Page last updated: 2024-08-22

ozone and indomethacin

ozone has been researched along with indomethacin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199010 (37.04)18.7374
1990's10 (37.04)18.2507
2000's6 (22.22)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benson, J; Giri, SN; Rice, SA; Schiedt, M; Siegel, DM1
Bhalla, DK; Daniels, DS; Luu, NT1
Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M1
Hudak, BB; Kleeberger, SR1
Chen, LC; Gunnison, AF; Koenig, KL; Sobo, M; Weideman, PA1
Daniel, EE; Janssen, LJ; O'Byrne, PM1
Canning, BJ; Hmieleski, RR; Jakab, GJ; Spannhake, EW1
Eschenbacher, WL; Gross, KB; Terzo, TS; Ying, RL1
Payne, AN; Yeadon, M1
Gordon, T; Sheppard, D; Thompson, JE1
Ainsworth, D; Amdur, MO; Lam, HF; Miller, PD1
Lee, HK; Murlas, C; Roum, JH1
Adams, WC; Schelegle, ES; Siefkin, AD1
Lee, HK; Murlas, C1
Friedman, M; Gammon, K; Kwock, L; Madden, MC; Saunders, DS; White, GC1
Aizawa, H; Fabbri, LM; Holtzman, MJ; Nadel, JA; O'Byrne, PM; Walters, EH1
Bromberger-Barnea, B; Dannenberg, AM; Gertner, A; Menkes, H; Traystman, R1
Croxton, TL; Kleeberger, SR; Takahashi, M1
Daniel, EE; Jones, GL; Montaño, LM; O'Byrne, PM1
Fryer, AD; Jacoby, DB; Kahn, RM; Okanlami, OA1
Alexis, N; Corey, P; O'Byrne, P; Pengelly, D; Silverman, F; Tarlo, S; Urch, B1
Arakawa, H; Kato, M; Mochizuki, H; Morikawa, A; Ohki, Y; Tokuyama, K1
Paz, C; Rubio, C1
Adams, WC; Schelegle, ES; Walby, WF1
Alonso, Y; González, R; Guanche, D; Hernández, F; Menéndez, S; Merino, N; Schulz, S; Zamora, Z1
Damera, G; Jester, WF; Kirby, C; Lawson, JA; Panettieri, RA; Smith, M; Wang, M; Zhao, H1
Deng, S; Huang, J; Kuang, J; Li, X; Wang, B; Wang, Y; Yu, G; Zhang, S; Zhao, Y1

Trials

2 trial(s) available for ozone and indomethacin

ArticleYear
Indomethacin does not inhibit the ozone-induced increase in bronchial responsiveness in human subjects.
    The American review of respiratory disease, 1990, Volume: 142, Issue:4

    Topics: Adolescent; Adult; Airway Resistance; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Forced Expiratory Volume; Humans; Indomethacin; Male; Methacholine Chloride; Ozone; Random Allocation; Vital Capacity

1990
Indomethacin pretreatment reduces ozone-induced pulmonary function decrements in human subjects.
    The American review of respiratory disease, 1987, Volume: 136, Issue:6

    Topics: Adult; Anthropometry; Double-Blind Method; Drug Interactions; Exercise Test; Humans; Indomethacin; Lung; Male; Ozone; Random Allocation; Respiratory Function Tests; Time Factors

1987

Other Studies

25 other study(ies) available for ozone and indomethacin

ArticleYear
Effects of pretreatment with anti-inflammatory drugs on ozone-induced lung damage in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Heparin; Hydrocortisone; Indomethacin; Male; Ozone; Prostaglandins; Pulmonary Edema; Rats

1975
Attenuation of ozone-induced airway permeability in rats by pretreatment with cyclophosphamide, FPL 55712, and indomethacin.
    American journal of respiratory cell and molecular biology, 1992, Volume: 7, Issue:1

    Topics: Albumins; Animals; Blood Proteins; Bronchoalveolar Lavage Fluid; Chromones; Cyclophosphamide; Indomethacin; Leukocyte Count; Leukopenia; Leukotriene B4; Male; Ozone; Permeability; Pulmonary Alveoli; Rats; Rats, Inbred F344; Technetium Tc 99m Pentetate; Trachea

1992
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:1

    Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve

1992
Acute ozone-induced change in airway permeability: role of infiltrating leukocytes.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Colchicine; Cyclophosphamide; Indomethacin; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Neutrophils; Ozone; Permeability; Pneumonia; Proteins

1992
Age-dependence of responses to acute ozone exposure in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Dinoprostone; Indomethacin; L-Lactate Dehydrogenase; Leukocytes; Lung; Ozone; Prostaglandins; Prostaglandins F; Proteins; Rats; Rats, Inbred Strains; Total Lung Capacity

1992
Mechanism underlying ozone-induced in vitro hyperresponsiveness in canine bronchi.
    The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 1

    Topics: Administration, Inhalation; Animals; Bronchi; Bronchial Diseases; Bronchoconstriction; Dogs; Electric Stimulation; Indomethacin; Muscle, Smooth; Neuromuscular Junction; Organ Size; Ozone; Respiratory Hypersensitivity; Thromboxane A2

1991
Ozone reduces murine alveolar and peritoneal macrophage phagocytosis: the role of prostanoids.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Adhesion; Cyclooxygenase Inhibitors; Indomethacin; Macrophages; Mice; Ozone; Peritoneal Cavity; Phagocytosis; Prostaglandins; Prostaglandins E; Proteins; Pulmonary Alveoli

1991
Ascorbic acid prevents ozone-induced bronchial hyperreactivity in guinea-pigs.
    British journal of pharmacology, 1989, Volume: 98 Suppl

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Ascorbic Acid; Bronchi; Guinea Pigs; In Vitro Techniques; Indomethacin; Ozone

1989
Arachidonic acid metabolites do not mediate toluene diisocyanate-induced airway hyperresponsiveness in guinea pigs.
    Prostaglandins, 1988, Volume: 35, Issue:5

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Airway Obstruction; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dogs; Drug Synergism; Epoprostenol; Guinea Pigs; Indomethacin; Male; Ozone; Pyrazoles; Respiratory System; Toluene 2,4-Diisocyanate

1988
Indomethacin and cromolyn sodium alter ozone-induced changes in lung function and plasma eicosanoid concentrations in guinea pigs.
    Toxicology and applied pharmacology, 1988, Volume: 93, Issue:2

    Topics: Animals; Body Weight; Cromolyn Sodium; Guinea Pigs; Indomethacin; Lung; Male; Organ Size; Ozone; Prostaglandins; Pulmonary Diffusing Capacity; Thromboxanes; Total Lung Capacity

1988
Indomethacin increases bronchial reactivity after exposure to subthreshold ozone levels.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 21, Issue:3

    Topics: Acetylcholine; Airway Resistance; Animals; Bronchi; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Injections, Intraperitoneal; Injections, Intravenous; Male; Ozone; Receptors, Muscarinic; Respiration

1986
Ozone-induced bronchial hyperreactivity in guinea pigs is abolished by BW 755C or FPL 55712 but not by indomethacin.
    The American review of respiratory disease, 1985, Volume: 132, Issue:5

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Airway Resistance; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lipoxygenase; Male; Ozone; Pyrazoles; SRS-A

1985
Ozone inhibits prostacyclin synthesis in pulmonary endothelium.
    Prostaglandins, 1985, Volume: 30, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Cells, Cultured; Endothelium; Epoprostenol; Hypoxia; Indomethacin; Lung; Ozone; Vascular Resistance; Vasoconstriction

1985
Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx induced by ozone in dogs.
    The American review of respiratory disease, 1984, Volume: 130, Issue:2

    Topics: Animals; Cell Count; Dogs; Indomethacin; Mucous Membrane; Neutrophils; Ozone; Respiratory Hypersensitivity; Trachea

1984
Responses of the lung periphery to 1.0 ppm ozone.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 55, Issue:3

    Topics: Animals; Chlorpheniramine; Dogs; Indomethacin; Lung; Male; Nerve Block; Ozone; Parasympathetic Nervous System

1983
Ozone-induced decrease of mouse tracheal potential is not secondary to cellular inflammation.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:1

    Topics: Animals; Bronchoalveolar Lavage Fluid; Colchicine; Cyclophosphamide; Electrophysiology; Epithelium; Indomethacin; Inflammation; Male; Mice; Mice, Inbred Strains; Neutrophils; Ozone; Proteins; Trachea

1995
Effect of ozone exposure in vivo on response of bronchial rings in vitro: role of intracellular Ca2+.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:3

    Topics: Animals; Bronchi; Bronchoconstriction; Calcium; Carbachol; Culture Media; Dogs; Extracellular Space; Indoles; Indomethacin; Intracellular Membranes; Ozone

1993
Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung.
    The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2

    Topics: Animals; Antibodies, Viral; Benzoquinones; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; Heart Rate; Indans; Indomethacin; Inflammation; Lung; Lung Diseases; Macaca mulatta; Neurons; Ozone; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Pilocarpine; Prostaglandin-Endoperoxide Synthases; Receptor, Muscarinic M2; Receptors, Muscarinic; Vagus Nerve

1996
Cyclooxygenase metabolites play a different role in ozone-induced pulmonary function decline in asthmatics compared to normals.
    Inhalation toxicology, 2000, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Asthma; Dinoprost; Female; Humans; Indomethacin; Lung; Male; Ozone; Prostaglandin-Endoperoxide Synthases; Sputum

2000
Effect of inhaled indomethacin on distilled water-induced airway epithelial cell swelling.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 92, Issue:1

    Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Size; Epithelial Cells; Guinea Pigs; Indomethacin; Intubation, Intratracheal; Ion Channels; Male; Nebulizers and Vaporizers; Neutrophils; Oxidants, Photochemical; Ozone; Prostaglandins; Respiratory System; Water

2002
Indomethacin reverts sleep disorders produced by ozone exposure in rats.
    Toxicology, 2003, Sep-30, Volume: 191, Issue:2-3

    Topics: Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Electroencephalography; Electrooculography; Indomethacin; Male; Oxidants, Photochemical; Ozone; Polysomnography; Prostaglandins; Rats; Rats, Wistar; Sleep; Sleep Wake Disorders; Sleep, REM

2003
Time course of ozone-induced changes in breathing pattern in healthy exercising humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Air Pollutants; Atropine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Exercise; Female; Forced Expiratory Volume; Humans; Indomethacin; Linear Models; Male; Middle Aged; Muscarinic Antagonists; Ozone; Respiration Disorders; Respiratory Mechanics; Time Factors; Vital Capacity

2007
Ozonized sunflower oil reduces oxidative damage induced by indomethacin in rat gastric mucosa.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57, Issue:1

    Topics: Animals; Gastric Mucosa; Indomethacin; Lipid Peroxidation; Male; Oxidative Stress; Ozone; Plant Oils; Rats; Rats, Sprague-Dawley; Sunflower Oil; Superoxide Dismutase

2008
Ozone modulates IL-6 secretion in human airway epithelial and smooth muscle cells.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:4

    Topics: Cell Differentiation; Cell Line; Coculture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Electric Impedance; Epithelial Cells; Humans; Indomethacin; Interleukin-6; Lung; Mucins; Myocytes, Smooth Muscle; Ozone; Permeability; Tumor Necrosis Factor-alpha

2009
Ozonation of indomethacin: Kinetics, mechanisms and toxicity.
    Journal of hazardous materials, 2017, Feb-05, Volume: 323, Issue:Pt A

    Topics: Drug Residues; Indomethacin; Kinetics; Nitrogen; Ozone; Photobacterium; Water Pollutants, Chemical; Water Purification

2017