Page last updated: 2024-08-22

ozone and substance p

ozone has been researched along with substance p in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (56.00)18.2507
2000's7 (28.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chodimella, V; Lang, Z; Murlas, CG; Williams, GJ1
Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M1
Campos, MG; Montaño, LM; Ponce-Monter, H; Segura, P; Selman, M; Vanda, B; Vargas, MH1
Chodimella, V; Murlas, CG; Murphy, TP1
Brain, JD; Jimba, M; Killingsworth, CR; Long, NC; Shore, SA; Skornik, WA1
Chodimella, V; Lang, Z; Murlas, CG1
Eschenbacher, WL; Hamilton, R; Hazbun, ME; Holian, A1
Lee, LY; Morton, RF; Wu, ZX1
Biscione, G; Frew, A; Holgate, S; Krishna, MT; Macleod, D; Meng, QH; Polak, J; Springall, D; Withers, N1
Ansay, M; Delaunois, A; Dessy-Doizé, C; Gustin, P; Montaño, LM; Segura, P; Vargas, MH1
Bonham, AC; Joad, JP; Kott, KS1
Gustin, P; Montaño, LM; Romero, L; Sommer, B; Vargas, MH; Zamudio, P1
Ansay, M; Delaunois, A; Gustin, P; Montaño, LM; Segura, P; Vargas, MH1
Green, JF; Harkema, JR; Hyde, DM; Schelegle, ES; Stovall, MY; Vesely, KR1
Dey, RD; Fedan, JS; Frazer, DG; Maize, DF; Satterfield, BE; Wu, ZX1
Fischer, A; Hanf, G; Kunkel, G; Olze, H; Schierhorn, K; Umland, B1
Alfaro, MF; Hyde, DM; Plopper, CG; Putney, L; Schelegle, ES; Sterner-Kock, A; Stovall, MY; Walby, WF; Wong, VJ1
Dey, RD; Satterfield, BE; Wu, ZX1
Guan, C; Luo, Z; Qi, M; Qin, X; Wu, H; Xiang, Y; Zhang, C1
Alfaro, MF; Hyde, DM; Oslund, KL; Putney, LF; Schelegle, ES; Tyler, NK; Walby, WF1
Barker, JS; Batchelor, TP; Dey, RD; Wu, ZX1
Dey, RD; Hunter, DD; Wu, Z1
Fryer, AD; Hazari, MS; Jacoby, DB; Jacoby, IW; Moulton, BC; Verhein, KC1
Batchelor, TP; Carrell-Jacks, LA; Dey, RD; Hunter, DD1
Barker, JS; Dey, RD; Hunter, DD; Wu, Z1

Other Studies

25 other study(ies) available for ozone and substance p

ArticleYear
Aerosolized neutral endopeptidase reverses ozone-induced airway hyperreactivity to substance P.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:3

    Topics: Aerosols; Airway Resistance; Animals; Glycopeptides; Guinea Pigs; Male; Mucous Membrane; Neprilysin; Ozone; Respiratory System; Substance P

1992
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:1

    Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve

1992
O3-induced airway hyperresponsiveness to noncholinergic system and other stimuli.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:1

    Topics: Animals; Autonomic Nervous System; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Ovalbumin; Ozone; Substance P; Trachea; Vagus Nerve

1992
O3-induced mucosa-linked airway muscle hyperresponsiveness in the guinea pig.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 69, Issue:1

    Topics: Acetylcholine; Airway Resistance; Animals; Guinea Pigs; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Neprilysin; Ozone; Receptors, Muscarinic; Respiratory Muscles; Substance P; Trachea

1990
Role of C fibers in physiological responses to ozone in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:5

    Topics: Aerosols; Animals; Animals, Newborn; Body Temperature; Capsaicin; Female; Heart Rate; Lung Compliance; Male; Methacholine Chloride; Nerve Fibers; Neurokinin A; Ozone; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Substance P

1995
Dexamethasone reduces tachykinin but not ACh airway hyperreactivity after O3.
    Lung, 1993, Volume: 171, Issue:2

    Topics: Acetylcholine; Airway Resistance; Animals; Anti-Bacterial Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Guinea Pigs; Male; Neprilysin; Oligopeptides; Ozone; Peptides; Substance P; Tachykinins

1993
Ozone-induced increases in substance P and 8-epi-prostaglandin F2 alpha in the airways of human subjects.
    American journal of respiratory cell and molecular biology, 1993, Volume: 9, Issue:5

    Topics: Adult; Bronchoalveolar Lavage Fluid; Complement C3a; Complement C5a; Dinoprost; Female; Humans; Male; Ozone; Substance P

1993
Role of tachykinins in ozone-induced airway hyperresponsiveness to cigarette smoke in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:3

    Topics: Acetylcholine; Animals; Blood Pressure; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-2; Respiratory Mechanics; Substance P; Tachykinins; Tobacco Smoke Pollution

1997
Effects of ozone on epithelium and sensory nerves in the bronchial mucosa of healthy humans.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:3 Pt 1

    Topics: Adult; Afferent Pathways; Biopsy; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Constriction, Pathologic; Epithelium; Exercise; Female; Humans; Inflammation; Male; Mucous Membrane; Oxidants, Photochemical; Ozone; Rest; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase

1997
Ozone-induced stimulation of pulmonary sympathetic fibers: a protective mechanism against edema.
    Toxicology and applied pharmacology, 1997, Volume: 147, Issue:1

    Topics: Acetylcholine; Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Capillary Permeability; Catecholamines; Dose-Response Relationship, Drug; Female; Guanethidine; Lung; Male; Microscopy, Electron; Nerve Fibers; Neuropeptide Y; Ozone; Pulmonary Edema; Pulmonary Wedge Pressure; Rabbits; Substance P; Time Factors

1997
Exposing guinea pigs to ozone for 1 wk enhances responsiveness of rapidly adapting receptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Lung Compliance; Male; Mechanoreceptors; Methacholine Chloride; Muscarinic Agonists; Oxidants, Photochemical; Ozone; Respiratory Mechanics; Substance P

1998
Chronic exposure to ozone causes tolerance to airway hyperresponsiveness in guinea pigs: lack of SOD role.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:5

    Topics: Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cell Count; Glycopeptides; Guinea Pigs; Inflammation; Infusions, Intravenous; Insufflation; Leukocytes; Lung; Macrophages; Male; Ozone; Substance P; Superoxide Dismutase

1998
Comparison of ozone-induced effects on lung mechanics and hemodynamics in the rabbit.
    Toxicology and applied pharmacology, 1998, Volume: 150, Issue:1

    Topics: Acetylcholine; Air Pollutants; Airway Resistance; Animals; Dose-Response Relationship, Drug; Female; Hemodynamics; Histamine; In Vitro Techniques; Lung; Lung Compliance; Male; Ozone; Pulmonary Circulation; Rabbits; Respiratory Mechanics; Substance P

1998
Capsaicin-sensitive C-fiber-mediated protective responses in ozone inhalation in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 86, Issue:3

    Topics: Administration, Inhalation; Animals; Antimetabolites; Bromodeoxyuridine; Capsaicin; Epithelium; Female; Lung; Nasal Cavity; Nerve Fibers; Oxidants, Photochemical; Ozone; Pregnancy; Rats; Rats, Wistar; Respiratory Mechanics; Respiratory System; Substance P; Tidal Volume; Trachea

1999
Role of intrinsic airway neurons in ozone-induced airway hyperresponsiveness in ferret trachea.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:1

    Topics: Acetylcholine; Animals; Cholinergic Agonists; Culture Techniques; Electric Stimulation; Female; Ferrets; Methacholine Chloride; Muscarinic Agonists; Neurokinin-1 Receptor Antagonists; Neurons; Ozone; Piperidines; Substance P; Trachea; Tracheal Diseases

2001
Ozone-induced release of neuropeptides from human nasal mucosa cells.
    International archives of allergy and immunology, 2002, Volume: 129, Issue:2

    Topics: Biopsy; Culture Techniques; Humans; Immunoenzyme Techniques; Immunohistochemistry; Microscopy, Confocal; Nasal Mucosa; Neurokinin A; Ozone; Rhinitis, Allergic, Perennial; Statistics, Nonparametric; Substance P

2002
Repeated episodes of ozone inhalation attenuates airway injury/repair and release of substance P, but not adaptation.
    Toxicology and applied pharmacology, 2003, Feb-01, Volume: 186, Issue:3

    Topics: Adaptation, Physiological; Administration, Inhalation; Animals; Bronchi; Bronchoalveolar Lavage; Cell Division; Epithelial Cells; Epithelium; Logistic Models; Lung; Male; Oxidants, Photochemical; Ozone; Rats; Respiration; Substance P; Time Factors; Trachea

2003
Substance P released from intrinsic airway neurons contributes to ozone-enhanced airway hyperresponsiveness in ferret trachea.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:2

    Topics: Animals; Capsaicin; Electric Stimulation; Female; Ferrets; Ganglia; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Neurons; Ozone; Piperidines; Substance P; Trachea

2003
Upregulation of substance P receptor expression by calcitonin gene-related peptide, a possible cooperative action of two neuropeptides involved in airway inflammation.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:5

    Topics: Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Guinea Pigs; Humans; Inflammation; Lung; Ozone; Protein-Tyrosine Kinases; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Substance P; Up-Regulation

2007
Activation of neurokinin-1 receptors during ozone inhalation contributes to epithelial injury and repair.
    American journal of respiratory cell and molecular biology, 2008, Volume: 39, Issue:3

    Topics: Animals; Apoptosis; Bronchi; Immunohistochemistry; Inhalation; Male; Neurokinin-1 Receptor Antagonists; Ozone; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Respiratory Mucosa; Substance P; Trachea

2008
Interleukin (IL)-1 regulates ozone-enhanced tracheal smooth muscle responsiveness by increasing substance P (SP) production in intrinsic airway neurons of ferret.
    Respiratory physiology & neurobiology, 2008, Dec-31, Volume: 164, Issue:3

    Topics: Analysis of Variance; Animals; Antirheumatic Agents; Biophysics; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Female; Ganglia, Autonomic; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Methacholine Chloride; Muscarinic Agonists; Muscle, Smooth; Neurons; Organ Culture Techniques; Oxidants, Photochemical; Ozone; Substance P; Trachea

2008
Sensory neural responses to ozone exposure during early postnatal development in rat airways.
    American journal of respiratory cell and molecular biology, 2010, Volume: 43, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Humans; Lung; Muscle, Smooth; Nerve Fibers; Ozone; Rats; Respiratory Function Tests; Sensory Receptor Cells; Substance P; Time Factors

2010
Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 300, Issue:2

    Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Female; Guinea Pigs; Humans; Lung; Male; Models, Biological; Nerve Growth Factor; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Time Factors; Vagus Nerve

2011
Role of nerve growth factor in ozone-induced neural responses in early postnatal airway development.
    American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:2

    Topics: Animals; Animals, Newborn; Blotting, Western; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Nerve Growth Factor; Neurons; Oxidants, Photochemical; Ozone; Rats; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P

2011
Ozone exposure initiates a sequential signaling cascade in airways involving interleukin-1beta release, nerve growth factor secretion, and substance P upregulation.
    Journal of toxicology and environmental health. Part A, 2015, Volume: 78, Issue:6

    Topics: Air Pollutants; Animals; Bronchoalveolar Lavage Fluid; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Nerve Growth Factor; Ozone; Respiratory System; Sensory Receptor Cells; Signal Transduction; Substance P; Up-Regulation

2015