Page last updated: 2024-09-03

p(1),p(5)-di(adenosine-5'-)pentaphosphate and adenosine monophosphate

p(1),p(5)-di(adenosine-5'-)pentaphosphate has been researched along with adenosine monophosphate in 23 studies

Compound Research Comparison

Studies
(p(1),p(5)-di(adenosine-5'-)pentaphosphate)
Trials
(p(1),p(5)-di(adenosine-5'-)pentaphosphate)
Recent Studies (post-2010)
(p(1),p(5)-di(adenosine-5'-)pentaphosphate)
Studies
(adenosine monophosphate)
Trials
(adenosine monophosphate)
Recent Studies (post-2010) (adenosine monophosphate)
21522611,4322572,798

Protein Interaction Comparison

ProteinTaxonomyp(1),p(5)-di(adenosine-5'-)pentaphosphate (IC50)adenosine monophosphate (IC50)
Fructose-1,6-bisphosphatase 1Sus scrofa (pig)1.3
Fructose-1,6-bisphosphatase 1Homo sapiens (human)2.6436
Cytochrome P450 2C9 Homo sapiens (human)2.6
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.1
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.44
Histamine H3 receptorRattus norvegicus (Norway rat)0.8

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's12 (52.17)18.2507
2000's4 (17.39)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kisteneff, E; Kolodny, NH; Rapaport, E; Redfield, C1
Müller, CW; Schulz, GE1
Dahnke, T; Nakazawa, A; Tsai, MD; Yan, HG; Zhou, BB1
Casteels, R; Kanmura, Y; Minten, J; Missiaen, L; Van Belle, H; Wuytack, F; Wynants, J1
Bârzu, O; Gilles, AM; Mantsch, HH; Reinstein, J; Rose, T; Saint Girons, I; Surewicz, WK; Wittinghofer, A1
Auer, M; Goody, RS; Klaus, W; Rösch, P1
Delicado, EG; Miras-Portugal, MT; Rodriguez del Castillo, A; Torres, M1
Nealon, DA1
Janssen, AJ; Ruitenbeek, W; Sengers, RC; Stadhouders, AM; Trijbels, JM1
Abele, U; Schulz, GE1
Miras-Portugal, MT; Mora, F; Pintor, J; Porras, A1
Berry, MB; Bilderback, T; Glaser, M; Liang, P; Meador, B; Phillips, GN1
Murthy, VV1
Becker, MA; Mateos, FA; Puig, JG; Torres, RJ1
Gomez De Aranda, I; Marti, E; Mateo, J; Miras-Portugal, MT; Rotllan, P; Solsona, C1
Mezzasoma, I; Minelli, A; Moroni, M1
Assfalg-Machleidt, I; Auerswald, EA; Eckerskorn, C; Machleidt, W; Neth, P; Randak, C1
Berry, MB; Phillips, GN1
Bingham, JB; Schroer, TA1
Min, K; Steghens, J1
Jing, G; Pan, X; Sheng, X; Wang, C; Zhang, Y1
Salafsky, JS1
Dong, Q; Randak, CO; Welsh, MJ1

Other Studies

23 other study(ies) available for p(1),p(5)-di(adenosine-5'-)pentaphosphate and adenosine monophosphate

ArticleYear
Ap4A and Ap5A prefer folded unstacked conformations at pH 4-5, in sharp contrast with Ap2A and Ap3A.
    FEBS letters, 1979, Nov-01, Volume: 107, Issue:1

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Dinucleoside Phosphates; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation

1979
Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 A resolution. A model for a catalytic transition state.
    Journal of molecular biology, 1992, Mar-05, Volume: 224, Issue:1

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Sequence; Binding Sites; Dinucleoside Phosphates; Escherichia coli; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation; Substrate Specificity; X-Ray Diffraction

1992
Mechanism of adenylate kinase. Critical evaluation of the X-ray model and assignment of the AMP site.
    Biochemistry, 1990, Dec-11, Volume: 29, Issue:49

    Topics: Adenosine Monophosphate; Adenylate Kinase; Animals; Arginine; Base Sequence; Binding Sites; Catalysis; Dinucleoside Phosphates; DNA Mutational Analysis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligonucleotides; Protein Conformation; Threonine; X-Ray Diffraction

1990
Measurement of microsomal ATPase activities: a comparison between the inorganic phosphate-release assay and the NADH-coupled enzyme assay.
    Biochimica et biophysica acta, 1989, Jan-27, Volume: 990, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; False Positive Reactions; Kinetics; Microsomes; Muscle, Smooth; NAD; Phosphates; Pyloric Antrum; Pyrophosphatases; Swine

1989
Structural and catalytic role of arginine 88 in Escherichia coli adenylate kinase as evidenced by chemical modification and site-directed mutagenesis.
    The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Arginine; Calorimetry, Differential Scanning; Catalysis; Chemical Phenomena; Chemistry; Dinucleoside Phosphates; Drug Stability; Enzyme Activation; Escherichia coli; Fourier Analysis; Hot Temperature; Kinetics; Microbial Collagenase; Mutation; Phenylglyoxal; Phosphotransferases; Spectrophotometry, Infrared; Structure-Activity Relationship; Thermodynamics

1989
Nucleotide and AP5A complexes of porcine adenylate kinase: A 1H and 19F NMR study.
    Biochemistry, 1989, May-16, Volume: 28, Issue:10

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Binding Sites; Dinucleoside Phosphates; Kinetics; Magnetic Resonance Spectroscopy; Nucleotides; Phosphotransferases; Swine

1989
Subcellular distribution studies of diadenosine polyphosphates--Ap4A and Ap5A--in bovine adrenal medulla: presence in chromaffin granules.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Chromatography, High Pressure Liquid; Cytosol; Dinucleoside Phosphates; Phosphoric Monoester Hydrolases

1988
Relative inhibition of human adenylate kinase and creatine kinase isoenzymes by adenosine 5'-monophosphate and diadenosine pentaphosphate.
    Clinical chemistry, 1985, Volume: 31, Issue:2

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenylate Kinase; Creatine Kinase; Dinucleoside Phosphates; Humans; Isoenzymes; Phosphotransferases

1985
Estimation of energy metabolism in human skeletal muscle homogenate as a diagnostic aid.
    Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Arsenic; Arsenites; Child; Dinucleoside Phosphates; Energy Metabolism; Humans; In Vitro Techniques; Male; Muscles; Muscular Diseases; Phosphocreatine

1981
High-resolution structures of adenylate kinase from yeast ligated with inhibitor Ap5A, showing the pathway of phosphoryl transfer.
    Protein science : a publication of the Protein Society, 1995, Volume: 4, Issue:7

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Sequence; Binding Sites; Crystallization; Crystallography, X-Ray; Dinucleoside Phosphates; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phosphates; Protein Folding; Saccharomyces cerevisiae

1995
Dopamine receptor blockade inhibits the amphetamine-induced release of diadenosine polyphosphates, diadenosine tetraphosphate and diadenosine pentaphosphate, from neostriatum of the conscious rat.
    Journal of neurochemistry, 1995, Volume: 64, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Amphetamine; Animals; Corpus Striatum; Dinucleoside Phosphates; Dopamine Antagonists; Haloperidol; Male; Perfusion; Rats; Rats, Wistar

1995
The closed conformation of a highly flexible protein: the structure of E. coli adenylate kinase with bound AMP and AMPPNP.
    Proteins, 1994, Volume: 19, Issue:3

    Topics: Adenosine Monophosphate; Adenylate Kinase; Adenylyl Imidodiphosphate; Binding Sites; Crystallography, X-Ray; Dinucleoside Phosphates; Escherichia coli; Hydrogen Bonding; Magnesium; Models, Molecular; Motion; Protein Conformation; Water

1994
Adenylate kinase mimics creatine kinase-MM isoenzyme in a CK isoenzyme electrophoresis assay.
    Journal of clinical laboratory analysis, 1994, Volume: 8, Issue:3

    Topics: Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Creatine Kinase; Dinucleoside Phosphates; Electrophoresis, Agar Gel; Humans; Isoenzymes

1994
A simplified method for the determination of phosphoribosylpyrophosphate synthetase activity in hemolysates.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Jan-14, Volume: 224, Issue:1

    Topics: Adenosine Monophosphate; Adenylate Kinase; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Female; Humans; Kinetics; Male; Ribose-Phosphate Pyrophosphokinase

1994
Diadenosine polyphosphate hydrolase from presynaptic plasma membranes of Torpedo electric organ.
    The Biochemical journal, 1997, May-01, Volume: 323 ( Pt 3)

    Topics: Acid Anhydride Hydrolases; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations, Divalent; Diethyl Pyrocarbonate; Dinucleoside Phosphates; Electric Organ; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Nerve Tissue Proteins; Presynaptic Terminals; Pyridoxal Phosphate; Torpedo

1997
Human seminal plasma soluble 5'-nucleotidase: regulatory aspects of the dephosphorylation of nucleoside 5'-monophosphates.
    Biochemical and molecular medicine, 1997, Volume: 61, Issue:1

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Cytidine Monophosphate; Dinucleoside Phosphates; Energy Metabolism; Guanosine Monophosphate; Humans; Inosine Monophosphate; Male; Phosphorylation; Purine Nucleotides; Semen; Solubility; Uridine Monophosphate; Vanadates

1997
A recombinant polypeptide model of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator functions as an active ATPase, GTPase and adenylate kinase.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylate Kinase; Cystic Fibrosis Transmembrane Conductance Regulator; Dinucleoside Phosphates; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine Triphosphate; Peptides; Recombinant Fusion Proteins

1997
Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+.
    Proteins, 1998, Aug-15, Volume: 32, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenylate Kinase; Catalysis; Crystallography, X-Ray; Dinucleoside Phosphates; Enzyme Stability; Geobacillus stearothermophilus; Magnesium; Manganese; Models, Molecular; Protein Binding; Protein Conformation; Temperature; Zinc Fingers

1998
Self-regulated polymerization of the actin-related protein Arp1.
    Current biology : CB, 1999, Feb-25, Volume: 9, Issue:4

    Topics: Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Cattle; Dinucleoside Phosphates; Homeostasis; Kinetics; Macromolecular Substances; Microscopy, Electron; Multiprotein Complexes; Protein Structure, Secondary

1999
ADP is produced by firefly luciferase but its synthesis is independent of the light emitting properties.
    Biochimie, 2001, Volume: 83, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Chromatography, Ion Exchange; Coleoptera; Dinucleoside Phosphates; Electrophoresis, Capillary; Firefly Luciferin; Kinetics; Light; Luciferases; Luminescent Measurements

2001
Conformational and functional significance of residue proline 17 in chicken muscle adenylate kinase.
    FEBS letters, 2001, Nov-23, Volume: 508, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Amino Acid Sequence; Amino Acid Substitution; Anilino Naphthalenesulfonates; Animals; Catalysis; Chickens; Dinucleoside Phosphates; Enzyme Inhibitors; Glycine; Kinetics; Molecular Weight; Muscles; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence; Valine

2001
Second-harmonic generation for studying structural motion of biological molecules in real time and space.
    Physical chemistry chemical physics : PCCP, 2007, Nov-14, Volume: 9, Issue:42

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Crystallography, X-Ray; Cysteine; Dinucleoside Phosphates; Models, Molecular; Protein Conformation

2007
A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating.
    Biophysical journal, 2008, Volume: 95, Issue:11

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Adenosine Triphosphate; Binding Sites; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Dinucleoside Phosphates; Enzyme Inhibitors; HeLa Cells; Humans; Ion Channel Gating; Point Mutation; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary

2008