroxyamphetamine; Rats; Substantia Nigra

1976
Discriminative stimulus properties of a low dl-amphetamine dose.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 223, Issue:1

    Topics: Amphetamine; Animals; Discrimination, Psychological; Generalization, Psychological; Haloperidol; p-Hydroxyamphetamine; Rats

1976
Release of 3H-alpha-methyl-m-tyramine from rat striatum in vitro.
    European journal of pharmacology, 1976, Volume: 35, Issue:1

    Topics: Amphetamine; Amphetamines; Animals; Calcium; Female; In Vitro Techniques; p-Hydroxyamphetamine; Potassium; Rats; Reserpine

1976
Neurochemical effects of amphetamine metabolites on central dopaminergic and serotonergic systems.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3

    Topics: Amphetamine; Amphetamines; Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dopamine; Male; Nalidixic Acid; Naphthyridines; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Phenylpropanolamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Time Factors

1989
Biphasic effects of alcohol drinking on methamphetamine metabolism in man.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1988, Volume: 23, Issue:5

    Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Amphetamine; Female; Humans; Hydroxylation; Male; Methamphetamine; p-Hydroxyamphetamine; Substance-Related Disorders

1988
Urinary excretion of p-hydroxylated methamphetamine metabolites in man. II. Effect of alcohol intake on methamphetamine metabolism.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4

    Topics: Adult; Amphetamine; Ethanol; Female; Humans; Hydrogen-Ion Concentration; Male; Methamphetamine; p-Hydroxyamphetamine

1988
Comparison of amphetamine metabolism using isolated hepatocytes from five species including human.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Acetone; Adult; Amphetamine; Animals; Benzoates; Benzoic Acid; Dogs; Female; Hippurates; Humans; Hydroxylation; In Vitro Techniques; Liver; Male; p-Hydroxyamphetamine; Rabbits; Rats; Rats, Inbred Strains; Saimiri; Species Specificity

1986
Determination of methamphetamine and its metabolites in rat tissues by gas chromatography with a nitrogen-phosphorus detector.
    Journal of chromatography, 1985, Jan-18, Volume: 318, Issue:2

    Topics: Amphetamine; Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, Gas; Indicators and Reagents; Liver; Male; Mass Spectrometry; Methamphetamine; p-Hydroxyamphetamine; Rats; Rats, Inbred Strains

1985
[Synergism and antagonism of some sympathomimetic amines towards noradrenaline in vitro. Study on isolated rat seminal vesicle. II].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:10-11-12

    Topics: Amphetamine; Animals; Drug Antagonism; Drug Synergism; Ephedrine; Male; Metaraminol; Norepinephrine; Octopamine; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Rats; Seminal Vesicles; Sympathomimetics; Tyramine

1974
Role of training conditions in discrimination of central nervous system stimulants by rats.
    Psychopharmacology, 1981, Volume: 73, Issue:3

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; p-Hydroxyamphetamine; Rats

1981
Amphetamine, p-hydroxyamphetamine and beta-phenethylamine in mouse brain and urine after (-)- and (+)-deprenyl administration.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:11

    Topics: Amphetamine; Amphetamines; Animals; Biogenic Amines; Brain; Male; Mice; p-Hydroxyamphetamine; Phenethylamines; Selegiline; Stereoisomerism

1981
Effects of 4-hydroxyamphetamine on in vivo brown adipose tissue thermogenesis and feeding behavior in the rat.
    Behavioral neuroscience, 1984, Volume: 98, Issue:6

    Topics: Adipose Tissue, Brown; Amphetamine; Amphetamines; Animals; Appetite Depressants; Body Temperature Regulation; Feeding Behavior; Female; p-Hydroxyamphetamine; Rats

1984
The effects of (+)-amphetamine, alpha-methyltyrosine, and alpha-methylphenylalanine on the concentrations of m-tyramine and alpha-methyl-m-tyramine in rat striatum.
    British journal of pharmacology, 1983, Volume: 80, Issue:2

    Topics: alpha-Methyltyrosine; Amphetamine; Amphetamines; Animals; Corpus Striatum; Male; Methyltyrosines; p-Hydroxyamphetamine; Phenylalanine; Rats; Tyramine

1983
Determination of amphetamine, norephedrine, and their phenolic metabolites in rat brain by gas chromatography.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:6

    Topics: Amphetamine; Animals; Biotransformation; Brain Chemistry; Chromatography, Gas; Male; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Phenylpropanolamine; Rats; Rats, Inbred Strains

1984
Evidence that a behavioral augmentation following repeated amphetamine administration does not involve peripheral mechanisms.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3

    Topics: Amphetamine; Animals; Behavior, Animal; Electroshock; Humans; Male; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Peripheral Nerves; Rats; Rats, Inbred Strains; Stereotyped Behavior; Sympathetic Nervous System; Sympathomimetics

1982
The effects of l-, d-, and parahydroxy-amphetamine on locomotor activity and wall climbing in rats of different ages.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:2

    Topics: Aging; Amphetamine; Amphetamines; Animals; Catecholamines; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Motor Activity; p-Hydroxyamphetamine; Rats

1980
Urinary excretion of amphetamine and 4'-hydroxyamphetamine by Sprague Dawley and dark Agouti rats.
    Life sciences, 1994, Volume: 54, Issue:15

    Topics: Amphetamine; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Hydroxylation; Liver; Male; Mixed Function Oxygenases; p-Hydroxyamphetamine; Rats; Rats, Sprague-Dawley

1994
Adrenocortical suppression blocks the memory-enhancing effects of amphetamine and epinephrine.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Feb-20, Volume: 93, Issue:4

    Topics: Adrenal Cortex; Adrenal Medulla; Amphetamine; Animals; Avoidance Learning; Corticosterone; Depression, Chemical; Epinephrine; Male; Metyrapone; p-Hydroxyamphetamine; Rats; Rats, Sprague-Dawley; Retention, Psychology; Steroid 11-beta-Hydroxylase; Stress, Psychological

1996
Determination of methamphetamine and related compounds by capillary electrophoresis with UV and laser-induced fluorescence detection.
    Journal of chromatography. A, 1998, Mar-06, Volume: 798, Issue:1-2

    Topics: 4-Chloro-7-nitrobenzofurazan; Amphetamine; Electrophoresis, Capillary; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lasers; Methamphetamine; p-Hydroxyamphetamine; Phenethylamines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1998
Urinary output changes in racemic ethylamphetamine and optical activity discrimination in rat urine by HPLC analysis.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1998, Volume: 52, Issue:1

    Topics: Amphetamine; Amphetamines; Animals; Chromatography, High Pressure Liquid; Male; p-Hydroxyamphetamine; Rats; Rats, Wistar; Stereoisomerism; Time Factors

1998
Simple and sensitive high-performance liquid chromatographic determination of methamphetamines in human urine as derivatives of 4-(4,5-diphenyl-1H-imidazol-2-yl) benzoyl chloride, a new fluorescence derivatization reagent.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Aug-07, Volume: 712, Issue:1-2

    Topics: Adult; Amphetamine; Benzoates; Chromatography, High Pressure Liquid; Ephedrine; Female; Fluorescent Dyes; Humans; Imidazoles; Male; Methamphetamine; p-Hydroxyamphetamine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Sympathomimetics

1998
Selective involvement of cytochrome P450 2D subfamily in in vivo 4-hydroxylation of amphetamine in rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:3

    Topics: Amphetamine; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethanol; Hydroxylation; Isoenzymes; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; p-Hydroxyamphetamine; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Sprague-Dawley; Safrole

2000
Urinary excretion of 4-hydroxyamphetamine and amphetamine in male and female Sprague-Dawley and Dark Agouti rats following multiple doses of amphetamine.
    Toxicology letters, 2000, Nov-20, Volume: 117, Issue:3

    Topics: Amphetamine; Animals; Central Nervous System Stimulants; Female; Male; p-Hydroxyamphetamine; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Sex Characteristics; Species Specificity

2000
Determination of amphetamine and its metabolite p-hydroxyamphetamine in rat urine by reversed-phase high-performance liquid chromatography after dabsyl derivatization.
    Biomedical chromatography : BMC, 2001, Volume: 15, Issue:7

    Topics: Amphetamine; Animals; Chromatography, High Pressure Liquid; Hydrolysis; Hydroxylation; Indicators and Reagents; p-Dimethylaminoazobenzene; p-Hydroxyamphetamine; Rats; Sensitivity and Specificity

2001
Paredrine hydrobromide in chronic conjunctivitis.
    American journal of ophthalmology, 1952, Volume: 35, Issue:11

    Topics: Amphetamine; Amphetamines; Conjunctivitis; Humans; p-Hydroxyamphetamine

1952
Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1954, Volume: 110, Issue:3

    Topics: Amphetamine; Amphetamines; Biotransformation; Dextroamphetamine; Humans; Methamphetamine; p-Hydroxyamphetamine; Sympathomimetics

1954
[Bromometric determination of veritol & paredrine (pulsoton)].
    Pharmazeutische Zentralhalle fur Deutschland, 1957, Volume: 96, Issue:4

    Topics: Amphetamine; Amphetamines; Methamphetamine; p-Hydroxyamphetamine

1957
Tachyphylaxis. IV. Some cardiovascular actions of hydroxyamphetamine and related compounds.
    Archives internationales de pharmacodynamie et de therapie, 1960, Nov-01, Volume: 128

    Topics: Amphetamine; Amphetamines; Cardiovascular System; p-Hydroxyamphetamine; Tachyphylaxis

1960
Determination and identification of p-hydroxyamphetamine as the O, N-diacetyl derivative.
    Journal of pharmaceutical sciences, 1963, Volume: 52

    Topics: Amphetamine; Amphetamines; Diacetyl; Humans; p-Hydroxyamphetamine

1963
[Clinical studies on a nor-sympathomimetic (beta-p-hydroxyphenylisopropylamine hydrobromide)].
    Bruns' Beitrage zur klinischen Chirurgie, 1959, Volume: 199

    Topics: Amphetamine; Amphetamines; Biomedical Research; Humans; p-Hydroxyamphetamine; Sympathomimetics

1959
A study of the metabolism of methamphetamine and 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in isolated rat hepatocytes.
    Forensic science international, 2005, Mar-10, Volume: 148, Issue:2-3

    Topics: Amphetamine; Animals; Carboxylic Acids; Cells, Cultured; Central Nervous System Stimulants; DOM 2,5-Dimethoxy-4-Methylamphetamine; Gas Chromatography-Mass Spectrometry; Hallucinogens; Hepatocytes; Male; Methamphetamine; Models, Animal; Molecular Structure; p-Hydroxyamphetamine; Rats; Rats, Wistar; Sympathomimetics

2005
Cation-selective exhaustive injection and sweeping MEKC for direct analysis of methamphetamine and its metabolites in urine.
    Electrophoresis, 2006, Volume: 27, Issue:23

    Topics: Amphetamine; Buffers; Cations; Chromatography, Micellar Electrokinetic Capillary; Flow Injection Analysis; Humans; Methamphetamine; p-Hydroxyamphetamine; Sensitivity and Specificity; Substance Abuse Detection

2006
Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Amphetamine; Animals; Cell Line; Central Nervous System Stimulants; Chimera; Cloning, Molecular; Cyclic AMP; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Methamphetamine; Mice; Organ Culture Techniques; p-Hydroxyamphetamine; Plasmids; Rats; Receptors, G-Protein-Coupled; Species Specificity; Stereoisomerism

2007
Toxicity of the amphetamine metabolites 4-hydroxyamphetamine and 4-hydroxynorephedrine in human dopaminergic differentiated SH-SY5Y cells.
    Toxicology letters, 2017, Mar-05, Volume: 269

    Topics: Acetylcysteine; Amphetamine; Apoptosis; Carnitine; Cell Differentiation; Cell Line; Cell Survival; Cycloheximide; Dopaminergic Neurons; Dose-Response Relationship, Drug; Humans; Lethal Dose 50; Methylphenidate; p-Hydroxyamphetamine; p-Hydroxynorephedrine; Reactive Oxygen Species

2017
[Central Administration of p-Hydroxyamphetamine Produces a Behavioral Stimulant Effect in Rodents: Contribution of Dopamine and Serotonin Neurotransmission].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2023, Volume: 143, Issue:11

    Topics: Amphetamine; Animals; Dopamine; Dose-Response Relationship, Drug; Humans; Methamphetamine; Mice; p-Hydroxyamphetamine; Rats; Reflex, Startle; Rodentia; Serotonin; Synaptic Transmission

2023